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Bioscience Rocks

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Bioscience Rocks is a shop that specialises in resources for A-Level Biology and Applied Science students. The resources include a range of activities, starters, worksheets and powerpoints, all of which have been used successfully with students of a wide range of abilities. The author is a National Expert Teacher of Science (awarded by National Science Learning Centre) and also a National Space Academy Lead Educator with a long track record of producing high quality educational resources.

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Bioscience Rocks is a shop that specialises in resources for A-Level Biology and Applied Science students. The resources include a range of activities, starters, worksheets and powerpoints, all of which have been used successfully with students of a wide range of abilities. The author is a National Expert Teacher of Science (awarded by National Science Learning Centre) and also a National Space Academy Lead Educator with a long track record of producing high quality educational resources.
Mitosis and Meiosis comparison  table
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Mitosis and Meiosis comparison table

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A resource aimed at advanced level biology students, this worksheet provides a comparison table for mitosis, meiosis I and meiosis II. Students often confuse the events of these processes, particularly the movement of chromosomes and so it is a useful exercise to clarify which events happen where. Keywords: mitosis, meiosis, chromosomes, chromatid, diploid, haploid, centriole, centromere
Meiosis revision and non-disjunction
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Meiosis revision and non-disjunction

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A worksheet aimed at advanced level biology students, this resource recaps understanding of the movement and appearance of chromosomes during meiosis. The worksheet also asks students to consider the underlying reasons for an unusual karyotype (Klinefelter's syndrome) and how this relates to the process of meiotic cell division. Keywords: Klinefelter's syndrome, meiosis, division, chromosomes, cells, non-disjunction, mutation, disorder, genes, loci, haploid, diploid
Meiosis starter exercise
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Meiosis starter exercise

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A worksheet aimed at advanced biology students, this worksheet is ideal as a starter task (or alternatively as a homework preparation/background reading exercise) that covers the reasons why meiosis takes place and the nature of gametes produced from meiosis. This is a useful exercise to conduct with students to establish the 'big picture' prior to study of individual stages of meiotic cell division. Keywords: meiosis, chromosomes, interphase, prophase, metaphase, anaphase, telophase, haploid, diploid, reduction division, independent assortment, variation, genetic, evolution
Meiosis - understanding the appearance of chromosomes, gene loci and reduction division
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Meiosis - understanding the appearance of chromosomes, gene loci and reduction division

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A worksheet aimed at advanced biology students, this resource aims to clarify details that students often struggle with in their understanding of meiosis. The worksheet requires students to draw a pair of chromosomes in a cell that will undergo meiotic cell division; students are asked to label the pair of chromosomes with genes and show the appearance of these chromosomes after DNA replication has occured, after meiosis I and after meiosis II. The worksheet also includes questions that students are required to answer in order to test their understanding of meiosis. This resource is a valuable exercise to conduct with students in order to identify and address misconceptions/misunderstandings that can often occur in this topic. Keywords: meiosis, chromosomes, interphase, prophase, metaphase, anaphase, telophase, DNA, replication, diploid, haploid, gene, loci, heterozygous, homozygous
Key words mitosis
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Key words mitosis

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A worksheet aimed at advanced level biology students, this resource provides a list of key statements and key words related to the topic of mitosis. The worksheet can be used as a revision activity whereby students draw out cell diagrams depicting each stage of mitosis and then use the key words and statements to annotate their diagrams appropriately. Key words: key words, key statements, mitosis, centrioles, prophase, metaphase, anaphase, telophase, cytokinesis, interphase, chromosomes, nucleus, spindle fibres
Homologous chromosomes
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Homologous chromosomes

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A worksheet aimed at advanced level biology students, this resource focuses on the nature of chromosomes, the difference between haploid and diploid cells, the concept of a gene locus and the appearance of chromosomes at different stages of cell division - students are often confused by the single stranded versus double stranded chromosomes and so this is a useful exercise to undertake at the start of any topic involving mitosis or meiosis. Key words: chromosomes, meiosis, mitosis, genetics, locus, allele, diploid, haploid
Sickle cell disease
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Sickle cell disease

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A worksheet aimed at advanced level biology students, this resource uses the context of sickle cell disease to provide synoptic style questions on the nature of haemoglobin, the phenomenon of incomplete dominance, the link between sickle cell disease and malaria and finally, the phenomenon of heterozygote advantage. Key words: sickle cell, heterozygote advantage, malaria, incomplete dominance
Pink sheepdogs - monohybrid cross
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Pink sheepdogs - monohybrid cross

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A worksheet that recaps the basics of monohybrid cross diagrams using a (hypothetical) pink sheepdog as an example! The worksheet provides a template for students to organise and lay out their work clearly and finsihes with a challenge question requiring students to explain why predicted ratios do not necessarily match actual ratios. Key words: monohybrid, test, back, cross, predicted, inheritance, dominant, recessive
Monohybrid cross
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Monohybrid cross

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A resource aimed at 14-18 year old biology students, this worksheet provides an exercise on the inheritance of coat colour in dogs. The worksheet provides a template for students to organise their cross diagrams carefully and also provides a challenge question at the end, requiring students to explain how they could test for homozygosity (the classic 'test cross' or 'back cross'). Key words: Monohybrid, inheritance, genetics, test cross, back cross
Monohybrid Inheritance - the full story
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Monohybrid Inheritance - the full story

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A resource aimed at advanced biology students, this worksheet provides a comprehensive summary of revision notes on the topic of monohybrid inheritance and Gregor Mendel's classic experiments. The worksheet requires missing words to be entered in the appropriate spaces. Once complete, students have a set of revision notes for their file. The second worksheet provides all the answers, making it possible to set this as a homework exercise that students can then self mark back in class. Key words: Mendel, monohybrid, cross, genetics, inheritance
HIV - the evolution of a virus
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HIV - the evolution of a virus

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A worksheet aimed at advanced biology students, this resource focuses on how the HIV virus has evolved resistance to drug treatments over the last few decades and how some individuals have evolved resistance to the virus. The resource contains two articles (from BBC News and Medical News Today) as stimulus material followed by questions that require students to link their knowledge to these real-life applied examples. This resource is ideal stretch and challenge material for more able students once they have completed a topic on evolution. Key words: HIV, resistance, evolution, disease, virus, AIDS, drugs, medicine
Haemophilia - interpreting the results of a Royal Family pedigree
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Haemophilia - interpreting the results of a Royal Family pedigree

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A resource aimed at advanced biology students, this worksheet requires students to interpret the British Royal Family pedigree chart and explain the inheritance of haemophilia from Queen Victoria (thought to be where the mutation first arose) onwards. Keywords: pedigree, chart, genetics, haemophilia, gene, allele, mutation, probablility
Gregor Mendel and the chi-squared test
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Gregor Mendel and the chi-squared test

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A resource aimed at advanced biology students, this worksheet provides a template for students to work through Gregor Mendel's classic pea breeding experiments showing the results of the genetic cross. The template includes prompts for students to set out their working clearly, showing parental phenotype, genotype, gametes and offspring genotype and phenotype. The second page of the worksheet provides a template for students to work through an analysis of Gregor Mendel's actual results using the chi-squared test. A data table is included in order to determine whether results are significant or not; note that this is one of the rare cases where non-significance (between observed and expected data) actually lends weight to a theory - Mendel's results are not significantly different to those proposed by his theory. Key words: Mendel, genetics, pea, breeding, cross, diagrams, monohybrid, chi-squared, statistics, observed, expected, data
Introduction to genetics - bridging between meiosis and genetics
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Introduction to genetics - bridging between meiosis and genetics

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A resource aimed at advanced biology students, these two worksheets bridge the gap between the topics of meiosis and genetics. The first worksheet requires students to recap their knowledge and understanding of meiosis by drawing out the appearance of chromosomes (labelled with genes and alleles) at different stages of cell division. The second worksheet requires students to match definitions to key words (e.g. gene, allelle, homozygous, heterozygous, etc) and identify which characteristics are caused by genetic/environmental factors. Key words: genetics, meiosis, allele, gene, homozygous, heterozygous, gamete, dominant, recessive
Gene Technology Quiz
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Gene Technology Quiz

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A worksheet aimed at advanced level biology students, this resource provides a twenty question quiz on key processes involved in gene technology. The resource is ideal to use as a starter or plenary exercise once this topic has been taught, as a way of reinforcing key vocabulary and terms.
Directional selection in mallards
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Directional selection in mallards

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A worksheet aimed at advanced level biology students, this resource uses mallards as an example of directional selection. Students are required to predict the effect of climate changes to the amount of subcutaneous fat in a population of mallards over time. The worksheet requires students to predict the effect on a normal distribution curve and then finally explain the process of directional selection using the key phrases provided. Key words: directional, selection, mallard, normal distribution, reproductive success, differential, frequency, alleles, variation
Dihybrid cross questions with modified ratios
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Dihybrid cross questions with modified ratios

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A resource aimed at advanced biology students, this worksheet provides some more unusual examples of dihybrid cross genetics including malvidin production in primrose, kernel colour in wheat and fruit colour in squash; all students will be aware of the classic 9:3:3:1 ratio, but they can often struggle when other factors such as codominance are included in the question. This resource is ideal stretch and challenge material for more able students once they have mastered the basics of the dihybrid cross. It is also ideal preparation for the more challenging questions on this topic favoured by most exam boards. Keywords: dihybrid, ratio, cross, genetics
Continuous versus discontinuous variation
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Continuous versus discontinuous variation

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A resource aimed at 14-18 year old biology students, this worksheet is useful as a starter or plenary exercise comparing continuous and discontinuous variation. The worksheet requires students to identify which traits fall into which category and considers the classic normal distribution curve shown by continuously variable characteristics. For more able students, the worksheet includes a section on using standard deviation to predict the percentage of the population that would occupy certain ranges. Key words: continuous, variation, discontinuous, genetics, monogenic, polygenic
Codominance questions
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Codominance questions

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A worksheet aimed at advanced biology students, this resource consists of eight questions that focus on both multiple alleles and codominance. The examples chosen include fur colour in cats, hair colour in cattle and the appearance of the (fictional) American Bigfoot! A good resource to use as either a starter or plenary exercise to test understanding of either codominance or multiple alleles and phenotypic ratios. Key words: genetics, phenotype, codominance, multiple alleles, monohybrid