L5. Antibodies and monoclonal antibodies

This lesson is based on AQA A-level biology specification, looking at the topic of antibodies and monoclonal antibodies. In this lesson students will describe the structure of antibodies and how it relates to its highly specific function. Students will explain the process of monoclonal antibodies and its uses in medicine for diagnostic testing. Worksheets will also allows students to discuss the ethical concerns around the use of monoclonal antibodies. This lesson looks at various applications of monoclonal antibodies, specifically looking at pregnancy test and the ELISA test which will provide great foundation for the topic L7. HIV. Engagement is important, so the lesson begins with a fun starter game called hot seat, this game test students’ knowledge of keywords by applying their prior knowledge as well team building to derive to the correct answer.

This lesson includes the following:

• Interactive and team building starter game
• Worksheets for antibody diagram, ethics of monoclonal antibodies
• Exam questions
• Answers are included for worksheets and mark schemes

Estimated lesson time: 2 hours of A-level teaching