This clear and concise lesson explains how the inheritance of two or more genes that have loci on the same chromosome demonstrates autosomal linkage. The engaging PowerPoint and associated resource have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems that involve autosomal linkage.
This is a topic which can cause confusion for students so time was taken in the design to split the concept into small chunks. There is a clear focus on how the number of original phenotypes and recombinants can be used to determine linkage and suggest how the loci of the two genes compare. Important links to other topics such as crossing over in meiosis are made to enable students to understand how the random formation of the chiasma determines whether new phenotypes will be seen in the offspring or not. Linkage is an important cause of variation and the difference between observed and expected results and this is emphasised on a number of occasions. The main task of the lesson acts as an understanding check where students are challenged to analyse a set of results involving the inheritance of the ABO blood group gene and the nail-patella syndrome gene to determine whether they have loci on the same chromosome and if so, how close their loci would appear to be.
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Topic 16: Inherited change (CIE A-level Biology)
Meiosis, genetic inheritance and the control of gene expression are some of the harder topics on this A-level Biology course and all three are covered in topic 16 (Inherited change) of the CIE A-level Biology specification. The 10 lessons included in this bundle have been planned at length and contain a wide range of tasks that cover the detailed content whilst checking on understanding and key terms and values are introduced through engaging quiz competitions. The following topic 16 specification points are covered by these lessons: Topic 16.1 * The meaning of a homologous pair of chromosomes * The behaviour of chromosomes in animal and plant cells during meiosis * Genetic variation is caused by crossing over, random assortment and the random fusion of gametes at fertilisation Topic 16.2 * The meaning of key genetic terms * Using genetic diagrams to solve problems involving mohohybrid and dihybrid crosses, including those involving autosomal linkage, sex linkage, codominance, multiple alleles and gene interactions * Use the chi-squared test to test the significance of differences between observed and expected results * Gene mutations occur by substitution, deletion and insertion and may affect the phenotype Topic 16.3 * The genetic control of protein production in a prokaryote as shown by the lac operon * The function of transcription factors in gene expression in eukaryotes * Gibberellins and DELLA protein repressors If you would like to sample the quality of the lessons included in this bundle, then download the autosomal linkage and chi-squared test lessons as these have been uploaded for free
Topic 16.2 [b]: The roles of genes in determining the phenotype (CIE A-level Biology)
Each of the 5 lessons within this bundle are fully-resourced and cover the content of point (b) of topic 16.2 of the CIE A-level Biology specification which states that students should be able to use genetic diagrams to solve problems which involve the following: * monohybrid and dihybrid crosses * autosomal linkage * sex-linkage * codominance * multiple alleles * gene interactions Students are guided through the construction of the genetic diagrams for the inheritance of one or two genes and are shown how to analyse the phenotypic ratios to determine whether linkage has occurred or whether a gene interaction is involved. The wide range of activities which includes exam questions with visual mark schemes, differentiated tasks and quiz competitions will maintain engagement whilst providing the students with opportunities to assess their progress against the current topic
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Thanks again for your professional work on these PPTs
Another excellent resource to keep students engaged with online lessons. Many thanks.
Great resource for my students, everything broke down and explained really well with fun activities.
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