This fully-resourced lesson explains how an enzyme’s specificity is related to their 3D structure and enables them to act as biological catalysts. The engaging PowerPoint and accompanying resources have been designed to cover the first parts of specification point 1.4.2 and considers the details of Fischer’s lock and key hypothesis and Koshland’s induced-fit model to deepen student understanding of the mechanism of enzyme action
The lesson has been specifically planned to tie in with related topics that were previously covered such as protein structure and globular proteins. This prior knowledge is tested through a series of exam-style questions along with current understanding and mark schemes are included in the PowerPoint so that students can assess their answers.
Students will learn that enzymes are large globular proteins which contain an active site that consists of a small number of amino acids. Emil Fischer’s lock and key hypothesis is introduced to enable students to recognise that their specificity is the result of an active site that is complementary in shape to a single type of substrate. Time is taken to discuss key details such as the control of the shape of the active site by the tertiary structure of the protein. The induced-fit model is described so students can understand how the enzyme-susbtrate complex is stabilised and then students are challenged to order the sequence of events in an enzyme-controlled reaction.
The lesson finishes with a focus on ATP synthase and DNA polymerase so that students are aware of these important intracellular enzymes when learning about the details of respiration and DNA replication before they are challenged on their knowledge of carbohydrates, lipids and proteins from topics 1.2 - 1.4 as they have to recognise some extracellular digestive enzymes.
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Topic 1: Biological molecules (AQA A-level Biology)
The biological molecules topic is incredibly important, not just because it is found at the start of the course, but also because of its detailed content which must be well understood to promote success with the other 7 AQA A-level Biology topics. Many hours of intricate planning has gone into the design of all of the 20 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: * Monomers and polymers * Condensation and hydrolysis reactions * Common monosaccharides * Maltose, sucrose and lactose * The structure and functions of glycogen, starch and cellulose * Biochemical tests using Benedict's solution for reducing sugars and non-reducing sugars and iodine/potassium iodide for starch * The structure and properties of triglycerides and phospholipids * The emulsion test for lipids * The structure of amino acids * The formation of dipeptides and polypeptides * The levels of protein structure * The biuret test for proteins * Enzymes act as biological catalysts * The induced-fit model of enzyme action * The properties of an enzyme * The effect of temperature on the rate of an enzyme-controlled reaction * The effect of enzyme and substrate concentration on the rate of an enzyme-controlled reaction * The effect of competitive and non-competitive inhibitors on the rate of an enzyme-controlled reaction * The structure of DNA and RNA * The semi-conservative replication of DNA * ATP as the universal energy currency * The properties of water and its importance in Biology * Inorganic ions Due to the detail of each of these lessons, it is estimated that it will take in excess of 2 months of allocated teaching time to cover the content. If you would like to see the quality of the lessons, download the monomers and polymers, polysaccharides, triglycerides, dipeptides and polypeptides and inorganic ions lessons as these have been shared for free
£24.50
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Topic 1.4.2: Many proteins are enzymes (AQA A-level Biology)
Each of the five lessons included in this lesson bundle are fully-resourced and have been designed to engage and motivate the students whilst covering the following points that are detailed in topic 1.4.2 of the AQA A-level Biology specification: * Each enzyme lowers the activation energy of the reaction it catalyses * The induced-fit model of enzyme action * The specificity of enzymes * The effects of temperature, pH, enzyme concentration, substrate concentration and concentration of competitive and non-competitive inhibitors on the rate of enzyme-controlled reactions The lessons have been planned to come as a bundle and references are continually made to previous lessons in the topic to support the students in making the important links between structure, properties and actions of these globular proteins.
£8.00
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Topic 1.4: Proteins (AQA A-level Biology)
All 8 of the lessons that are included in this lesson bundle are highly detailed and will engage and motivate the students whilst covering the content of topic 1.4 of the AQA A-level Biology specification. With proteins playing critical roles in a wide range of living organisms, a clear understanding of the structure and functions of these biological molecules is important for all of the other topics. The following specification points are covered by the lessons in this bundle: * The general structure of an amino acid * A condensation reaction between two amino acids forms a peptide bond * The formation of dipeptides and polypeptides * The role of the tertiary structure bonds in the structure of a protein * The variety of functions of proteins in living organisms * The relationship between protein structure and function * The biuret test for proteins * Enzymes lower the activation energy of the reaction it catalyses * The induced fit model of enzyme action * The specificity of enzymes * The effects of temperature, pH, enzyme and substrate concentration and inhibitors on the rate of enzyme-controlled reactions If you would like to sample the quality of lessons in this bundle, then download the dipeptides & polypeptides lesson and the biuret test lesson as these have been uploaded for free
£9.00
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