A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
Without doubt, the CIE A-level Biology specification contains a lot of maths calculations and every year, there are a large number of exam questions that require the application of a range of mathematical skills. Therefore, a clear understanding of how and when to apply these skills is closely related to success on this course and the following calculations are covered by the 7 lessons that are included in this bundle:
Using the eyepiece graticule and stage micrometer to measure cells and be familiar with units
Calculating actual sizes of specimens from drawings, photomicrographs and electron micrographs
Using the chi-squared test to determine significance between the observed and expected results of a genetic cross
Use the t-test to compare the variation of two populations
Using the Hardy Weinberg principle to calculate allele, genotype and phenotype frequencies in populations
Use Spearman’s rank correlation to analyse relationships between the distribution and abundance of species and abiotic or biotic factors
Using Simpson’s index of diversity to calculate the biodiversity of a habitat
All of the lessons contain step by step guides that walk the students through the application of the formulae and there are lots of worked examples and exam-style questions for the students to use to assess understanding
“Overall, at least 10% of the marks in assessments for biology will require the use of mathematical skills”
This sentence is taken directly from the AQA A-level Biology specification and clearly shows that being able to apply these skills in the context of biology will have a significant impact on a student’s chances of success.
This bundle has been created to cover as much of those mathematical skills as possible and the following specification points are covered by these 6 lessons:
Represent phenotypic ratios (monohybird and dihybrid crosses)
Use and manipulate the magnification formula
Use the chi-squared test to test the significance of the difference between observed and expected results
Use the Hardy-Weinberg principle to calculate changes in allele frequency
Calculate an index of diversity for a habitat
A revision lesson is also included in this bundle which acts as a fun and engaging revision of the range of calculations
This lesson describes how large molecules are hydrolysed to smaller molecules by the enzymes produced by the digestive system in mammals. The detailed PowerPoint and accompanying worksheets are part of the 1st lesson in a series of 2 which have been designed to cover the content of point 3.3 of the AQA A-level Biology specification and this lesson includes descriptions of the action of amylase, disaccharidases, lipase, endopeptidases, exopeptidases and dipeptidases.
The lesson has been designed to walk the students through the functions of the digestive system at each point of the digestive tract up until the duodenum and focuses on the action of the enzymes produced in the mouth, stomach and small intestine and by the accessory organs of the system. Time is taken to describe and explain key details, such as the fact that endopeptidases cleave peptide bonds within the molecules, meaning that they cannot break down proteins into monomers. The lesson is filled with exam-style questions which will develop their understanding of the current topic as well as checking on their knowledge of related topics which have been previously-covered such as the structure of the biological molecules and qualitative tests. In addition to the detailed content and regular questioning, the lesson PowerPoint contains guided discussion periods and two quick quiz competitions which introduce a key term and a key value in a fun and memorable way
This lesson has been specifically planned to prepare the students for the very next lesson where the mechanisms for the absorption of the products of digestion are described.
Photosynthesis and respiration are two of the most commonly assessed topics in A-level exams but these questions are sometimes poorly answered by students due to a lack of understanding or an inability to apply their knowledge. With this in mind, these 8 lessons have been intricately planned to contain a wide range of activities that will engage and motivate the students whilst covering the key detail to try to deepen their understanding and includes exam-style questions so they are fully prepared for these assessments.
The following specification points in topics 5 and 7 of the Edexcel International A-level Biology specification are covered by these lessons:
Understand the overall reaction of photosynthesis
Understand the light-dependent reactions of photosynthesis including the role of these electrons in generating ATP, reducing NADP in photophosphorylation and producing oxygen through photolysis of water
Understand the light-independent reactions as reduction of carbon dioxide using the products of the light-dependent reactions
Know that the products are simple sugars that are used by plants, animals and other organisms in respiration and the synthesis of new biological molecules
Understand the structure of chloroplasts in relation to their role in photosynthesis
Understand the overall reaction of aerobic respiration
Understand that respiration is a many-stepped process with each step controlled and catalysed by a specific intracellular enzyme
Understand the roles of glycolysis in aerobic and anaerobic respiration
Understand the role of the link reaction and the Krebs cycle in the complete oxidation of glucose and formation of carbon dioxide, ATP, reduced NAD and reduced FAD
Understand how ATP is synthesised by oxidative phosphorylation
If you would like to sample the quality of the lessons in this bundle then download the products of photosynthesis lesson as this has been shared for free
This lesson describes the principle components of the plasma membrane, focusing on the phospholipid bilayer and membrane proteins. The detailed PowerPoint and accompanying worksheets have been designed to cover the detail in point (a) of AS unit 1, topic 3 of the WJEC A-level Biology specification and clear links are made to Singer and Nicholson’s fluid mosaic model
The fluid mosaic model is introduced at the start so that it can be referenced at appropriate points throughout the lesson. Students were introduced to phospholipids in topic 1 and so an initial task challenges them to spot the errors in a passage describing the structure and properties of this molecule. This reminds them of the bilayer arrangement, with the hydrophilic phosphate heads protruding outwards into the aqueous solutions on the inside and the outside of the cell. In a link to some upcoming lessons on the transport mechanisms, the students will learn that only small, non-polar molecules can move by simple diffusion and that this is through the tails of the bilayer. This introduces the need for transmembrane proteins to allow large or polar molecules to move into the cell by facilitated diffusion and active transport. Proteins that act as receptors as also introduced and an opportunity is taken to make a link to an upcoming topic so that students can understand how hormones or drugs will bind to target cells in this way. Moving forwards, the structure of cholesterol is covered and students will learn that this hydrophobic molecule sits in the middle of the tails and therefore acts to regulate membrane fluidity. The final part of the lesson challenges the students to apply their newly-acquired knowledge to a series of questions where they have to explain why proteins may have moved when two cells are used and to suggest why there is a larger proportion of these proteins in the inner mitochondrial membrane than the outer membrane.
Photosynthesis and respiration are two of the most commonly assessed topics in A-level exams but are often poorly understood by students. These 9 lessons have been intricately planned to contain a wide range of activities that will engage and motivate the students whilst covering the key detail to try to deepen their understanding and includes exam-style questions so they are fully prepared for these assessments.
The following specification points in topics 5 and 7 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification are covered by these lessons:
Understand the overall reaction of photosynthesis
Understand the light-dependent reactions of photosynthesis including the role of these electrons in generating ATP, reducing NADP in photophosphorylation and producing oxygen through photolysis of water
Understand the light-independent reactions as reduction of carbon dioxide using the products of the light-dependent reactions
Know that the products are simple sugars that are used by plants, animals and other organisms in respiration and the synthesis of new biological molecules
Understand the structure of chloroplasts in relation to their role in photosynthesis
Understand the overall reaction of aerobic respiration
Understand that respiration is a many-stepped process with each step controlled and catalysed by a specific intracellular enzyme
Understand the roles of glycolysis in aerobic and anaerobic respiration
Understand the role of the link reaction and the Krebs cycle in the complete oxidation of glucose and formation of carbon dioxide, ATP, reduced NAD and reduced FAD
Understand how ATP is synthesised by oxidative phosphorylation
Understand what happens to lactate after a period of anaerobic respiration in animals
If you would like to sample the quality of the lessons in this bundle then download the light independent reactions, the link reaction and Krebs cycle and the fate of lactate lessons as these have been shared for free
This lesson describes the transport mechanism of osmosis as the movement of water molecules from a high water potential to a lower water potential. The PowerPoint and accompanying resources are part of the second lesson in a series of 4 lessons which have been designed to cover point [c] as detailed in AS unit 1, topic 3 of the WJEC A-level Biology specification and also describes how cells are affected by this movement of water
It’s likely that students will have used the term concentration in their osmosis definitions at GCSE, so the aim of the starter task is to introduce water potential to allow students to begin to recognise osmosis as the movement of water molecules from a high water potential to a lower potential, with the water potential gradient. Time is taken to describe the finer details of water potential to enable students to understand that 0 is the highest value (pure water) and that this becomes negative once solutes are dissolved. Exam-style questions are used throughout the lesson to check on current understanding as well as prior knowledge checks which make links to previously covered topics such as the lipid bilayer of the cell membrane. The remainder of the lesson focuses on the movement of water when animal and plant cells are suspended in hypotonic, hypertonic or isotonic solutions and the final appearance of these cells is described, including any issues this may cause.
This lesson describes the relationship between the specialised features of the mammalian egg and sperm and their functions. The PowerPoint and accompanying resources have been designed to cover point 3.11 of the Edexcel International A-level Biology specification and includes a focus on the acrosome in the head of the sperm and the zona pellucida in the egg
The lessons at the start of topic 3 (Cell structure, Reproduction and Development) described the ultrastructure of eukaryotic cells, so this knowledge is referenced throughout the lesson and the students are challenged on their recall and understanding through a range of prior knowledge checks. For example, two of the exam-style questions that are included in the resources challenge the students to explain why a sperm cell is classified as an eukaryotic cell and to recognise the centrioles and the nucleus from structural descriptions. Along with the mitochondria, time is then taken to discuss and to describe the role of these organelles in relation to the function of the sperm cell. When considering the fusion of the haploid nuclei to form a diploid nucleus in the nucleus, links are made to the upcoming topic of mitosis and the significance of this form of nuclear division. The importance of the enzymes that are found inside the acrosome is emphasised and this leads into the second half of the lesson where the layers surrounding the plasma membrane of the egg cell (corona radiata and zona pellucida) are examined
The final part of this lesson has been specifically planned to prepare the students for the next lesson in topic 3, where the acrosome reaction, cortical reaction and the fusion of nuclei that are involved in fertilisation are described
This lesson explains the need for specialised exchange surfaces and uses examples to describe the features of an efficient exchange surface. The PowerPoint and accompanying worksheets have been designed to cover points 3.1.1 (a & b) of the OCR A-level Biology A specification and also have been specifically planned to prepare the students for the upcoming lessons in module 3 on gas exchange and mass transport in animals.
The students are likely to have been introduced to the surface area to volume ratio at GCSE, but understanding of its relevance tends to be mixed. Therefore, real life examples are included throughout the lesson that emphasise the importance of this ratio in order to increase this relevance. A lot of students worry about the maths calculations that are associated with this topic so a step by step guide is included at the start of the lesson that walks them through the calculation of the surface area, the volume and then the ratio. Through worked examples and understanding checks, SA/V ratios are calculated for cubes of increasing side length and living organisms of different size. These comparative values will enable the students to conclude that the larger the organism or structure, the lower the surface area to volume ratio. A differentiated task is then used to challenge the students to explain the relationship between the ratio and the metabolic demands of a single-celled and multicellular organisms and this leads into the next part of the lesson, where the adaptations of large organisms to increase this ratio at the exchange surfaces are covered. The students will calculate the SA/V ratio of a human alveolus (using the surface area and volume formulae for a sphere) and will see the significant increase that results from the folding of the membranes. In addition to the ratio, time is taken to discuss and describe how the maintenance of a steep concentration gradient and a thin membrane are important for the rate of diffusion and again biological examples are used in humans and other organisms to increase the understanding. Fick’s law of diffusion is also introduced as a mechanism to help the students to recall that surface area, concentration difference and thickness of membrane govern the rate of simple diffusion.
As well as making links to upcoming topics, prior knowledge checks are used to challenge the students on their knowledge of previously-covered modules which include inorganic ions, organelles, cell membrane transport and tissues.
This lesson describes how Fick’s law of diffusion is governed by the three main properties of gas exchange surfaces in living organisms. The PowerPoint and accompanying worksheets have been designed to cover points 2.1 (i & ii) of the Edexcel International A-level Biology specification and there is a particular focus on the relationship between the size of an organism or structure and its surface to volume ratio.
Adolf Fick is briefly introduced at the start of the lesson and the students will learn that his law of diffusion governs the diffusion of a gas across a membrane and is dependent on three properties. The students are likely to know that surface area is one of these properties but although they may have been introduced to the surface area to volume ratio at iGCSE, their understanding of its relevance tends to be mixed. Therefore, real life examples are included throughout the lesson that emphasise the importance of this ratio in order to increase the relevance. A lot of students worry about the maths calculations that are associated with this topic so a step by step guide is included at the start of the lesson to walk them through the calculation of the surface area, the volume and then the ratio. Through worked examples and understanding checks, SA/V ratios are calculated for cubes of increasing side length and living organisms of different size. These comparative values will enable the students to conclude that the larger the organism or structure, the lower the surface area to volume ratio. A differentiated task is then used to challenge the students to explain the relationship between the ratio and the metabolic demands of an organism and this leads into the next part of the lesson, where the adaptations of a human to increase the ratio at the gas exchange surface is covered. The students will calculate the SA/V ratio of a human alveolus (using the surface area and volume formulae for a sphere) and will see the significant increase that results from the folding of the membranes. The remainder of the lesson introduces concentration difference and thickness of membrane as the other two properties in Fick’s law of diffusion and students are reminded that the maintenance of a steep concentration gradient and a reduction in the diffusion distance are critical for this transport mechanism.
This lesson has been specifically planned to prepare students for the next lesson which describes how the structure of the mammalian lung is adapted for rapid gas exchange (specification point 2.1 [iii])
This lesson describes the relationship between the size of an organism or structure and its surface to volume ratio. The PowerPoint and accompanying worksheets have been designed to cover point 3.1 of the AQA A-level Biology specification and also have been specifically planned to prepare the students for the upcoming lessons in topic 3 on gas exchange and absorption in the ileum.
The students are likely to have been introduced to the ratio at GCSE, but understanding of its relevance tends to be mixed. Therefore, real life examples are included throughout the lesson that emphasise the importance of the surface area to volume ratio in order to increase this relevance. A lot of students worry about the maths calculations that are associated with this topic so a step by step guide is included at the start of the lesson that walks them through the calculation of the surface area, the volume and then the ratio. Through worked examples and understanding checks, SA/V ratios are calculated for cubes of increasing side length and living organisms of different size. These comparative values will enable the students to conclude that the larger the organism or structure, the lower the surface area to volume ratio. A differentiated task is then used to challenge the students to explain the relationship between the ratio and the metabolic demands of an organism and this leads into the next part of the lesson, where the adaptations of larger organisms to increase the ratio at their exchange surfaces is covered. The students will calculate the SA/V ratio of a human alveolus (using the surface area and volume formulae for a sphere) and will see the significant increase that results from the folding of the membranes. This is further demonstrated by the villi and the microvilli on the enterocytes that form the epithelial lining of these folds in the ileum. The final part of the lesson introduces Fick’s law of diffusion so that students are reminded that the steepness of a concentration gradient and the thickness of a membrane also affect the rate of diffusion.
This lesson describes the gross structure of the human gas exchange system, including the trachea, bronchi, bronchioles and lungs. The PowerPoint and accompanying resources are part of the third lesson in a series of 6 which have been designed to cover the detail of topic 3.2 in the AQA A-level Biology specification which is titled gas exchange and this lesson has been specifically planned to prepare students for the next lesson where the essential features of the alveoli are described.
The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features:
The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea
The narrowing airways of the primary, secondary and tertiary bronchi
The elastic fibres and smooth muscle in the terminal and respiratory bronchioles
The pleural cavity and fluid of the lungs
When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for the topic of inheritance (7.1)
This lesson describes the gross structure of the human gas exchange system and the functions of the structural components like goblet cells. The PowerPoint and accompanying resources have been designed to cover points 9.1 (a & c) of the CIE A-level Biology specification and has been specifically planned to prepare students for an upcoming lesson where the gas exchange between the alveoli and the blood is described.
The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features:
The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea
The narrowing airways of the primary, secondary and tertiary bronchi
The elastic fibres and smooth muscle in the terminal and respiratory bronchioles
The pleural cavity and fluid of the lungs
When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for topic 16 (Inherited change)
This bundle contains 7 lessons which are highly detailed and cover the following points in the surface area to volume ratio, gas exchange and digestion and absorption topics of the AQA A-level Biology specification:
The relationship between the size of an organism or structure and its surface area to volume ratio
The development of systems in larger organisms as adaptations that facilitate exchange as this ratio reduces
Adaptations of gas exchange surfaces in single-celled organisms, insects, bony fish and in the leaf of a dicotyledonous plant
The gross structure of the human gas exchange system
The essential features of the alveolar epithelium over which gas exchange takes place
Ventilation and the exchange of gases in the lungs
Digestion in mammals of carbohydrates, proteins and lipids
Mechanisms for the absorption of the products of digestion by cells lining the ileum
If you would like to sample the quality of lessons in this bundle, then download the alveolar epithelium and absorption in the ileum lessons as these have been uploaded for free
This lesson describes the characteristic features of the Animalia, Plantae, Fungi, Protoctista and Prokaryotae kingdoms. The engaging PowerPoint and accompanying resources have been designed to cover point (d) in AS unit 2, topic 1 of the WJEC A-level Biology specification
This lesson begins with a knowledge recall as students have to recognise that prior to 1990, kingdom was the highest taxa in the classification hierarchy. Moving forwards, they will recall the names of the five kingdoms and immediately be challenged to split them so that the prokaryotae kingdom is left on its own. An opportunity is taken at this point to check on their prior knowledge of the structure of a bacterial cell as covered in unit 1, topic 2. These prior knowledge checks are found throughout the lesson (along with current understanding checks) as students are also tested on their knowledge of the structure and function of cellulose. This is found in the section of the lesson where the main constituent of the wall can be used to distinguish between plantae, fungi and prokaryotae. Quick quiz competitions, such as YOU DO THE MATH and SAY WHAT YOU SEE are used to introduce key values and words in a fun and memorable way. The final part of the lesson looks at the protoctista kingdom and students will come to understand how these organisms tend to share a lot of animal or plant-like features.
Both of the accompanying resources have been differentiated to allow students of differing abilities to access the work and this lesson has been written to tie in with the previously uploaded lesson on classification and the binomial naming system
This lesson describes how biodiversity is generated through natural selection and leads to behavioural, anatomical and physiological adaptations. The PowerPoint and accompanying resources have been designed to cover specification points (m) & (n) in AS unit 2, topic 1 of the WJEC A-level Biology specification
President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. Moving forwards, 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of evolution through natural selection. The main task of the lesson challenges the students to form a description that explains how this strain of bacteria developed resistance to methicillin to enable them to see the principles of natural selection. This can then be used when describing how the anatomy of the modern-day giraffe has evolved over time. The concept of convergent evolution is introduced and links are made to the need for modern classification techniques as covered earlier in topic 1. Moving forwards, students will understand how natural selection leads to adaptations and a quick quiz competition introduces the different types of adaptation and a series of tasks are used to ensure that the students can distinguish between anatomical, behavioural and physiological adaptations. The Marram grass is used to test their understanding further, before a step by step guide describes how the lignified cells prevent a loss of turgidity. Moving forwards, the students are challenged to explain how the other adaptations of this grass help it to survive in its environment. A series of exam-style questions on the Mangrove family will challenge them to make links to other topics such as osmosis and the mark schemes are displayed to allow them to assess their understanding. The final part of the lesson focuses on the adaptations of the anteater but this time links back to the topic of taxonomy and students have to answer questions about species and classification hierarchy.
Due to the extensiveness of this lesson and the detail contained within the resources, it is estimated that it will take in excess of 2 hours of allocated A-level teaching time to deliver this lesson.
This lesson explains the meaning of biodiversity and describes how it can be assessed in a habitat, in a species level at a genetic level and at a molecular level. The engaging PowerPoint and accompanying resources have been designed to cover points (h-l) in AS unit 2, topic 1 of the WJEC A-level Biology specification but as a lot of genetic content is covered when considering diversity within a species, this lesson can be used as an introduction to the upcoming topics of inheritance
A quiz competition called BIOLOGICAL TERMINOLOGY SNAP runs over the course of the lesson and this will engage the students whilst challenging them to recognise key terms from their definitions. This quiz introduces biodiversity, loci, allele and recessive and each of these terms is put into context once introduced. Once biodiversity has been revealed, the students will learn that they are expected to be able to assess the biodiversity within a habitat and within a species and at a molecular level.
The variety of alleles in the gene pool of a population increases the genetic diversity so a number of examples are used to demonstrate how the number of phenotypes increases with the number of alleles at a locus. The CFTR gene is used to demonstrate how 2 alleles results in 2 different phenotypes and therefore genetic diversity. Moving forwards, students will discover that more than 2 alleles can be found at a locus and they are challenged to work out genotypes and phenotypes for a loci with 3 alleles (shell colour in snails) and 4 alleles (coat colour in rabbits).
Moving forwards, a step by step guide to complete a worked example to calculate a value of D using Simpson’s index of diversity. Students are challenged with a range of exam-style questions where they have to apply their knowledge and all mark schemes are displayed and clearly explained within the PowerPoint to allow students to assess their understanding and address any misconceptions if they arise.
The final part of the lesson considers how DNA fingerprinting can be used to assess biodiversity at a molecular level and again a series of exam-style questions are used to challenge the students to apply their newly-acquired knowledge to an unfamiliar situation.
This lesson bundle contains 9 lessons which have been designed to cover the Edexcel International A-level Biology specification points which focus on the structure and function of the biological molecules, including water, carbohydrates, lipids and proteins. The lesson PowerPoints are highly detailed, and along with their accompanying worksheets, they have been planned at length to contain a wide range of engaging tasks which cover the following A-level Biology content that’s found in topics 1, 2 and 4 of the course:
1.1: Understand the importance of water as a solvent in transport, including its dipole nature
1.2 (i): Know the difference between monosaccharides, disaccharides and polysaccharides, including glycogen and starch (amylose and amylopectin)
1.2 (ii): Be able to relate the structures of monosaccharides, disaccharides and polysaccharides to their roles in providing and storing energy
1.4: Know how monosaccharides join to form disaccharides (sucrose, lactose and maltose) and polysaccharides (glycogen and amylose) through condensation reactions forming glycosidic bonds, and how these can be split through hydrolysis reactions
1.5 (i): Know how a triglyceride is synthesised by the formation of ester bonds
during condensation reactions between glycerol and three fatty acids.
1.5 (ii): Know the differences between saturated and unsaturated lipids
2.6 (i): Know the basic structure of an amino acid
2.6 (ii): Understand the formation of polypeptides and proteins (amino acid
monomers linked by peptide bonds in condensation reactions)
2.6 (iii): Understand the significance of a protein’s primary structure in determining its three-dimensional structure and properties (globular and fibrous proteins and the types of bonds involved in its three-dimensional structure)
4.3: Understand the structure and function of the polysaccharides starch and
cellulose, including the role of hydrogen bonds between β-glucose molecules in
the formation of cellulose microfibrils
This lesson bundle contains 16 lessons which have been designed to cover the Edexcel International A-level Biology specification points which focus on the structure of DNA and RNA, their roles in replication and protein synthesis, and genetics and inheritance. The lesson PowerPoints are highly detailed, and along with their accompanying worksheets, they have been planned at length to contain a wide range of engaging tasks which cover the following A-level Biology content found in topics 2, 3 and 6 of the course:
2.9 (i): Know the basic structure of mononucleotides (deoxyribose or ribose linked to a phosphate and a base, including thymine, uracil, adenine, cytosine or guanine) and the structures of DNA and RNA (polynucleotides composed of mononucleotides linked by condensation reactions to form phosphodiester bonds)
2.9 (ii): Know how complementary base pairing and the hydrogen bonding between two complementary strands are involved in the formation of the DNA double helix
2.10 (i): Understand the process of DNA replication, including the role of DNA polymerase
2.11: Understand the nature of the genetic code
2.12: Know that a gene is a sequence of bases on a DNA molecule that codes for a sequence of amino acids in a polypeptide chain
2.13 (i): understand the process of protein synthesis (transcription and translation), including the role of RNA polymerase, translation, messenger RNA, transfer RNA, ribosomes and the role of start and stop codons
2.13 (ii): Understand the roles of the DNA template (antisense) strand in transcription, codons on messenger RNA and anticodons on transfer RNA
2.14 (i): Understand how errors in DNA replication can give rise to mutations (substitution, insertion and deletion of bases)
2.14 (ii): Know that some mutations will give rise to cancer or genetic disorders, but that many mutations will have no observable effect
2.15 (i): Know the meaning of the terms: gene, allele, genotype, phenotype, recessive, dominant, codominance, homozygote and heterozygote
2.15 (ii): Understand patterns of inheritance, including the interpretation of genetic pedigree diagrams, in the context of monohybrid inheritance
2.15 (iii): Understand sex linkage on the X chromosome, including red-green colour blindness in humans
2.16: Understand how the expression of a gene mutation in people with cystic fibrosis impairs the functioning of the gaseous exchange, digestive and reproductive systems
2.17 (i): Understand the uses of genetic screening, including the identification of carriers, pre-implantation genetic diagnosis (PGD) and prenatal testing, including amniocentesis and chorionic villus sampling
2.17 (ii): Understand the implications of prenatal genetic screening
3.9 (i): Know that a locus is the location of genes on a chromosome
3.9 (ii): Understand the linkage of genes on a chromosome
3.18: Understand how cells become specialised through differential gene expression, producing active mRNA, leading to the synthesis of proteins which, in turn, control cell processes or determine cell structure in animals and plants
3.19: Understand how one gene can give rise to more than one protein through posttranscriptional changes to messenger RNA (mRNA).
3.20 (i): Phenotype is an interaction between genotype and the environment
3.21: Understand how some phenotypes are affected by multiple alleles for the same gene at many loci (polygenic inheritance) as well as the environment and how this can give rise to phenotypes that show continuous variation
6.17: Know how DNA can be amplified using the polymerase chain reaction (PCR)
This lesson describes the principles of in situ conservation and considers the benefits as well as the issues that surround this method. The PowerPoint and accompanying resources are part of the first lesson in a series of 2 which have been designed to cover the content of point 3.3 (iii) of the Edexcel A-level Biology B specification.
Hours of research have gone into the planning of this lesson to source interesting examples to increase the relevance of the biological content, and these include the Lizard National Nature Reserve in Cornwall, the Lake Télé Community reserve in the Republic of Congo and the marine conservation zone in the waters surrounding Tristan da Cunha. Students will learn how this form of active management conserves habitats and species in their natural environment, with the aim of minimising human impact whilst maintaining biodiversity. The main issues surrounding this method are discussed, including the fact that the impact of this conservation may not be significant if the population has lost much of its genetic diversity and that despite the management, the conditions that caused the species to become endangered may still be present. A number of quick quiz competitions are interspersed throughout the lesson to introduce key terms and values in a fun and memorable way and one of these challenges them to use their knowledge of famous scientists to reveal the surname, Fossey. Dian Fossey was an American conservationist and her years of study of the mountain gorillas is briefly discussed along with the final issue that wildlife reserves can draw poachers and tourists to the area, potentially disturbing the natural habitat.
