A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
This lesson describes how respiration produces ATP by substrate-level and oxidative phosphorylation. The PowerPoint and accompanying resources are part of the 1st lesson in a series of 7 lessons which have been designed to cover the detailed content of point 5.2 (RESPIRATION) of the AQA A-level Biology specification.
As the first lesson in this sub-topic, it has been specifically planned to act as an introduction to this cellular reaction and provides important details about glycolysis, the Krebs cycle and oxidative phosphorylation that will support the students to make significant progress when these stages are covered during individual lessons. Students met phosphorylation in topic 5.1 when considering the light-dependent reactions of photosynthesis and their knowledge of the production of ATP in this plant cell reaction is called on a lot in this lesson to show the similarities. The students are also tested on their recall of the structure and function of ATP, as covered in topic 1.6, through a spot the errors task. By the end of the lesson, the students will be able to name and describe the different types of phosphorylation and will know that ATP is produced by substrate-level phosphorylation in glycolysis and the Krebs cycle and by oxidative phosphorylation in the final stage of aerobic respiration with the same name.
This is a highly engaging and detailed lesson which looks at the physiological and behavioural responses involved in temperature control in endotherms and therefore covers specification point 5.1.1 (d) of the OCR A-level Biology A specification. A wide range of activities have been written into the PowerPoint and accompanying worksheets so that students remain motivated throughout and take a genuine interest in the content. Understanding checks allow the students to assess their progress whilst the prior knowledge checks on topics such as enzymes and denaturation demonstrate the importance of being able to make connections and links between topics from across the specification. In addition to these checks, quiz competitions like HAVE an EFFECT which is shown in the cover image are used to introduce key terms and values in a fun and memorable way.
The lesson begins by introducing the key term, endotherm, and challenging students to use their prior knowledge and understanding of terminology to suggest what this reveals about an organism. Moving forwards, students will learn how the heat generated by metabolic reactions is used as a source of internal heat. The main part of the lesson focuses on thermoregulation in humans (mammals) and time is taken to focus on the key components, namely the sensory receptors, the thermoregulatory centre in the hypothalamus and the responses brought about by the skin. The important details of why the transfer of heat energy between the body and the environment actually leads to a decrease in temperature are explored and discussed at length to ensure understanding is complete. Students are challenged to write a detailed description of how the body detects and responds to a fall in body temperature and this task is differentiated for those students who need some extra assistance. The peripheral thermoreceptors are introduced and this leads into the final section of the lesson that considers behavioural responses in humans and other animals.
This lesson has been designed for A-level students studying the OCR A-level Biology A course
This lesson focuses on the degenerate nature of the genetic code and explains how a mutation may not result in a change to the sequence of amino acids. The PowerPoint has been designed to cover the first part of point 4.3 of the AQA A-level Biology specification and it makes links to the upcoming lesson on gene mutations.
The lesson begins by introducing the terms near universal and non-overlapping in addition to degenerate. A quick quiz competition is used to generate the number 20 so that the students can learn that there are 20 proteinogenic amino acids in the genetic code. This leads into a challenge, where they have to use their prior knowledge of DNA to calculate the number of different DNA triplets (64) and the mismatch in number is then discussed and related back to the lesson topic. Moving forwards, base substitutions and base deletions are briefly introduced so that they can see how although one substitution can change the primary structure, another will change the codon but not the encoded amino acid. The lesson concludes with a brief look at the non-overlapping nature of the code so that the impact of a base deletion (or insertion) can be understood when covered in greater detail in topic 8.
This lesson has been specifically designed to tie in with the other lessons from topic 4.3 on gene mutations, chromosome mutations and meiosis.
This fully-resourced lesson explores how other respiratory substrates, such as lipids and proteins, can be used to produce molecules of ATP. The PowerPoint and accompanying resources have been designed to cover the 7th and final part of point 5.2 of the AQA A-level Biology specification which states that students should know how these substrates enter the Krebs cycle.
This lesson has been written to challenge the knowledge of the earlier parts of the topic of respiration and so contains constant prior knowledge checks which come in a range of forms. Students will learn that lipids and proteins can be used as respiratory substrates and will recognise the different ways that they enter the respiratory pathway. Time is taken to look at the beta oxidation pathway and again students are challenged to compare the products of this pathway against that of the Link reaction.
This detailed lesson looks at the structure of the mitochondrion and explains how the specific features allow the stages of aerobic respiration to take place in this organelle. The engaging PowerPoint and accompanying resource have been designed to cover point 5.2.2 (b) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the inner and outer mitochondrial membranes, cristae, matrix and mitochondrial DNA.
The lesson begins with a version of “GUESS WHO” where students have to use a series of structural clues to whittle the 6 organelles down to just 1 - the mitochondrion. Moving forwards, the key components of the organelle are identified on a diagram. Students are introduced to the stages of respiration so that they can make a link to the parts of the cell and the mitochondria where each stage occurs. Students will learn that the presence of decarboxylase and dehydrogenase enzymes in the matrix along with coenzymes and oxaloacetate allows the Link reaction and the Krebs cycle to run. Finally, time is taken to introduce the electron transport chain and the enzyme, ATP synthase, so that students can begin to understand how the flow of protons across the inner membrane results in the production of ATP.
This lesson has been designed to tie in with the other uploaded lessons on the stages of respiration.
This clear and concise lesson explores the importance of coenzymes in cellular respiration as detailed in point 5.2.2 (f) of the OCR A-level Biology A specification.
Students encountered coenzymes in module 2.1.4 as well as looking at the roles of NAD, CoA and FAD whilst learning about glycolysis, the link reaction and Krebs cycle earlier in this module. Therefore this lesson was designed to check on their understanding of the importance of these roles and goes on to explain how the transport of the protons and electrons to the mitochondrial cristae is key for the production of ATP.
This lesson has been written to tie in with the other uploaded lessons in module 5.2.2 which include the mitochondria, glycolysis, the link reaction and the Krebs cycle
This fully-resourced lesson looks at the series of oxidation-reduction reactions that form the Krebs cycle and focuses on the products in terms of reduced NAD, FAD and ATP. The engaging PowerPoint and accompanying resource have both been designed to cover the fifth part of point 5.2 of the AQA A-level Biology specification.
The lesson begins with a version of the Impossible game where students have to spot the connection between 8 of the 9 terms and will ultimately learn that this next stage is called the Krebs cycle. The main part of the lesson challenges the students to use descriptions of the main steps of the cycle to continue their diagram of the reactions. Students are continually exposed to key terminology such as decarboxylation and dehydrogenation and they will learn where carbon dioxide is lost and reduced NAD and FAD are generated. They will also recognise that ATP is synthesised by substrate level phosphorylation. The final task challenges them to apply their knowledge of the cycle to work out the numbers of the different products and to calculate the number of ATP that must be produced in the next stage
This lesson has been designed to tie in with the other uploaded lessons on glycolysis, anaerobic respiration, the Link reaction and oxidative phosphorylation.
This clear and concise lesson looks at the role of the Link reaction in the conversion of pyruvate to acetyl coenzyme A which will then enter the Krebs cycle. The PowerPoint has been designed to cover the fourth part of point 5.2 of the AQA A-level Biology specification which states that students should know about this conversion and the production of reduced NAD
The lesson begins with a challenge, where the students have to recall the details of glycolysis in order to form the word matrix. This introduces the key point that this stage occurs in this part of the mitochondria and time is taken to explain why the reactions occur in the matrix as opposed to the cytoplasm like glycolysis. Moving forwards, the Link reaction is covered in 5 detailed bullet points and students have to add the key information to these points using their prior knowledge as well as knowledge provided in terms of NAD. The students will recognise that this reaction occurs twice per molecule of glucose and a quick quiz competition is used to test their understanding of the numbers of the different products of this stage. This is just one of the range of methods that are used to check understanding and all answers are explained to allow students to assess their progress.
This lesson has been written to tie in with the other uploaded lessons on glycolysis and the Krebs cycle and oxidative phosphorylation.
This lesson describes and explains how increasing the concentration of inhibitors affects the rate of an enzyme-controlled reaction. The PowerPoint and accompanying resource are the last in a series of 5 lessons which cover the content detailed in point 1.4.2 of the AQA A-level Biology specification and describes the effect of both competitive and non-competitive inhibitors.
The lesson begins with a made up round of the quiz show POINTLESS called “Biology opposites” and this will get the students to recognise that inhibition is the opposite of stimulation. This introduces inhibitors as substances that reduce the rate of a reaction and students are challenged to use their general knowledge of enzymes to identify that inhibitors prevent the formation of the enzyme-substrate complex. Moving forwards, a quick quiz competition generates the abbreviation EIC (representing enzyme-inhibitor complex) and this introduces competitive inhibitors as substances that occupy the active site. The students are asked to apply their knowledge to a new situation to work out that these inhibitors have a similar shape to the enzyme’s substrate molecule. A series of exam-style questions are used throughout the lesson and at this point, the students are challenged to work out that an increase in the substrate concentration would reduce the effect of a fixed concentration of a reversible competitive inhibitor. The rest of the lesson focuses on non-competitive inhibitors and time is taken to ensure that key details such as the disruption of the tertiary structure is understood and biological examples are used to increase the relevance. Again, students will learn that increasing the concentration of the inhibitor results in a greater inhibition and a reduced rate of reaction but that increasing the substrate concentration cannot reduce the effect as was observed with competitive inhibitors.
Adenosine triphosphate is the universal energy currency and this lesson focuses on the structure of this nucleotide derivative. The PowerPoint has been designed to cover point 1.6 of the AQA A-level Biology specification and also explains how ATP must be hydrolysed to release energy and then re-synthesised during respiration and photosynthesis.
As the previous sub-topic concerned the structure of DNA and RNA, the start of this lesson challenges the students on their knowledge of these polynucleotides so that they can recognise that this molecule consists of adenine, ribose and three phosphate groups. In order to release the stored energy, ATP must be broken down and students will be given time to discuss which reaction will be involved as well as the products of this reaction. Time is taken to describe how the hydrolysis of ATP can be coupled to energy-requiring reactions within cells and the examples of active transport and skeletal muscle contraction are used as these are covered in greater detail in topic 2 and 6. The final part of the lesson considers how ATP must be re-synthesised and students will learn that this occurs in the mitochondria and chloroplast during aerobic respiration and photosynthesis respectively.
This engaging lesson describes how the structure of the phloem enables this vascular tissue to transport organic substances in plants. Both the detailed PowerPoint and accompanying resource have been designed to cover the 3rd part of point 3.4.2 (Mass transport in plants) of the AQA A-level Biology specification.
Comparative questions between the xylem and phloem are very common so the lesson begins by challenging the students to use their prior knowledge to complete the xylem column of a table with details including the presence of lignin and bordered pits and specific substances which are transported in this tissue. This has been written into the lesson to encourage the students to start to think about how the structure and function of the phloem may compare. 3 quiz rounds have been included in the lesson to maintain motivation and to introduce key terms. The first of these rounds will challenge the students to be the first to recognise descriptions of sucrose and amino acids as they learn that these are the two most common assimilate, which are the substances transported by the phloem. The focus of this lesson is the relationship between structure and function and all descriptions have these two parts highlighted to support the students to recognise the link. Moving forwards, students will be introduced to the sieve tube elements and the companion cells and time is taken to consider why the structure of these cells are so different. Current understanding checks are interspersed throughout the lesson to ensure that any misconceptions can be quickly addressed. The plasmodesmata is described to allow students to understand how assimilates move from the companion cells to the sieve tube elements as this will be particularly important for the next lesson on translocation. The final task of the lesson challenges the students to write a detailed passage about the structure and function of the phloem, incorporating all of the information that they have absorbed throughout the course of the lesson.
This fully-resourced lesson describes how enzyme and substrate concentration can affect the rate of an enzyme-controlled reaction. The PowerPoint and accompanying resources are the 4th in a series of 5 lessons which cover the detail of point 1.4.2 of the AQA A-level Biology specification. Transcription and translation are also introduced and therefore this lesson could be used in preparation for the detailed lessons in topic 4.2.
The first part of the lesson describes how an increase in substrate concentration will affect the rate of reaction when a fixed concentration of enzyme is used. Time is taken to introduce limiting factors and students will be challenged to identify substrate concentration as the limiting factor before the maximum rate is achieved and then they are given discussion time to identify the possible factors after this point. A series of exam-style questions are used throughout the lesson and the mark schemes are displayed to allow the students to assess their understanding and for any misconceptions to be immediately addressed. Moving forwards, the students have to use their knowledge of substrate concentration to construct a graph to represent the relationship between enzyme concentration and rate of reaction and they have to explain the different sections of the graph and identify the limiting factors.
The final section of the lesson describes how the availability of enzymes is controlled in living organisms. Students will recognise that this availability is the result of enzyme synthesis and enzyme degradation and a number of prior knowledge checks challenge students on their knowledge of proteins as covered in topic 1.4.1
Please note that this lesson explains the Biology behind the effect of concentration on enzyme-controlled reactions and not the methodology involved in carrying out such an investigation as this is covered in a core practical lesson.
This lesson describes and explains how increasing the temperature affects the rate of an enzyme-controlled reaction. The PowerPoint and the accompanying resource have been designed to cover the second part of point 1.4.2 of the AQA A-level Biology specification and ties in directly with the previous lesson on the properties of enzymes and their mechanism of action.
The lesson begins by challenging the students to recognise optimum as a key term from its 6 synonyms that are shown on the board. Time is taken to ensure that the students understand that the optimum temperature is the temperature at which the most enzyme-product complexes are produced per second and therefore the temperature at which the rate of an enzyme-controlled reaction works at its maximum. The optimum temperatures of DNA polymerase in humans and in a thermophilic bacteria and RUBISCO in a tomato plant are used to demonstrate how different enzymes have different optimum temperatures and the roles of the latter two in the PCR and photosynthesis are briefly described to prepare students for these future lessons.
Moving forwards, the rest of the lesson focuses on enzyme activity at temperatures below the optimum and at temperatures above the optimum. Students will understand that increasing the temperature increases the kinetic energy of the enzyme and substrate molecules, and this increases the likelihood of successful collisions and the production of enzyme-substrate and enzyme-product complexes. When considering the effect of increasing the temperature above the optimum, continual references are made to the previous lesson and the control of the shape of the active site by the tertiary structure. Students will be able to describe how the hydrogen and ionic bonds in the tertiary structure are broken by the vibrations associated with higher temperatures and result in an active site that is no longer complementary to the substrate. Key terminology such as denaturation is used throughout.
Please note that this lesson has been designed specifically to explain the relationship between the change in temperature and the rate of reaction and not the practical skills that would be covered in a core practical lesson
This fully-resourced lesson describes how the different properties of water make this biological molecule incredibly important in Biology. The engaging PowerPoint and accompanying worksheets have been designed to cover point 1.7 of the AQA A-level Biology specification.
Hydrolysis reactions have been a recurring theme throughout topic 1, so the start of this lesson challenges the students to recognise the definition when only a single word is shown: water. Students will also recall the meaning of a condensation reaction. Moving forwards, the rest of the lesson focuses on the relationship between the structure and properties of water, beginning with its role as an important solvent. The lesson has been specifically written to make links to future topics and this is exemplified by the transport of water along the xylem in plants. A quick quiz round is used to introduce cohesion and tension so students can understand how the column of water is able to move along this vascular tissue without interruption. The next section focuses on the high latent heat of vaporisation and heat capacity of water and these properties are put into biological context using thermoregulation and the maintenance of a stable environment for aquatic animals. The lesson finishes with an explanation of the polar nature of water, a particularly important property that needs to be well understood for a number of upcoming topics, such as cell membranes.
Disaccharides are formed from the condensation of two monosaccharides and this lesson describes the formation of maltose, sucrose and lactose. The PowerPoint and accompanying question sheet have been designed to cover the second part of point 1.2 of the AQA A-level Biology specification but also make links to the previous lesson on monosaccharides when considering the different components of these three disaccharides.
The first section of the lesson focuses on a prefix and a suffix so that the students can recognise that the names of the common disaccharides end in -ose. In line with this, a quick quiz round is used to introduce maltose, sucrose and lactose before students are challenged on their prior knowledge as they have to describe how condensation reactions and the formation of glycosidic bonds were involved in the synthesis of each one. The main task of the lesson again challenges the students to recall details of a previous lesson as they have to identify the monomers of each disaccharide when presented with the displayed formula. Time is taken to show how their knowledge of these simple sugars will be important in later topics such as digestion, translocation in the phloem and the Lac Operon in the control of gene expression. The lesson finishes with two exam-style questions where students have to demonstrate and apply their newly acquired knowledge
This revision resource includes exam questions, understanding checks and quiz competitions, all of which have been designed with the aim of motivating and engaging the students whilst they assess their understanding of the content found in topic 10 (Diseases and immunity) of the CIE IGCSE Biology specification for examination in June and November 2020 and 2021. This revision resource contains an engaging PowerPoint (37 slides) and associated worksheets, some of which have been differentiated to help and challenge differing abilities.
The range of activities have been designed to cover as much of the Core and Supplement content as possible but the following sub-topics have been given particular attention:
Pathogens as disease causing microorganisms that cause transmissible diseases when they are spread
Pathogens can be spread through direct or indirect contact
Vaccinations as a form of active immunity that leads to the production of memory cells
Examples of passive immunity
The human body’s defence systems to include the white blood cells
Diabetes type I as an example of an autoimmune disease
A fun and engaging lesson presentation (90 slides) and associated worksheets that uses exam questions, quick tasks and quiz competitions to allow students to assess their understanding of the topic of transport in plants, which is module 3.1.3 on the OCR A-Level Biology A specification. Competition rounds include “Keyword BINGO”, “Crack the Code” and “Make the Link” and students will enjoy being able to identify areas that require further attention. All exam questions have mark schemes.
This lesson is designed for A-level students
This lesson looks at the two stages of protein synthesis, transcription and translation, and focuses on the key details that students need to understand this potentially difficult topic. The lesson presentation has been deliberately written in a concise way to encourage the students to summarise the two stages and pick out the key points which will enable them to form longer answers when necessary. The lesson begins by introducing the students to RNA, and a quick check is done to see how much they can recall about the other nucleic acid, DNA. Moving forwards, students are challenged to study the structure of DNA and RNA in SPOT THE DIFFERENCE before being challenged to explain why RNA is necessary in this process. Time is taken to look at important sections such as complimentary base pairing and the identification of amino acids from the codon. A number of quick competitions have been written into the lesson to maintain engagement and the progress checks are regular so that students assess their understanding and any misconceptions can be quickly identified and addressed.
This lesson has been written for GCSE students but should a teacher want to teach an introduction lesson on protein synthesis before going into more detail at a later date, then this would be suitable.
A thought-provoking lesson presentation (34 slides) that looks at each of the stages in the development of drugs and considers the potential issues that arise at each of the stages.
The lesson begins by ensuring that the students know the scientific definition of a drug and then they will be told how much is spent by the NHS alone each year on medicinal drugs so they can recognise the importance of this topic. Moving forwards, each stage in the development is considered in the appropriate detail. Students are challenged to consider some stages from both a scientific angle and a business angle so they can understand why certain animals are chosen for the testing. Key terms such as placebo and double blind trial are introduced and discussion time is written into the lesson so that insightful questions can be posed by all. There are regular progress checks throughout the lesson to allow the students to check on their understanding.
This lesson has been written for GCSE students but could be used with KS3 students who might be carrying out research or a project on the topic of drugs.
