A comprehensive four-page worksheet that deals with the physiology and function of the liver. This resource is aimed at advanced biology students and begins with a synoptic starter task that examines how blood flows through major body organs and the overall role of the liver in the mammalian circulatory system. The worksheet then moves on to look at gross anatomy of the liver and microscopic histology of the liver, covering details of the the liver lobules, bile canaliculi, sinusoids, hepatocytes and Kupffer cells.