This is a concise, fast-paced lesson which guides students through the critical skills needed to calculate the atom economy of a chemical reaction. It has been designed for GCSE students and focuses on the calculation as well as interpreting the final value. In order to calculate the mass of the desired product and other products, students have to be able to calculate the relative formula mass - therefore time is taken to revisit these skills and worked examples are used with this and the actual calculations to enable the students to visualise how they should set their work out. The lesson finishes with some progress check questions where students are challenged to state which of four chemical reactions has the highest atom economy. This lesson could be taught in combination with the percentage yield topic and an accompanying lesson on that calculation is available on this site.

This detailed lesson looks at the structure of the mitochondrion and explains how the specific features allow the stages of aerobic respiration to take place in this organelle. The engaging PowerPoint and accompanying resource have been designed to cover point 5.2.2 (b) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the inner and outer mitochondrial membranes, cristae, matrix and mitochondrial DNA. The lesson begins with a version of “GUESS WHO” where students have to use a series of structural clues to whittle the 6 organelles down to just 1 - the mitochondrion. Moving forwards, the key components of the organelle are identified on a diagram. Students are introduced to the stages of respiration so that they can make a link to the parts of the cell and the mitochondria where each stage occurs. Students will learn that the presence of decarboxylase and dehydrogenase enzymes in the matrix along with coenzymes and oxaloacetate allows the Link reaction and the Krebs cycle to run. Finally, time is taken to introduce the electron transport chain and the enzyme, ATP synthase, so that students can begin to understand how the flow of protons across the inner membrane results in the production of ATP. This lesson has been designed to tie in with the other uploaded lessons on the stages of respiration.

This detailed lesson describes and explains the blood pressure changes that occur during systole and diastole of the cardiac cycle. The PowerPoint and accompanying resource have been designed to cover point 8.2 © of the CIE International A-level Biology specification. The start of the lesson introduces the cardiac cycle as well as the key term systole, so that students can immediately recognise that the three stages of the cycle are atrial and ventricular systole followed by diastole. Students are challenged on their prior knowledge of the structure of the heart as they have to name and state the function of an atrioventricular and semi-lunar valve from an internal diagram. This leads into the key point that pressure changes in the chambers and the major arteries results in the opening and closing of these sets of valves. Students are given a description of the pressure change that results in the opening of the AV valves and shown where this would be found on the graph detailing the pressure changes of the cardiac cycle. They then have to use this as a guide to write descriptions for the closing of the AV valve and the opening and closing of the semi-lunar valves and to locate these on the graph. By providing the students with this graph, the rest of the lesson can focus on explaining how these changes come about. Students have to use their current and prior knowledge of the chambers and blood vessels to write 4 descriptions that cover the cardiac cycle. The final part of the lesson covers the changes in the volume of the ventricle. This lesson has been written to tie in with the other uploaded lessons on the heart as detailed in topic 8.2

This fully-resourced lesson describes the inheritance of genes with loci on the X chromosomes and considers biological examples. The detailed PowerPoint and accompanying resources have been designed to cover point 2.15 (ii) of the Edexcel International A-level specification and focuses on the inheritance of red-green colour blindness and haemophilia in humans Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final task of the lesson challenge the students to apply their knowledge to an exam question about chickens and how the rate of feather production in chicks can be used to determine gender. All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual mark schemes to allow them to assess their progress and address any misconceptions

This is a highly engaging and detailed lesson which looks at the physiological and behavioural responses involved in temperature control in endotherms and therefore covers specification point 5.1.1 (d) of the OCR A-level Biology A specification. A wide range of activities have been written into the PowerPoint and accompanying worksheets so that students remain motivated throughout and take a genuine interest in the content. Understanding checks allow the students to assess their progress whilst the prior knowledge checks on topics such as enzymes and denaturation demonstrate the importance of being able to make connections and links between topics from across the specification. In addition to these checks, quiz competitions like HAVE an EFFECT which is shown in the cover image are used to introduce key terms and values in a fun and memorable way. The lesson begins by introducing the key term, endotherm, and challenging students to use their prior knowledge and understanding of terminology to suggest what this reveals about an organism. Moving forwards, students will learn how the heat generated by metabolic reactions is used as a source of internal heat. The main part of the lesson focuses on thermoregulation in humans (mammals) and time is taken to focus on the key components, namely the sensory receptors, the thermoregulatory centre in the hypothalamus and the responses brought about by the skin. The important details of why the transfer of heat energy between the body and the environment actually leads to a decrease in temperature are explored and discussed at length to ensure understanding is complete. Students are challenged to write a detailed description of how the body detects and responds to a fall in body temperature and this task is differentiated for those students who need some extra assistance. The peripheral thermoreceptors are introduced and this leads into the final section of the lesson that considers behavioural responses in humans and other animals. This lesson has been designed for A-level students studying the OCR A-level Biology A course

A resourced lesson which uses a concise lesson presentation (18 slides) and a differentiated diagram to guide students through the method of blood clotting. This lesson has been designed for students studying GCSE (14 - 16 year olds in the UK) and this is reflected in the appropriate detail where only the involvement of fibrin needs to be known. Students are shown how blood clotting is a cascade effect where one event leads on to the next.

This is a concise, fast-paced lesson that introduces students to addition polymers and guides them through drawing displayed formulae to represent both the monomers and polymers involved in these reactions. Students will learn the conditions needed for these reactions and that the polymers produced by addition reactions are the only products. The main part of the lesson involves a step by step guide to show students how to draw displayed formulae. Hints are given throughout the process so that students can remember the key ideas and are able to represent these substances accurately. A number of progress checks have been written into the lesson so that students can assess their understanding any misconceptions can be addressed. This lesson has been written for GCSE students

An engaging lesson presentation which looks at the two types of animal stem cells, exploring their important differences and briefly looking at their potential uses in medicine. The lesson begins by looking at the meaning of the term differentiation and then challenging students to draw a simple conclusion once they know that stems cells are undifferentiated cells. Time is taken to look into this part of the knowledge in depth but then students are given the key points which must be understood for them to move forwards. Students are told that there are two types of animal stem cells before a quiz competition is used to get them to predict which one of the two is being described by the clues. The answers to the competition then have to be used to write a summary passage about the two types. Students are also told that stem cells exist in plants in the form of meristem cells. Finally, Parkinson’s disease and Diabetes mellitus Type I are used as examples of conditions that could be potentially treated with stem cells.

This is a fun and engaging lesson that uses a range of quick competitions and tasks to ensure that the students recognisethe electrical symbols for the essential components and can describe the functions for each of these. Competitions such as SNAP and SAY WHAT YOU SEE will introduce the students to the components and their symbols. This lesson has been written for GCSE students and looks to build on what they should know from KS3 - however, it could be used with higher ability students at that level.

This fully-resourced lesson explores the contributions of chromosome mutations to genetic variation. The engaging PowerPoint and accompanying worksheets have been designed and written to cover the part of point 6.1.2 (a) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the contribution of genetic factors to phenotypic variation Over the course of the lesson, students will encounter a number of chromosome mutations and see the conditions which they cause. Time is taken to look at non-disjunction and how this can result in Down, Turner’s and Klinefelter’s syndromes. Students are guided through a description of the formation of gametes and zygotes with abnormal numbers of chromosomes before being challenged to describe the formation of a zygote with Turner’s syndrome. Moving forwards, translocation and polyploidy are also discussed. Progress checks are written into the lesson at regular intervals, that not only check the learning from this lesson but also from related topics (such as meiosis) and this enables the students to constantly assess their understanding.

This fully-resourced lesson looks at the effects of nervous mechanisms on the heart rate. The engaging and detailed PowerPoint and accompanying resources have been designed to cover the part of point 5.1.5 (k) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the control of the heart rate by the cardiovascular centre in the medulla oblongata This lesson begins with a prior knowledge check where students have to identify and correct any errors in a passage about the conduction system of the heart. This allows the SAN to be recalled as this structure play an important role as the effector in this control system. Moving forwards, the three key parts of a control system are recalled as the next part of the lesson will specifically look at the range of sensory receptors, the coordination centre and the effector. Students are introduced to chemoreceptors and baroreceptors and time is taken to ensure that the understanding of the stimuli detected by these receptors is complete and that they recognise the result is the conduction of an impulse along a neurone to the brain. A quick quiz is used to introduce the medulla oblongata as the location of the cardiovascular centre. The communication between this centre and the SAN through the autonomic nervous system can be poorly understood so detailed explanations are provided and the sympathetic and parasympathetic divisions compared. The final task challenges the students to demonstrate and apply their understanding by writing a detailed description of the control and this task has been differentiated three ways to allow differing abilities to access the work

This clear and concise lesson explores the importance of coenzymes in cellular respiration as detailed in point 5.2.2 (f) of the OCR A-level Biology A specification. Students encountered coenzymes in module 2.1.4 as well as looking at the roles of NAD, CoA and FAD whilst learning about glycolysis, the link reaction and Krebs cycle earlier in this module. Therefore this lesson was designed to check on their understanding of the importance of these roles and goes on to explain how the transport of the protons and electrons to the mitochondrial cristae is key for the production of ATP. This lesson has been written to tie in with the other uploaded lessons in module 5.2.2 which include the mitochondria, glycolysis, the link reaction and the Krebs cycle

This fully-resourced lesson looks at the internal and external structure of the mammalian heart and uses the human heart to represent this anatomy. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 3.1.2 (e) (i) of the OCR A-level Biology A specification As this topic was covered at GCSE, the lesson has been planned to build on this prior knowledge whilst adding the key details which will enable students to provide A-level standard answers. The primary focus is the identification of the different structures of the heart but it also challenges their ability to recognise the important relationship to function. For example, time is taken to ensure that students can explain why the atrial walls are thinner than the ventricular walls and why the right ventricle has a thinner wall than the left ventricle. Opportunities are taken throughout the lesson to link this topic to the others found in topic 3.1.2 including those which have already been covered like circulatory systems as well as those which are upcoming such as the initiation of heart action. There is also an application question where students have to explain why a hole in the ventricular septum would need to be repaired if it doesn’t naturally close over time.

This fully-resourced lesson describes the relationship between the structure, properties and functions of triglycerides in living organisms. The engaging PowerPoint and accompanying worksheets have been designed to be the first lesson in a series of two that cover specification points 2.1.2 (h), (i) & (j) of the OCR A-level Biology A course and the lesson contains numerous references to relevant future topics such as the importance of the myelin sheath for the conduction of an electrical impulse. The lesson begins with a focus on the basic structure and roles of lipids, including the elements that are found in this biological molecule and some of the places in living organisms where they are found. Moving forwards, the students are challenged to recall the structure of the carbohydrates from earlier in the sub-module so that the structure of a triglyceride can be introduced. Students will learn that this macromolecule is formed from one glycerol molecule and three fatty acids and have to use their understanding of condensation reactions to draw the final structure. Time is taken to look at the difference in structure and properties of saturated and unsaturated fatty acids and students will be able to identify one from the other when presented with a molecular formula. The final part of the lesson explores how the various properties of a triglyceride mean that it has numerous roles in organisms including that of an energy store and source and as an insulator of heat and electricity.

This lesson describes how to use and manipulate the magnification formula to calculate the magnification or the actual size in a range of units. The PowerPoint and accompanying resources have been designed to cover point 2.1.1 (e) of the OCR A-level Biology A specification and contains a number of quiz rounds as part of the competition that runs throughout all of the module 2.1.1 lessons The students are likely to have met the magnification formula at GCSE so this lesson has been written to build on that knowledge and to support them with more difficult questions when they have to calculate actual size without directly being given the magnification. A step by step guide is used to walk the students through the methodology and useful tips are provided. Students could be asked to calculate the actual size in millimetres, micrometres, nanometres or picometres so time is taken to ensure that they can convert between one and another.

This fully-resourced lesson describes the ultrastructure of a prokaryotic cell and the function of the structures found in these cells. The engaging PowerPoint and accompanying resources have been designed to cover specification point 3.5 (i) & (ii) as detailed in the Edexcel International A-level Biology specification and also compares these cells against the eukaryotic cells that were met in the previous lesson. A clear understanding of terminology is important for A-level Biology so this lesson begins with a challenge, where the students have to recognise a prefix that they believe translates as before or in front of . This leads into the discovery of the meaning of prokaryote as before nucleus and this acts to remind students that these types of cell lack this cell structure. Links to the previous lessons on the eukaryotic cells are made throughout the lesson and at this particular point, the students are asked to work out why the DNA would be described as naked and to state where it will be found in the cell. Moving forwards, the students will discover that these cells also lack membrane bound organelles and a quick quiz competition challenges them to identify the specific structure that is absent from just a single word. In addition to the naked DNA, students will learn that there are also ribosomes in the cytoplasm and will discover that these are smaller than those found in the cytoplasm of an eukaryotic cell (but the same size as those in chloroplasts and mitochondria). The remainder of the lesson focuses on the composition of the cell wall, the additional features of prokaryotic cells such as plasmids and there is also the introduction of binary fission as the mechanism by which these organisms reproduce

This lesson describes the structure and mode of action of phagocytes and focuses on the neutrophils and macrophages as APCs. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 4.1.1 (e) [i] of the OCR A-level Biology A specification and also includes an introduction to antigen-presentation so that the students are prepared for the next lesson on the specific immune response At the start of the lesson, the students are challenged to recall that cytosis is a suffix associated with transport mechanisms and this introduces phagocytosis as a form of endocytosis which takes in pathogens and foreign particles. This emphasis on key terminology runs throughout the course of the lesson and students are encouraged to consider how the start or end of a word can be used to determine meaning. The process of phagocytosis is then split into 5 key steps and time is taken to discuss the role of opsonins as well as the fusion of lysosomes and the release of lysozymes. A series of application questions are used to challenge the students on their ability to make links to related topics including an understanding of how the hydrolysis of the peptidoglycan wall of a bacteria results in lysis. Students will be able to distinguish between neutrophils and monocytes from a diagram and at this point, the role of macrophages and dendritic cells as antigen-presenting cells is described so that it can be used in the next lesson. The lesson concludes with a brief introduction to lymphocytes so that initial links between phagocytosis and the specific immune response is made.

An informative lesson presentation (26 slides) that shows students how to convert between numbers and standard form (and the other way) so they are able to understand when these are used in Science questions. The lesson begins by guiding them through how to change numbers to standard form and explains when a power of 10 that is positive will be achieved and when it will be negative. Students are given the opportunity to see these used in a Science question and there is a cross-subject link as they are also required to convert between units. A number of competitions are used near the end of the lesson to maintain motivation and to allow the students to check their progress in a fun way This lesson has been designed for GCSE students but is suitable for KS3

This fully-resourced lesson looks at the type of circulatory system found in a mammal (double, closed) and considers how the pulmonary circulation differs from the systemic circulation. The engaging PowerPoint and accompanying resources have been designed to cover point 3.1.2 (b) of the OCR A-level Biology A specification The lesson begins with a focus on the meaning of a double circulatory system and checks that students are clear in the understanding that the blood passes through the heart twice per cycle of the body. Beginning with the pulmonary circulation, students will recall that the pulmonary artery carries the blood from the right ventricle to the lungs. An opportunity is taken at this point to check on their knowledge of inhalation and the respiratory system as well as the gas exchange between the alveoli and the capillary bed. A quick quiz is used to introduce arterioles and students will learn that these blood vessels play a crucial role in the changes in blood pressure that prevent the capillaries from damage. When looking at the systemic circulation, time is taken to look at the coronary arteries and renal artery as students have to be aware of these vessels in addition to the ones associated with the heart. In the final part of the lesson, students are challenged to explain how the structure of the heart generates a higher pressure in the systemic circulation and then to explain why the differing pressures are necessary. This lesson has been written to tie in with the other uploaded lessons from topic 3.1.2 (transport in animals)

An engaging lesson presentation (33 slides) that looks at the key details of asexual reproduction, examines the process in bacteria and plants and also considers the advantages and disadvantages. The lesson begins by challenging the students to discuss whether reproduction always requires two (parents). Students will see how only one parent is involved in this type of reproduction and will focus on how it takes place in bacteria. Moving forwards, students will be introduced to the methods of runners, bulbs and tubers in plants. By making connections to natural selection, students will be challenged to think about the benefits of asexual reproduction. There are regular progress checks throughout the lesson so that students can assess their understanding. This lesson is suitable for both KS3 and GCSE students