This lesson has been written to cover the 2nd part of specification point 14.1 (f) of the CIE International A-level Biology specification which states that students should be able to describe how the process of selective reabsorption is involved in the formation of urine. It has specifically been designed to build on the knowledge gained in the previous lessons on the structure of the nephron and ultrafiltration. The lesson begins by challenging the students to recall the substances that are found in the glomerular filtrate so that each of them can be considered over the course of the rest of the lesson. Moving forwards, the first of the numerous discussion points which are included in the lesson is used to get students to predict the component of the filtrate which won’t be found in the urine when they are presented with pie charts from each of these situations. Upon learning that glucose is 100% reabsorbed, along with most of the ions and some of the water, the rest of the lesson focuses on describing the relationship between the structure of the PCT and the function of selective reabsorption. Again, this section begins by encouraging the students to discuss and to predict which structures they would expect to find in a section of the kidney if the function is to reabsorb. They are given the chance to see the structure (as shown in the cover image) before each feature is broken down to explain its importance. Time is taken to look at the role of the cotransporter proteins to explain how this allows glucose, along with sodium ions, to be reabsorbed from the lumen of the PCT into the epithelial cells. The final part of the lesson focuses on urea and how the concentration of this substance increases along the tubule as a result of the reabsorption of some of the water. This lesson has been designed for students studying on the CIE International A level Biology course and ties in closely with the other lessons on the kidney

This lesson has been written for GCSE students and aims to ensure that they can explain in detail why light changes direction due to refraction. The key to the explanation is the use of the correct terms in context so the start of the lesson challenges the students to come up with the key words of light, bend, normal, density and speed when given a range of clues. The next part of the lesson works with the students to bring these key terms together to form a definition of refraction. Moving forwards, the relationship between density of a medium and the speed of light through that medium is discussed so that there is a clear understanding of why light bends one way or the other. The next task uses the definition to apply to a practical situation to draw a diagram of light moving from air to glass. The final part of the lesson involves a range of practicals so this topic can be explored further.

A fast-paced lesson which includes an informative lesson presentation (20 slides) and a question worksheet. Together these resources guide GCSE students through the calculation questions that they can encounter on the topic of the conservation of momentum. The lesson begins by introducing the law of the conservation of momentum and reminding students of the equation which links momentum, mass and velocity that they are expected to recall for the GCSE exam. Time is taken to inform them of the two types of question which tend to arise on this topic - those where the masses lock together during the event and those where they remain as separate masses. Students are guided through both of these types of questions with worked examples to enable them to visualise how to begin and set out their workings. Key mathematical skills are involved such as rearranging the formula so this is also shown. Students are given the opportunity to apply these skills to a series of questions on the worksheet and the mark schemes are displayed so they can assess once completed.

An engaging and informative lesson presentation (40 slides) that looks at the different steps that have to be taken when trying to identify potential donors for organ transplants. Links are made throughout the lesson to related topics such as the human defence systems and blood groups. The lesson begins by challenging the students to use their knowledge of the body’s defences to explain why closely matching tissues is critical when choosing a donor. Moving forwards, students will see how the four blood groups in the ABO system need to receive certain bloods and can only be given to certain others. There is a brief discussion of the HLA antigens and why this needs to be matched. The remainder of the lesson focuses on immuno-suppressant drugs and the advantages and disadvantages to individuals of taking these drugs. Progress checks have been written into the lesson at regular intervals to allow the students to constantly assess their understanding and any misconceptions to be addressed. This lesson has been written for GCSE students

An informative lesson that looks at how energy is lost at each stage of a food chain and how this affects the biomass of consumers. This lesson has been written for GCSE students but could be used with A-level students who are revisiting this ecology topic. The lesson begins by posing a question to the students about why herbivores tend to be raised for food rather than carnivores to see how they would tackle it at this early stage. This exact question is revisited at the end of the lesson once learning has occurred so that students can monitor their own progress. Time is taken to look back at pyramids of biomass and food chains so that students are reminded of key terminology such as trophic level and also recognise that the biomass decreases at each level. A number of quick competitions have been written into the lesson to maintain engagement but also to introduce key terms and numbers (like 10%) in a different way. The main part of the lesson looks at how the energy is lost by organisms that leads to the decrease in biomass and links are made to related topics such as respiration and homeostasis.

This lesson describes how enzymes can be immobilised in calcium alginate and compares their activity against enzymes that are free in solution. The PowerPoint and the accompanying resources have been designed to cover point 3.2 (d) of the CIE A-level Biology specification. The lesson has been planned to challenge the students on their ability to apply knowledge to a potentially unfamiliar situation. A series of exam-style questions which include “suggest” and “describe and explain” questions are used throughout the lesson and these will allow the students to recognise the advantages and disadvantages of a particular method. Although the alginate method is the only one referenced in this specification point, the adsorption and covalent bonding methods are introduced and then briefly analysed to allow students to understand that a matrix doesn’t involve these bonds which could disrupt the active site. The remainder of the lesson introduces some actual examples of the use of immobilised enzymes with the aim of increasing the relevance. Please note that this lesson has been written to explain the effect of immobilisation on enzyme activity. The practical element of carrying out the investigation is described in a separate lesson.

This engaging revision resource has been written with the sole aim of challenging students on their knowledge of both the Core and Supplement sections of TOPIC 2 of the Cambridge IGCSE Physics specification. The resource includes an engaging PowerPoint (68 slides) and accompanying worksheets, some of which are differentiated. The wide range of activities in the lesson which include exam questions with explained answers and quiz competitions will motivate the students whilst they evaluate and assess their knowledge of the content and recognise those areas which will require further attention. The lesson has been designed to cover as many parts of the topic as possible, but the following sub-topics have been given a particular focus: The properties of solids, liquids and gases Conduction, convection and radiation Melting and boiling points Boiling vs evaporation Specific latent heat The structure and action of liquid-in-glass thermometers The use of thermocouples Specific heat capacity The mathematical elements of the topic are covered throughout the lesson and students are given helpful hints to support them in structuring their answers. This resource can be used at the end of the topic or in the lead up to the mocks or the actual IGCSE terminal examinations.

This fully-resourced lesson looks at the details of glycolysis as the first stage of respiration and explains how the sequence of reactions results in glucose being converted to pyruvate. The engaging PowerPoint and accompanying differentiated resources have been designed to cover point 12.2 (b) of the CIE International A-level Biology specification which states that students should know glycolysis as the phosphorylation of glucose and the subsequent splitting into triose phosphate which is then oxidised to pyruvate. The lesson begins with the introduction of the name of the stage and then explains how the phosphorylation of the hexoses and the production of the ATP, coenzymes and pyruvate are the stages that need to be known for this specification. Time is taken to go through each of these stages and key points such as the use of ATP in phosphorylation are explained so that students can understand how this affects the net yield. A quick quiz competition is used to introduce NAD and the students will learn that the reduction of this coenzyme, which is followed by the transport of the protons and electrons to the cristae for the electron transport chain is critical for the overall production of ATP. Understanding checks, in a range of forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed.

This fully-resourced REVISION lesson has been written to challenge the students on their knowledge of the content of topic 1 (Cell structure) of the CIE International A-level Biology specification. The PowerPoint and accompanying resources will motivate the students whilst they assess their understanding of the content and identify any areas which may require further attention. The wide range of activities have been written to cover as much of the topic as possible but the following specification points have been given particular focus: ATP is produced in mitochondria and chloroplasts and the role of ATP in cells Recognising eukaryotic cell structures and outlining their functions Calculating actual sizes from electron micrographs The structural features of a typical prokaryotic cell The key features of viruses as non-cellular structures Distinguish between resolution and magnification Quiz rounds such as “GUESS WHO of CELL STRUCTURES” and “YOU DO THE MATH” are used to test the students on the finer details of their knowledge of the structure and functions of the organelles and some key numerical facts

This lesson describes the classification of species into the taxonomic hierarchy and cover point 18.2 (a) of the CIE A-level Biology specification. The engaging PowerPoint and accompanying resources have been designed to show students how the domain, kingdom, phylum, class, order, family, genus and species are used in modern-day classification. The lesson begins by with a knowledge recall as students have to use the provided information about a mule to explain why a horse and donkey are considered to be members of different species. Moving forwards, students will learn that species is the lowest taxon in the modern-day classification hierarchy. The first of a number of rounds of a competition is used to engage the students whilst they learn the names of the 7 other taxa and the horse and the donkey from the earlier example are used to complete the hierarchy. Students are told that a binomial naming system is used in Biology to provide a universal name for each species and the final task of the lesson challenges them to apply their knowledge by completing a hierarchy for a modern-day human, by spotting the correct name for an unfamiliar organism

This lesson has been written to act as a revision tool for students at the completion of topic 2.1 of the WJEC GCSE Physics specification or in the lead up to mock or terminal exams. The engaging PowerPoint and accompanying resources have been designed to include a wide range of activities to allow the students to assess their understanding and to recognise any areas which need extra attention. This specification is heavy in mathematical content and so a lot of opportunities are presented for a range of skills to be tested and the PowerPoint guides students through the application of these requirements such as rearranging the formula and converting between units. The following specification points have received a particular focus in this lesson: Motion using speed, velocity and acceleration Speed-time graphs Application of the equations to calculate speed and acceleration Using velocity-time graphs to calculate uniform acceleration and distance travelled Knowledge of the terms reaction time, thinking distance, braking distance and stopping distance The factors which affect these distances A number of quick quiz rounds, such as THE WHOLE DISTANCE, are used to maintain engagement and motivation and to challenge the students on their recall of important points.

This lesson explains the importance of memory cells in the development of immunity and describes how the structure of antibodies is related to function. The PowerPoint and accompanying resources have been designed to cover specification points 11.1 (e) and 11.2 (a) as detailed in the CIE A-level Biology specification. As memory B cells differentiate into plasma cells that produce antibodies when a specific antigen is re-encountered, it was decided to link these two topic points in one lesson. The lesson begins by checking on the students incoming knowledge to ensure that they recognise that B cells differentiate into plasma cells and memory cells. This was introduced in a previous lesson on the specific immune response and students must be confident in their understanding if the development of immunity is to be understood. A couple of quick quiz competitions are then used to introduce key terms so that the structure of antibodies in terms of polypeptide chains, variable and constant regions and hinge regions are met. Time is taken to focus on the variable region and to explain how the specificity of this for a particular antigen allows neutralisation and agglutination to take place. The remainder of the lesson focuses on the differences between the primary and secondary immune responses and a series of exam-style questions will enable students to understand that the quicker production of a greater concentration of these antibodies in the secondary response is due to the retention of memory cells.

This revision resource includes exam questions, understanding checks and quiz competitions, all of which have been designed with the aim of motivating and engaging the students whilst they assess their understanding of the content found in topic 5 (Enzymes) of the CIE IGCSE Biology specification for examination in June and November 2020 and 2021. This revision resource contains an engaging PowerPoint (25 slides) and associated worksheet. The range of activities have been designed to cover as much of the Core and supplement content as possible but the following sub-topics have been given particular attention: Define enzymes as proteins that function as biological catalysts Explain enzyme action with reference to active site, substrate and enzyme-substrate complex Explain the specificity of enzymes Explain the effect of changes of temperature on enzyme activity Explain the effect of changes of pH on enzyme activity Describe what happens to an enzyme when it is denatured

This clear and concise lesson looks at the calculation of cardiac output as the product of stroke volume and heart rate. This engaging PowerPoint and accompanying resource have both been designed to cover point 7.9 (i) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification which states that students should be able to calculate cardiac output. The lesson begins by challenging the students to recall that the left ventricle is the heart chamber with the thickest myocardial wall. This leads into the introduction of stroke volume as the volume of blood which is pumped out of the left ventricle each heart beat. A quick quiz game is used to introduce a normative value for the stroke volume and students are encouraged to discuss whether males or females would have higher values and to explain why. A second edition of this quiz reveals a normative value for resting heart rate and this results into the introduction of the equation to calculate cardiac output. A series of questions are used to challenge their ability to apply this equation and percentage change is involved as well. The final part of the lesson looks at the hypertrophy of cardiac muscle and students will look at how this increase in the size of cardiac muscle affects the three factors and will be challenged to explain why with reference to the cardiac cycle that was covered in an earlier topic.

Alongside the “properties of waves” lesson, this lesson is also designed to be fast-paced with a focus on the key terminology of the waves topic as well as looking at the different calculations that can be carried out. It is written for GCSE students and challenges their mathematical skills throughout, by asking them to rearrange formulae, convert units and write in standard form. The lesson begins by recalling the definitions for wavelength, frequency and wave velocity and then introducing them to the equation that links them. The velocity of sound waves in three mediums is the initial focus, so that students can recognise that the velocity is higher in liquids and solids than in air. Moving forwards, the concept of an echo is discussed and again a calculation used to show them how distance could be worked out with the added extra of the final division by 2. There are progress checks such as these written throughout the lesson so that students have the opportunity to assess their understanding. A number of quick competitions are also included, in order to maintain engagement whilst check understanding in a different form.

This concise, fully-resourced lesson covers the content of specification point 15.1 (i) of the CIE International A-level Biology specification which states that students should be able to describe the roles of the neuromuscular junction, transverse tubules and sarcoplasmic reticulum in the stimulation of the contraction of striated muscle. Due to a number of similarities between these structures and cholinergic synapses, this lesson uses prior knowledge of these connections between neurones to build a good understanding of the junctions. Students will discover that the events that occur at an axon tip mirror those which happen at the pre-synaptic bulb and this is then developed to look at the differences in terms of the events once the acetylcholine has bound to its receptor sites. There is a focus on the structure of the sarcolemma and time is taken to explain how the action potential is passed from this membrane to the transverse tubules in order to stimulate the release of calcium ions from the sarcoplasmic reticulum. As a result, this lesson ties in nicely with the following lesson on the contraction of skeletal muscle and students will be able to link the binding to troponin in that lesson to the release of these ions from this lesson. Both of the main tasks of the lesson have been differentiated so that students of all abilities can access the work and make progress. This lesson has been designed for those students studying on the CIE International A-level Biology course and ties in well with the other uploaded lessons on topic 15.1 (Control and coordination in mammals)

This detailed lesson has been written to cover the 1st part of specification point 14.1 (f) of the CIE International A-level Biology specification which states that students should be able to describe how the process of ultrafiltration is involved with the formation of urine. The aim of the design was to give the students the opportunity to discover this particular function and to be able to explain how the mechanisms found in the glomerulus and the Bowman’s capsule control the movement of small molecules out of the blood plasma. Key terminology is used throughout and students will learn how the combination of the capillary endothelium and the podocytes creates filtration slits that allow glucose, water, urea and ions through into the Bowman’s capsule but ensure that blood cells and plasma proteins remain in the bloodstream. A number of quiz competitions are used to introduce key terms and values in a fun and memorable way whilst understanding and prior knowledge checks allow the students to assess their understanding of the current topic and to challenge themselves to make links to earlier topics. The final task of the lesson challenges the students to apply their knowledge by recognising substances found in a urine sample that shouldn’t be present and to explain why this would cause a problem This lesson has been written for students studying on the CIE International A-level Biology course and ties in closely with the other kidney lessons on the structure of the nephron, selective reabsorption and osmoregulation

This concise and engaging lesson has been designed to cover specification point 15.1 (j) of the CIE International A-level Biology specification which states that students should be able to describe the ultrastructure of striated muscle with particular reference to sarcomere structure. The wide range of key terms and regions are introduced in a fun and memorable way using a variety of activities that include quiz competitions and then understanding checks are used throughout to assess their progress and ensure that any misconceptions are addressed. Connections are made to the upcoming topic of the sliding filament model as the students discover that despite the shortening of the sarcomere (and I band and H zone) during contraction, the fact that the A band remains the same length shows how the filaments slide over each other. The two main tasks of the lesson challenge the students to label a diagram of a sarcomere and then the microscope image as shown in the cover picture. This lesson has been designed to tie in well with the other uploaded lessons that cover the content of topic 15.1 of the CIE International A-level Biology course which is the control and coordination in mammals

This lesson describes how to calculate the cardiac output as the product of stroke volume and the heart rate. The PowerPoint and accompanying resource have been designed to cover point 7.13 (i) of the Edexcel International A-level Biology specification. The lesson begins by challenging the students to recognise that the left ventricle has the most muscular wall of all of the heart chambers. This allows the stroke volume to be introduced as the volume of blood ejected from the left ventricle each heart beat and then a quiz competition is used to introduce normative values for the stroke volume and the heart rate. Moving forwards, students will learn that the cardiac output is the product of the stroke volume and the heart rate. A series of exam-style questions will challenge the students to use this formula and to manipulate it and to work out the percentage change. The final part of the lesson looks at the adaptation of the heart to aerobic training in the form of cardiac hypertrophy and then the students are challenged to work out how this would affect the stroke volume, the cardiac output and the resting heart rate.

This lesson explains the principles of the polymerase chain reaction (PCR) and the PowerPoint has been designed to cover point 6.1.3 (d) of the OCR A-level Biology A specification A quick quiz competition is used to introduce the PCR abbreviation before students are encouraged to discuss the possible identity of the enzyme involved and to recall the action of this enzyme. Students will learn that this reaction involves cyclical heating and cooling to a range of temperatures so the next part of this lesson focuses on each temperature and specifically the reasons behind the choice. Time is taken to examine the key points in detail, such as why Taq polymerase has to be used as it is not denatured at the high temperature as well as the involvement of the primers. This process is closely linked to other techniques like electrophoresis which is covered in a later lesson and ties are continuously made throughout the lesson This process is mentioned in other uploaded lessons in this module such as electrophoresis and genetic engineering to allow students to understand how it is critical for DNA analysis