This lesson describes why a disease would be deemed to be an autoimmune disease and describes the mechanisms involved in a few examples. The PowerPoint and accompanying worksheets have been primarily designed to cover point 4.1.1 (k) of the OCR A-level Biology A specification, but this lesson can also be used to revise the content of modules 2 and 3 and the previous lessons in 4.1.1 through the range of activities included
The lesson begins with a challenge, where the students have to recognise diseases from descriptions and use the first letters of their names to form the term, autoimmune. In doing so, the students will immediately learn that rheumatoid arthritis, ulcerative colitis, type I diabetes mellitus, multiple sclerosis and myasthenia gravis are all examples of autoimmune diseases. The next part of the lesson focuses on the mechanism of these diseases where the immune system cells do not recognise the antigens (self-antigens) on the outside of the healthy cells, and therefore treats them as foreign antigens, resulting in the production of autoantibodies against proteins on these healthy cells and tissues. Key details of the autoimmune diseases stated above and lupus are described and links to previously covered topics as well as to future topics such as the nervous system are made. The students will be challenged by numerous exam-style questions, all of which have mark schemes embedded into the PowerPoint to allow for immediate assessment of progress.
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Module 4: Biodiversity, evolution and disease (OCR A-level Biology A)
The detailed content, exam-style questions, guided discussion points and quiz competitions that are found in each of the 16 paid lessons that are included in this bundle (as well as the 5 free lessons which are named at the bottom) cover the following specification points in module 4 of the OCR A-level Biology A specification: Module 4.1.1 * The different types of pathogen that can cause communicable diseases in plants and animals * The means of transmission of animal and plant communicable pathogens * The primary non-specific defences against pathogens in animals * The structure and mode of action of phagocytes * The structure, different roles and modes of action of B and T lymphocytes in the specific immune response * The primary and secondary immune responses * The structure and general functions of antibodies * An outline of the action of opsonins, agglutinins and anti-toxins * The differences between active and passive immunity, and between natural and artificial immunity * Autoimmune diseases * The principles of vaccination Module 4.2.1 * How biodiversity can be considered at different levels * The random and non-random sampling strategies that are carried out to measure the biodiversity of a habitat * How to measure species richness and species evenness * The use and interpretation of Simpson's Index of Diversity * How genetic biodiversity may be assessed * The ecological, economic and aesthetic reasons for maintaining biodiversity * In situ and ex situ methods of maintaining biodiversity * International and local conservation agreements made to protect species and habitats 4.2.2 * The biological classification of species * The binomial system of naming species and the advantage of such a system * The features used to classify organisms into the five kingdoms * The evidence that has led to new classification systems * The different types of variation * Using the standard deviation to measure the spread of a set of data * Using the Student's t-test to compare means of data values of two populations * Using the Spearman's rank correlation coefficient to consider the relationship of the data * The different types of adaptations to their environment * The mechanism by which natural selection can affect the characteristics of a population over time * How evolution in some species has an impact on human populations If you would like to get an idea of the quality of the lessons that are included in this bundle, then download the following five OCR A lessons which have been uploaded for free: Immunity & vaccinations Reasons for maintaining biodiversity Taxonomic hierarchy and the binomial naming system Adaptations and natural selection Transmission of animal and plant pathogens
Module 4.1.1: Communicable diseases, disease prevention and the immune system (OCR A-level Biology A)
This lesson bundle contains 8 detailed lesson PowerPoints and their accompanying resources and all of them have been planned at length to engage and motivate the students whilst covering the biological content of module 4.1.1 of the OCR A-level Biology A specification. The wide range of tasks which are contained with each of these lessons cover the following specification points: * The different types of pathogen that can cause communicable diseases in plants and animals * The means of transmission of animal and plant communicable pathogens * The primary non-specific defences against pathogens in animals * The structure and mode of action of phagocytes * The structure, different roles and modes of action of B and T lymphocytes in the specific immune response * The primary and secondary immune responses * The structure and general functions of antibodies * An outline of the action of opsonins, agglutinins and anti-toxins * The difference between active and passive immunity, and between natural and artificial immunity * Autoimmune diseases * The principles of vaccination and the role of vaccination programmes in the prevention of epidemics If you would like to sample the quality of the lessons in this bundle, then download the "Transmission of animal and plant pathogens" and "immunity & vaccinations" lessons as these have been uploaded for free
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