Epigenetics Activity: Modeling Epigenetic Gene Expression

Brief: In this Next Generation Science Standards Aligned activity, students review the steps of protein synthesis, and are introduced to the mechanics of epigenetic changes. Students predict how methylation affects gene expression, and model gene expression in six different scenarios in mice, using manipulatives that are included in the download. Finally, students contrast traditional gene expression from epigenetic expression, by answering conclusion questions.

A. NEXT GENERATION SCIENCE STANDARDS HEREIN
DCI’s: LS1.A Structure and Function
LS1.B Growth and Development
LS1.D Information Processing
LS3: Inheritance and Variation of Traits

Cross Cutting Concepts: Patterns, Cause and Effect, Systems and System Models, Structure and Function, Stability and Change

Scientific and Engineering Practices:
Analyzing and Interpreting Data, Developing and Using Models, Obtaining, Evaluating, and Communicating Information