This detailed lesson describes how the anti-sense strand of DNA is used as template to form messenger RNA (mRNA) during transcription. The PowerPoint and accompanying resource have been designed to cover the first part of point 1.4 (vi) as detailed in the Edexcel A-level Biology B specification.
The lesson begins by challenging the students to recall that most of the nuclear DNA in eukaryotes does not code for polypeptides. This allows the promoter region and terminator region to be introduced, along with the structural gene. Through the use of an engaging quiz competition, students will learn that the strand of DNA involved in transcription is known as the anti-sense strand and the other strand is the sense strand. Links to previous lessons on DNA and RNA structure are made throughout and students are continuously challenged on their prior knowledge as well as they current understanding of the lesson topic. Moving forwards, the actual process of transcription is covered in a 7 step bullet point description where the students are asked to complete each passage using the information previously provided as well as their own biological knowledge. An exam-style question is used to check on their understanding before the final task of the lesson looks at the journey of mRNA to the ribosome for the next stage of translation.
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Topic 1: Biological molecules (Edexcel A-level Biology B)
The biological molecules topic is incredibly important, not just because it is found at the start of the course, but also because of its detailed content which must be well understood to promote success with the other 9 Edexcel A-level Biology B topics. Many hours of intricate planning has gone into the design of all of the 19 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: * The differences between monosaccharides, disaccharides and polysaccharides * The structure of glucose and ribose * The formation of disaccharides and polysaccharides from monosaccharides * The structure of starch, glycogen and cellulose * The synthesis of a triglyceride * The differences between saturated and unsaturated lipids * The relationship between the structure of lipids and their roles * The structure and properties of phospholipids * The structure of an amino acid * The formation of polypeptides and proteins * The role of ionic, hydrogen and disulphide bonding in proteins * The levels of protein structure * The structure of collagen and haemoglobin * The structure of DNA * The semi-conservative replication of DNA * A gene is a sequence of bases on DNA that codes for an amino acid sequence * The structure of mRNA * The structure of tRNA * The process of transcription * The process of translation * Base deletions, insertions and substitutions as gene mutations * The effect of point mutations on amino acid sequences * The structure of enzymes as globular proteins * The concept of specificity and the induced-fit hypothesis * Enzymes are catalysts that reduce activation energy * Understand how temperature affects enzyme activity * Enzymes catalyse a wide range of intracellular reactions as well as extracellular ones * The role of inorganic ions in plants * The importance of water for living organisms Due to the detail included in these lessons, it is estimated that it will take in excess of 2 months of allocated A-level teaching time to complete. If you would like to see the quality of the lessons then download the monosaccharides, disaccharides and polysaccharides, glucose and ribose, triglycerides, structure of DNA and transcription lessons as these have been uploaded for free.
Topic 1.4: DNA and protein synthesis (Edexcel A-level Biology B)
This bundle of 6 fully-resourced lessons have been designed to cover the content as detailed in topic 1.4 of the Edexcel A-level Biology B specification. The specification points in this DNA and protein synthesis topic which are covered by the lessons are as follows: * The structure of DNA * The semi-conservative replication of DNA * A gene is a sequence of bases on DNA that codes for an amino acid sequence * The structure of mRNA * The structure of tRNA * The process of transcription * The process of translation * Base deletions, insertions and substitutions as gene mutations * The effect of point mutations on amino acid sequences The engaging PowerPoint lessons and accompanying resources contain a wide range of activities and tasks that include exam-style questions with displayed mark schemes, quick quiz competitions, useful hints and discussion periods. If you would like to see the quality of the lessons then download the structure of DNA and transcription lessons as these have been uploaded for free.
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