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Isaac was an English Puritan divine. He was born one year after James VI of Scotland became James 1 of Scotland and England(1603-25).

He was brought up in a well known Roman Catholic family. Aged 17 he entered Brasenose College Oxford. He graduated in 1624 with a B.A. and ordained.

He became one of Charles 1 's itinerant preachers in Lancashire. He spent time in Garstang before he was selected by Lady Margaret Hoghton as vicar of Preston.

In 1641 he became a Presbyterian minister and was on the celebrated committee for the ejection of 'scandalous and ignorant ministers and schoolmasters during the Commonwealth. ’

He became caught up in the Civil War - Royalist v Parliamentarians (Charles II v Oliver Cromwell). Twice he was imprisoned by the Royalists. He tried to evade the political controversies of the time.
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In 1654, as a result of the Civil War, he left his great church in Preston and moved to Garstang. The 1662 Act of Uniformity saw him ejected, along with 2,000+ ministers, because he refused to conform ( See* Act of Uniformity and Great Ejection*)

His gentleness of character and earnest presentation of the gospel attached him to his congregation .

As a religious writer he had a vividness and freshness of imagination possessed by few of the puritan Nonconformist. His Looking unto Jesus held its own popular appreciation with the writings of John Bunyan.

Source
Wikipedia

See also sheet House of Stuart and First Interregnum

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