This lesson explains how to calculate the mitotic index and then explores what a high value may indicate about the tissue that was sampled. The PowerPoint and accompanying resources are part of the 2nd lesson in a series of 3 which have been planned to cover the content of point 2.2 of the AQA A-level biology specification.
As shown in the cover image, the lesson begins with a bit of fun, as the students are challenged to use three clues to identify three uses of the term index in biology. They’ll learn that the index of diversity is covered in a topic 4 lesson and that this lesson focuses on the mitotic index. The students are challenged on their knowledge of the mitotic cell cycle throughout the lesson and one of these questions is used to introduce the meaning of the index and the formula. A series of exam-style questions challenge them to apply their understanding, and the answers are embedded into the PowerPoint to enable the students to assess their progress. Moving forwards, the different meanings of high values are considered, including growing and repairing tissues, and then to explain how an elevated mitotic index can indicate that cell division has become uncontrolled. This prepares students for the next lesson where tumour formation and cancer will be covered.
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Both lessons in this bundle are detailed and engaging and use regular understanding checks (with answers embedded into the PowerPoints) to enable the students to assess their progress. The lessons have been planned to cover these points from topic 2.2 of the AQA A-level biology specification: * Eukaryotic cells show a cell cycle * DNA replication occurs during interphase of the cell cycle * Mitosis is part of the cell cycle * The behaviour of chromosomes in interphase, prophase, metaphase, anaphase and telophase * Division of the cytoplasm during cytokinesis produces two new cells * Calculation of the mitotic index
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