A series of six worksheets aimed at advanced biology students, this comprehensive resource provides a series of exercises that discuss the role and properties of haemoglobin. This resource includes a starter task for initial discussion on the behaviour of haemoglobin followed by more detailed discussion on the nature of the oxyhaemoglobin dissociation curve, Bohr shift, haemoglobin in other organisms and comparison of adult haemoglobin to foetal haemoglobin and myoglobin. Key words: haemoglobin, Bohr shift, oxyhaemoglobin, dissociation, oxygen, carbon dioxide, chloride shift, respiration, partial pressure, myoglobin

Worksheet that discusses how plasmids from bacteria are recombined with donor DNA. The worksheet illustrates how screening for bacteria that have successfully taken up modified plasmids works, along with the use of antibiotic resistant marker genes.

A worksheet aimed at advanced biology students that introduces the concept of disease. The worksheet covers categories of disease (e.g. infectious, lifestyle, inherited), examples of disease, mechanisms of infectious disease, interfaces for pathogens and interpretation of epidemiological patterns.

A detailed worksheet/activity that introduces the idea of calorimetry as a means of measuring the energy value of foods. The worksheet provides space for initial readings and subsequent calculations. There is discussion of how to calculate and use specific heat capacity followed by questions on the limitations of this investigation. Finally, as extension material, the worksheet has an exercise on spearman rank statistical test to see whether there is a link between the amount of energy in food and the fat content. Suitable for use with A-Level biology students as a part of a practical investigation during any topic on energy transfer, food chains, etc. Key words: Energy, food chains, specific heat capacity, spearman rank, statistical test, fat, combustion, burning, calorimeter

A worksheet aimed at advanced biology students, this comprehensive set of worksheets can effectively be used to introduce the concept of homeostasis (focusing on negative feedback mechanisms and the need to keep a steady state) and thermoregulation. Students can work their way through each section of the worksheet before a class discussion to check understanding - for some sections a teacher may decide to lead on an explanation before using the worksheet exercises as a way of checking understanding. Key words: homeostasis, negative feedback, thermoregulation, sweating, vasoconstriction, vasodilation, piloerection, shivering

A resource aimed at advanced biology students, this comprehensive four-page worksheet covers an overview of kidney anatomy, blood vessel arrangements, filtration at the glomerulus and interpretation of micrograph images of podocytes at the renal capsule. Key words: kidney, transplant, dialysis, glomerulus, filtration, proximal convoluted tubule, distal convoluted tubule, loop of Henle, collecting duct, aldosterone, anti diuretic hormone, osmosis, reuptake, hydrostatic pressure

A worksheet (three different versions are included) that is aimed at Advanced Biology students and which discusses how heart rate is controlled by both the brain and hormones. Each worksheet has a slightly different emphasis and can be adapted to the needs of your class. Topics covered include: 1. How the heart is innervated by the brain 2. The nature of sympathetic and parasympathetic control 3. The involvement of hormones in controlling heart rate 4. The action of neurotransmitters at synapses 5. The action of drugs that can affect the cardiac cycle 6. How chemoreceptors and baroreceptors are involved in maintaining a constant blood pressure

Aimed at advanced biology students, this resource leads students through the design and use of a respirometer. The first few questions deal with causes of pressure changes inside a respirometer tube and predicting the direction in which fluid within a manometer tube would flow. The worksheet then moves on to cover two different investigations - measuring the amount of oxygen consumed over time and measuring the amount of carbon dioxide produced over time. Tables for the recording of data and calculations (e.g. converting distance measurments to volumes) are provided along with questions that check understanding. The data gathered from both oxygen consumption and carbon dioxide can be plotted as graphs to calculate rate of respiration or used to calculate RQ values, indicating which respiratory substrate is being used by the organisms under test (blowfly larvae are suggested). The second worksheet in this resource deals specifically with a thermo-barometrically balanced respirometer and calculation/interpretation of RQ values. Key words: respirometer, manometer, blowfly larvae, maggots, rate, RQ value, volume, distance, temperature, control, potassium hydroxide, thermo-barometrically balanced