This fully-resourced lesson describes how DNA is replicated during interphase and explains why it is semi-conservative replication. Both the detailed PowerPoint and accompanying resources have been designed to cover the details of point 6.1 © of the CIE International A-level Biology specification
The main focus of this lesson is the roles of DNA helicase in breaking the hydrogen bonds between nucleotide bases and DNA polymerase incorporating the phosphorylated nucleotides into the sequence. Students are also introduced to DNA ligase to enable them to understand how this enzyme functions to join the nucleic acid fragments. Time is taken to explain key details such as the assembly of strands in the 5’-to-3’ direction so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure, phosphorylated nucleotides and hydrolysis reactions through a range of exam questions and answers are displayed so any misconceptions are quickly addressed. The main task of the lesson asks the students to use the information provided in the lesson to order the sequence of events in DNA replication before discussing how the presence of a conserved strand and a newly built strand in each new DNA molecule shows that it is semi-conservative.
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Topics 5 & 6: The mitotic cell cycle, nucleic acids & protein synthesis (CIE A-level Biology)
This lesson bundle contains 12 detailed lesson PowerPoints, which along with their accompanying resources, have been intricately planned to cover the majority of the content of topics 5 and 6 of the CIE A-level Biology specification. The cell cycle, mitosis and protein synthesis are topics that students tend to find difficult and therefore the planning focused on the inclusion of a wide range of tasks that would not only promote the retention of important information and secure knowledge but also maintain motivation and engagement. The tasks include exam-style questions with displayed mark schemes which challenge the students on their current understanding and prior knowledge, guided discussion points and quick quiz competitions which introduce key terms and values. The following specification points are covered by these 12 lessons: Topic 5 * The structure of a chromosome, limited to DNA, histone proteins, chromatids, centromere and telomere * The importance of mitosis in producing genetically identical cells, growth, cell replacement, repair of tissues and asexual reproduction * The cell cycle, including the G and S phases of interphase, mitosis and cytokinesis * Uncontrolled cell division and the formation of tumours * The behaviour of chromosomes in animal and plant cells in the mitotic cell cycle Topic 6 * The structure of nucleotides, including ATP * The structure of DNA and RNA * The semi-conservative replication of DNA during interphase * A polypeptide is coded for by a gene * Gene mutations can cause changes to the polypeptide sequence * The information in DNA is used during transcription and translation to construct polypeptides
£19.00
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Topic 6: Nucleic acids and protein synthesis (CIE International A-level Biology)
This is a fully-resourced lesson bundle, where the detailed and engaging PowerPoints and accompanying worksheets have been designed to cover the details of topic 6 of the CIE International A-level Biology specification which concerns the nucleic acids and protein synthesis. All 7 of the lessons include differentiated tasks to cater for all abilities of students whilst containing the detail to push them to the next level. The following specification points are covered within these lessons: * The structure of nucleotides * ATP as a phosphorylated nucleotide * The structure of DNA * The structure of mRNA, tRNA and rRNA * DNA replication * Genes and polypeptides * Gene mutations * Sickle cell anaemia * Transcription and translation Links are continually made throughout the lessons to previously-covered topics as well as to those which will be covered later in the AS course or during the second year If you would like to sample the quality of the lessons, download the semi-conservative replication and gene mutation lessons as these have been shared for free
£10.00
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Topic 6.1: Structure and replication of DNA (CIE International A-level Biology)
All 4 of the lessons included in this bundle are fully-resourced with differentiated tasks to cater for all abilities of students whilst containing the detail to push them to the next level. These lessons have been designed to cover the details of topic 6.1 of the CIE International A-level Biology specification which concerns the structure and replication of DNA The following specification points are covered within these lessons: * The structure of nucleotides * ATP as a phosphorylated nucleotide * The structure of DNA * The structure of mRNA, tRNA and rRNA * DNA replication Links are continually made throughout the lessons to previously-covered topics as well as to those which will be covered later in the AS course or during the second year If you would like to sample the quality of the lessons, download the semi-conservative replication lesson as this has been shared for free
£5.50
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Really helped break down the concepts for my students
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