A thought-provoking and discussion-based lesson which looks at the different ways that biodiversity is being lost across the World. This lesson has been designed for GCSE students and includes a detailed lesson presentation (31 slides) and accompanying worksheet. The lesson begins by challenging the students to use their Biological knowledge to get to a quantitative answer, which is 80%, and then getting them to consider where this much biodiversity would be found around the World. The rainforest plays a key role in the lesson as important discussion topics such as deforestation can easily be related to this area. A range of tasks and discussion points are used to look at the different ways that humans are causing a loss in biodiversity. As well as deforestation, agriculture and eutrophication are explored and related back to the Science. This can be a word heavy topic and therefore a number of quick quiz competitions have been written into the lesson to maintain engagement and energy levels. In addition, progress checks are involved at regular points, including those which challenge mathematical skills in manipulating data. This allows students to constantly assess their understanding.

A fully-resourced lesson, which has been designed for GCSE students, and includes an engaging and informative lesson presentation (37 slides) and differentiated worksheets. This lesson explores the type of cell division known as meiosis and focuses on the use of key terminology so that students can apply their knowledge to any organism that carries out this division, and not just humans. For this reason, time is taken at the start of the lesson to go over the meaning of the terms, diploid and haploid. Students are also taught how to think about the quantity of DNA inside a cell in terms of n, so that they can see and understand how this quantity changes through the cell cycle. They are encouraged to fill in a table at each stage of the cycle to show the quantity of DNA. In this way, students will understand how a diploid parent cell goes through interphase and as a result of DNA replication, the quantity of DNA is 4n as the first meiosis division is about to start. Although this could be viewed as high end knowledge, the format of this lesson should allow all abilities to understand and therefore have more chance of being successful with meiosis questions. Students are encouraged to think for themselves to work out how many daughter cells will result at the end of two divisions and to consider the quantity of DNA found inside those cells. At this stage of the lesson, students have to summarise all they have learnt into two key points (as shown on the cover image). The remainder of the lesson gives them the opportunity to apply their knowledge with a range of questions and it is not until right at the end that they are allowed to finally relate this cell division to humans. Although this lesson has been primarily designed for GCSE students (14 - 16 year olds in the UK), it is highly suitable for A-level lessons, especially if a teacher wants to recap on this cell division before extending knowledge.

A detailed lesson which looks at the type of cell division known as mitosis and aims to ensure that students understand that it leads to the production of genetically identical daughter cells. In order to understand this type of cell division and any related topic such as meiosis, students have to be confident with the use of terms like diploid. In addition to this, time is taken to introduce them to a way of considering the quantity of DNA within a cell in terms of n. If they are able to use this correctly, then no matter the organism which is involved in a mitosis exam question, they will be able to answer successfully. Discussion points and progress checks are written into the lesson at regular intervals so their understanding can be assessed. The last part of the lesson provides the students with an opportunity to apply their knowledge of mitosis to a range of exam questions and they can assess against the displayed mark schemes. This lesson has been designed for GCSE students (14 - 16 year olds in the UK) but is also appropriate for older students who want to recap on the key details of the division before extended knowledge is added.

A fully-resourced lesson which has been designed for GCSE students and includes an engaging lesson presentation and associated worksheets. This lesson looks at the three limiting factors of photosynthesis, focusing on the graphs that they produce and ensures that students can explain why temperature is a factor. This lesson begins by introducing the students to the definition of a limiting factor. They are challenged to recognise that it would be photosynthesis which is limited by carbon dioxide concentration and light intensity. The third factor, temperature, is not introduced until later in the lesson so that students are given thinking time to consider what it might be. Having been presented with two sets of data, students are asked to draw sketch graphs to represent the trend. The limiting factors on the light intensity graph are taught to the students so they can use this when working out the limiting factors on the carbon dioxide graph. The remainder of the lesson focuses on temperature and more specifically why a change in this factor would cause a change in the rate of photosynthesis because of enzymes. The student’s knowledge of that topic is tested alongside. Progress checks have been written into the lesson at regular intervals so that students can constantly assess their understanding.

A highly engaging lesson that looks at the structures that are found in the 1st line of defence and explores the methods of action use by phagocytes and lymphocytes. This lesson has been designed for GCSE students but could be used as an initial recap with A-level students before they go on to learn this topic in greater detail The lesson begins by introducing the meaning of the 1st line of defence. A quick competition is used to challenge the students to recognise the names of some of these structures when their names have some letters missing. Time is taken to discuss the action of the cilia and skin and then students are challenged to make links to the related topics of enzymes and pH as they complete a passage about the role of hydrochloric acid in the stomach. Moving forwards, students will learn that there are two types of white blood cells, phagocytes and lymphocytes, and the details of their actions is explored. Key points such as the specificity of antibodies and the involvement of enzymes are discussed in detail so that this topic can be understood to the depth needed at this level. In addition to a number of games to maintain engagement, progress checks are written into this at regular intervals to allow the students to assess their understanding.

This lesson looks at the two stages of protein synthesis, transcription and translation, and focuses on the key details that students need to understand this potentially difficult topic. The lesson presentation has been deliberately written in a concise way to encourage the students to summarise the two stages and pick out the key points which will enable them to form longer answers when necessary. The lesson begins by introducing the students to RNA, and a quick check is done to see how much they can recall about the other nucleic acid, DNA. Moving forwards, students are challenged to study the structure of DNA and RNA in SPOT THE DIFFERENCE before being challenged to explain why RNA is necessary in this process. Time is taken to look at important sections such as complimentary base pairing and the identification of amino acids from the codon. A number of quick competitions have been written into the lesson to maintain engagement and the progress checks are regular so that students assess their understanding and any misconceptions can be quickly identified and addressed. This lesson has been written for GCSE students but should a teacher want to teach an introduction lesson on protein synthesis before going into more detail at a later date, then this would be suitable.

This fully-resourced lesson explores the inheritance of genetic characteristics that involve multiple alleles and codominant alleles. The engaging and detailed PowerPoint and differentiated worksheets have been designed to cover the part of point 6.1.2 (b[i]) which states that students should be able to demonstrate and apply their knowledge and understanding of genetic diagrams to show patterns of inheritance including multiple and codominant alleles. The main part of the lesson uses the inheritance of the ABO blood groups to demonstrate how the three alleles that are found at the locus on chromosome 9 and the codominance of the A and B alleles affects the phenotypes. Students are guided through the construction of the different genotypes and how to interpret the resulting phenotype. They are challenged to use a partially completed pedigree tree to determine the blood group for some of the family members and to explain how they came to their answer. To further challenge their ability to apply their knowledge, a series of questions about multiple alleles and codominance in animals that are not humans are used. The final part of the lesson makes a link back to module 4 and the correlation between a high proportion of polymorphic gene loci and an increase in genetic diversity. Students will be expected to make links between module 4 and 6 as part of papers 2 and 3, so this demonstrates how exam questions can do just that

This is an engaging and informative lesson that looks at the properties of water and challenges students to be able to explain how these properties are related to the numerous functions of this biological molecule. This lesson focuses on the link between properties and functions which is the area where students commonly struggle. A range of tasks and activities, including a quick competition are used to introduce the different properties and the key terms and then time is taken to look at how this property enables water to be used for a range of functions. Students will learn that water has both a high specific heat capacity and a high latent heat of vaporisation and be able to explain why this is important. Water is a crucial solvent which enables it to perform many roles in living organisms and these are explored. Progress checks are written into the lesson at regular intervals so that students can constantly assess their understanding and build on any knowledge that was there from GCSE.

This fully-resourced lesson explores the contributions of chromosome mutations to genetic variation. The engaging PowerPoint and accompanying worksheets have been designed and written to cover the part of point 6.1.2 (a) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the contribution of genetic factors to phenotypic variation Over the course of the lesson, students will encounter a number of chromosome mutations and see the conditions which they cause. Time is taken to look at non-disjunction and how this can result in Down, Turner’s and Klinefelter’s syndromes. Students are guided through a description of the formation of gametes and zygotes with abnormal numbers of chromosomes before being challenged to describe the formation of a zygote with Turner’s syndrome. Moving forwards, translocation and polyploidy are also discussed. Progress checks are written into the lesson at regular intervals, that not only check the learning from this lesson but also from related topics (such as meiosis) and this enables the students to constantly assess their understanding.

This engaging lesson looks at the role of haemoglobin in transporting oxygen and carbon dioxide and compares the dissociation curves for foetal and adult haemoglobin. The detailed PowerPoint has been designed to cover points 3.1.2 (i & j) of the OCR A-level Biology A specification and includes references to the role of carbonic anhydrase and the formation of haemoglobinic acid and carbaminohaemoglobin. The lesson begins with a version of the quiz show Pointless to introduce haemotology as the study of the blood conditions. Students are told that haemoglobin has a quaternary structure and are challenged to use their prior knowledge of biological molecules to determine what this means for the protein. They will learn that each of the 4 polypeptide chains contains a haem group with an iron ion attached and that it is this group which has a high affinity for oxygen. Time is taken to discuss how this protein must be able to load (and unload) oxygen as well as transport the molecules to the respiring tissues. Students will plot the oxyhaemoglobin dissociation curve and the S-shaped curve is used to encourage discussions about the ease with which haemoglobin loads each molecule. At this point, foetal haemoglobin and its differing affinity of oxygen is introduced and students are challenged to predict whether this affinity will be higher or lower than adult haemoglobin and to represent this on their dissociation curve. The remainder of the lesson looks at the different ways that carbon dioxide is transported around the body that involve haemoglobin. Time is taken to look at the dissociation of carbonic acid into hydrogen ions so that students can understand how this will affect the affinity of haemoglobin for oxygen in an upcoming lesson on the Bohr effect. It is estimated that it will take in excess of 2 hours of A-level teaching time to cover the detail of these two specification points as covered in this lesson

This fully-resources lesson looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration affects the dissociation of oxyhaemoglobin. The PowerPoint has been designed to cover the second part of point 3.1.2 (j) of the OCR A-level Biology A specification and continually ties in with the previous lesson on the role of haemoglobin. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual. These questions are differentiated to allow students of differing abilities to access the work and to be challenged