This fully-resourced lesson describes how DNA is replicated semi-conservatively, including the roles of DNA helicase, polymerase and ligase. The detailed PowerPoint and accompanying resources have been designed to cover point 1.4 (ii) of the Edexcel A-level Biology B specification
The main focus of this lesson is the roles of DNA helicase in the breaking of the hydrogen bonds between nucleotide bases, DNA polymerase in forming the growing nucleotide strands and DNA ligase in the joining of the nucleic acid fragments. Time is taken to explain key details, such as the assembly of strands in the 5’-to-3’ direction, so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure and hydrolysis reactions through a range of exam questions and answers are displayed so that any misconceptions are quickly addressed. The main task of the lesson asks the students to use the information provided in the lesson to order the sequence of events in DNA replication before discussing how the presence of a conserved strand and a newly built strand in each new DNA molecule shows that it is semi-conservative.
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Topic 1: Biological molecules (Edexcel A-level Biology B)
The biological molecules topic is incredibly important, not just because it is found at the start of the course, but also because of its detailed content which must be well understood to promote success with the other 9 Edexcel A-level Biology B topics. Many hours of intricate planning has gone into the design of all of the 19 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: * The differences between monosaccharides, disaccharides and polysaccharides * The structure of glucose and ribose * The formation of disaccharides and polysaccharides from monosaccharides * The structure of starch, glycogen and cellulose * The synthesis of a triglyceride * The differences between saturated and unsaturated lipids * The relationship between the structure of lipids and their roles * The structure and properties of phospholipids * The structure of an amino acid * The formation of polypeptides and proteins * The role of ionic, hydrogen and disulphide bonding in proteins * The levels of protein structure * The structure of collagen and haemoglobin * The structure of DNA * The semi-conservative replication of DNA * A gene is a sequence of bases on DNA that codes for an amino acid sequence * The structure of mRNA * The structure of tRNA * The process of transcription * The process of translation * Base deletions, insertions and substitutions as gene mutations * The effect of point mutations on amino acid sequences * The structure of enzymes as globular proteins * The concept of specificity and the induced-fit hypothesis * Enzymes are catalysts that reduce activation energy * Understand how temperature affects enzyme activity * Enzymes catalyse a wide range of intracellular reactions as well as extracellular ones * The role of inorganic ions in plants * The importance of water for living organisms Due to the detail included in these lessons, it is estimated that it will take in excess of 2 months of allocated A-level teaching time to complete. If you would like to see the quality of the lessons then download the monosaccharides, disaccharides and polysaccharides, glucose and ribose, triglycerides, structure of DNA and transcription lessons as these have been uploaded for free.
£26.00
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Topic 1.4: DNA and protein synthesis (Edexcel A-level Biology B)
This bundle of 6 fully-resourced lessons have been designed to cover the content as detailed in topic 1.4 of the Edexcel A-level Biology B specification. The specification points in this DNA and protein synthesis topic which are covered by the lessons are as follows: * The structure of DNA * The semi-conservative replication of DNA * A gene is a sequence of bases on DNA that codes for an amino acid sequence * The structure of mRNA * The structure of tRNA * The process of transcription * The process of translation * Base deletions, insertions and substitutions as gene mutations * The effect of point mutations on amino acid sequences The engaging PowerPoint lessons and accompanying resources contain a wide range of activities and tasks that include exam-style questions with displayed mark schemes, quick quiz competitions, useful hints and discussion periods. If you would like to see the quality of the lessons then download the structure of DNA and transcription lessons as these have been uploaded for free.
£7.00
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