pptx, 2.64 MB
pptx, 2.64 MB
docx, 13.4 KB
docx, 13.4 KB
pptx, 43.3 KB
pptx, 43.3 KB
pptx, 45.14 KB
pptx, 45.14 KB
docx, 14.7 KB
docx, 14.7 KB
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docx, 16.7 KB
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docx, 20 KB

This fully-resourced lesson describes the roles of the platelets and plasma proteins in the sequence of events that lead to blood clotting. The engaging PowerPoint and accompanying resources have been primarily designed to cover the content detailed in point 4.4 (viii) of the Edexcel A-level Biology B specification and includes descriptions of the roles of thromboplastin, thrombin and fibrin but time has also been taken to look at haemophilia as a sex-linked disease so that students are prepared for topic 8 (genetic variation).

The lesson begins with the introduction of clotting factors as integral parts of the blood clotting process and explains that factor III, thromboplastin, needs to be recalled as well as the events that immediately precede and follows its release. Students will learn how damage to the lining and the exposure of collagen triggers the release of this factor and how a cascade of events then results. Quick quiz rounds and tasks are used to introduce the names of the other substances involved which are prothrombin, thrombin, fibrinogen and fibrin. In a link to the upcoming topic of proteins, students will understand how the insolubility of fibrin enables this mesh of fibres to trap platelets and red blood cells and to form the permanent clot.

The final part of the lesson introduces haemophilia as a sex-linked disease and students are challenged to apply their knowledge to an unfamiliar situation as they have to write genotypes and determine phenotypes before explaining why men are more likely to suffer from this disease than women.

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Topic 4: Exchange and transport (Edexcel A-level Biology B)

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Topic 4.4: Circulation (Edexcel A-level Biology B)

The 5 lesson PowerPoints and multiple accompanying resources that are included in this bundle are highly-detailed and engaging. A wide variety of tasks, which include exam-style questions, differentiated tasks, discussion points and quiz competitions will check on the student understanding of the following specification points in topic 4.4 of the Edexcel A-level Biology B specification: * The structure of the heart, arteries, veins and capillaries * The advantages of a double circulatory system * The sequence of events of the cardiac cycle * The roles of the SAN, AVN and the bundle of His in the myogenic stimulation of the heart * Interpreting ECG traces and pressure changes in the cardiac cycle * The role of platelets and plasma proteins in the sequence of events leading to blood clotting The heart & blood vessels and the double circulatory system lesson have been uploaded for free so you can sample the quality of this bundle by downloading those

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