pptx, 8.39 MB
pptx, 8.39 MB
docx, 13.14 KB
docx, 13.14 KB
docx, 13.83 KB
docx, 13.83 KB
docx, 14.12 KB
docx, 14.12 KB
docx, 12.73 KB
docx, 12.73 KB

This fully-resourced lesson describes the action of enzymes as biological catalysts and explains how their specificity is related to their 3D structure. The engaging PowerPoint and accompanying resources have been designed to cover points 2.10 (i) and (ii) of the Pearson Edexcel A-level Biology A specification but also introduces some examples of intracellular and extracellular enzymes to prepare students for the next lesson which covers 2.10 (iii).

The lesson has been specifically planned to tie in with related topics that were previously covered such as protein structure, globular proteins and intracellular enzymes. This prior knowledge is tested through a series of exam-style questions along with current understanding and mark schemes are included in the PowerPoint so that students can assess their answers.

Students will learn that enzymes are large globular proteins which contain an active site that consists of a small number of amino acids. Emil Fischer’s lock and key hypothesis is introduced to enable students to recognise that their specificity is the result of an active site that is complementary in shape to a single type of substrate. Time is taken to discuss key details such as the control of the shape of the active site by the tertiary structure of the protein. The induced-fit model is described so students can understand how the enzyme-susbtrate complex is stabilised and then students are challenged to order the sequence of events in an enzyme-controlled reaction.

The lesson finishes with a focus on ATP synthase and DNA polymerase so that students are aware of these important intracellular enzymes when learning about the details of respiration and DNA replication.

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Topic 2: Genes and Health (Pearson Edexcel SNAB)

Some of the key biological topics are covered in topic 2 of the Pearson Edexcel A-level Biology A (Salters Nuffield) course and include the transport of materials across cell membranes, DNA structure and replication, protein synthesis and monohybrid inheritance. In line with this, many hours of intricate planning have gone into the design of all of the 19 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked to immediately address misconceptions and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: * The properties of gas exchange surfaces in living organisms * Understand how the rate of diffusion is dependent on these properties and can be used in the calculation of the rate of diffusion by Fick's law * Adaptations of the mammalian lung for rapid gaseous exchange * Structure and properties of cell membranes * Simple and facilitated diffusion as methods of passive transport * The involvement of ATP and carrier proteins in active transport, endocytosis and exocytosis * The basic structure of mononucleotides * The structures of DNA and RNA * The process of protein synthesis * The roles of the template strand, mRNA and tRNA * The nature of the genetic code * A gene is a sequence of bases on DNA that codes for the amino acid sequence of a polypeptide * The basic structure of an amino acid * The formation of polypeptides and proteins * The primary, secondary, tertiary and quaternary structure of proteins * Globular and fibrous proteins using haemoglobin and collagen as examples * The mechanism of action and the specificity of enzymes * Enzymes are biological catalysts that reduce activation energy * The process of DNA replication * Errors in DNA replication can give rise to mutations * The meaning of key genetic terms * Patterns of inheritance, in the context of monohybrid inheritance * Understand how the expression of a gene mutation in people with cystic fibrosis impairs the functioning of the gaseous exchange, digestive and reproductive systems * Understand the uses and implications of genetic screening and prenatal testing Due to the detail included in each of these lessons, it is estimated that it will take in excess of 2 months of allocated teaching time to cover the content. If you would like to see the quality of the lessons, download the gas exchange surfaces, cell membranes, transcription, globular and fibrous proteins, monohybrid inheritance and cystic fibrosis lessons as these have been shared for free

£23.00

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