A fully-resourced lesson which explores the photosynthesis reaction, focusing on where it takes place and the reactants and products of this chemical reaction. This lesson includes an engaging and detailed lesson presentation (45 slides), a summary task and a crossword which is used throughout the lesson. Students will already have a fair knowledge of this topic from KS3 so this lesson has been written to take that knowledge and push it forward. Key details are added throughout the lesson such as how the reactants enter the plant by osmosis and diffusion and also how water travels from the roots to the leaves in the xylem vessel. An engaging competition runs during the lesson called “LIGHT up the crossword” and this enables the key terms of the topic to be stored in one place. There are two main written tasks during the lesson which challenge the students to summarise the reaction using all that they have learnt and also to state the different uses of glucose. The lesson has been linked to related topics with understanding checks written in at regular intervals so this knowledge can be assessed. This lesson has been written for GCSE students but could be used with higher ability KS3 students who want to learn more than they currently know

This fully-resourced lesson explores the inheritance of genetic characteristics that involve multiple alleles and codominant alleles. The engaging and detailed PowerPoint and differentiated worksheets have been designed to cover the part of point 6.1.2 (b[i]) which states that students should be able to demonstrate and apply their knowledge and understanding of genetic diagrams to show patterns of inheritance including multiple and codominant alleles. The main part of the lesson uses the inheritance of the ABO blood groups to demonstrate how the three alleles that are found at the locus on chromosome 9 and the codominance of the A and B alleles affects the phenotypes. Students are guided through the construction of the different genotypes and how to interpret the resulting phenotype. They are challenged to use a partially completed pedigree tree to determine the blood group for some of the family members and to explain how they came to their answer. To further challenge their ability to apply their knowledge, a series of questions about multiple alleles and codominance in animals that are not humans are used. The final part of the lesson makes a link back to module 4 and the correlation between a high proportion of polymorphic gene loci and an increase in genetic diversity. Students will be expected to make links between module 4 and 6 as part of papers 2 and 3, so this demonstrates how exam questions can do just that

This lesson describes the chemical tests for proteins, reducing and non-reducing sugars, starch and lipids and explains how to interpret the results. The PowerPoint and accompanying resource have been designed to cover point 2.1.2 (q) of the OCR A-level Biology A specification. The lesson begins with an explanation of the difference between a qualitative and quantitative test so that the students recognise that the four tests described within this lesson indicate the presence of a substance but not how much. The students are likely to have met these tests at GCSE so this lesson has been planned to build on that knowledge and to add the knowledge needed at this level. A step by step guide walks the students through each stage of the tests for reducing and non-reducing sugars and application of knowledge questions and prior knowledge checks are included at appropriate points to ensure understanding is complete. Time is also taken to ensure that students understand the Science behind the results. The next part of the lesson focuses on the iodine test for starch and the students will learn that the colour change is the result of the movement of an ion into the amylose helix. The rest of the lesson describes the steps in the biuret test for proteins and the emulsion test for lipids. The students will learn that the addition of sodium hydroxide and then copper sulphate will result in a colour change from light blue to lilac if a protein is present and that following the addition of a sample to ethanol and then water, a cloudy emulsion is observed if a lipid is present.

This engaging and fully-resourced lesson looks at how genetic drift can arise after a genetic bottleneck or as a result of the Founder effect. The detailed PowerPoint and accompanying resources have been designed to cover the second part of point 6.1.2 (e) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the factors that affect the evolution of a species. A wide range of examples are used to show the students how a population that descends from a small number of parents will have a reduction in genetic variation and a change in the frequency of existing alleles. Students are encouraged to discuss new information to consider key points and understanding checks in a range of forms are used to enable them to check their progress and address any misconceptions. Students are provided with three articles on Huntington’s disease in South Africa, the Caribbean lizards and the plains bison to understand how either a sharp reduction in numbers of a new population beginning from a handful of individuals results in a small gene pool. Links to related topics are made throughout the lesson to ensure that a deep understanding is gained. This lesson has been designed to tie in with another uploaded lesson on types of selection which is part of this specification point

This detailed lesson describes the role of the mRNA, tRNA, ribosomes and start and stop codons during the second stage of protein synthesis - translation. This lesson is the second in a series of two, which have been designed together to cover point 2.13 of the Edexcel International A-level Biology specification. The first lesson in this series describes transcription. Translation is a topic which is often poorly understood and so this lesson has been written to enable the students to understand how to answer the different types of questions by knowing and including the key details of the structures involved. The lesson begins by challenging the students to consider why it is so important that the amino acids are assembled in the correct order during the formation of the chain. Moving forwards, a quick quiz round called “LOST IN TRANSLATION” is used to check on their prior knowledge of the mRNA strand, the tRNA molecules, the genetic code and the ribosomes. The next task involves a very detailed description of translation that has been divided into 14 statements which the students have to put into the correct order. By giving them a passage that consists of this considerable detail, they can pick out the important parts to use in the next task where they have to answer shorter questions worth between 3 and 4 marks. These types of questions are common in the assessments and by building up through the lesson, their confidence to answer this type should increase. The final two tasks of the lesson involve another quiz, where the teams compete to transcribe and translate in the quickest time before using all that they have learnt to answer some exam-style questions which involve the genetic code and the mRNA codon table.

This fully-resourced lesson describes the relationship between the structure and function of globular proteins, specifically focusing on haemoglobin, insulin and pepsin. The detailed and engaging PowerPoint and accompanying resources have been primarily designed to cover specification point 2.1.2 (n) of the OCR A-level Biology A course but due to the detailed coverage of haemoglobin, the start of this lesson could also be used when teaching lessons that cover specification points 3.1.2 (i) and (j). By the end of the lesson, students will be able to describe that the interactions of the hydrophobic and hydrophilic R groups results in a spherical shape that is soluble in water and be able to explain the importance of this property with reference to the individual functions of these three globular proteins. They will also be able to name key individual details for each protein, such as haemoglobin being a conjugated protein, insulin being linked by numerous disulfide bridges and pepsin’s low number of basic R groups meaning it is stable in the acidic environment of the stomach. Extra time has gone into the planning of this lesson to ensure that links are continuously made to previous topics such as amino acids and the levels of protein structure as well as to upcoming topics like the control of blood glucose concentration that is covered in module 5.1.4.

An engaging lesson presentation (30 slides) that looks at the different methods that are used to treat cardiovascular diseases. The lesson begins by looking at the surgical procedure of heart bypass before exploring the use of stents to widen a partially blocked artery. Links are made back to previous knowledge when discussing valves and students are challenged to explain why a faulty valve must be replaced. The rest of the lesson focusses on treating CVD with medicines such as statins and antiplatelets and students will learn the side-effects associated with these drugs. This lesson has been designed for GCSE students but is suitable for all ages

This detailed lesson describes the principles of DNA sequencing and has been designed to cover the first part of point 6.1.3 (a) of the OCR A-level Biology A specification. Fred Sanger’s chain termination method is used as the example to guide the students through the details of each step. The lesson begins with a focus on the common ingredients of the process such as DNA polymerase, DNA nucleotides and primers. Links are made to module 2.1.3 where nucleic acids were initially met through a series of prior knowledge check questions. Time is then taken to explain why these short lengths of synthesised nucleotides are necessary and this will support students when primers are met in the PCR and genetic engineering. Moving forwards, students will recognise how the modification to the nucleotide means that the chain terminates once a modified nucleotide is added into the sequence and that these have been radioactively labelled. Gel electrophoresis is introduced and an outline of the process given to provide knowledge to build on when this is encountered later in the module. A series of exam-style questions allow students to assess their understanding of this potentially difficult topic before students are encouraged to consider the limitations of the method so they are prepared to meet the new methods in upcoming lessons. A number of quiz competitions run throughout the lesson to maintain engagement and to introduce terms and values in a memorable way

An engaging lesson presentation (61 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B5 (Genes, inheritance and selection) of the OCR Gateway A GCSE Biology specification The topics that are tested within the lesson include: Sexual and asexual reproduction Meiosis Dominant and recessive alleles Genetic crosses The history of genetics Natural selection Classification systems Students will be engaged through the numerous activities including quiz rounds like “Number CRAZY" and “Which Scientist is hidden?” whilst crucially being able to recognise those areas which need further attention

This is an engaging lesson that looks at how vaccinations are used in medicine and considers how the introduction of these preventative measures has reduced the incidence of disease. The lesson begins by introducing vaccinations as the deliberate exposure to antigenic material and then reminds students of the meaning of the term, antigen, so that they understand how this will elicit the desired immune response. Lots of opportunities for discussion have been written into the lesson so that key points such as how the vaccination is altered so that isn’t harmful and how memory cells work can be discussed amongst students before being clarified by the teacher and the lesson content. Moving forwards, students will be given some figures on child mortality rate in 1900 and 2000. They are shown how to manipulate this data in order to work out the percentage change. Students are then challenged to use these skills when comparing the children that were vaccinated for whooping cough in 1968 and 1995 and to make a link between vaccinations and mortality rates. These mathematical skills are being tested more and more in Biology so this guidance will help students to understand how to manipulate data when required. Progress checks have been written into the lesson at regular intervals so that students can constantly assess their understanding. This lesson has been designed for GCSE aged students. If you’re looking for a lesson on this same topic but for older students at A-level, then my upload “Vaccinations (A-level)” will be more suitable

This lesson describes the structure and ultrastructure of plant cells to allow students to compare this structure against animal cell structure. The detailed PowerPoint and accompanying resources have been designed to cover points 4.1 (i) & (ii) in unit 2 of the Edexcel International A-level Biology specification and also describes the functions of the cell wall, chloroplast, amyloplast, vacuole, tonoplast, plasmodesmata, pits and middle lamella The lesson begins with a task called REVERSE GUESS WHO which will challenge the students to recognise a particular organelle from a description of its function. This will remind students that plant cells are eukaryotic and therefore contain a cell-surface membrane, a nucleus (+ nucleolus), a mitochondria, a Golgi apparatus, ribosomes and rough and smooth endoplasmic reticulum like the animal cells. Moving forwards, the next part of the lesson focuses on the relationship between the structure and function of the vacuole, chloroplast, plasmodesmata and cellulose cell wall. When considering the vacuole, key structures such as the tonoplast are described as well as critical functions including the maintenance of turgor pressure. A detailed knowledge of the structure of the chloroplast at this early stage of their A-level studies will increase the likelihood of a clear understanding of photosynthesis when covered in topic 5. For this reason, time is taken to consider the light-dependent and light-independent reactions and to explain how these stages are linked. Students will learn that chloroplasts and amyloplasts can contain stores of starch so an opportunity is taken to challenge them on their knowledge of this polysaccharide as it was covered in topic 1. The final task challenges them to recognise descriptions of the cell wall, chloroplast, amyloplasts, vacuole, tonoplast and plasmodesmata which will leave 2 remaining which describe the pits and middle lamella.

This lesson describes how the cells of multicellular organisms are organised into tissues, tissues into organs and organs into systems. The detailed and engaging PowerPoint and accompanying resources have been designed to cover point 3.13 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification and focuses on the levels of organisation in humans and plants The lesson begins by using the process of haematopoiesis from haematopoietic stem cells to demonstrate how the red blood cell and neutrophil differ significantly in structure despite arising from the same cell along the same cell lineage. A series of exam-style questions will not only challenge their knowledge of structure but also their ability to apply this knowledge to unfamiliar situations. These differences in cell structure is further exemplified by the epithelial cells of the respiratory tract and students are challenged to remember how the shape and arrangement of these cells differ in the trachea and alveoli in relation to their function. The link between specialised cells and tissues is made at this point of the lesson so students are reminded that a tissue is a group of cells that work together to perform a specific function or set of functions. Moving forwards, a quick quiz competition will challenge the students to recognise the liver, kidney, spinal cord and pancreas from a brief functional description and this leads into a series of questions that links back to topics 1 and 2 and earlier in topic 3 where blood clotting, proteins, osmosis, organelles, methods of transport, carbohydrates and enzymes were originally covered. These prior knowledge checks are found throughout the lesson, along with current understanding checks, and all of the mark schemes are embedded into the PowerPoint to allow students to assess their progress. In terms of organ systems, a quick task challenges them to recognise 8 of the 11 that are found in humans from descriptions and this leaves them to identify the gaseous exchange, digestive and reproductive systems as the remaining 3. This leads into a section about cystic fibrosis as this genetic disorder impairs the functioning of these systems. The remainder of the lesson focuses on specialised plant cells and the differing shapes and features of the palisade and spongy cells in the mesophyll layer and the guard cells are covered at length and in detail. The cells found in the xylem and phloem tissue are also discussed.

This lesson describes the meaning of the term stem cell and the differences between totipotent, pluripotent and multipotent stem cells. The PowerPoint and accompanying worksheets have been designed to cover points 7.3 (i) and (ii) of the Edexcel A-level Biology B specification meaning that this lesson also contains discussion periods about the potential opportunities to use stem cells from embryos in medicine. The lesson begins with a knowledge recall of the structure of eukaryotic cells and the students have to use the first letters of each of the four answers to reveal the key term, stem cell. Time is then taken to consider the meaning of cellular differentiation, and this leads into the key idea that not all stem cells are equal when it comes to the number of cell types that they have the potential to differentiate into. A quick quiz round introduces the five degrees of potency, and then the students are challenged to use their understanding of terminology to place totipotency, pluripotency, multipotency, oligopotency and unipotency in the correct places on the potency continuum. Although the latter two do not have to be specifically known based on the content of specification point 7.3 (i), an understanding of their meaning was deemed helpful when planning the lesson as it should assist with the retention of knowledge about totipotency, pluripotency and multipotency. These three highest degrees of potency are the main focus of the lesson, and key details are emphasised such as the ability of totipotent cells to differentiate into any extra-embroyonic cell, which the pluripotent cells are unable to do. The morula, and inner cell mass and trophoblast of the blastocyst are used to demonstrate these differences in potency. The final part of the lesson discusses the decisions that the scientific community have to make about the use of pluripotent embryonic stem cells, adult stem cells and also multipotent foetal stem cells As there is a heavy mathematical content in the current A-level Biology exams, a Maths in a Biology context question is included in the lesson (when introducing the morula) to ensure that students continue to be prepared for the numerous calculations that they will have to tackle in the terminal exams. This resource has been differentiated two ways to allow students of differing abilities to access the work

A fully resourced lesson which includes an informative lesson presentation (25 slides) and an associated worksheet that show students how to give answers to a certain number of significant figures. The answers to questions in Science are often required to be given in significant figures and this lesson guides students through this process, including the rules of rounding that must be applied for success to be likely. This lesson has been designed for GCSE students but is suitable for KS3

A detailed lesson which looks at the type of cell division known as mitosis and aims to ensure that students understand that it leads to the production of genetically identical daughter cells. In order to understand this type of cell division and any related topic such as meiosis, students have to be confident with the use of terms like diploid. In addition to this, time is taken to introduce them to a way of considering the quantity of DNA within a cell in terms of n. If they are able to use this correctly, then no matter the organism which is involved in a mitosis exam question, they will be able to answer successfully. Discussion points and progress checks are written into the lesson at regular intervals so their understanding can be assessed. The last part of the lesson provides the students with an opportunity to apply their knowledge of mitosis to a range of exam questions and they can assess against the displayed mark schemes. This lesson has been designed for GCSE students (14 - 16 year olds in the UK) but is also appropriate for older students who want to recap on the key details of the division before extended knowledge is added.

This lesson describes how the recent use of similarities in biological molecules and other genetic evidence has led to new classification systems. The PowerPoint and accompanying resources have been designed to cover point 4.2.2 [c] (i) of the OCR A-level Biology A specification and focuses on the introduction of the three-domain system following Carl Woese’s detailed study of the ribosomal RNA gene. The lesson begins with an introduction of Woese and goes on to describe how he is most famous for his definition of the Archaea as a new domain of life. Students were introduced to domains and the other classification taxa in a previous lesson, so their recall of this knowledge is continually tested and built upon as details are added. Students will discover the key differences between Archaea and Bacteria that led to the splitting of the prokaryotae kingdom and the addition of this higher classification rank. Moving forwards, the rest of the lesson considers other molecules that can be compared between species for classification purposes and the primary structure of cytochrome is described and discussed. At this point in the lesson, the students are also tested on their knowledge of the nature of the genetic code and have to explain how mutations to DNA can also be used for comparative purposes.

An engaging and detailed lesson presentation (31 slides) that looks at how nitrogen is cycled and focuses on the different bacteria who play key roles in this cycle. The lesson begins by exploring why nitrogen is so critical for living organisms for the synthesis of DNA and proteins. Students are introduced to nitrogen-fixing bacteria to start and challenged to use their knowledge of interdependence to state the type of ecological relationship that is formed between them and the leguminous plant that they live on. Each stage of the cycle is complimented by a diagram highlighting that part so students are able to visualise how the cycle comes together. Time is taken to ensure that students recognise that any non-leguminous plants can only absorb nitrogen when it is nitrates form from the soil. Moving forwards, students will meet decomposers and nitrifying bacteria and again be shown where their function fits into the cycle. As the final part of the learning, students are challenged to consider what else is needed in order for this to be a cycle and will meet the denitrifying bacteria as a result. Progress checks, in a range of forms, have been written into this lesson at regular intervals so that students can assess their understanding and any misconceptions can be immediately addressed. This lesson has been written for GCSE students, but could be used with A-level students who want to have a recap before extending their knowledge further.

This engaging lesson guides students through the homeostatic control mechanism which is involved in controlling blood glucose concentrations and focuses on the critical interconversion between glucose and glycogen which is often poorly understood. The lesson begins by introducing glucose and ensuring that students recognise that this is a simple sugar which is critical for respiration. Links are made here and throughout the lesson to relateable topics such as the endocrine system so that students can recognise how exam questions will often encompass more than one topic. Students are challenged to recall knowledge about the pancreas and its release of insulin into the blood to travel to the liver. A quick competition is then used to maintain engagement and to introduce glycogen. Due to the large number of words beginning with g that are involved in this topic, time is taken to describe the role of glycogen so that it is not mistaken for glucose or glucagon. Students will learn how the conversion from glucose to glycogen and also the other way round is critical to how the concentration is controlled. The main student tasks involve them completing a partially finished passage about responding to an increase in blood glucose concentration and then using this as a guide to write their own full versions for when concentrations are low. These are just two of a number of progress checks that are written into the lesson at regular intervals so that students can constantly assess their understanding. This lesson has been written for GCSE students (14 - 16 year olds in the UK) but could be used for A-level lessons that are recapping on this topic before extra knowledge is added at this higher level

This fully-resourced lesson describes the relationship between the properties and functions of the fibrous proteins, collagen, keratin and elastin. The detailed PowerPoint and accompanying resources have been designed to cover point 2.1.2 (o) of the OCR A-level Biology A specification but also make links to upcoming topics such as blood vessel structure and the immune system as well as constantly challenging students on their knowledge of proteins from earlier in this module. The lesson begins by challenging the students to recognise 7 structures found in animals from their descriptions and once they’ve written feathers, cartilage, bones, arteries, tendons, callus and skin into the right places, they will reveal the term fibrous and learn that these types of protein are found in these structures. Using their knowledge of the properties of globular proteins, they will learn that the insolubility of fibrous proteins allows them to form fibres, which perform structural functions. The rest of the lesson focuses on the functions of collagen, keratin and elastin and time is taken to discuss the key details and to make links to future topics so that students can recognise the importance of cross-modular based answers. A series of exam-style questions are used to challenge their knowledge of protein structure as well as their ability to apply their knowledge to an unfamiliar situation when learning that elastin is found in the walls of the urinary bladder. All of the questions have mark schemes embedded into the PowerPoint to allow them to immediately assess their understanding. This lesson has been specifically planned to tie in with the previous lesson on globular proteins as well as the one preceding that on the structures of proteins

This fully-resourced lesson focuses on the role of meiosis in ensuring genetic variation through the production of non-identical gametes. The detailed PowerPoint and accompanying resource have been designed to cover point 3.9 of the Pearson Edexcel A-level Biology (Salters Nuffield) specification which states that students should be able to describe how crossing over and independent assortment result in genetically unidentical daughter cells. In order to understand how the events of meiosis like crossing over and random assortment and independent segregation can lead to variation, students need to be clear in their understanding that DNA replication in interphase results in homologous chromosomes as pairs of sister chromatids. Therefore the beginning of the lesson focuses on the chromosomes in the parent cell and this first part of the cycle and students will be introduced to non-sister chromatids and the fact that they may contain different alleles which is important for the exchange that occurs during crossing over. Time is taken to go through this event in prophase I in a step by step guide so that the students can recognise that the result can be new combinations of alleles that were not present in the parent cell. Moving forwards, the lesson explores how the independent segregation of chromosomes and chromatids during anaphase I and II results in genetically different gametes. The final part of the lesson looks at the use of a mathematical expression to calculate the possible combinations of alleles in gametes as well as in a zygote following the random fertilisation of haploid gametes. Understanding and prior knowledge checks are interspersed throughout the lesson as well as a series of exam questions which challenge the students to apply their knowledge to potentially unfamiliar situations.