This lesson describes the formation of dipeptides & polypeptides and the different levels of protein structure. Both the engaging PowerPoint and accompanying resources have been designed to cover specification points 1.3 (ii), (iii) & (iv) of the Edexcel A-level Biology B specification and also makes continual links to previous lessons such as amino acids as well as to upcoming lessons like antibodies and enzymes so students can understand where proteins are involved.
The start of the lesson focuses on the formation of a peptide bond during a condensation reaction so that students can understand how a dipeptide is formed and therefore how a polypeptide forms when multiple reactions occur.
The main part of the lesson describes the different levels of protein structure. A step by step guide is used to demonstrate how the sequences of bases in a gene acts as a template to form a sequence of codons on a mRNA strand and how this is translated into a particular sequence of amino acids known as the primary structure. The students are then challenged to apply their understanding of this process by using three more gene sequences to work out three primary structures and recognise how different genes lead to different sequences. Moving forwards, students will learn how the order of amino acids in the primary structure determines the shape of the protein molecule, through its secondary, tertiary and quaternary structure and time is taken to consider the details of each of these. There is a particular focus on the different bonds that hold the 3D shape firmly in place and a quick quiz round then introduces the importance of this shape as exemplified by enzymes, antibodies and hormones. Students will see the differences between globular and fibrous protein and again biological examples are used to increase relevance. The lesson concludes with one final quiz round called STRUC by NUMBERS where the students have to use their understanding of the protein structures to calculate a numerical answer.
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Topic 1: Biological molecules (Edexcel A-level Biology B)
The biological molecules topic is incredibly important, not just because it is found at the start of the course, but also because of its detailed content which must be well understood to promote success with the other 9 Edexcel A-level Biology B topics. Many hours of intricate planning has gone into the design of all of the 19 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: * The differences between monosaccharides, disaccharides and polysaccharides * The structure of glucose and ribose * The formation of disaccharides and polysaccharides from monosaccharides * The structure of starch, glycogen and cellulose * The synthesis of a triglyceride * The differences between saturated and unsaturated lipids * The relationship between the structure of lipids and their roles * The structure and properties of phospholipids * The structure of an amino acid * The formation of polypeptides and proteins * The role of ionic, hydrogen and disulphide bonding in proteins * The levels of protein structure * The structure of collagen and haemoglobin * The structure of DNA * The semi-conservative replication of DNA * A gene is a sequence of bases on DNA that codes for an amino acid sequence * The structure of mRNA * The structure of tRNA * The process of transcription * The process of translation * Base deletions, insertions and substitutions as gene mutations * The effect of point mutations on amino acid sequences * The structure of enzymes as globular proteins * The concept of specificity and the induced-fit hypothesis * Enzymes are catalysts that reduce activation energy * Understand how temperature affects enzyme activity * Enzymes catalyse a wide range of intracellular reactions as well as extracellular ones * The role of inorganic ions in plants * The importance of water for living organisms Due to the detail included in these lessons, it is estimated that it will take in excess of 2 months of allocated A-level teaching time to complete. If you would like to see the quality of the lessons then download the monosaccharides, disaccharides and polysaccharides, glucose and ribose, triglycerides, structure of DNA and transcription lessons as these have been uploaded for free.
£26.00
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Topics 1.1, 1.2 & 1.3: Carbohydrates, Lipids & Proteins (Edexcel A-level Biology B)
Carbohydrates, lipids and proteins are the key biological molecules and the specification points covering the relationship between their structures and functions are found in the very first three topics of Edexcel A-level Biology B course. With this in mind, hours of intricate planning has gone into each of the 9 lessons that are included in this bundle to ensure that students are continually engaged whilst the detailed content is covered by the variety of tasks. These tasks include exam-style questions with accompanying mark schemes so that students can assess their understanding, guided discussion periods and quiz competitions to introduce key values and terminology in a memorable way
£9.00
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