5.5 Antibodies NEW Year 12 Biology specification

This lesson plan/PowerPoint presentation provides all the activities (in one file!) to achieve the following learning objectives:

1) Describe the structure of an antibody and the functions of an antibody: Starter - Mini-white board drawing of an antibody; Activity 1: copy and complete the diagram of the antibody, challenge activity to add descriptions of parts of the antibody (answers included in the PowerPoint); Summary of antibody structure and animation to show hinge movement; Activity 2: antibody questions (answers provided in the PowerPoint); Activity 3: student worksheet (print hidden slide) describing the effects of antibodies (answers included), differentiation included with option for students to explain how each mechanism affects the immune system (answers provided in the PowerPoint); Activity 4: exam style question and mark scheme (included in the PowerPoint).

2) Explain the nature of a monoclonal antibody and how they are produced - Information slides on What are monoclonal antibodies, Production of mAbs, Activity 5: watch the video on monoclonal antibodies as a magic bullet then answer the questions (answers included in the PowerPoint, differentiation included with challenge question to evaluate use (answers included).

3) Summarise how monoclonal antibodies are used to target specific substances and cells - Activity 5 (as above); Activity 6 (pupil worksheet - hidden slide) Core Summary and Challenge (differentiation) Questions (answers provided).