This lesson describes the principles of cell fractionation and ultracentrifugation as used to separate cell components. The engaging PowerPoint and accompanying resources are part of the final lesson in a series of 4 lessons which have been planned to cover the details of point 2.1.3 of the AQA A-level biology specification.
This lesson begins by informing the students that several of the key terms in this lesson, including the lesson title, end in -ation, and therefore they have to use the clues to work out that the 1st one is cell fractionation. A quiz round like this runs throughout the lesson, introducing homogenisation, filtration and ultracentrifugation in a memorable way. Time is taken to explain each of the processes in detail, and where possible, links are made to previously covered content as well as content that will be met in future lessons. For example, students will learn that the solution must be kept ice-cold and isotonic, and they are challenged to recognise that the low temperature is to reduce the activity of potentially damaging enzymes, before being told that there will be no net movement of water by osmosis because of the isotonic solution. The answers to all understanding and prior knowledge checks are embedded into the PowerPoint to allow students to assess their progress. When explaining the process of ultracentrifugation, the students are given an opportunity to predict which of 6 listed organelles will be found in the 1st pellet because it is the heaviest, right down to the lightest organelle. The lesson finishes with several exam-style questions to check that they’ve understood this separation technique and have a strong knowledge of cells and their organelles.
This lesson has been planned to continously link with the other lessons in topic 2.1 (Cell structure).
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Topic 2: Cells (AQA A-level Biology)
This bundle contains 20 PowerPoint lessons, and all are highly-detailed and are fully-resourced with differentiated worksheets. Intricate planning means that the wide range of activities included in these lessons will engage and motivate the students, check on their current understanding and their ability to make links to previously covered topics and most importantly will deepen their understanding of the following specification points in topic 2 (Cells) of the AQA A-level Biology specification: * Structure and function of the organelles in eukaryotic cells * The specialised cells in complex, multicellular organisms * The structure of prokaryotic cells * The structure of viruses which are acellular and non-living * Measuring objects under an optical microscope * Use of the magnification formula * The principles of cell fractionation and ultracentrifugation * The behaviour of chromosomes during the stages of the cell cycle * Calculating the mitotic index * Uncontrolled cell division leads to the formation of tumours and cancer * Binary fission * The basic structure of cell membranes * The role of phospholipids, proteins, glycoproteins, glycolipids and cholesterol * Simple diffusion * Facilitated diffusion * Osmosis, explained in terms of water potential * The role of carrier proteins and the hydrolysis of ATP in active transport * Co-transport as illustrated by the absorption of sodium ions and glucose by the cells lining the mammalian ileum * Recognition of different cells by the immune system * The identification of pathogens from antigens * The phagocytosis of pathogens * The cellular response involving T lymphocytes * The humoral response involving the production of antibodies by plasma cells * The structure of an antibody * The roles of plasma cells and memory cells in the primary and secondary immune response * The use of vaccines to protect populations * The differences between active and passive immunity * The structure of the human immunodeficiency virus and its replication in helper T cells * Why antibiotics are ineffective against viruses * The use of antibodies in the ELISA test If you would like to sample the quality of these lessons, then download the eukaryotic animal cells, viruses, osmosis, lymphocytes, HIV and AIDS lessons as these have been shared for free. I have also uploaded lessons on optical microscopes and HIV and AIDS (for free) but neither are included in this bundle as the limit of 20 resources has been reached!
£30.00
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Methods of studying cells (AQA A-level biology)
This bundle of 4 lessons have been intricately planned to cover the detailed content of topic 2.1.3 of the AQA A-level biology specification. This topic, titled "methods of studying cells", isn't every student's cup of tea, so the lessons have been deliberately filled with a range of engaging tasks, including a quiz competition that runs across the 4 lessons. These quizzes act to introduce key terms and numbers in a memorable way and also check on knowledge from the current lesson or previous topics. If you would like to observe the quality of lessons in this bundle, then download the optical and electron microscopes lesson as this has been uploaded for free.
£7.50
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Topic 2.1: Cell structure (AQA A-level Biology)
This bundle of 9 lesson PowerPoints and accompanying resources contain a wide variety of tasks which will engage and motivate the students whilst covering the details of topic 2.1 of the AQA A-level Biology specification. Cells and their structure are linked to all of the other 7 topics in this course so a clear understanding is critical to a student's success. The tasks which include exam-style questions (with displayed mark schemes), discussion points and quiz competitions will cover the following parts of topic 2.1: * The structure and function of the cell-surface membrane, nucleus, nucleolus, mitochondria, chloroplasts, Golgi apparatus, lysosomes, ribosomes, RER and SER, cell wall and cell vacuole * The specialised cells of complex, multicellular organisms * The structures of a typical prokaryotic cell * The differences between prokaryotic and eukaryotic cells * The structure of viruses * The principles and limitations of optical microscopes, transmission electron microscopes and scanning electron microscopes * Measuring the size of an object using an optical microscope * Using the magnification formula * The principles of cell fractionation and ultracentrifugation If you would like to sample the quality of these lessons, then download the eukaryotic animal cells, viruses and microscopes lessons as these have been uploaded for free
£14.00
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