A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
This lesson describes the main stages of meiosis and has a specific focus on those events which contribute to genetic variation. The detailed PowerPoint and accompanying resources have been designed to cover point (d) in topic 6 of AS unit 1 of the WJEC A-level Biology specification and includes description of crossing over, independent assortment, independent segregation and the production of haploid gametes
In order to understand how the events of meiosis like crossing over and independent assortment and independent segregation can lead to variation, students need to be clear in their understanding that DNA replication in interphase results in homologous chromosomes as pairs of sister chromatids. Therefore the beginning of the lesson focuses on the chromosomes in the parent cell and this first part of the cycle and students will be introduced to non-sister chromatids and the fact that they may contain different alleles which is important for the exchange that occurs during crossing over. Time is taken to go through this event in prophase I in a step by step guide so that the students can recognise that the result can be new combinations of alleles that were not present in the parent cell. Moving forwards, the lesson explores how the independent assortment and segregation of chromosomes and chromatids during metaphase I and II and anaphase I and II respectively results in genetically different gametes. The key events of all of the 8 phases are described and there is a focus on key terminology to ensure that students are able to describe genetic structures in the correct context. The final part of the lesson looks at the use of a mathematical expression to calculate the possible combinations of alleles in gametes as well as in a zygote following the random fertilisation of haploid gametes. Understanding and prior knowledge checks are interspersed throughout the lesson as well as a series of exam-style questions which challenge the students to apply their knowledge to potentially unfamiliar situations.
This lesson has been specifically planned to lead on from the previous two lessons on the cell cycle and the main stages of mitosis and constant references are made throughout to encourage students to make links and also to highlight the differences between the two types of nuclear division
This lesson describes the main stages of mitosis and explains the significance of this type of nuclear division for the daughter cells produced by the cycle. The PowerPoint and accompanying resources have been designed to cover points 6 (a & b) in topic 6 of AS unit 1 of the WJEC A-level Biology specification and the process of cytokinesis is also described.
Depending upon the exam board taken at GCSE, the knowledge and understanding of mitosis will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson so that existing errors are addressed and key points are emphasised throughout. Their understanding of interphase is challenged at the start of the lesson to ensure that they realise that it is identical pairs of sister chromatids that enter the M phase. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. There is a focus on the centrioles and the spindle fibres that they produce which contract to drag one chromatid from each pair in opposite directions to the poles of the cell. The remainder of the lesson is a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final quiz round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture.
This lesson describes the key events of the eukaryotic cell cycle and specifically focuses on those that occur in interphase. The PowerPoint and accompanying resources have been designed to cover point (a) in topic 6 of AS unit 1 of the WJEC A-level Biology specification and also introduces the stages of mitosis and cytokinesis to prepare students for the upcoming lesson on the significance of this type of cell division.
The students were introduced to the cell cycle at GCSE so this lesson has been planned to build on that knowledge and to emphasise that the M phase which includes mitosis (nuclear division) only occupies a small part of the cycle. The students will learn that interphase is the main stage and that this is split into three phases, G1, S and G2. A range of tasks which include exam-style questions, guided discussion points and quick quiz competitions are used to introduce key terms and values and to describe the main processes that occur in a very specific order. Extra time is taken to ensure that key terminology is included and understood, such as sister chromatid and centromere, and this focus helps to show how it is possible for genetically identical daughter cells to be formed at the end of the cycle.
This lesson describes how the action of the radial and circular muscles of the iris causes the pupil to dilate or contract. The PowerPoint has been designed to cover point 8.6 (ii) of the Edexcel International A-level Biology specification and includes key details such as the innervation of the smooth muscles by divisions of the autonomic nervous system.
Students will learn how:
the contraction of the radial muscles pulls the iris radially and enlarges the pupil, allowing more light to enter when an individual is in a room with dim light and that this contraction is the result of the conduction of an electrical impulse along a sympathetic motor neurone.
the contraction of the circular muscles constricts the pupil to reduce the light that enters the eye, in order to prevent damage to the photosensitive cells in the retina. This is the result of innervation by an impulse conducted along a parasympathetic neurone
This lesson describes how the antagonistic action of the radial and circular muscles of the iris causes the pupil to dilate or contract. The PowerPoint has been designed to cover point 8.2 (ii) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification.
The students may have encountered this concept at GCSE, so this lesson has been written to build on that knowledge and includes key A-level details such as the innervation of the smooth muscles by divisions of the autonomic nervous system. Students will learn how the contraction of the radial muscles pulls the iris radially and enlarges the pupil, allowing more light to enter when an individual is in a room with dim light and that this contraction is the result of the conduction of an electrical impulse along a sympathetic motor neurone.
This bundle contains 8 fully-resourced lessons which have been designed to cover the following content in topic 8 of the Edexcel International A-level Biology specification:
8.1: Know the structure and function of sensory, relay and motor neurones
8.2: Understand how the nervous system of organisms can cause effectors to respond to a stimulus
8.4: Understand how a nerve impulse is conducted along an axon
8.5: Understand the role of myelination in saltatory conduction
8.6 (i): Know the structure and function of synapses in nerve impulse transmission
8.6 (ii): Understand how the pupil dilates and contracts
8.8: Understand how the nervous system of organisms can detect stimuli with reference to rods in the retina of mammals
8.10: Know that the mammalian nervous system consists of the central and peripheral nervous systems
8.13: Understand how coordination in animals is brought about through nervous and hormonal control
8.18: Understand how recombinant DNA can be produced
8.19: Understand how recombinant DNA can be inserted into other cells
Each of the lessons contains a wide range of activities, which include exam-style questions, guided discussion periods and quick quiz competitions, and these will motivate the students whilst the difficult A-level content is covered
If you would like to see the quality of lessons included in this bundle then download the pupil reflex, saltatory conduction and nervous and hormonal control lessons as these have been uploaded for free
This detailed lesson describes how recombinant DNA is produced using restriction endonucleases and DNA ligase and is inserted into other cells. The engaging PowerPoint and accompanying resources have been designed to cover points 8.18 & 8.19 of the Edexcel International A-level Biology specification.
The lesson begins with a definition of genetic engineering and recombinant DNA to allow students to begin to understand how this process involves the transfer of DNA fragments from one species to another. Links are made to the genetic code and transcription and translation mechanisms, which were met in topic 2, in order to explain how the transferred gene can be translated in the transgenic organism. Moving forwards, the method involving reverse transcriptase and DNA polymerase is introduced and their knowledge of the structure of the polynucleotides and the roles of enzymes is challenged through questions and discussion points. Restriction endonucleases are then introduced and time is taken to look at the structure of a restriction site as well as the production of sticky ends due to the staggered cut on the DNA. A series of exam-style questions with displayed mark schemes are used to allow the students to assess their current understanding.
The second half of the lesson looks at the culture of transformed host cells as an in vivo method to amplify DNA fragments. Students will learn that bacterial cells are the most commonly transformed cells so the next task challenges their recall of the structures of these cells so that plasmid DNA can be examined from that point onwards.
Time is taken to explore the finer details of each step such as the addition of the promoter and terminator regions, use of the same restriction enzyme to cut the plasmid as was used to cut the gene and the different types of marker genes.
As well as understanding and prior knowledge checks, quick quiz competitions are used throughout the lesson to introduce key terms such as cDNA and EcoR1 in a fun and hopefully memorable way
This lesson describes how the nervous system allows effectors to respond to stimuli and also describes hormonal control in animals. The PowerPoint and accompanying resources have been primarily designed to cover points 8.2 & 8.13 of the Edexcel International A-level Biology specification but it can also be used as a revision lesson as there are numerous prior knowledge checks of muscle contraction, protein structure and the control of gene expression.
The lesson begins by challenging the students to recall that a control system contains sensory receptors, a coordination centre and effectors. Sensory receptors are covered in detail later in the topic when some key examples are considered as well as those in the retina, but time is taken now to describe how these structures act like transducers, converting one form of energy into electrical energy and the Pacinian corpuscle is used as an example. The students will learn that the communication between the receptors and the coordination centre and the effectors is by cell signalling and that the effectors can be muscles which contract or glands that release chemicals. The next part of the lesson looks at the differing responses from the nervous and hormonal systems and discusses how this can be governed by the need for a rapid response or more of a long term effect. In terms of nervous control, the students are challenged on their recall of the sliding filament theory of muscle contraction as covered in topic 7. Moving forwards, the students will learn that hormones can be either peptide or steroid hormones and their action at a target cell differs based on their form. Students are tested on their knowledge of protein structure by a series of exam-style questions on insulin and glucagon. They are reminded that steroid hormones can pass directly through the cell membrane and their knowledge of the control of gene expression by transcription factors is tested through a task involving oestrogen and the ER receptor. The lesson concludes by reminding students that the control of heart rate, as covered in topic 7, is a coordinated response that involves both nervous and hormonal control.
This lesson describes the structure and function of synapses in nerve impulse transmission and focuses on acetylcholine as a neurotransmitter. The PowerPoint and accompanying resources have been designed to cover point 8.6 (i) of the Edexcel International A-level Biology specification, using a cholinergic synapse as the main example
The lesson begins by using a version of the WALL from “Only Connect” which asks the students to group 12 words into three groups of 4. Not only will this challenge their prior knowledge from topics earlier in this topic but it will also lead to the discovery of four of the structures that are found in a synapse. Moving forwards, students are introduced to acetylcholine as the neurotransmitter involved at cholinergic synapses and they will start to add labels to the structures found in the pre-synaptic bulb. Time is taken to focus on certain structures such as the voltage gated channels as these types of channel were met previously when looking at the depolarisation of a neurone. There is plenty of challenge and discovery as students are pushed to explain why organelles like mitochondria would be found in large numbers in the bulb. With this process being a cascade of events, a bullet point format is used to ensure that the key content is taken in by the students and again key points like exocytosis and the action of acetylcholinesterase are discussed further.
Understanding checks and prior knowledge checks are included throughout the lesson so that students can not only assess their progress against the current topic but also see whether they can make links to earlier topics.
This lesson describes the role of myelination in saltatory conduction. The PowerPoint and accompanying worksheet have been designed to cover point 8.5 of the Edexcel International A-level Biology specification and includes constant references to the earlier lessons on the structure of neurones and the conduction of an action potential along an axon.
A wide range of activities have been written into this resource to maintain the motivation of the students whilst ensuring that the detail is covered in depth. Interspersed with the activities are understanding checks and prior knowledge checks to allow the students to not only assess their understanding of the current topic but also challenge themselves to make links to earlier topics such as the movement of ions across membranes and biological molecules. Time at the end of the lesson is also given to future knowledge such as the involvement of autonomic motor neurones in the stimulation of involuntary muscles.
Over the course of the lesson, students consider the structure of the myelin sheath and specifically how the insulation is not complete all the way along which leaves gaps known as the nodes of Ranvier which allow the entry and exit of ions. Saltatory conduction tends to be poorly explained by students so time is taken to look at the way that the action potential jumps between the nodes and this is explained further by reference to local currents. The rest of the lesson focuses on the other two factors which are axon diameter and temperature and students are challenged to discover these two by focusing on the vampire squid.
This lesson explains how a nerve impulse (action potential) is conducted along an axon and focuses on the role of the sodium and potassium ions. The PowerPoint and accompanying resources have been designed to cover point 8.4 of the Edexcel International A-level Biology specification and contains detailed descriptions of resting potential, depolarisation, repolarisation, hyperpolarisation and the refractory period.
This topic is commonly assessed in the terminal exams so extensive planning ensures that this resource includes a wide range of activities to motivate and engage the students whilst ensuring that the content is covered in the depth of detail that will allow them to have a real understanding. Interspersed within the activities are understanding checks and prior knowledge checks to enable the students to not only assess their progress against the current topic but also to challenge themselves on the links to earlier topics such as methods of movements across cell membranes. There are also a number of quiz competitions which are used to introduce key terms and values in a fun and memorable way and discussion points to encourage the students to consider why a particular process or mechanism occurs.
Over the course of the lesson, the students will learn and discover how the movement of ions across the membrane causes the membrane potential to change. They will see how the resting potential is maintained through the use of the sodium/potassium pump and potassium ion leakage. There is a real focus on depolarisation to allow students to understand how generator potentials can combine and if the resulting depolarisation then exceeds the threshold potential, a full depolarisation will occur. At this point in the lesson students will discover how the all or nothing response explains that action potentials have the same magnitude and that instead a stronger stimulus is linked to an increase in the frequency of the transmission. The rest of the lesson challenges the students to apply their knowledge to explain how repolarisation and hyperpolarisation result and to suggest advantages of the refractory period for nerve cells.
This lesson bundle contains 4 lessons, which are fully-resourced and are filled with a range of tasks to engage and motivate the students whilst covering the following specification points in topic 10 of the CIE A-level Biology specification:
10.1
[a]: Define the term disease and explain the difference between an infectious disease and a non-infectious disease
[b]: State the name and type of causative organism of cholera, malaria, TB, HIV/AIDS, smallpox and measles
[c]: Explain how cholera, malaria, TB and HIV are transmitted
10.2
[a]: Outline how penicillin acts on bacteria and why antibiotics do not affect viruses
[b]: Explain in outline how bacteria becomes resistant to antibiotics with reference to mutation and selection
[c]: Discuss the consequences of antibiotic resistance and the steps that can be taken to reduce its impact
Included in the tasks are exam-style questions, and the mark schemes for each of these are embedded into the PowerPoint to allow the students to assess their progress
This lesson describes the development and spread of antibiotic resistance in bacteria and discusses the difficulties in controlling this spread. The PowerPoint and accompanying worksheet have been designed to cover specification points 6.4 (i & ii) of the Edexcel A-level Biology B specification
President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. Moving forwards, 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of the development of resistance by evolution through natural selection. The main task of the lesson challenges the students to form a description to explain how this strain of bacteria developed resistance to methicillin, making use of the five key terms emphasised above. Moving forwards, there is a focus on the hospital as the common location for MRSA infections and students will recognise that this opportunistic pathogen can infect through open wounds to cause sepsis and potentially death. Figures from infections and deaths in hospitals in the US are used to increase the relevance and students will learn how a MRSA prevention program in VHA facilities includes screening of surgery patients to try to reduce its impact. The lesson concludes with a discussion about other methods that can be used by hospitals and general practitioners to reduce the spread of MRSA and to try to prevent the development of resistance in other strains.
This lesson outlines how bacteria become resistant to antiobiotics and discusses its consequences and the steps taken to reduce its impact. The PowerPoint and accompanying worksheet have been designed to cover specification points 10.2 (b & c) of the CIE A-level Biology specification
President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. Moving forwards, 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of the development of resistance by evolution through natural selection. The main task of the lesson challenges the students to form a description to explain how this strain of bacteria developed resistance to methicillin, making use of the five key terms emphasised above. Moving forwards, there is a focus on the hospital as the common location for MRSA infections and students will recognise that this opportunistic pathogen can infect through open wounds to cause sepsis and potentially death. Figures from infections and deaths in hospitals in the US are used to increase the relevance and students will learn how a MRSA prevention program in VHA facilities includes screening of surgery patients to try to reduce its impact. The lesson concludes with a discussion about other methods that can be used by hospitals and general practitioners to reduce the impact of MRSA and to try to prevent the development of resistance in other strains.
This lesson outlines how penicillin acts on bacteria and why antibiotics do not affect viruses. The PowerPoint and accompanying resources have been designed to cover point 10.2 (a) of the CIE A-level Biology specification and also introduces the concept of bactericidal and bacteriostatic antibiotics, as illustrated by penicillin and tetracycline.
The lesson begins with an engaging task, where the students have to identify the surnames of famous scientists from their descriptions to reveal the surname Fleming. This introduces Sir Alexander Fleming as the microbiologist who discovered penicillin in 1928. Time is taken to describe penicillin as a group of antibiotics that contain a beta-lactam ring in their molecular structure. Using this information and their knowledge of bacterial cell structure from topic 1, the students have to complete a passage describing how penicillin inhibits the formation of cross links in cell wall synthesis. A series of exam-style questions are then used to make links to the upcoming topic of antibiotic resistance.
The next part of the lesson focuses on the differences between bactericidal and bacteriostatic antibiotics and the students will learn that penicillin is bactericidal as the weakening of the cell wall leads to lysis and death. Tetracycline is used as the example of a bacteriostatic antibiotic and students will discover that it is the prevention of the binding of tRNA that inhibits protein synthesis and that this reduction and prevention of growth and reproduction is synonymous with these antimicrobial agents. Students are challenged on their knowledge of translation and will also be given time for a class discussion to understand that these antibiotics work in tandem the body’s immune system to overcome the pathogen
The final part of the lesson explains why antibiotics are ineffective against viruses.
This lesson describes the action of bactericidal and bacteriostatic antibiotics, as illustrated by penicillin and tetracycline. The engaging PowerPoint and accompanying resources have been designed to cover point 6.3 (i) of the Edexcel A-level Biology B specification but it has been specifically planned to make continual links to earlier lessons in topic 6 and to protein synthesis as covered in topic 1
The lesson begins by challenging the students to use their general biological knowledge and any available sources to identify the suffixes cidal and static. Students will learn that when the prefix is added, these form the full names of two types of antibiotics. Their understanding of terminology is tested further as they have to recognise that Polymyxin B is an example of a bactericidal antibiotic as its actions would result in the death of the bacterial cell. Time is then taken to describe the action of penicillin and students will learn how inhibitors and modified versions of this antibiotic are used to overcome those bacteria who have resistance. Tetracycline is used as the example of a bacteriostatic antibiotic and students will discover that its prevention of the binding of tRNA that inhibits protein synthesis and this reduction and stopping of growth and reproduction is synonymous with these drugs. Students are challenged on their knowledge of translation and will also be given time for a class discussion to understand that these antibiotics encourage the body’s immune system to overcome the pathogen in natural, active immunity.
The final part of the lesson uses a quick quiz competition and a series of exam-style questions to ensure that students can recognise these different types of antibiotics from descriptions.
The 4 lessons contained within this bundle are detailed and will engage the students whilst covering the following content in topic 11.1 of the CIE A-level Biology specification:
State that phagocytes have their origin in bone marrow and describe their mode of action
Describe the modes of action of B-lymphocytes and T-lymphocytes
Explain the meaning of the term immune response, making reference to the terms antigen, self and non-self
Explain the role of memory cells in long-term immunity
Explain, with reference to myasthenia gravis, that the immune system sometimes fails to distinguish between self and non-self
The PowerPoints and accompanying resources contain a wide range of tasks, which include exam-style questions, guided discussion periods and quiz competitions, and these have been designed to check on the students’ understanding of the current topic as well as previously-covered topics
This lesson describes self and non-self antigens and how a failure to distinguish between the two is the mechanism of autoimmune diseases. The PowerPoint and accompanying worksheets have been primarily designed to cover points 11.1 (d & f) of the CIE A-level Biology specification and describe examples of these diseases including myasthenia gravis, but this lesson can also be used to revise the content of the earlier topics as well as the previous lessons in topic 10 & 11 through the range of activities that are included
The first part of the lesson focuses on the antigens and explains how the failure of the immune system cells to recognise these molecules on the outside of a cell or organism elicits an immune response. Moving forwards, the students are challenged to recognise diseases from descriptions and then to use the first letters of their names to form the term, autoimmune. In doing so, the students will discover that rheumatoid arthritis, ulcerative colitis, type I diabetes mellitus, multiple sclerosis and myasthenia gravis are all examples of autoimmune diseases. The next part of the lesson focuses on the mechanism of these diseases where the immune system cells do not recognise the antigens (self-antigens) on the outside of the healthy cells, and therefore treats them as foreign antigens, resulting in the production of autoantibodies against proteins on these healthy cells and tissues. Key details of the autoimmune diseases stated above and lupus are described and links to previously covered topics as well as to future topics such as the pancreas and nervous system are made. The students will be challenged by the numerous exam-style questions, all of which have mark schemes embedded into the PowerPoint to allow for immediate assessment of progress.
This lesson describes why a disease would be deemed to be an autoimmune disease and describes the mechanisms involved in a few examples. The PowerPoint and accompanying worksheets have been primarily designed to cover point 4.1.1 (k) of the OCR A-level Biology A specification, but this lesson can also be used to revise the content of modules 2 and 3 and the previous lessons in 4.1.1 through the range of activities included
The lesson begins with a challenge, where the students have to recognise diseases from descriptions and use the first letters of their names to form the term, autoimmune. In doing so, the students will immediately learn that rheumatoid arthritis, ulcerative colitis, type I diabetes mellitus, multiple sclerosis and myasthenia gravis are all examples of autoimmune diseases. The next part of the lesson focuses on the mechanism of these diseases where the immune system cells do not recognise the antigens (self-antigens) on the outside of the healthy cells, and therefore treats them as foreign antigens, resulting in the production of autoantibodies against proteins on these healthy cells and tissues. Key details of the autoimmune diseases stated above and lupus are described and links to previously covered topics as well as to future topics such as the nervous system are made. The students will be challenged by numerous exam-style questions, all of which have mark schemes embedded into the PowerPoint to allow for immediate assessment of progress.
This lesson describes the means of transmission of animal and plant communicable pathogens, including direct and indirect transmission. The PowerPoint and accompanying worksheets have been primarily designed to cover point 4.1.1 (b) of the OCR A-level Biology A specification but intricate planning ensures that the students are constantly challenged on their recall of the content of the previous lesson, where the different types of pathogens that cause communicable diseases in plants and animals was covered.
The lesson contains a wide range of tasks which will engage the students whilst challenging them to think about the biological content. Relevant examples such as the UK government’s public message of “HANDS, FACE, SPACE” are used to explain how TB and HIV are directly transmitted through droplet infection or the exchange of bodily fluids. A series of exam-style questions challenge the students on their knowledge of the transmission of HIV and the mark scheme is embedded into the PowerPoint to allow them to assess their progress. Students will learn that although HIV is mainly a sexually transmitted infection, the sharing of needles by intravenous drug users and vertical transmission from a mother to foetus (or baby) are other mechanisms for the spread.
Moving forwards, the next part of the lesson focuses on the transmission of cholera and malaria in unsafe water and through a vector respectively. Time is taken to emphasise the meaning of a vector and student understanding is checked later in the lesson when discussing the spread of the fungus responsible for Dutch elm disease by the elm beetle. The effect of climate and social factors are also considered, and the outbreak of cholera in Yemen in 2016 is used to introduce a number of the social determinants that affect transmission.
The final part of the lesson describes the direct and indirect means of transmission of plant pathogens and biological examples are sourced to increase the relevance.