This fully-resourced lesson looks at the use of electrocardiograms to aid the diagnosis of abnormal heart rhythms. The engaging PowerPoint and accompanying resources have been designed to cover point 7.12 (iii) of the Edexcel International A-level Biology specification but also can be used as a revision lesson as the students are challenged on their prior knowledge of the cardiac cycle and heart structure as covered in topic 1. The lesson has been written to take place in an imaginary cardiology ward where the students are initially challenged on their knowledge of the symptoms and risk factors of CVD before looking at testing through the use of ECGs and diagnosis. The main focus of the lesson is the ECG and a quiz competition is used to introduce the reference points of P, QRS and T before time is taken to explain their representation with reference to the cardiac cycle. Moving forwards, a SPOT the DIFFERENCE task is used to challenge the students to recognise differences between sinus rhythm and some abnormal rhythms including tachycardia and atrial fibrillation. Bradycardia is used as a symptom of sinus node disfunction and the students are encouraged to discuss this symptom along with some others to try to diagnose this health problem. This lesson has been designed to tie in with the lesson that covers the previous specification point on the normal electrical activity of the heart and the myogenic nature of cardiac muscle

This fully-resourced lesson describes the behaviour of chromosomes during the mitotic cell cycle and explains the importance of this type of nuclear division. The PowerPoint and accompanying resources have been designed to cover points 5.1 (b) & 5.2 (a) of the CIE A-level Biology specification and make direct links to a previous lesson which covered the outline of cell cycle Depending upon the exam board taken at iGCSE, the knowledge and understanding of mitosis will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson so that existing errors are addressed and key points are emphasised throughout. Their understanding of interphase is challenged at the start of the lesson to ensure that they realise that it is identical pairs of sister chromatids that enter the M phase. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. There is a focus on the centrioles and the spindle fibres that they produce which contract to drag one chromatid from each pair in opposite directions to the poles of the cell. The remainder of the lesson is a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final quiz round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture.

This lesson describes how the critical evaluation of new data by the scientific community leads to new taxonomic groupings, like the three domains of life. The detailed PowerPoint and accompanying resources have been designed to cover point 4.6 (ii) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification and focuses on the introduction of the three-domain system following Carl Woese’s detailed study of the ribosomal RNA gene. The lesson begins with an introduction of Woese and goes on to describe how he is most famous for his definition of the Archaea as a new domain of life. Students were introduced to domains and the other classification taxa in a previous lesson, so their recall of this knowledge is continually tested and built upon as details are added. Students will discover the key differences between Archaea and Bacteria that led to the splitting of the prokaryotae kingdom and the addition of this higher classification rank. Moving forwards, the rest of the lesson describes how molecular phylogeny uses other molecules and that these are compared between species for classification purposes. One of these is a protein called cytochrome which is involved in respiration and can be compared in terms of primary structure to determine relationships. At this point in the lesson, the students are also tested on their knowledge of the nature of the genetic code (as covered in topic 2) and have to explain how mutations to DNA can also be used for comparative purposes.

This lesson explains that autosomal linkage results from the presence of alleles on the same chromosome and uses biological examples to demonstrate this concept. The PowerPoint and accompanying worksheets have been designed to cover point 8.2 (iv) of the Edexcel A-level Biology B specification and supports students in the formation of their descriptions of how these results of these crosses can be explained by the events of meiosis (crossing over) This is a difficult topic which can be poorly understood by students so extra time was taken during the planning to split the concept into small chunks. There is a clear focus on using the number of parent phenotypes and recombinants in the offspring as a way to determine linkage and suggest how the loci of the two genes compare. Important links to other topics such as crossing over in meiosis are made to enable students to understand how the random formation of the point of contact (chiasma) determines whether new phenotypes will be seen in the offspring or not. Linkage is an important cause of variation and the difference between observed and expected results and this is emphasised on a number of occasions and a link to the chi squared test which is covered in an upcoming lesson is also made. The main task of the lesson act as understanding check where students are challenged to analyse the results of genetic crosses involving the inheritance of the ABO blood group gene and the nail-patella syndrome gene n humans and also the inheritance of body colour and wing length in Drosophila.

This fully-resourced lesson describes the blood clotting process and includes the release of thromboplastin and the subsequent conversions to thrombin and fibrin. The engaging PowerPoint and accompanying worksheets have been primarily designed to cover the content detailed in point 1.6 of the Pearson Edexcel A-level Biology A specification but time has been taken to look at haemophilia as a sex-linked disease so that students are prepared for sex-linkage when covered in topic 3. The lesson begins with the introduction of clotting factors as integral parts of the blood clotting process and explains that factor III, thromboplastin, needs to recalled as well as the events that immediately precede and follows its release. Students will learn how damage to the lining and the exposure of collagen triggers the release of this factor and how a cascade of events then results. Quick quiz rounds and tasks are used to introduce the names of the other substances involved which are prothrombin, thrombin, fibrinogen and fibrin. In a link to the upcoming topic of proteins, students will understand how the insolubility of fibrin enables this mesh of fibres to trap platelets and red blood cells and to form the permanent clot. In the previous lessons, students described the events in atherosclerosis and a link is made to the role of blood clotting in CVD. The final part of the lesson introduces haemophilia as a sex-linked disease and students are challenged to apply their knowledge to an unfamiliar situation as they have to write genotypes and determine phenotypes before explaining why men are more likely to suffer from this disease than women.

This detailed lesson describes the key structural features of a prokaryotic cell and compares these against the structures of an eukaryotic cell. The engaging PowerPoint and accompanying resources have been designed to cover specification points 1.2 (d) & (e) as detailed in the CIE International A-level Biology specification and describes how the size and cell structures differ as well as the additional features that are found in some prokaryotic cells and briefly introduces binary fission. A clear understanding of terminology is important for A-level Biology so this lesson begins with a challenge, where the students have to recognise a prefix that they believe translates as before or in front of . This leads into the discovery of the meaning of prokaryote as before nucleus and this acts to remind students that these types of cell lack this cell structure. Links to the previous lessons on the eukaryotic cells are made throughout the lesson and at this particular point, the students are asked to work out why the DNA would be described as naked and to state where it will be found in the cell. Moving forwards, the students will discover that these cells also lack membrane bound organelles and a quick quiz competition challenges them to identify the specific structure that is absent from just a single word. In addition to the naked DNA, students will learn that there are also ribosomes in the cytoplasm and will discover that these are smaller than those found in the cytoplasm of an eukaryotic cell (but the same size as those in chloroplasts and mitochondria). The remainder of the lesson focuses on the composition of the cell wall, the additional features of prokaryotic cells such as plasmids and there is also the introduction of binary fission as the mechanism by which these organisms reproduce

This fully-resourced lesson describes how DNA is replicated semi-conservatively, including the roles of DNA helicase, polymerase and ligase. The detailed PowerPoint and accompanying resources have been designed to cover point 1.4 (ii) of the Edexcel A-level Biology B specification The main focus of this lesson is the roles of DNA helicase in the breaking of the hydrogen bonds between nucleotide bases, DNA polymerase in forming the growing nucleotide strands and DNA ligase in the joining of the nucleic acid fragments. Time is taken to explain key details, such as the assembly of strands in the 5’-to-3’ direction, so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure and hydrolysis reactions through a range of exam questions and answers are displayed so that any misconceptions are quickly addressed. The main task of the lesson asks the students to use the information provided in the lesson to order the sequence of events in DNA replication before discussing how the presence of a conserved strand and a newly built strand in each new DNA molecule shows that it is semi-conservative.

This fully-resourced lesson describes how allopatric or sympatric speciation may result from geographical, ecological or behavioural separation. The engaging PowerPoint and accompanying resources have been designed to cover point 17.3 [c] of the ICE A-level Biology specification and uses actual biological examples to increase the relevance and likelihood of understanding The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.

This lesson describes the role of the cardiovascular control centre in the medulla oblongata in the control of heart rate. The engaging and detailed PowerPoint and accompanying resources have been designed to cover the first part of point 7.13 (ii) of the Edexcel International A-level Biology specification and explains how this regulation enables the rapid delivery of oxygen and the removal of carbon dioxide. This lesson begins with a prior knowledge check where students have to identify and correct any errors in a passage about the conduction system of the heart. This allows the SAN to be recalled as this structure play an important role as the effector in this control system. Moving forwards, the three key parts of a control system are recalled as the next part of the lesson will specifically look at the range of sensory receptors, the coordination centre and the effector. Students are introduced to chemoreceptors and baroreceptors and time is taken to ensure that the understanding of the stimuli detected by these receptors is complete and that they recognise the result is the conduction of an impulse along a neurone to the brain. A quick quiz is used to introduce the medulla oblongata as the location of the cardiovascular centre. The communication between this centre and the SAN through the autonomic nervous system can be poorly understood so detailed explanations are provided and the sympathetic and parasympathetic divisions compared. The final task challenges the students to demonstrate and apply their understanding by writing a detailed description of the control and this task has been differentiated three ways to allow differing abilities to access the work

This fully-resourced lesson describes how selection pressures act on a gene pool and cause stabilising, directional and disruptive selection. The PowerPoint and accompanying resources have been designed to cover point 8.3 (i) of the Edexcel A-level Biology B specification which states that students should be able to identify each type of selection by its effect on different phenotypes. The lesson begins with an introduction to the mark, release, recapture method to calculate numbers of rabbits with different coloured fur in a particular habitat. This shows changes in numbers of the organisms and sketch graphs are then constructed to show these changes in the population size. A quick quiz competition is used to engage the students whilst introducing the names of the three main types of selection before a class discussion point encourages the students to recognise which specific type of selection is represented by the rabbits. Key terminology including intermediate and extreme phenotypes and selection pressure are used to emphasise their importance during explanations. A change in the environment of the habitat and a change in the numbers of the rabbits introduces directional selection before students will be given time to discuss and to predict the shape of the sketch graph for disruptive selection. Students are challenged to apply their knowledge in the final task of the lesson by choosing the correct type of selection when presented with details of a population and answer related questions.

This is an engaging lesson that looks at the structures and actions of the two parts of the autonomic nervous system (ANS) and shows students where this particular system fits into the whole organisation of the nervous system. The lesson begins by introducing the students to the idea that motor neurones are not simply somatic motor neurones but will actually be classified as autonomic motor neurones if they innervate the involuntary muscles. A range of tasks, progress checks and quick competitions are used during the lesson to engage the students in this topic and show them how it relates to other topics such as motor neurones and neurotransmitters. Key terminology is used throughout, such as ganglions, so that students can recognise and access the marks if an exam question on this topic arises. This lesson has been written for A-level students

This lesson focuses on the structure of RNA and specifically the similarities and differences between this nucleic acid and DNA so that students are prepared for the upcoming lessons on transcription and translation. The engaging and detailed PowerPoint and accompanying resource have been designed to cover part 1 of point 2.1.3 (g) of the OCR A-level Biology A specification which states that students should be able to describe the structure of molecules of messenger RNA, transfer RNA and ribosomal RNA. Students were introduced to nucleotides and the detailed structure of DNA in previous lessons, so this lesson is written to tie in with those and continuously challenge prior knowledge as well as understanding of the current topic. The lesson begins by reminding students that RNA is a member of the family of nucleic acids and therefore has a number of structural features that are commonly shared with DNA. A quiz round called “A FAMILY AFFAIR” is used to challenge their knowledge of DNA to recognise those features that are also found on RNA such as the chain of linked nucleotides, pentose sugars, nitrogenous bases and phosphodiester bonds. The next task pushes them to consider features that have not been mentioned and therefore are differences as they answer a structured exam-style question on how RNA differs from DNA. Students will learn that RNA is shorter than DNA and this leads into the final part of the lesson where mRNA and tRNA are introduced and again they are challenged to use the new information explain the difference in size. Brief details of transcription and then translation are provided so that students are prepared for the upcoming lessons on protein synthesis.

This is an engaging and informative lesson that looks at the properties of water and challenges students to be able to explain how these properties are related to the numerous functions of this biological molecule. This lesson focuses on the link between properties and functions which is the area where students commonly struggle. A range of tasks and activities, including a quick competition are used to introduce the different properties and the key terms and then time is taken to look at how this property enables water to be used for a range of functions. Students will learn that water has both a high specific heat capacity and a high latent heat of vaporisation and be able to explain why this is important. Water is a crucial solvent which enables it to perform many roles in living organisms and these are explored. Progress checks are written into the lesson at regular intervals so that students can constantly assess their understanding and build on any knowledge that was there from GCSE.

This revision resource contains an engaging and informative PowerPoint (49 slides) and a differentiated worksheet that will enable the students to assess their understanding of the topic B2 (Cells) content of the CIE IGCSE Combined Science specification for examination in June and November 2020 and 2021. The following topics have been given particular attention in this lesson: The structure and function of red blood cells Diffusion as the movement of molecules from a high concentration to a low concentration The structure of root hair cells to allow absorption of minerals and water from the soil Osmosis investigations The effect on plant cells of immersion in solutions of different water potentials The function of the organelles found in animal and plant cells The structure and function of specialised cells This resource is ideal for revision purposes during or at the end of the topic and in the lead up to mocks or the actual IGCSE exams

This lesson has been designed to cover the content as detailed in points 2.15, 2.16 and 2.17 (The eye as a sensory receptor and the correction of eye defects) of the Edexcel GCSE Biology specification. Consisting of a detailed and engaging PowerPoint (54 slides) and accompanying worksheets, the range of activities will motivate the students whilst ensuring that the content is covered in detail. Students will learn how the structures of the eye enable it to function as a sensory receptor, with a particular focus on the role of the cornea, lens, iris and the rod and cone cells in the retina. In addition, students will understand how eye defects such as short-sightedness and cataracts can cause problems for vision and can be corrected. Progress checks are included throughout the lesson so that students can assess their understanding of the content and any misconceptions can be addressed whilst quiz competitions are used to introduce new terms in a fun and memorable way. This lesson has been written for GCSE-aged students who are studying the Edexcel GCSE Biology specification but can be used with younger students who have a real interest in this sensory receptor as well as older students who need to know the key details for their A level course.

This is a fully-resourced lesson consisting of an engaging PowerPoint and differentiated worksheets which have been designed to cover the content of points 7.15 & 7.16 as detailed on the Edexcel GCSE Biology & Combined Science specifications. This point states that students should be able to describe the cause of diabetes type I and II and describe how they are both controlled. There are links made throughout the lesson between this topic and the control of blood glucose concentration from specification point 7,13 and 7.14 The lesson has been designed to take the format of a diabetic clinic where the students perform the duties of the attending doctor. They will move through the different expectations of the role which includes identifying symptoms, diagnosis of type I or II and communication with the patients to reveal the findings. The wide range of activities will enable the students to learn how to spot that someone is suffering from diabetes and the similarities and differences between the different types so they can determine which one is being presented. The summary tasks challenge the students to construct a letter to a patient who is suffering from type II and to identify the correct type from another doctor’s letter. Understanding and previous knowledge checks are interspersed with quiz competitions, like the one shown in the cover image, which make the learning fun and memorable and enable the students to assess their progress. This lesson has been designed for students studying the Edexcel GCSE Biology or Combined Science course but is suitable for both younger and older students who are focusing on this disease

This detailed and fully-resourced lesson describes the relationship between the structure and function of glycogen and starch. The engaging PowerPoint and accompanying resources have been designed to cover the fourth part of points 1.12 & 1.13 of the Pearson Edexcel A-level Biology A specification and clear links are also made to the previous lessons in this topic where the monosaccharides and disaccharides were introduced. The lesson begins with the CARBOHYDRATE WALL where students have to use their prior knowledge to collect the 9 carbohydrates on show into 3 groups. This results in glycogen, starch and cellulose being grouped together as polysaccharides and the structure and roles of the first two are covered over the course of the lesson. Students will learn how key structural features like the 1 - 4 and 1 - 6 glycosidic bonds and the hydrogen bonds dictate whether the polysaccharide chain is branched or unbranched and also allows for spiralling. Following the description of the structure of glycogen, students are challenged to design an exam question in the form of a comparison table so that it can be completed as the lesson progresses and they learn more about starch. This includes a split in the starch section of the table so that the differing structures and properties of amylose and amylopectin can be considered. The importance of the compact structure for storage is discussed as well as the branched chains of amylopectin acting as quick source of energy when it is needed. The lesson concludes with a question and answer section that guides the students when answering a question about the importance of the lower solubility of the polysaccharides when compared to the monosaccharides.

This engaging lesson looks at the myogenic nature of cardiac muscle and explores the roles of the SAN, AVN, Bundle of His and Purkyne fibres in the normal electrical activity of the heart. The PowerPoint and accompanying resources have been designed to cover the points 7.8 (i & ii) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification. The lesson begins with the introduction of the SAN as the natural pacemaker and then time is given to study each step of the conduction of the impulse as it spreads away from the myogenic tissue in a wave of excitation. The lesson has been written to make clear links to the cardiac cycle and the structure of the heart and students are challenged on their knowledge of this system from topic 1. Moving forwards, students are encouraged to consider why a delay would occur at the AVN and then they will learn that the impulse is conducted along the Bundle of His to the apex so that the contraction of the ventricles can happen from the bottom upwards. The structure of the cardiac muscle cells is discussed and the final task of the lesson challenges the students to describe the conducting tissue, with an emphasis on the use of key terminology Due to the detailed nature of this lesson, it is estimated that it will take about 2 hours of A-level teaching time to cover the two specification points

An informative lesson presentation (30 slides) that ensures that students know the meaning of the independent, dependent and control variables in an investigation and are able to identify them. Students are challenged to use their definitions to spot the independent and dependent variable from an investigation title. Moving forwards, they are shown how they can use tables and graphs to identify them. The rest of the lesson focuses on the control variables and how these have to be controlled to produce valid results This lesson is suitable for students of all ages studying Science as it is such a key skill

This fully-resourced lesson has been designed to cover the content in point 3.17 (Inheritance of ABO blood groups) as detailed in the Edexcel GCSE Biology specification. As specified in this point, students will learn how this inheritance demonstrates both codominance and multiple alleles. A potentially difficult topic, time has been taken to include guidance sections where students are walked through the interpretation of the different genotypes to find out the phenotypes as well as constructing genetic diagrams and calculating blood groups from pedigree trees. There is a real focus on genetic terminology such as allele, locus, genotype and phenotype so that the understanding is deep and students can use this if they choose to further their studies at A-level. This lesson has been designed for GCSE-aged students studying the Edexcel GCSE Biology course but is also suitable for older students who are learning about codominance and multiple alleles at A-level