This lesson guides students through the calculation of mitotic indices and explores what a high value may indicate about the sampled tissue. The PowerPoint and accompanying resources have been planned to cover the content of point 3.16 of the Edexcel International A-level biology specification.
The lesson begins with a bit of fun, as the students are challenged to use three clues to identify three uses of the term index in biology. They’ll learn that the index of diversity is covered in a topic 4 lesson and that this lesson focuses on the mitotic index. The students are challenged on their knowledge of the mitotic cell cycle throughout the lesson and one of these questions is used to introduce the meaning of the index and the formula. A series of exam-style questions challenge them to apply their understanding, and the answers are embedded into the PowerPoint to enable the students to assess their progress. Moving forwards, the different meanings of high values are considered, including growing and repairing tissues, and then to explain how an elevated mitotic index can indicate that cell division has become uncontrolled which can lead to tumour formation.
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