The Discovery of Penicillin: video worksheets, differentiated.

A truly fascinating, entertaining, and informative account of the emergence of Penicillin. The drama, disaster, triumph, policy, politics, and CASH behind the scientific process.

Almroth Wright, WW 1 and the unsuitability of antiseptics, Alexander Fleming and St. Mary’s, lysozyme, his famous 1928 experiment. A brief history of penicillium before Fleming. Penicillin pharmacology and chemistry, mode of destroying gram-positive cell membranes. the Oxford interdisciplinary crew, Florey and Chain, Norman Heatley, Edward Penley Abraham. Funds from The Rockefeller Foundation. The mouse experiment. Gardner and Orr-Ewing. The sad case of Constable Albert Alexander. WW2 and USDA help. Deep tank fermentation. Crowfoot-Hodgkin and x-ray crystallography. Penicillin production, the economics of penicillin, OSRD funding. Penicillin praised in the print media. Overproduction and falling price. Problems with penicillin: allergies and resistance.

Find the film by searching YouTube’s Patrick Kelly channel for “Penicillin: From Fleming to the Pharmacy"

17 questions for the 29 min film. Differentiated! All versions look similar, but “B” version has **subtle clues. Excellent subtitles: scripted, not auto-generated miasma. Questions right up to the end, no slack time. Answer sheet. Very easy to mark. .doc & .pdf for all files. Link to film on all sheets