T Level Health, Core B further science concepts. Template adapted from Canva.com.
• functions of relevant component within the musculoskeletal system:
o skeleton – provides support, protection, attachment for muscles/ligaments, is a source of blood
production and stores minerals
o muscles – facilitate movement and provide support
o the sliding filament theory of musculoskeletal function in terms of thick and thin filaments sliding
over one another to bring about contraction and relaxation, and their working as antagonist pairs
B2.2 The process of muscle contraction:
• the stages of the sliding filament theory for muscle contraction:
o the role of calcium ions and adenosine diphosphate (ADP) in the formation of cross bridges
between actin and myosin filaments
o the role of ATP in breaking the cross bridge between the actin and myosin filaments
o the role of ATPase in restoring the myosin head to its normal position
o the repetition of this cycle leading to the shortening of the sarcomere
B2.4 The development, impact and management of muscular dystrophy disease:
• causes of the disease
• impact on systems within the body and on physical and mental health
• how common treatments relieve symptoms:
o steroids
o physiotherapy
o low impact exercise
o corrective surgery
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