This fully-resourced lesson explores how new species arise when changes in the gene pool of two populations prevents members from interbreeding and producing fertile offspring. The engaging PowerPoint and accompanying resources have been designed to cover the fifth part of point 7.3 of the AQA A-level Biology specification which states that students should be able to describe allopatric and sympatric speciation. The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.

This is a detailed, engaging and fully-resourced REVISION LESSON which allows students of all abilities to assess their understanding of the content in module 2.1.3 (Nucleotides and nucleic acids) of the OCR A-level Biology A specification. Considerable time has been taken to design the lesson to include a wide range of activities to motivate the students whilst they evaluate their knowledge of DNA, RNA and the roles of these nucleic acids in DNA replication and protein synthesis. Most of the tasks have been differentiated so that students of differing abilities can access the work and move forward as a result of the tasks at hand. This lesson has been planned to cover as much of the specification as possible but the following sub-topics have received particular attention: The structure of DNA Phosphorylated nucleotides DNA replication Transcription and translation Gene mutations and their affect on the primary structure of a polypeptide The structure of RNA In addition to a focus on the current topic, links are made throughout the lesson to other topics such as the journey of an extracellular protein following translation and the cell cycle. If you like the quality of this revision lesson, please look at the other uploaded revision lessons for this module and for this specification

An engaging lesson presentation (61 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B2 (Organisation) of the AQA GCSE Biology specification (specification point 4.2) The topics that are tested within the lesson include: Principles of organisation The human digestive system The heart and blood vessels Blood Coronary heart disease The effect of lifestyle on some non-communicable diseases Plant organ systems Students will be engaged through the numerous activities including quiz rounds like “SPOT the SUBSTANCE" and “Where’s LENNY” whilst crucially being able to recognise those areas which need further attention

This lesson has been designed to guide GCSE students (14 - 16 year olds in the UK) through the steps involved in gas calculations. As you can see in the cover image, this lesson uses a step by step guide format to go through each of the critical stages. Hints and tips are given along the way and worked examples are used so that students can visualise how to set out their working. Important terminology such as room temperature and pressure (RTP) and limiting reactant are explained so that these do not cause issues. Students are given the opportunity to test their skills against some gas calculation questions which have detailed mark schemes and explanations to enable them to fully self-assess.

This lesson guides students through the use of the chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated worksheets that have been designed to cover point 6.1.2 © of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the test to compare the observed and expected results of a genetic cross The lesson has been written to include a step-by-step guide that demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty.

This detailed lesson describes how the structure of a prokaryotic cell differs from the structure of an eukaryotic cell. The engaging PowerPoint and accompanying resources have been designed to cover the first part of point 2.1.2 of the AQA A-level Biology specification and describes how the size and cell structures differ and also covers the additional features that are found in some prokaryotic cells. A clear understanding of terminology is important for A-level Biology so this lesson begins with a challenge, where the students have to add an additional prefix to their prefix and suffix table which they believe will translate as before or in front of. This leads into the discovery of the meaning of prokaryote as before nucleus and this acts to remind students that these types of cell lack this cell structure. Links to the previous lessons on the eukaryotic cells are made throughout the lesson and at this particular point, the students are asked to work out why the DNA would be described as naked and to state where it will be found in the cell. Moving forwards, the students will discover that these cells also lack membrane bound organelles and a quick quiz competition challenges them to identify the specific structure that is absent from just a single word. In addition to the naked DNA, students will learn that there are also ribosomes in the cytoplasm and will discover that these are smaller than those found in the cytoplasm of an eukaryotic cell (but the same size as those in chloroplasts and mitochondria). The remainder of the lesson focuses on the composition of the cell wall, the additional features of prokaryotic cells such as plasmids and there is also the introduction of binary fission as the mechanism by which these organisms reproduce.

This fully-resourced lesson describes the roles of the platelets and plasma proteins in the sequence of events that lead to blood clotting. The engaging PowerPoint and accompanying resources have been primarily designed to cover the content detailed in point 4.4 (viii) of the Edexcel A-level Biology B specification and includes descriptions of the roles of thromboplastin, thrombin and fibrin but time has also been taken to look at haemophilia as a sex-linked disease so that students are prepared for topic 8 (genetic variation). The lesson begins with the introduction of clotting factors as integral parts of the blood clotting process and explains that factor III, thromboplastin, needs to be recalled as well as the events that immediately precede and follows its release. Students will learn how damage to the lining and the exposure of collagen triggers the release of this factor and how a cascade of events then results. Quick quiz rounds and tasks are used to introduce the names of the other substances involved which are prothrombin, thrombin, fibrinogen and fibrin. In a link to the upcoming topic of proteins, students will understand how the insolubility of fibrin enables this mesh of fibres to trap platelets and red blood cells and to form the permanent clot. The final part of the lesson introduces haemophilia as a sex-linked disease and students are challenged to apply their knowledge to an unfamiliar situation as they have to write genotypes and determine phenotypes before explaining why men are more likely to suffer from this disease than women.

This fully-resourced REVISION LESSON has been designed to provide the students with numerous opportunities to assess their understanding of the content of module 5.2.2 (Respiration) of the OCR A-level Biology A specification. The importance of this metabolic reaction is obvious and this is reflected in the volume of questions in the terminal exams which require an in depth knowledge of the stages of both aerobic and anaerobic respiration. The lesson contains a wide range of activities that cover the following points of the specification: Glycolysis as a stage of aerobic and anaerobic respiration The use and production of ATP through respiration Anaerobic respiration in mammalian muscle tissue The stages of aerobic respiration that occur in the mitochondrial matrix Oxidative phosphorylation The use of respirometers Calculating the respiratory quotient value for different respiratory substrates Revision lessons which cover the other sub-modules of module 5 are uploaded and tie in well with this content

This is a fully-resourced revision lesson that includes a detailed and engaging powerpoint (81 slides) that uses a combination of exam questions, understanding checks, quick differentiated tasks and quiz competitions to enable students to assess their understanding of the content found within Topic 8 (Grey Matter) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification. The specification points that are tested within the lesson include: Know the structure and function of sensory, relay and motor neurones including the role of Schwann cells and myelination. Understand how the nervous systems of organisms can cause effectors to respond to a stimulus. Understand how the pupil dilates and contracts. Understand how a nerve impulse (action potential) is conducted along an axon including changes in membrane permeability to sodium and potassium ions and the role of the myelination in saltatory conduction. Know the structure and function of synapses in nerve impulse transmission, including the role of neurotransmitters, including acetylcholine. Understand how IAA bring about responses in plants to environmental cues Know the location and functions of the cerebral hemispheres, hypothalamus, cerebellum and medulla oblongata in the human brain. Understand how magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), positron emission tomography (PET) and computed tomography (CT) scans are used in medical diagnosis and the investigation of brain structure and function. Understand how imbalances in certain, naturally occurring brain chemicals can contribute to ill health, including dopamine in Parkinson’s disease and serotonin in depression, and to the development of new drugs. Understand the effects of drugs on synaptic transmissions, including the use of L-Dopa in the treatment of Parkinson’s disease and the action of MDMA in Ecstasy. Students will be engaged by the numerous quiz rounds such as “From NUMBERS 2 LETTERS” and “COMMUNICATE the WORD” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

This fully-resourced lesson explores how the presence of particular alleles at one locus can mask the expression of alleles at a second locus in epistasis. The detailed and engaging PowerPoint and associated resources have been designed to cover the part of point 6.1.2 (b[ii]) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the use of phenotypic ratios to identify epistasis. This is a topic which students tend to find difficult, and therefore the lesson was written to split the topic into small chunks where examples of dominant, recessive and complimentary epistasis are considered, discussed at length and then explained. Understanding checks, in various forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed. There are regular links to related topics such as dihybrid inheritance so that students can meet the challenge of interpreting genotypes as well as recognising the different types of epistasis.

A fully resourced revision lesson which uses a range of exam questions (with explained answers), quick tasks and quiz competitions to enable the students to assess their understanding of the topics found within module 6.3.1 (Ecosystems) of the OCR A-level Biology A specification. The topics tested within this lesson include: Ecosystems Transfer of biomass Recycling within ecosystems Succession Studying ecosystems Student will enjoy the range of tasks and quiz rounds whilst crucially being able to recognise any areas which require further attention

This revision lesson contains an engaging powerpoint (45 slides) and associated worksheets that are incorporated into the lesson to challenge and consolidate the learning. The lesson has been designed to contain a wide range of activities so that students remain motivated and engaged whilst they assess their understanding of the content found in Biology topic 3 (Infection and response) of the AQA GCSE Combined Science specification (Trilogy 9-1) The exam questions, differentiated tasks and quiz competitions found within the lesson challenge the following specification topics: Communicable (infectious) diseases Viral diseases Bacterial diseases Fungal diseases Protist diseases The Human defence system Vaccinations Antibiotics Students will be able to use the lesson to identify the areas of the specification that require further attention and this lesson can be used at the end of the topic, in the lead up to the mocks or in the lead up to the actual GCSE exams.

This fully-resourced looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration effects the dissociation of adult oxyhaemoglobin. The PowerPoint and accompanying resources have been designed to cover point 8.1 (g) of the CIE International A-level Biology specification and continually ties in with the previous lesson on the role of haemoglobin in carrying oxygen. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual.

This fully-resourced lesson looks at the double, closed circulatory system as found in a mammal and considers how the pulmonary circulation differs from the systemic circulation. The engaging PowerPoint and accompanying resources have been designed to cover point 8.1 (a) of the CIE International A-level Biology specification The lesson begins with a focus on the meaning of a double circulatory system and checks that students are clear in the understanding that the blood passes through the heart twice per cycle of the body. Beginning with the pulmonary circulation, students will recall that the pulmonary artery carries the blood from the right ventricle to the lungs. An opportunity is taken at this point to check on their knowledge of inhalation and the respiratory system as well as the gas exchange between the alveoli and the capillary bed. A quick quiz is used to introduce arterioles and students will learn that these blood vessels play a crucial role in the changes in blood pressure that prevent the capillaries from damage. When looking at the systemic circulation, time is taken to look at the coronary arteries and renal artery as students have to be aware of these vessels in addition to the ones associated with the heart. In the final part of the lesson, students are challenged to explain how the structure of the heart generates a higher pressure in the systemic circulation and then to explain why the differing pressures are necessary. As a result of the constant reference to the heart, the blood vessels and the blood, students will be reminded that these are the components of the circulatory system

This fully-resourced lesson has been designed to cover the content of specification point 5.2.2 (The brain) as found in topic 5 of the AQA GCSE Biology specification. This resource contains an engaging PowerPoint (33 slides) and accompanying worksheets, some of which have been differentiated so that students of different abilities can access the work. The resource is filled with a wide range of activities, each of which has been designed to engage and motivate the students whilst ensuring that the key Biological content is covered in detail. Understanding checks are included throughout so that the students can assess their grasp of the content. In addition, previous knowledge checks make links to content from earlier topics such as cancer. The following content is covered in this lesson: The functions of the cerebral cortex, medulla and cerebellum Identification of the regions of the brain on an external and internal diagram The early use of stroke victims to identify functions The key details of the MRI scanning technique The difficulties of diagnosing and treating brain disorders and disease As stated at the top, this lesson has been designed for GCSE-aged students who are studying the AQA GCSE Biology course, but it can be used with A-level students who need to go back over the key points before looking at the functionality of the regions in more detail

This lesson describes the roles of the buccal cavity, operculum, gill lamellae and countercurrent flow in ventilation and gas exchange in bony fish. The detailed PowerPoint and accompanying resources are part of the first lesson in a series of 2 that have been designed to cover the details of point 3.1.1 (f) of the OCR A-level Biology A specification. The second lesson in this series covers the mechanisms of ventilation and gas exchange in insects. The lesson has been specifically planned to prepare students for the content of module 3.1.2 (Transport in animals) and therefore begins with an introduction and a brief description of the single circulatory system of a fish as this has an impact on the delivery of deoxygenated blood to the lamellae. A quick quiz competition is used to introduce the operculum and then the flow of blood along the gill arch and into the primary lamellae and then into the capillaries in the secondary lamellae is described. The next task challenges the students to use their knowledge of module 2 to come up with the letters that form the key term, countercurrent flow. This is a key element of the lesson and tends to be a feature that is poorly understood, so extra time is taken to explain the importance of this mechanism. Students are shown two diagrams, where one contains a countercurrent system and the other has the two fluids flowing in the same direction, and this is designed to support them in recognising that this type of system ensures that the concentration of oxygen is always higher in the oxygenated water than in the blood in the lamellae. The remainder of the lesson focuses on the coordinated movements of the buccal-opercular pump to ensure that the water continues to flow over the gills. Current understanding and prior knowledge checks are included throughout the lesson and students can assess their progress against the mark schemes which are embedded into the PowerPoint

This fully-resourced lesson guides students through the use of the Hardy-Weinberg equation to calculate the frequency of alleles, genotypes and phenotypes in a population. Both the detailed PowerPoint and differentiated practice questions on a worksheet have been designed to cover the 2nd part of point 7.2 of the AQA A-level Biology specification which expects students to be able to use this mathematical model The lesson begins by looking at the equation and ensuring that students understand the meaning of each of the terms. The recessive condition, cystic fibrosis, is used as an example so that students can start to apply their knowledge and assess whether they understand which genotypes go with which term. Moving forwards, a step-by-step guide is used to show students how to answer a question. Tips are given during the guide so that common misconceptions and mistakes are addressed immediately. The rest of the lesson gives students the opportunity to apply their knowledge to a set of 3 questions, which have been differentiated so that all abilities are able to access the work and be challenged.

This engaging and fully-resourced lesson looks at the myogenic nature of cardiac muscle and explores the roles of the SAN, AVN and Purkyne tissue in the initiation and control of heart action. The PowerPoint and accompanying resources have been designed to cover points 8.2 (d) of the CIE International A-level Biology specification. The lesson begins with the introduction of the SAN as the natural pacemaker and then time is given to study each step of the conduction of the impulse as it spreads away from the myogenic tissue in a wave of excitation. The lesson has been written to make clear links to the cardiac cycle and the structure of the heart and students are challenged on their knowledge of this system from topic 8.1. Moving forwards, students are encouraged to consider why a delay would occur at the AVN and then they will learn that the impulse is conducted along the Bundle of His to the apex so that the contraction of the ventricles can happen from the bottom upwards. The structure of the cardiac muscle cells is discussed and the final task of the lesson challenges the students to describe the conducting tissue, with an emphasis on the use of key terminology Due to the detailed nature of this lesson, it is estimated that it will take about 2 hours of A-level teaching time to cover the detail

This engaging lesson looks at the role of haemoglobin in carrying oxygen and carbon dioxide. The PowerPoint has been designed to cover point 8.1 (f) of the CIE International A-level Biology specification and includes references to the role of carbonic anhydrase and the formation of haemoglobinic acid and carbaminohaemoglobin. The lesson begins with a version of the quiz show Pointless to introduce haemotology as the study of the blood conditions. Students are told that haemoglobin has a quaternary structure and are challenged to use their prior knowledge of biological molecules to determine what this means for the protein. They will learn that each of the 4 polypeptide chains contains a haem group with an iron ion attached and that it is this group which has a high affinity for oxygen. Time is taken to discuss how this protein must be able to load (and unload) oxygen as well as transport the molecules to the respiring tissues. Students will plot the oxyhaemoglobin dissociation curve and the S-shaped curve is used to encourage discussions about the ease with which haemoglobin loads each molecule. The remainder of the lesson looks at the different ways that carbon dioxide is transported around the body that involve haemoglobin. Time is taken to look at the dissociation of carbonic acid into hydrogen ions so that students can understand how this will affect the affinity of haemoglobin for oxygen in an upcoming lesson on the Bohr effect.

An engaging lesson presentation (57 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within module P6 (Global challenges) of the OCR Gateway A GCSE Combined Science specification. The topics that are tested within the lesson include: Everyday motion Reaction time and thinking distance Braking distance and stopping distance Energy sources The National Grid Mains electricity Students will be engaged through the numerous activities including quiz rounds like “Can you go the DISTANCE” whilst crucially being able to recognise those areas which need further attention