This fully-resourced lesson guides students through the construction of genetic crosses and pedigree diagrams for the inheritance of a single gene. The clear PowerPoint and accompanying resources have been designed to cover point 8.2 (ii) of the Edexcel A-level Biology B specification and includes the inheritance of multiple allele characteristics as well as those that demonstrate codominance. In order to minimise the likelihood of errors and misconceptions, step by step guides have been included throughout the lesson to support the students with the following: Writing parent genotypes Working out the different gametes that are made following meiosis Interpreting Punnett crosses to work out phenotypic ratios Students can often find pedigree trees the most difficult to interpret and to explain so exemplar answers are used as well as differentiated worksheets provided to support those students who need extra assistance.

This fully-resourced looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration effects the dissociation of adult oxyhaemoglobin. The PowerPoint and accompanying resources have been designed to cover point 8.1 (g) of the CIE International A-level Biology specification and continually ties in with the previous lesson on the role of haemoglobin in carrying oxygen. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual.

An engaging lesson presentation (30 slides) that looks at the different methods that are used to treat cardiovascular diseases. The lesson begins by looking at the surgical procedure of heart bypass before exploring the use of stents to widen a partially blocked artery. Links are made back to previous knowledge when discussing valves and students are challenged to explain why a faulty valve must be replaced. The rest of the lesson focusses on treating CVD with medicines such as statins and antiplatelets and students will learn the side-effects associated with these drugs. This lesson has been designed for GCSE students but is suitable for all ages

An engaging lesson presentation (61 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B2 (Organisation) of the AQA GCSE Biology specification (specification point 4.2) The topics that are tested within the lesson include: Principles of organisation The human digestive system The heart and blood vessels Blood Coronary heart disease The effect of lifestyle on some non-communicable diseases Plant organ systems Students will be engaged through the numerous activities including quiz rounds like “SPOT the SUBSTANCE" and “Where’s LENNY” whilst crucially being able to recognise those areas which need further attention

A resourced lesson which uses a concise lesson presentation (18 slides) and a differentiated diagram to guide students through the method of blood clotting. This lesson has been designed for students studying GCSE (14 - 16 year olds in the UK) and this is reflected in the appropriate detail where only the involvement of fibrin needs to be known. Students are shown how blood clotting is a cascade effect where one event leads on to the next.

An informative lesson presentation (20 slides) and associated worksheet that looks at how negative feedback loops act as a final control in homeostatic mechanisms. This is a topic which is poorly understood by students at both GCSE and even A-level, so whilst designing this lesson, the focus was on a few key points and applying it to a range of actual examples. Students will see how a negative feedback loop is used in the control of adrenaline release and temperature regulation and they will also be shown what would happen if this loop didn’t exist. Students are then challenged to apply their knowledge by putting the order of the regulation of metabolic rate into the correct order. The final part of the lesson briefly looks at how positive feedback loops also exist by using the example of the release of oxytocin during birth. This lesson has primarily been designed for GCSE students but is suitable for A-level Biology students too.

An engaging and detailed lesson presentation (53 slides) and associated worksheets that looks at the properties and functions of enzymes and explores how the rate of enzyme-controlled reactions changes with changes in conditions. The lesson begins by using a quick quiz competition to introduce the key terms of active site and substrate. Diagrams accompany the important descriptions so that students can visualise how enzymes are specific to a single substrate and will form enzyme-substrate complexes with only them. Emil Fischer’s lock and key hypothesis is briefly discussed so that the correlation between the hypothesis and key terms can be made. Students are shown how most enzymes or groups of enzymes can be named by remembering two rules and they will be tested on this through a second competition. At this point, a progress check is used to allow the students to assess their understanding and ability to bring the information together for enzyme function. The rest of the lesson looks at how changing the temperature and pH will affect the rate of an enzyme controlled reaction. Students will meet the graph shapes that accompany both of these factors and then are helped with the explanation of the trend which is normally poorly done in exam questions. This lesson has been designed for GCSE students.

This fully-resources lesson looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration affects the dissociation of oxyhaemoglobin. The PowerPoint has been designed to cover the second part of point 3.1.2 (j) of the OCR A-level Biology A specification and continually ties in with the previous lesson on the role of haemoglobin. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual. These questions are differentiated to allow students of differing abilities to access the work and to be challenged

This lesson focuses on the structure of RNA and specifically the similarities and differences between this nucleic acid and DNA so that students are prepared for the upcoming lessons on transcription and translation. The engaging and detailed PowerPoint and accompanying resource have been designed to cover part 1 of point 2.1.3 (g) of the OCR A-level Biology A specification which states that students should be able to describe the structure of molecules of messenger RNA, transfer RNA and ribosomal RNA. Students were introduced to nucleotides and the detailed structure of DNA in previous lessons, so this lesson is written to tie in with those and continuously challenge prior knowledge as well as understanding of the current topic. The lesson begins by reminding students that RNA is a member of the family of nucleic acids and therefore has a number of structural features that are commonly shared with DNA. A quiz round called “A FAMILY AFFAIR” is used to challenge their knowledge of DNA to recognise those features that are also found on RNA such as the chain of linked nucleotides, pentose sugars, nitrogenous bases and phosphodiester bonds. The next task pushes them to consider features that have not been mentioned and therefore are differences as they answer a structured exam-style question on how RNA differs from DNA. Students will learn that RNA is shorter than DNA and this leads into the final part of the lesson where mRNA and tRNA are introduced and again they are challenged to use the new information explain the difference in size. Brief details of transcription and then translation are provided so that students are prepared for the upcoming lessons on protein synthesis.

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Module 5.1.3 (Neuronal communication) of the OCR A-level Biology A specification. The sub-topics and specification points that are tested within the lesson include: The structure and function of sensory, motor and relay neurones The generation and transmission of nerve impulses in mammals The structure and roles of synapses in neurotransmission Students will be engaged through the numerous quiz rounds such as “Communicate the word” and “Only CONNECT” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

This is a highly-detailed revision resource which has been designed to be used over a number of lessons and allows teachers to dip in and out of the material as fits to the requirements of their classes and students. The resource consists of an engaging and detailed powerpoint (148 slides) and worksheets which have been differentiated to allow students of differing abilities to be challenged whilst accessing the work. The lesson consists of a wide range of activities which will engage and motivate the students and includes exam questions, quiz competitions and quick tasks and mathematical skills are challenged throughout. The lesson has been designed to cover as many of the sub-topics within topics 1, 2 and 3 of the OCR Gateway GCSE Biology A specification but the following sub-topics have been given particular attention: Topic B1: Cell-level systems Eukaryotic and prokaryotic cells Respiration Functions of the organelles of animal and plant cells Microscopy and calculating size Topic B2: Scaling up The functions of the components of blood Specialised cells Osmosis Mitosis and the cell cycle The heart and blood vessels Topic B3: Organism-level systems The nervous system The structures and functions of the eye IVF This revision resource can be used in the lead up to mocks or the actual GCSE exams and due to its size, it could be repeatably used to ensure that students develop a deep understanding of these topics.

This revision resource includes a range of activities that will act to engage and motivate the students whilst they assess their understanding of the Animal nutrition content (topic B6) of the CIE IGCSE Combined Science specification for examination in June and November 2020 and 2021. There are exam questions with explained answers as well as quick tasks and quiz competitions such as “Have you got the right BALANCE” where students are challenged to recognise whether a statement about the balanced diet is accurate or not. The lesson was designed to cover as much content as possible but the following topics have received particular attention: Mechanical digestion Chemical digestion by digestive enzymes Amylase and the break down of starch The adaptations of the small intestine to allow absorption The roles of the hydrochloric acid in gastric juice The break down of lipids in the small intestine The components of a balanced diet This resource includes a detailed and engaging PowerPoint (51 slides) and a worksheet which is differentiated two ways. Efforts have been made to make links to other topics such as enzymes (B4) so students can see the importance of being able to make connections in their answers

A fun and engaging lesson presentation (90 slides) and associated worksheets that uses exam questions, quick tasks and quiz competitions to allow students to assess their understanding of the topic of transport in plants, which is module 3.1.3 on the OCR A-Level Biology A specification. Competition rounds include “Keyword BINGO”, “Crack the Code” and “Make the Link” and students will enjoy being able to identify areas that require further attention. All exam questions have mark schemes. This lesson is designed for A-level students