This fully-resourced lesson explores sex-linkage and specifically the inheritance of sex-linked diseases in humans and then challenges the students to apply their knowledge to examples in other animals. The detailed PowerPoint and associated differentiated resources have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems involving sex-linkage.
Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final tasks of the lesson challenge the students to carry out a dihybrid cross that involves a sex-linked disease and an autosomal disease before applying their knowledge to a question about chickens and how the rate of feather production in chicks can be used to determine gender.
All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual markschemes to allow them to assess their progress and address any misconception
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Topic 16: Inherited change (CIE A-level Biology)
Meiosis, genetic inheritance and the control of gene expression are some of the harder topics on this A-level Biology course and all three are covered in topic 16 (Inherited change) of the CIE A-level Biology specification. The 10 lessons included in this bundle have been planned at length and contain a wide range of tasks that cover the detailed content whilst checking on understanding and key terms and values are introduced through engaging quiz competitions. The following topic 16 specification points are covered by these lessons: Topic 16.1 * The meaning of a homologous pair of chromosomes * The behaviour of chromosomes in animal and plant cells during meiosis * Genetic variation is caused by crossing over, random assortment and the random fusion of gametes at fertilisation Topic 16.2 * The meaning of key genetic terms * Using genetic diagrams to solve problems involving mohohybrid and dihybrid crosses, including those involving autosomal linkage, sex linkage, codominance, multiple alleles and gene interactions * Use the chi-squared test to test the significance of differences between observed and expected results * Gene mutations occur by substitution, deletion and insertion and may affect the phenotype Topic 16.3 * The genetic control of protein production in a prokaryote as shown by the lac operon * The function of transcription factors in gene expression in eukaryotes * Gibberellins and DELLA protein repressors If you would like to sample the quality of the lessons included in this bundle, then download the autosomal linkage and chi-squared test lessons as these have been uploaded for free
£15.00
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Topic 16.2 [b]: The roles of genes in determining the phenotype (CIE A-level Biology)
Each of the 5 lessons within this bundle are fully-resourced and cover the content of point (b) of topic 16.2 of the CIE A-level Biology specification which states that students should be able to use genetic diagrams to solve problems which involve the following: * monohybrid and dihybrid crosses * autosomal linkage * sex-linkage * codominance * multiple alleles * gene interactions Students are guided through the construction of the genetic diagrams for the inheritance of one or two genes and are shown how to analyse the phenotypic ratios to determine whether linkage has occurred or whether a gene interaction is involved. The wide range of activities which includes exam questions with visual mark schemes, differentiated tasks and quiz competitions will maintain engagement whilst providing the students with opportunities to assess their progress against the current topic
£6.50
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