Making monoclonal antibodies lesson created in accordance to the NEW AQA Specification (9-1). Designed for a higher ability SEPARATE (trilogy) class, although content can be adjusted to suit any ability. Includes: slide animations, embedded videos and practice questions with answers on slides.
NB: This resource is for separate science only
AQA spec link: 4.3.2.1
Relevant chapter: B6 Preventing and treating diseases. AQA Biology third edition textbook-Page 106-107
Specification requires students to know the following;
Students should be able to describe how monoclonal antibodies are produced.
Monoclonal antibodies are produced from a single clone of cells. The antibodies are specific to one binding site on one protein antigen and so are able to target a specific chemical or specific cells in the body.
They are produced by stimulating mouse lymphocytes to make a particular antibody. The lymphocytes are combined with a particular kind of tumour cell to make a cell called a hybridoma cell. The hybridoma cell can both divide and make the antibody. Single hybridoma cells are cloned to produce many identical cells that all produce the same antibody. A large amount of the antibody can be collected and purified.
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AQA Biology-SEPARATE topics PAPER 1 ONLY
Separate Sciences B5.3, B5.4, B5.10 & B5.11 B6.5 & B6.6
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AQA new specification-B6 Preventing and treating disease- Separate science bundlE
This bundle contains the content for SEPARATE science students. This bundle includes the B6 unit-Preventing and treating disease. All lessons have been done in accordance to the specification requirements. Videos have been embedded for ease of use (no internet connection required except for a BBC-drug trials video-URL provided), and printer friendly resources attached. Search the individual lessons for more information on the lesson content. Save 20% by purchasing this bundle :) Lesson 1-Vaccination Lesson 2-Antibiotics and painkillers (L1) (taught this over 2 lessons, both included in this resource pack). Lesson 3-Antibiotics and painkillers (L2) Lesson 4-Discovering drugs Lesson 5-Developing drugs Lesson 6-Making monoclonal antibodies Lesson 7-Uses of monoclonal antibodies
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