Using coloured blocks as models for chromosomes, Yan Wong shows how the 46 chromosomes in a dividing cell are assorted during meiosis into daughter cells, each with 23 chromosomes. Yan demonstrates crossing over between the chromosomes and illustrates how each of the daughters are genetically different. Yan also shows what goes wrong in conditions like Down’s syndrome: the chromosomes don’t separate properly during meiosis and one sex cell has one too many chromosomes.
Keywords: meiosis, Down syndrome
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