This detailed lesson describes how gene expression can be changed by epigenetic modification, which is important in ensuring cell differentiation. The PowerPoint and accompanying resources describe DNA methylation, histone modification, and non-coding RNA as methods of modification and are part of the final lesson in a series of 3 lessons that cover the content in point 7.2 of the Edexcel A-level biology B specification (Factors affecting gene expression).
HIV, atherosclerosis and cystic fibrosis are included in the lesson to demonstrate the application of this control of gene expression in real biological examples. Students are challenged throughout the lesson on their current understanding as well as their knowledge of previously covered topics which have links and the answers are embedded into the PowerPoint to allow them to assess their progress.
The other lessons in this series are uploaded and are titled “transcription factors” and “RNA splicing”.
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A bundle is a package of resources grouped together to teach a particular topic, or a series of lessons, in one place.
Topic 7: Modern genetics (Edexcel A-level biology B)
This bundle contains 7 detailed and engaging lessons which guide students through the key processes involved in modern genetics. Each lesson contains a variety of tasks, including exam-style questions (and answers), guided discussion points, and quick quiz rounds which will introduce the following content in topic 7 and challenge the students on their understanding: * Understand what is meant by the genome * The PCR can be used to amplify DNA samples * DNA samples can be used for gene sequencing and DNA profiling * The role of transcription factors * Post-transcription modification of mRNA * Gene expression can be changed by epigenetic modification * The differences between totipotent, pluripotent and multipotent stem cells * The formation of iPS cells and why their use is less controversial than embryonic cells * The production of recombinant DNA If you would like to view the quality of these lessons, then download the epigenetic modification lesson as this has been shared for free.
Topic 7.2: Factors affecting gene expression (Edexcel A-level biology B)
All 3 lessons included in this bundle are highly detailed and contain multiple biological examples to challenge the students to apply their understanding of a potentially difficult topic. A variety of tasks are embedded throughout the lessons and cover all of the content of topic 7.2 of the Edexcel A-level biology B specification (Factors affecting gene expression). If you would like to view the quality of the lessons before deciding on the bundle, then download the epigenetic modification lesson as this has been shared for free.
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