CIE International A-level Biology TOPIC 3 REVISION (Enzymes)

This engaging REVISION lesson has been designed to cover the content of topic 3 (Enzymes) of the CIE International A-level Biology specification. A wide range of activities have been written into the lesson to engage the students whilst they assess their understanding of the topic content. All of the exam questions contain detailed answers which students can use to identify missed marks and quiz competitions are used, like FROM NUMBERS 2 LETTERS (shown in the cover image) to recall key concepts and check on the finer details.

The lesson has been planned to cover as much of the specification content as possible but the following sub-topics have received particular attention:

• Enzymes as globular proteins that act as biological catalysts
• Formation of the enzyme-substrate complex
• The lock and key theory and induced-fit hypothesis
• Competitive and non-competitive inhibitors
• The Michaelis-Menten constant
• The effect of changes in pH and temperature on the tertiary structure of the enzymes
• The immobilisation of enzymes using alginate

Time has been taken in the design to ensure that links to other topics are made. For example, when checking the knowledge of the denaturation of enzymes due to pH and temperature, the bonds found in the tertiary structure are recalled and considered in depth.