Differential cell centrifugation notes, A-level biology

One-page set of notes on differential ultracentrifugation to extract organelles, covering homogenization, the ice-cold, buffered, isotonic solution, extracting different organelles and links to recommended videos.

This set of notes is particularly targeted towards revising the practical come exam time-it doesn’t go into a detailed practical methodology for fractionation but gives exam-oriented explanation of how a centrifuge works, what a cold, buffered, isotonic solution is and why it’s needed.

These notes should be suitable for all major A-level courses, but they’re particularly designed to help AQA students taking into account points on the mark schemes for the 74011 specimen paper Q1, 74023 2018 Q5 and 74011 2018 Q7, which would be great for practice alongside these notes.