This fully-resourced lesson describes the non-specific responses of the body to infection and includes details of phagocytosis, inflammation and interferon release. The engaging and detailed PowerPoint and accompanying resources have been primarily designed to cover the content of point 6.7 of the Pearson Edexcel A-level Biology A specification but topics including antigen-presentation are also introduced to prepare students for upcoming lessons on the immune response (6.8 & 6.9). At the start of the lesson, the students are challenged to recall that cytosis is a suffix associated with transport mechanisms and this introduces phagocytosis as a form of endocytosis which takes in pathogens and foreign particles. This emphasis on key terminology runs throughout the course of the lesson and students are encouraged to consider how the start or end of a word can be used to determine meaning. The process of phagocytosis is then split into 5 key steps and time is taken to discuss the role of opsonins as well as the fusion of lysosomes and the release of lysozymes. A series of application questions are used to challenge the students on their ability to make links to related topics including an understanding of how the hydrolysis of the peptidoglycan wall of a bacteria results in lysis. Students will be able to distinguish between neutrophils and monocytes from a diagram and at this point, the role of macrophages and dendritic cells as antigen-presenting cells is described so that it can be used in the next lesson. The importance of cell signalling for an effective immune response is discussed and the rest of the lesson focuses on the release of two chemicals - interferons and histamine. During the interferon section, references are made to a previous lesson on HIV structure and action so students can understand how the release of these signalling proteins helps neighbouring cells to heighten their anti-viral defences. A step by step guide is used to describe the release of histamine in the inflammatory response and the final task challenges students to use this support to form a detailed answer regarding the steps in inflammation.

This lesson describes the effect that treaties such as CITES have had on global diversity. The PowerPoint and accompanying worksheets have been primarily designed to cover point 10.4 (ii) of the Edexcel A-level Biology B specification but has been planned to constantly challenge them on their knowledge of topic 3.3 (biodiversity) as a local conservation agreement is also considered Many hours of research have gone into the planning of this lesson to ensure that a range of interesting biological examples are included, with the aim of fully engaging the students in the material to increase its relevance. The students will learn that the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) was first agreed in 1973 and that 35000 species are currently found in appendix I, II or III. Time is taken to go through the meaning of each appendix and then the following animal and plant species are used to explain the finer details of the agreement: Tree pangolin, eastern black rhino for CITES appendix I Darwin’s orchid for CITES appendix II Four-horned antelope for CITES appendix III Exam-style questions are used to check on their understanding of the current topic as well as to challenge their knowledge of previously-covered topics such as the functions of keratin, when considering the structure of the rhino horn. Each of these questions has its own markscheme which is embedded in the PowerPoint and this allows the students to constantly assess their progress. The final part of the lesson considers the Countryside Stewardship Scheme as a local conservation agreements and discusses the reasons behind some of the key points. Students are told that farmers, woodland owners, foresters and land managers can apply for funding for a range of options including hedgerow management, low input grassland, buffer strips, management plans and soil protection options. The importance of the hedgerows for multiple species is discussed, and again a real-life example is used with bats to increase the likelihood of retention. The last task challenges them to use their overall knowledge of biodiversity to explain why buffer strips consisting of multiple types of vegetation are used and to explain why these could help when a farmer is using continuous monoculture.

An engaging lesson presentation and associated worksheet that looks at the use of antibiotics to treat bacterial infections and the raises the issue of the potential over-use of these substances. The lesson begins by getting the students to recognise the difference between three key terms that begin with anti (antibiotics, antivirals, antiseptics). Students will be introduced to the idea that antibiotics are specific to a small range of bacteria and therefore the correct one has to be selected before being prescribed. Moving forwards, students will meet the idea of the zone of inhibition and will understand how the size of this zone can be used as an indicator to the effectiveness of the treatment. Students are shown how to calculate the size of the zone and then are tested on their ability to apply this mathemetical knowledge. Finally, time is taken to look at the links to the topic of natural selection to explain how some bacteria are resistant to certain antibiotics. There are regular progress checks throughout the lesson so that students can assess their understanding. This lesson has been designed for GCSE students but could be used as an introduction with A-level Biology students who are about to begin the topic of immunity.

An engaging lesson presentation (39 slides) with associated differentiated worksheets that looks at they key differences between pure and impure substances and briefly explores how a mixture like an alloy can still be very useful. The lesson begins by challenging the students to recognise 4 diagrams of pure substances from a selection of 5. This will lead students to the definition of pure (in Science) which is likely to be different to what they have encountered in everyday language. The next task gets the students to draw a graph showing the melting and boiling points of pure water. This will enable them to compare the melting point against that of an impure substance and therefore recognise that this difference can be used as point to decide on purity. An example of gritting is used to explain how this change in melting point can be utilised and then the students are challenged to apply this new-found knowledge to the situation of adding salt to boiling water when making pasta. The remainder of the lesson focuses on some famous mixtures. Beginning with air, students will be able to visualise how this mixture is made of a number of gases, each with different boiling points which allows them to be separated by fractional distillation. Alloys are briefly explored so that students know why these mixtures are used for certain functions over pure metals and the summary passage for this task has been differentiated two ways so that all can access the work. Progress checks have been written into the lesson at regular intervals so that students can check their understanding and a range of quick quiz competitions are used to maintain engagement whilst introducing new terms in a fun manner. If you want to look into alloys in greater detail, then this lesson could be combined with the one named “alloys” which is also uploaded.

This fully-resourced lesson describes the key steps in the process of DNA replication, including the role of DNA polymerase. Both the detailed PowerPoint and accompanying resources have been designed to cover point 2.11 (i) of the Pearson Edexcel A-level Biology A specification and this lesson also explains why this replication is known as semi-conservative in order to prepare the students for the following lesson on Meselson and Stahl’s experiment. The main focus of this lesson is the role of DNA polymerase in the formation of the growing nucleotide strands but the students will also learn that the hydrogen bonds between nucleotide bases are broken by DNA helicase and that DNA ligase joins the nucleic acid fragments. Time is taken to explain key details, such as the assembly of strands in the 5’-to-3’ direction, so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure and hydrolysis reactions through a range of exam questions and answers are displayed so that any misconceptions are quickly addressed. The main task of the lesson asks the students to use the information provided in the lesson to order the sequence of events in DNA replication before discussing how the presence of a conserved strand and a newly built strand in each new DNA molecule shows that it is semi-conservative.

A highly engaging lesson presentation (74 slides) and accompanying worksheets that uses exam questions (with explained answers), quick tasks and quiz competitions to allow students to assess their understanding of the topic of Biological molecules (Topic 3.1). Students will have fun whilst recognising those areas of the specification which need further attention.

An engaging lesson presentation (48 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit P4 (Atomic structure) of the AQA GCSE Combined Science specification (specification point P6.4). The topics that are tested within the lesson include: The structure of an atom Isotopes Radioactive decay and nuclear radiation Nuclear equations Half-lives Students will be engaged through the numerous activities including quiz rounds like “It’s as easy as ABG” and “ALPHA or BETA” whilst crucially being able to recognise those areas which need further attention

A fun and engaging lesson presentation (33 slides) and associated worksheet that uses exam questions, with fully explained answers, quick tasks and competitions to allow students to assess their understanding of Module 3.1.2 (Transport in Animals). The students will enjoy the lesson whilst being able to recognise which areas of the specification need further attention. Competitions included in the lesson are “SPOT THE ERROR”, “Where’s Lenny” and “Crack the code”

An engaging lesson presentation (61 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B5 (Genes, inheritance and selection) of the OCR Gateway A GCSE Biology specification The topics that are tested within the lesson include: Sexual and asexual reproduction Meiosis Dominant and recessive alleles Genetic crosses The history of genetics Natural selection Classification systems Students will be engaged through the numerous activities including quiz rounds like “Number CRAZY" and “Which Scientist is hidden?” whilst crucially being able to recognise those areas which need further attention

This fully-resourced REVISION LESSON has been designed to provide the students with numerous opportunities to assess their understanding of the content of module 5.2.2 (Respiration) of the OCR A-level Biology A specification. The importance of this metabolic reaction is obvious and this is reflected in the volume of questions in the terminal exams which require an in depth knowledge of the stages of both aerobic and anaerobic respiration. The lesson contains a wide range of activities that cover the following points of the specification: Glycolysis as a stage of aerobic and anaerobic respiration The use and production of ATP through respiration Anaerobic respiration in mammalian muscle tissue The stages of aerobic respiration that occur in the mitochondrial matrix Oxidative phosphorylation The use of respirometers Calculating the respiratory quotient value for different respiratory substrates Revision lessons which cover the other sub-modules of module 5 are uploaded and tie in well with this content

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick differentiated tasks and quiz competitions to help the students to assess their understanding of the topics found within Topic C2 (Inorganic chemistry) of the Edexcel iGCSE Chemistry specification which has its’ first assessment in 2019. The topics that are tested within the lesson include: Group 1 (alkali metals) Group 7 (halogens) Gases in the atmosphere Reactivity series Extraction and uses of metals Acids, alkalis and titrations Chemical tests Students will be engaged through the numerous quiz rounds whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual assessment. The detail of this lesson means that it could be used over a number of lessons at school so that each topic is covered in sufficient depth.

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Topic P3 (Particle model of matter) of the AQA Trilogy GCSE Combined Science specification. The sub-topics and specification points that are tested within the lesson include: Density of materials Changes of state Temperature changes in a system and specific heat capacity Changes of heat and specific latent heat Students will be engaged through the numerous quiz rounds whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual GCSE terminal exams

This revision lesson has been designed to challenge the students on their use of a range of mathematical skills that could be assessed on the AQA GCSE Combined Science papers. The mathematical element of the AQA GCSE Combined Science course has increased significantly since the specification change and therefore success in those questions which involve the use of maths can prove to be the difference between one grade and another or possibly even more. The engaging PowerPoint and accompanying resources contain a wide range of activities that include exam-style questions with displayed mark schemes and explanations so that students can assess their progress. Other activities include differentiated tasks, class discussion points and quick quiz competitions such as “YOU DO THE MATH” and “FILL THE VOID”. The following mathematical skills (in a scientific context) are covered in this lesson: The use of Avogadro’s constant Rearranging the formula of an equation Calculating the amount in moles using mass and relative formula mass Calculating the relative formula mass for formulae with brackets Using the Periodic Table to calculate the number of sub-atomic particles in atoms Changes to electrons in ions Balancing chemical symbol equations Converting between units Calculating concentration in grams per dm cubed and volumes of solutions Calculating size using the magnification equation Using the mean to estimate the population of a sessile species Calculating percentages to prove the importance of biodiversity Calculating percentage change Calculating the acceleration from a velocity-time graph Recalling and applying the Physics equations Understanding prefixes that determine size Leaving answers to significant figures and using standard form Helpful hints and step-by-step guides are used throughout the lesson to support the students and some of the worksheets are differentiated two ways to provide extra assistance. Due to the detail of this lesson, it is estimated that it will take in excess of 3 hours of GCSE teaching time to cover the tasks and for this reason it can be used over a number of lessons as well as during different times of the year for revision.

This extensive revision lesson challenges students on their knowledge and understanding of the content of topics 5 - 8 of the AQA A-level specification. The PowerPoint and accompanying resources are detailed and engaging and contain a selection of tasks which challenge the following points: Directional, stabilising and disruptive selection Saltatory conduction and other factors affecting conductance speed The structure of a motor neurone Sensory receptors, depolarisation and initiation of an action potential Hardy-Weinberg principle Genetic terminology Codominance and sex-linkage Autosomal linkage Chi-squared test Phosphorylation The stages of aerobic respiration Explaining lower ATP yields in anaerobic respiration Skeletal muscle contraction Structure and function of slow and fast twitch muscle fibres The control of heart rate Electrophoresis and genetic fingerprinting The secondary messenger model The students are tested through a variety of tasks including exam questions, understanding checks, and quiz rounds to maintain engagement. Due to the mathematical content in all A-level exams, there is also a focus on these skills. The answers to all questions are embedded into the PowerPoint so students can use this resource outside of the classroom. The delivery of the whole lesson will likely need at least 2 or 3 hours of contact time so this resource could be used with students in the final weeks building up to their paper 2 exam, or alternatively with students before their mocks on these topics.

This fully-resourced revision lesson consists of an engaging PowerPoint and differentiated resources which together challenge the students on their knowledge of the Key concepts in Physics, which are detailed in topic 1 of the Pearson Edexcel GCSE Physics specification . The content in this topic is particularly important because it will be assessed in both paper 1 and paper 2 of the terminal exams. The lesson has been filled with a wide range of activities which test the following specification points: Recall and use the SI units for physical quantities Recall and use multiples and sub-multiples of units Be able to convert between different units Use significant figures and standard form# To fall in line with the heavy mathematical content of this specification, the main task of the lesson challenges the students to carry out a range of calculations where they have to convert between units and leave their answers in a specific form.