Taxol
Subject: Chemistry
Age range: 16+
Resource type: Assessment and revision
This PowerPoint was planned as part of the Higher Level IB scheme of work on Medicinal Chemistry, and covers the necessary content for the D.7 section. It would also be suitable for other post-16 courses referring to Taxol or the use of chiral auxiliaries.
Included are the fully completed PowerPoint, a student version of the PowerPoint with sections to complete independently and some exam style questions, with markschemes.
Topics covered include:
- The Discovery of Paclitaxel
- Isolation of Taxol
- Structure of Taxol
- Semi-synthetic production of Taxol
- Clinical use of Taxol
- The use of chiral auxiliaries to produce one enantiomer of Taxol
- Confirmation of the purity of a single enantiomer drug
- Thalidomide
Included are the fully completed PowerPoint, a student version of the PowerPoint with sections to complete independently and some exam style questions, with markschemes.
Topics covered include:
- The Discovery of Paclitaxel
- Isolation of Taxol
- Structure of Taxol
- Semi-synthetic production of Taxol
- Clinical use of Taxol
- The use of chiral auxiliaries to produce one enantiomer of Taxol
- Confirmation of the purity of a single enantiomer drug
- Thalidomide
Get this resource as part of a bundle and save up to 32%
A bundle is a package of resources grouped together to teach a particular topic, or a series of lessons, in one place.
Bundle
Biochemistry and Medicinal Chemistry - Standard and Higher Level
These 18 PowerPoints were planned as part of the IB schemes of work on Biochemistry and Medicinal Chemistry, and covers the necessary content for the all of the Standard and Higher Level units. It would also be suitable for other post-16 courses. It includes 18 full PowerPoints, along with student versions to use as notes, which have spaces for the students to add in missing information and activities for them to complete. It also includes exam questions for practice or assessment purposes Topics covered are: Pharmaceutical Products and Drug Design \- Routes of drug administration \- Theraputic Effects of Drugs \- The Placebo Effect \- Side Effects \- Calculation of the Therapeutic Index \- The Therapeutic Window \- Bioavailability \- Tolerance and Addiction \- Drug Action \- Drug Development by both Drug Design and Drug Discovery Aspirin and Penicillin \- History of Aspirin \- Method of Producing Aspirin \- Calculating the % Yield of Aspirin produced from Salicyclic Acid \- Effects of Aspirin \- Soluble Aspirin \- Development of Penicillin \- Structure of Penicllin \- How Penicillin Works \- Antibiotic Resistance Opiates \- Morphine: Structure and action; side effects; withdrawal \- How opiates cross the blood-brain barrier \- Diamorphine pH regulation of the stomach \- The need for stomach acid \- pH calculations to determine the concentration of acid in the stomach \- Antacids: equations for their reactions with stomach acid; side effects; calculation of quantity of acid neutralised \- Regulation of acid production using both H2-histamine receptor blockers (Zantac) and proton pump inhibitors (Omeprazole and Esomeprazole) \- Acid-base buffers: definition and calculations \- Hydrogencarbonate and carbonate buffers Antivirals \- The differences between viruses and bacteria \- The structure of viruses \- How viruses reproduce and replicate \- How viruses are treated by interrupted stages of the replication process \- Oseltamivir and Zanamivir - structure and action \- HIV and AIDS \- Treatment of HIV and AIDS Environmental impacts of Biochemistry \- Effects of PACs on the environment \- Antibiotic Resistance \- Nuclear Waste (both LLW and HLW) \- Chlorinated solvent waste \- Supercritical fluid waste \- Green Chemistry \- Biotechnologies in Green Chemistry Taxol \- The Discovery of Paclitaxel \- Isolation of Taxol \- Structure of Taxol \- Semi-synthetic production of Taxol \- Clinical use of Taxol \- The use of chiral auxiliaries to produce one enantiomer of Taxol \- Confirmation of the purity of a single enantiomer drug \- Thalidomide Nuclear Medicine \- The use of radionuclides in medicine \- Types of ionising radiation \- Radiotherapy \- Radioactive Decay \- Targeted alpha therapy \- Boron neutron capture therapy \- Use of gamma emitters in radiotherapy \- Radiodiagnostics \- Positron Emission Tomography \- Use of Technetium-99m \- Half life and decay constant calculations \- Magnetic Resonance Imaging Drug Detection and Analysis \- Worked example of the identification of aspirin by NMR, IR and Mass Spectrometry \- Worked example of the identification of an unknown compound from NMR, IR and Mass Spectrometry \- Extraction and purification of organic products \- Worked example of hormone concentration using partition coefficients \- How polarity affects the partition coefficients \- Raoult´s Law \- Fractional Distillation \- Drug detection in sports \- Drug detection in forensic science \- Chemistry of breathalyzer tests \- HPLC and Gas chromatography Introduction to Biochemistry \- Metabolism \- Biochemical reactions in terms of oxidation and reduction \- Respiration \- Photosynthesis \- Hydrolysis and Condensation reactions Proteins \- 2 amino acids and their behaviour as zwitterions \- Gel electrophoresis \- Paper chromatography \- Peptides \- Hydrolysis of peptides \- Proteins - primary, secondary, tertiary and quaternary structures \- Acid-base properties of amino acids and proteins \- Acid-base buffers \- Enzymes \- Induced fit theory \- Non competitive and competitive inhibition \- The Michaelis-Menten equation \- Protein Assays Lipids \- Fatty acids \- Triglycerides \- Calculating the iodine number \- Hydrolysis of triglycerides \- Rancidity of fats \- Energy values of fats \- Phospholipids \- Steroids (including cholesterol) \- Sex hormones \- Anabolic steroids Carbohydrates \- Monosaccharides \- Reducing sugars \- Disaccharides \- Polysaccharides \- Starch, glycogen and cellulose Vitamins \- Preventing deficiencies \- Water and fat solubilities of vitamins \- Vitamin A \- Vitamin C \- Vitamin D \- Decomposition of vitamins Environmental Impacts of Biochemistry \- Xenobiotics \- Metabolism of xenobiotics \- DDT \- PCBs \- Heavy metal toxicity \- Pharmaceutically active compounds and detergents \- Host-guest complexes \- Polymers \- Green Chemistry Proteins \- 2 amino acids and their behaviour as zwitterions \- Gel electrophoresis \- Paper chromatography \- Peptides \- Hydrolysis of peptides \- Proteins - primary, secondary, tertiary and quaternary structures \- Acid-base properties of amino acids and proteins \- Acid-base buffers \- Enzymes \- Induced fit theory \- Non competitive and competitive inhibition \- The Michaelis-Menten equation \- Protein Assays Nucleic Acids \- Nucleic Acids \- Nitrogeneous Bases and Nucleotides \- ATP \- The structure of DNA \- DNA profiling \- DNA replication \- Transcription \- Genetic Engineering Biological Pigments \- Coloured compounds and biological pigments \- Carotenes \- Porphyrins \- Haemoglobin \- Factors affceting oxygen uptake in haemoglobin \- Foetal haemoglobin \- Cytochromes \- Chlorophyll \- Anthocyanins \- Melanin Stereochemistry in Biomolecules \- Stereoisomerism \- 2-amino acids \- Fischer and CORN projections \- Stereochemistry in Carbohydrates \- Stereochemistry cyclic forms of monosaccharides \- Stereochemistry in cellulose \- Stereochemistry in fatty acids \- Stereochemistry in retinal and vision chemistry
£34.00
Bundle
Medicinal Chemistry - Standard and Higher Level
This PowerPoint was planned as part of the IB scheme of work on Medicinal Chemistry, and covers the necessary content for the all of the Standard and Higher Level units. It would also be suitable for other post-16 courses. It includes 9 full PowerPoints, along with student versions to use as notes, which have spaces for the students to add in missing information and activities for them to complete. It also includes exam questions for practice or assessment purposes Topics covered are: Pharmaceutical Products and Drug Design \- Routes of drug administration \- Theraputic Effects of Drugs \- The Placebo Effect \- Side Effects \- Calculation of the Therapeutic Index \- The Therapeutic Window \- Bioavailability \- Tolerance and Addiction \- Drug Action \- Drug Development by both Drug Design and Drug Discovery Aspirin and Penicillin \- History of Aspirin \- Method of Producing Aspirin \- Calculating the % Yield of Aspirin produced from Salicyclic Acid \- Effects of Aspirin \- Soluble Aspirin \- Development of Penicillin \- Structure of Penicllin \- How Penicillin Works \- Antibiotic Resistance Opiates \- Morphine: Structure and action; side effects; withdrawal \- How opiates cross the blood-brain barrier \- Diamorphine pH regulation of the stomach \- The need for stomach acid \- pH calculations to determine the concentration of acid in the stomach \- Antacids: equations for their reactions with stomach acid; side effects; calculation of quantity of acid neutralised \- Regulation of acid production using both H2-histamine receptor blockers (Zantac) and proton pump inhibitors (Omeprazole and Esomeprazole) \- Acid-base buffers: definition and calculations \- Hydrogencarbonate and carbonate buffers Antivirals \- The differences between viruses and bacteria \- The structure of viruses \- How viruses reproduce and replicate \- How viruses are treated by interrupted stages of the replication process \- Oseltamivir and Zanamivir - structure and action \- HIV and AIDS \- Treatment of HIV and AIDS Environmental impacts of Biochemistry \- Effects of PACs on the environment \- Antibiotic Resistance \- Nuclear Waste (both LLW and HLW) \- Chlorinated solvent waste \- Supercritical fluid waste \- Green Chemistry \- Biotechnologies in Green Chemistry Taxol \- The Discovery of Paclitaxel \- Isolation of Taxol \- Structure of Taxol \- Semi-synthetic production of Taxol \- Clinical use of Taxol \- The use of chiral auxiliaries to produce one enantiomer of Taxol \- Confirmation of the purity of a single enantiomer drug \- Thalidomide Nuclear Medicine \- The use of radionuclides in medicine \- Types of ionising radiation \- Radiotherapy \- Radioactive Decay \- Targeted alpha therapy \- Boron neutron capture therapy \- Use of gamma emitters in radiotherapy \- Radiodiagnostics \- Positron Emission Tomography \- Use of Technetium-99m \- Half life and decay constant calculations \- Magnetic Resonance Imaging Drug Detection and Analysis \- Worked example of the identification of aspirin by NMR, IR and Mass Spectrometry \- Worked example of the identification of an unknown compound from NMR, IR and Mass Spectrometry \- Extraction and purification of organic products \- Worked example of hormone concentration using partition coefficients \- How polarity affects the partition coefficients \- Raoult´s Law \- Fractional Distillation \- Drug detection in sports \- Drug detection in forensic science \- Chemistry of breathalyzer tests \- HPLC and Gas chromatography
£16.00
Bundle
Medicinal Chemistry - Higher Level
This unit was planned as part of the Chemistry IB Option D - Medicinal Chemistry scheme of work, and covers all the topics at HL. It would also be suitable for other schemes of work. It includes 3 full PowerPoints, along with student versions to use as notes, which have spaces for the students to add in missing information and activities for them to complete. It also includes exam questions for practice or assessment purposes Topics covered are: Taxol \- The Discovery of Paclitaxel \- Isolation of Taxol \- Structure of Taxol \- Semi-synthetic production of Taxol \- Clinical use of Taxol \- The use of chiral auxiliaries to produce one enantiomer of Taxol \- Confirmation of the purity of a single enantiomer drug \- Thalidomide Nuclear Medicine \- The use of radionuclides in medicine \- Types of ionising radiation \- Radiotherapy \- Radioactive Decay \- Targeted alpha therapy \- Boron neutron capture therapy \- Use of gamma emitters in radiotherapy \- Radiodiagnostics \- Positron Emission Tomography \- Use of Technetium-99m \- Half life and decay constant calculations \- Magnetic Resonance Imaging Drug Detection and Analysis \- Worked example of the identification of aspirin by NMR, IR and Mass Spectrometry \- Worked example of the identification of an unknown compound from NMR, IR and Mass Spectrometry \- Extraction and purification of organic products \- Worked example of hormone concentration using partition coefficients \- How polarity affects the partition coefficients \- Raoult´s Law \- Fractional Distillation \- Drug detection in sports \- Drug detection in forensic science \- Chemistry of breathalyzer tests \- HPLC and Gas chromatography
£6.00
Something went wrong, please try again later.
This resource hasn't been reviewed yet
To ensure quality for our reviews, only customers who have purchased this resource can review it
Report this resourceto let us know if it violates our terms and conditions.
Our customer service team will review your report and will be in touch.
£2.50