This detailed lesson has been written to act as an introduction to gene mutations and the potential effects on the polypeptide chain. The engaging PowerPoint and accompanying resources have been designed to cover point 6.2 (b) and © of the CIE International A-level Biology specification and explores how substitution, insertions and deletions can change the primary structure.
The lesson has been written to tie in with previous lessons where the genetic code was introduced and students will be challenged to describe how the degenerate nature of the code means that a substitution mutation doesn’t always lead to a change in structure. As detailed in point ©, students will learn how a single change to the primary structure of the HBB gene results in abnormal haemoglobin and they are challenged to recall knowledge about the structure and function of haemoglobin whilst completing a detailed passage about sickle cell anaemia. Time is also taken to look at changes to the structure as a result of frameshift mutations and this is related to the non-overlapping code. This topic is met again in topic 16 so this lesson has been designed to act as an introduction before greater detail can be added
Get this resource as part of a bundle and save up to 47%
A bundle is a package of resources grouped together to teach a particular topic, or a series of lessons, in one place.
Bundle
Topics 5 & 6: The mitotic cell cycle, nucleic acids & protein synthesis (CIE A-level Biology)
This lesson bundle contains 12 detailed lesson PowerPoints, which along with their accompanying resources, have been intricately planned to cover the majority of the content of topics 5 and 6 of the CIE A-level Biology specification. The cell cycle, mitosis and protein synthesis are topics that students tend to find difficult and therefore the planning focused on the inclusion of a wide range of tasks that would not only promote the retention of important information and secure knowledge but also maintain motivation and engagement. The tasks include exam-style questions with displayed mark schemes which challenge the students on their current understanding and prior knowledge, guided discussion points and quick quiz competitions which introduce key terms and values. The following specification points are covered by these 12 lessons: Topic 5 * The structure of a chromosome, limited to DNA, histone proteins, chromatids, centromere and telomere * The importance of mitosis in producing genetically identical cells, growth, cell replacement, repair of tissues and asexual reproduction * The cell cycle, including the G and S phases of interphase, mitosis and cytokinesis * Uncontrolled cell division and the formation of tumours * The behaviour of chromosomes in animal and plant cells in the mitotic cell cycle Topic 6 * The structure of nucleotides, including ATP * The structure of DNA and RNA * The semi-conservative replication of DNA during interphase * A polypeptide is coded for by a gene * Gene mutations can cause changes to the polypeptide sequence * The information in DNA is used during transcription and translation to construct polypeptides
£19.00
Bundle
Topic 6: Nucleic acids and protein synthesis (CIE International A-level Biology)
This is a fully-resourced lesson bundle, where the detailed and engaging PowerPoints and accompanying worksheets have been designed to cover the details of topic 6 of the CIE International A-level Biology specification which concerns the nucleic acids and protein synthesis. All 7 of the lessons include differentiated tasks to cater for all abilities of students whilst containing the detail to push them to the next level. The following specification points are covered within these lessons: * The structure of nucleotides * ATP as a phosphorylated nucleotide * The structure of DNA * The structure of mRNA, tRNA and rRNA * DNA replication * Genes and polypeptides * Gene mutations * Sickle cell anaemia * Transcription and translation Links are continually made throughout the lessons to previously-covered topics as well as to those which will be covered later in the AS course or during the second year If you would like to sample the quality of the lessons, download the semi-conservative replication and gene mutation lessons as these have been shared for free
£10.00
Bundle
Topic 6.2: Protein synthesis (CIE International A-level Biology)
Each of the 4 lessons in this bundle are fully-resourced and have been designed to cover the content as detailed in topic 6.2 (Protein synthesis) of the CIE International A-Level Biology specification. The specification points that are covered within these lessons include: * A polypeptide is coded for by a gene * A gene mutation is a change in the sequence of nucleotides * Sickle cell anaemia results from a change in the amino acid sequence * Transcription as the production of mRNA from DNA * Information on DNA is used during translation to construct polypeptides The lessons have been written to include a wide range of activities and numerous understanding and prior knowledge checks so students can assess their progress against the current topic as well as be challenged to make links to other topics within this topic and earlier topics If you would like to see the quality of the lessons, download the introduction to gene mutations lesson as this has been shared for free
£6.00
Bundle
Topics 6.1 & 6.2: Nucleic acids & protein synthesis (CIE International A-level Biology)
Each of the 6 lessons which are included in this bundle have been written to specifically cover the content as detailed in topics 6.1 & 6.2 of the CIE International A-level Biology specification. The wide range of activities will maintain engagement whilst supporting the explanations of the biological knowledge to allow the students to build a deep understanding of nucleic acids and protein synthesis Lessons which cover the following specification points are included in this bundle: * Structure of DNA and RNA * Genes as base sequences that code for polypeptides * Gene mutations * Transcription * Translation If you would like to see the quality of the lessons, download the lesson on gene mutations as this have been uploaded for free
£9.00
Something went wrong, please try again later.
Thank you sooo much
Report this resourceto let us know if it violates our terms and conditions.
Our customer service team will review your report and will be in touch.
£0.00