DNA methylation and histone modification (Edexcel Int. A-level biology)

Topic 3: Cell structure, Reproduction & Development (Edexcel International A-level Biology)

The locus and linkage, meiosis, differential gene expression and protein transport within cells lessons have been uploaded for free and by downloading these, you will be able to observe the detail of planning that has gone into all of the lessons that are included in this bundle. This intricate planning ensures that the students are engaged and motivated whilst the detailed content of topic 3 (Cell structure, Reproduction and Development) of the Edexcel International A-level Biology specification is covered. The 14 lesson PowerPoints and accompanying resources contain a wide range of activities which cover the following topic 3 specification points: * All living organisms are made of cells * Cells of multicellular organisms are organised into tissues, organs and organ systems * The ultrastructure of eukaryotic cells * The function of the organelles in eukaryotic animal cells * The role of the RER and Golgi apparatus in protein transport within cells * The ultrastructure of prokaryotic cells * Magnification and resolution in light and electron microscopes * The gene locus is the location of a gene on a chromosome * The linkage of genes on a chromosome * The role of meiosis in ensuring genetic variation * Understand how the mammalian gametes are specialised for their functions * The role of mitosis and the cell cycle in growth and asexual reproduction * Calculation of mitotic indices * The meaning of the terms stem cell, pluripotent, totipotent, morula and blastocyst * The decisions that have to be made about the use of stem cells in medical therapies * Cells become specialised through differential gene expression * One gene can give rise to more than one protein through post-transcriptional changes to mRNA * Phenotype is the interaction between genotype and the environment * Epigenetic modifications can alter the activation of certain genes * Some phenotypes are affected by multiple alleles or by polygenic inheritance Due to the detail included in all of these lessons, it is estimated that it will take in excess of 6 weeks of allocated A-level teaching time to complete the teaching of the bundle