This concise lesson describes the basic structure of an amino acid and introduces them as the monomers of polypeptides. The engaging PowerPoint has been designed to cover point 2.9 (i) of the Pearson Edexcel A-level Biology A specification and has been specifically written to lead into the next lesson on dipeptides and polypeptides. The lesson begins with a prior knowledge check, where the students have to use the 1st letters of 4 answers to uncover a key term. This 4-letter key term is gene and the lesson begins with this word because it is important for students to understand that these sequences of bases on DNA determine the specific sequence of amino acids in a polypeptide as detailed in specification point 2.8. Moving forwards, the students are given discussion time to work out that there are 64 different DNA triplets and will learn that these encode for the 20 amino acids that are common to all organisms. The main task of the lesson is an observational one, where students are given time to study the displayed formula of 4 amino acids. They are not allowed to draw anything during this time but will be challenged with 3 multiple choice questions at the end. This task has been designed to allow the students to visualise how the 20 amino acids share common features in an amine and an acid group. A quick quiz round introduces the R group and time is taken to explain how the structure of this side chain is the only structural difference, before cysteine is considered in greater detail due to the presence of sulfur atoms. Students are briefly introduced to disulfide bridges so they will recognise how particular bonds form between the R groups in the tertiary structure which is covered in the next lesson. The lesson concludes with one more quiz round called LINK TO THE FUTURE where the students will see the roles played by amino acids in the later part of the course such as translation and dipeptides.

This engaging lesson describes how chromosome mutations result in changes to the number or structure of chromosomes and focuses on Downs and Turner’s syndrome. The PowerPoint and accompanying resources have been designed to cover specification points 2.3 (vi) and (vii) as detailed in the Edexcel A-level Biology B specification. A human karyotype which has not been altered by a mutation is studied at the start of the lesson to allow students to recall the usual number of chromosomes as well as the sex chromosomes. They are then challenged to identify the differences when presented with the karyotypes of sufferers of Downs, Turner’s and Klinefelter’s syndrome. Students will learn that in the majority of cases, these conditions are the result of non-disjunction and having been assisted in the explanation of the outcome for Downs and Klinefelters, they have to form their own for Turner’s. The remainder of the lesson looks at other types of mutations, including translocation, and students will also see how whole sets of chromosomes can be duplicated in polyploidy.

This revision resource contains a concise yet informative PowerPoint (25 slides) and a worksheet that will enable the students to assess their understanding of the topic B4 (Enzymes) content of the CIE IGCSE Combined Science specification for examination in June and November 2020 and 2021. The range of exam questions (with explained answers), quick tasks and quiz competitions have been designed to cover as much content as possible but the following topics have received particular attention: Enzymes as biological catalysts that speed up reactions The binding of a substrate with the active site of an enzyme The effect of a changing pH on the activity of an enzyme The effect of a changing temperature on the activity of an enzyme Denaturation

This concise, engaging revision lesson has been designed to include activities that will motivate the students whilst they assess their understanding of topic B3 (Biological molecules) of the CIE IGCSE Combined Science specification. An understanding of biological molecules is fundamental to the understanding of a lot other Biology topics and this lesson has attempted to make the links between the different areas. The range of activities which include exam questions, quick tasks and quiz competitions have been written to cover as much of the content as possible but the following topics have received particular attention: The chemical elements in carbohydrates The formation of starch and glycogen from glucose The iodine test for starch Lipids are formed of fatty acids and glycerol Investigational skills The ethanol emulsion test for lipids This resource includes a PowerPoint (27 slides) and a worksheet with a task about the digestion of milk fat so students can recognise the components of lipids

This engaging lesson describes the relationship of the fibrous and globular structure of proteins to their function. The PowerPoint and accompanying resource have been primarily designed to cover specification point (j) as detailed in AS unit 1, topic 1 of the WJEC A-level Biology course but due to the detailed coverage of haemoglobin, the start of this lesson could also be used when teaching lessons that cover specification points in AS unit 2, topic 3 on adaptations for transport By the end of the lesson, students will be able to describe that the interactions of the hydrophobic and hydrophilic R groups results in different shapes which differ in their solubility in water and be able to explain the importance of this property with reference to the individual functions of proteins, specifically collagen and haemoglobin. They will also be able to name key individual details for each protein, such as haemoglobin being a conjugated protein and collagen having repeating units and being wound into a triple helix Extra time has gone into the planning of this lesson to ensure that links are continuously made to previous topics such as amino acids and the levels of protein structure as well as to upcoming topics

This concise lesson presentation and accompanying worksheet have been designed to cover the content of point 2.5 (h) of the WJEC GCSE Biology specification which states that students should understand the need to keep blood glucose levels within a constant range. Homeostasis is a running theme throughout the 2.5 topic so this lesson builds on knowledge from earlier topics to ensure that there is a deep understanding. The lesson begins by introducing glucose and a quiz competition will lead to the range 4 - 7, so that students can recognise that this is the set range within which this molecule’s concentration must be kept. Time is taken to look at some of the health problems that are associated with an increase in concentration above this upper limit and the general Biological knowledge of the students is tested with some questions. Moving forwards, the main task of the lesson involves a step by step guide through the stages in the response to a high blood glucose concentration and shows the students how the release of insulin leads to the uptake of glucose from the blood and a conversion to glycogen by the liver and muscle cells. The summary task at the end challenges the students to bring all of the information together to write a detailed description of this response and this activity is differentiated to aid those students who need extra assistance. This lesson has been designed for students studying the WJEC GCSE Biology course but could be used with A-level students who are beginning this topic and need to recall the key details.

This lesson explains how the polymerase chain reaction (PCR) is used to clone and amplify DNA fragments as part of the recombinant DNA technology process. The PowerPoint has been designed to cover point 19.1 © of the CIE International A-level Biology specification and there is a particular emphasis on the use of Taq polymerase as opposed to human DNA polymerase A quick quiz competition is used to introduce the PCR abbreviation before students are encouraged to discuss the possible identity of the enzyme involved and to recall the action of this enzyme. Students will learn that this reaction involves cyclical heating and cooling to a range of temperatures so the next part of this lesson focuses on each temperature and specifically the reasons behind the choice. Time is taken to examine the key points in detail, such as why Taq polymerase has to be used as it is not denatured at the high temperature as well as the involvement of the primers. This process is closely linked to other techniques like electrophoresis which is covered in a later lesson and ties are continuously made throughout the lesson

This engaging lesson describes the structures of virus particles and explains why viruses are described as acellular and non-living. The PowerPoint and accompanying resource are part of the second lesson in a series of 2 lessons which have been designed to cover the detail of specification point (b) in AS unit 1, topic 2 of the WJEC A-level Biology specification Details of the COVID-19 epidemic are included in the lesson to increase relevance and to help students to understand this biological topic in greater depth. They will understand that the lack of cell structures results in an acellular classification and the fact that it is unable to reproduce without a host is one of the additional reasons that renders it as non-living. The main focus of the lesson is the nucleic acid, the capsid and the attachment proteins that are present in these microorganisms and time is taken to explain how these structures are involved in the infection of a host cell. The lipid membrane is also introduced and links are made to the previous lessons on eukaryotic cells. The final section uses a version of BBC 1’s POINTLESS to introduce a number of viral diseases in animals and the use of a glycoprotein by HIV to attach to helper T cells is briefly introduced so students are prepared for the immunology option if taken

This is a concise, fast-paced lesson that has been designed to enable students to discover the key structural features of a synapse and be able to write accurate descriptions of the sequence of events that occur at these structures. The neurotransmitter involved is acetyl choline and therefore this is specifically a lesson about cholinergic synapses. The lesson begins by going through the terminology associated with synapses which includes pre-synaptic terminal or knob, synaptic cleft and post-synaptic neurone. Then time is taken to look at each of the two neurones and the structures found inside the terminal or on the membranes. The main task of the lesson involves a step by step guide through the sequence of events at the synapse. This guide has been written in a bullet point format and students are challenged to use the features they have met and their own Biological knowledge to complete each point. The final part of the lesson looks at how the enzyme acetylcholinesterase is involved in the breakdown and then how the neurotransmitter is re-formed using the ATP generated in the mitochondria This lesson is written for A-level students

This lesson has been designed to cover the content set out in specification point 2.5 (g) of the WJEC GCSE Biology specification which states that students should understand that hormones are chemical messengers which control many body functions. A wide range of activities have been written into the lesson with the aim of engaging and motivating the students whilst ensuring that the content is covered in detail. These activities include a number of quiz competitions which will challenge the students to identify an endocrine organ when presented with three organs as well as introducing them to the names of some of the hormones released by the pituitary gland. The following content is covered in this lesson: The location of the pituitary, adrenal and thyroid glands in the human body The location of the pancreas, ovaries and testes in the human body The hormones which are secreted by the endocrine glands The effects of the hormones on their target organs This lesson has been written for GCSE-aged students who are studying on the WJEC Biology course but it is suitable for younger students who are looking at this as one of the different organ systems

As the monomers of proteins, amino acids are extremely important and this lesson describes their structure and roles in organisms. The engaging PowerPoint has been designed to cover point (h) as detailed in AS unit 1, topic 1 of the WJEC A-level Biology specification and provides a clear introduction to the following lesson on the protein structures. The lesson begins with a prior knowledge check, where the students have to use the 1st letters of 4 answers to uncover a key term. This 4-letter key term is gene and the lesson begins with this word because it is important for students to understand that these sequences of bases on DNA determine the specific sequence of amino acids in a polypeptide. Moving forwards, students are given discussion time to work out that there are 64 different DNA triplets and will learn that these encode for the 20 amino acids that are common to all organisms. The main task of the lesson is an observational one, where students are given time to study the displayed formula of 4 amino acids. They are not allowed to draw anything during this time but will be challenged with 3 multiple choice questions at the end. This task has been designed to allow the students to visualise how the 20 amino acids share common features in an amine and an acid group. A quick quiz round introduces the R group and time is taken to explain how the structure of this side chain is the only structural difference, before cysteine is considered in greater detail due to the presence of sulfur atoms. Students are briefly introduced to disulfide bridges so they will recognise how particular bonds form between the R groups in the tertiary structure which is covered in the next lesson. One more quiz round called LINK TO THE FUTURE is used to demonstrate the range of roles played by amino acids in the later part of the course such as translation and mineral ions. The final part of the lesson considers challenges the students on their knowledge of hydrolysis reactions as they have to spot the errors in a passage about the breakdown of polypeptides and dipeptides.

This engaging lesson describes the relationship between the structure, properties and functions of phospholipids, focusing on its role in membranes. The PowerPoint has been designed to cover the second part of point (f) as detailed in AS unit 1, topic 1 of the WJEC A-level Biology specification and includes constant references to the previous lesson on triglycerides. The role of a phospholipid in a cell membrane provides the backbone to the whole lesson. A quick quiz round called FAMILY AFFAIR, challenges the students to use their knowledge of the structure of a triglyceride to identify the shared features in a phospholipid. This then allows the differences to be introduced, such as the presence of a phosphate group in place of the third fatty acid. Moving forwards, the students will learn that the two fatty acid tails are hydrophobic whilst the phosphate head is hydrophilic which leads into a key discussion point where the class has to consider how it is possible for the phospholipids to be arranged when both the inside and outside of a cell is an aqueous solution. The outcome of the discussion is the introduction of the bilayer which is critical for the lesson in AS unit 1, topic 3 on the fluid mosaic model. The final part of the lesson explains how both facilitated diffusion and active transport mean that proteins are found floating in the cell membrane and this also helps to briefly prepare the students for upcoming topic 3 lessons.

This lesson describes how the alveoli are adapted for gas exchange by diffusion between the air in the lungs and the blood capillaries. The PowerPoint and accompanying resource are part of the second lesson in a series of 2 which have been designed to cover the content of point 8.2 & 8.3 of the Edexcel GCSE Biology and Combined Science specifications. During the 1st lesson in this series, the students were shown how to calculate the surface area to volume ratio and so this lesson begins by challenging them to recall that the larger the organism, the smaller the ratio. This is done through the PLAY YOUR CARDS RIGHT format as shown in the cover picture, and leads into the key idea that complex multicellular organisms like humans have developed a range of different adaptations to increase this ratio at their exchange surfaces. Moving forwards, time is taken to consider and discuss how the following adaptations of the alveoli affect the rate of diffusion: large surface area lining of the alveoli consisting of a single layer of flattened cells maintenance of a steep concentration gradient Each feature is related to diffusion and current understanding and prior knowledge checks are used to allow the students to assess their progress and to challenge them to make links to other topics of the course. All exam questions have mark schemes embedded into the PowerPoint

This concise lesson has been designed to cover the content found in specification point 4.1.3.2 (Osmosis) of topic 1 of the AQA GCSE Biology & Combined Science specifications. This resource contains an engaging PowerPoint (23 slides) and accompanying worksheets, some of which have been differentiated to help students of different abilities to take on the task at hand. The lesson begins with the introduction of the term, osmosis, and then students are challenged to use their knowledge of diffusion to write a definition for this method of movement of water molecules. A series of questions which check understanding are included at this early point of the lesson to ensure that the key points are known and any misconceptions are quickly addressed. Students are also challenged with an application question as these can often cause them the most problems. Moving forwards, the rest of the lesson focuses on an osmosis investigation. Scientific skills are tested during a range of tasks as well as numerical skills and guidance is given on how to calculate percentage change. As stated at the top, this lesson has been designed for GCSE-aged students who are studying the AQA GCSE Biology course, but can be used with younger students who are keen to learn about osmosis

This lesson introduces and explains the meaning of 11 key terms associated with the genetic inheritance topic. The PowerPoint and accompanying resources have been designed to cover point 6.1.6 of the AQA GCSE Combined Science specification and include explanations of genome, chromosome, gene, allele, genotype, homozygous, heterozygous, phenotype, dominant, recessive and gamete. The key term, genome, was met earlier in topic 6 so the lesson begins with a knowledge retrieval with the definition for this term. As the genome is the entire DNA of an organism, the next task challenges the students to identify three errors in a passage about DNA. This challenges their recall of the structure of this chemical as a double helix, its location in an eukaryotic cell in the nucleus and an understanding that the gene codes for the sequence of amino acids in a specific protein. This leads into discussions about chromosomes and genes and time is taken to explain that homologous chromosomes have the same genes at the exact same gene loci. The students will learn that alternative forms of the gene (alleles) can be found at these loci and that these structures explain the differences in inherited characteristics. Moving forwards, the main section of the lesson describes the link between the dominant and recessive alleles, homozygous and heterozygous genotypes, and the physical expression as the phenotype. The final key term is gamete, and the students are challenged to recognise a definition for this term using their knowledge of meiosis. Two progress and understanding checks complete the lesson and check on the students’ ability to recognise and write definitions for these 11 terms and to use them accurately in a written description

This lesson uses a step-by-step guide to describe the role of gibberellins in the germination of barley. The PowerPoint and accompanying resource have been planned to cover point (3) of topic 15.2 of the CIE A-level biology specification (for assessment in 2025 - 27). The lesson begins with a challenge, where the students must identify the term, germination, from a series of clues. They will learn that this is the development of a plant from a seed following a period of dormancy and involves gibberellins. A quick quiz round is then used to introduce the embryo, endosperm and aleurone layer in the structure of a barley seed. The process of seed germination can be divided into a sequence of 9 events and the main task of the lesson challenges the students to order these 9 events. However, this task has an extra level of difficulty as two of the events have been missed out, so the students must use the clues to predict the key biological processes in these events.

This lesson describes how mutations to the genes that control mitosis can lead to uncontrolled cell division and the formation of cancerous tumours. The PowerPoint and accompanying resources are part of the final lesson in a series of 3 lessons which have been planned to cover the content of topic 2.2 (All cells arise from other cells) of the AQA A-level biology specification. The first 2 lessons in this series of lessons described the events of the mitotic cell cycle and the calculation of the mitotic index and interpretation of the calculated value, and this lesson has been designed to check on their understanding and to build on the existing knowledge. The lesson begins with a task using numbers from biology to reveal the term, controlled, which leads into the recognition that mitosis is a controlled process that’s controlled by genes. Moving forwards, the students will understand that mutations to these genes and the formation of alleles can cause the cell division to become uncontrolled and this leads to the formation of tumours. Students will learn that there are benign and malignant tumours and that the latter are cancerous. The topic of tumours is covered in more detail in topic 8, but the key details are introduced here. The example of the BRCA genes is used to describe treatments that aim to control the rate of cell division and the importance of diagnosing cancer early to try to prevent the spread to other tissues.

This lesson outlines the role of sensory receptor cells in the detection of stimuli and describes the generation of an impulse in a sensory neurone. The PowerPoint and accompanying resources have been planned to cover points 4 & 5 of topic 15.1 of the CIE A-level biology specification (for assessment in 2025-27) and use the chemoreceptors in taste buds as the example to describe the sequence of events. The previous lesson described the structure and function of sensory and motor neurones and the 1st task challenges the students on their recall of this content to generate the key term, stimuli. Students will recall that this is a change in the environment and that sensory receptor cells are responsible for the detection of these changes. A quick quiz round called “REACT” introduces several stimuli and then students will learn that sensory receptor cells act as specialised transducers by converting one form of energy into electrical energy. Students are introduced to key terms which will be covered in greater detail in upcoming lessons, including resting potential and depolarisation, and they will be challenged to use these in the final task of the lesson. The Pacinian corpuscle is shown and its role in the detection of pressure described, including how sodium ions enter the generator region of the sensory neurone. The remainder of the lesson describes the sequence of events that result in the conduction of an action potential along a sensory neurone after the detection of new chemicals by chemoreceptors in taste buds.

This lesson describes how the leaching of fertilisers into waterways leads to eutrophication and explores the adverse effects on those habitats. The PowerPoint and accompanying resources have been designed to cover the content of topic 5 point § of A2 unit 3 as set out in the WJEC A-level biology specification. The lesson begins with a quick task which requires the students to use their knowledge of biological numbers to flow through the alphabet and this reveals the key term, leaching. This leads into a step-by-step guide through the stages of eutrophication, with descriptions of the algal bloom, restriction of light to aquatic plants, death and decomposition, and the reduction in the dissolved oxygen concentration. Prior knowledge checks are used throughout to support the understanding, and all answers are embedded into the PowerPoint to allow students to assess their progress.

This lesson uses a 10 question multiple-choice assessment to provide students with the opportunity to assess their knowledge of neuronal communication. Module 5.1.3 of the OCR A-level biology A specification covers the role of mammalian sensory receptors, the structure and function of neurones, the generation and transmission of nerve impulses and the structure and roles of synapses and these 10 questions attempt to challenge their overall understanding of this content. The lesson also includes a PowerPoint with the answers to the questions and also further understanding checks to challenge knowledge not directly covered by the multiple-choice assessment. There are also some prior knowledge checks and links to the future.