This detailed lesson describes how gene expression can be changed by epigenetic modification, which is important in ensuring cell differentiation. The PowerPoint and accompanying resources describe DNA methylation, histone modification, and non-coding RNA as methods of modification and are part of the final lesson in a series of 3 lessons that cover the content in point 7.2 of the Edexcel A-level biology B specification (Factors affecting gene expression). HIV, atherosclerosis and cystic fibrosis are included in the lesson to demonstrate the application of this control of gene expression in real biological examples. Students are challenged throughout the lesson on their current understanding as well as their knowledge of previously covered topics which have links and the answers are embedded into the PowerPoint to allow them to assess their progress. The other lessons in this series are uploaded and are titled “transcription factors” and “RNA splicing”.

This revision lesson provides students with the opportunity to assess their understanding of the AQA A-level biology topic 6 content. The lesson includes a multiple-choice assessment of 20 questions which have been written to challenge the content of topic 6 (Organisms respond to changes in their internal and external environments) and a PowerPoint where the answers are revealed, along with explanations and key points related directly to the specification. The PowerPoint also includes other questions about topic 6 that aren’t directly challenged in the 20 questions, as well as prior knowledge checks to encourage the students to make links to content from topics 1 - 5. This resource has been designed to be used at the end of the teaching of topic 6 and/or in the build up to the final A-level assessments. Lessons challenging content from the other 7 specification topics are also uploaded.

This lesson has been designed to provide students with the opportunity to assess their understanding of topic 1 of the AQA A-level biology specification. Included in the lesson is an assessment consisting of 20 multiple choice questions and a PowerPoint containing the answers. The PowerPoint also contains explanations and key points related to the specification, as well as additional knowledge checks to challenge the content which isn’t directly covered by the 20 questions. There are also slides titled “Link to the future” where content is linked to upcoming lessons from topics 2 - 8. This lesson has been planned to be used at the end of topic 1, and/or in the build up to the final A-level assessments. Multiple-choice assessments for the other 7 topics are also uploaded.

This revision lesson provides students with the opportunity to assess their understanding of inheritance (topic 16). The lesson includes a multiple-choice assessment of 10 questions and a PowerPoint containing the answers, where each answer slide shows the exact specification code to enable students to note the areas which may require extra attention. The PowerPoint also contains additional questions to challenge content from topic 16 of the CIE A-level biology specification (2025 - 2027 update) that isn’t directly covered by the 10 questions, and prior knowledge checks to encourage students to make links to content from topics 1 - 15. This lesson has been designed to be used at the end of topic 16, and in the build up to mocks and the final A-level assessments.

This revision lesson provides students with the opportunity to assess their understanding of biological molecules (topic 2). The lesson includes a multiple-choice assessment of 10 questions and a PowerPoint containing the answers, where each answer slide shows the exact specification code to enable students to note the areas which may require extra attention. The PowerPoint also contains additional questions to challenge content from topic 2 of the CIE A-level biology specification (2025 - 2027 update) that isn’t directly covered by the 10 questions. This lesson has been designed to be used at the end of topic 2, and in the build up to mocks and the final A-level assessments.

This lesson describes how the movement of growth factors regulates growth in response to directional stimuli, focusing on gravitropism and phototropism. The PowerPoint and accompanying resources are part of the 1st lesson in a series of 3, which have been designed to cover point 6.1.1 (Survival and response) of the AQA A-level biology specification. The lesson begins with a prior knowledge check, where the students have to identify key terms encountered in topics 1 - 4, and use their 1st letters to form the term, stimuli. Students are reminded of the meaning of a stimulus, and this introduces the need for organisms to detect and respond to stimuli, to increase their chances of survival. This lesson focuses on these responses in flowering plants, and builds on any knowledge they may have gained at GCSE. They should have met auxins at this previous level, but will now be introduced to IAA, and will complete several tasks which check that they understand the key features of these chemicals, such as their location of production and method by which they move through the shoots and roots. The students are guided through the movement of IAA to the shaded side in a shoot during phototropism, and will learn how this uneven distribution leads to uneven growth. An exam-style question presents them with two further scenarios, where the tip of the shoot has been cut off or is covered, and the students need to describe and explain what will happen to the appearance of the shoot after a week. Moving forwards, the students will learn how the pumping of hydrogen ions into the cell wall and the activation of expansin proteins are involved in the cell elongation. The remainder of the lesson discusses the response to gravity and explains how shoots and roots respond differently. The lesson is full of understanding and prior knowledge checks and all answers are embedded into the PowerPoint. The other two lessons in this series of 3 covering 6.1.1 describe taxes and kineses and the protective effect of a simple reflex.

A fully resourced revision lesson which uses a range of exam questions (with explained answers), quick tasks and quiz competitions to enable the students to assess their understanding of the topics found within module 5.1.5 (Plant and animal responses) of the OCR A-level Biology A specification. The topics tested within this lesson include: Investigating tropisms The mammalian nervous system The brain Reflex actions Controlling heart rate Muscle Muscle contraction Student will enjoy the range of tasks and quiz rounds whilst crucially being able to recognise any areas which require further attention

A detailed lesson presentation which guides students through calculating the current, potential difference and resistance in series and parallel circuits. The lesson begins by challenging the students to recognise whether three displayed facts relate to series or parallel circuits. Students are then given a chance to remind themselves of the differences between the circuits in terms of these three physical factors. The rest of the lesson uses a step-by-step guide format to show the students how to work through a circuit calculation by combining their knowledge of the circuit with application of the V = IR equation. Progress checks have been written throughout the lesson so that students can constantly assess their understanding. This lesson has been designed for GCSE students

A fully-resourced lesson that looks at the details of the electrical topic of resistance that students need to know for GCSE. The lesson includes a lesson presentation (21 slides) and associated worksheets. The lesson begins by looking at the meaning of resistance and focuses on the connection between resistance and current. Moving forwards, net resistance in series and parallel circuits is introduced and explained.

A whole lesson on the topic of active transport which includes a concise lesson presentation (20 slides) and a set of questions that are used to check on the students’ understanding. This lesson is designed for GCSE students (14 - 16 year olds in the UK) but could be used with A-level students who are covering the topic of movement across cell membranes. The main focus of the lesson is to get students to understand that this is an active process which moves substances against the concentration gradient and therefore needs energy for this process. The final part of the lesson looks at the different types of questions that can accompany this topic and a step-by-step guide is used to answer a difficult longer answer question as a class.

A resourced lesson which looks at gas exchange at the alveoli and focuses on how these structures are adapted to carry out efficient gas exchange. The lesson includes an engaging lesson presentation (21 slides) and an associated worksheet. The lesson begins by revisiting the idea of the surface area to volume ratio of small organisms against larger organisms. This will remind students that due to the low surface area to volume ratio of a human, they need to have adaptations at the exchange surfaces to increase the surface area. Moving forwards, a range of competitions are used to introduce students to the numbers and key terms associated with the alveoli. Students will learn how the large number (700 million) of alveoli leads to a large surface area and how a permeable membrane is also essential. Time is written into the lesson to allow students to think about key features, such as the one cell thick lining, and relate this to the rate of diffusion. The lesson concludes with students completing a passage about how the respiratory and circulatory systems work together to maintain a steep concentration gradient between the alveoli and the capillaries. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

A concise, engaging lesson presentation (22 slides) which looks at the different responses of the body as a result of adrenaline release. In line with the actions of adrenaline, the lesson begins with a range of quiz competitions to introduce key terms and responses to the students. Once the students know that it causes both the breathing and heart rate to increase, they are challenged to complete a passage which brings this information together to explain how the increased respiration rate is related to the fight or flight tag line. Moving forwards, students will be introduced to the meaning of the term vasodilation and then asked to consider which organs will need extra blood flow during times of stress and conversely, which tissues can have blood directed away from them. The lesson finishes by looking at how a negative feedback loop is used as the final control to ensure that energy resources are not wasted during times when there is no stress.

A fully-resourced lesson which looks at the saturated hydrocarbons known as the alkanes and focuses on their structure and reactions. The lesson includes an engaging lesson presentation (38 slides) and an associated worksheet which is differentiated. The lesson begins with the introduction of the name of this group and then a step-by-step guide is used to show students how to draw the displayed formula. Once the first four have been drawn, students are shown how to calculate the general formula for the alkenes and then challenged to do the same for the alkanes. Moving forwards, students will meet the key term, saturated, and time is taken to ensure that the meaning of this word is understood in the context of this lesson. Once they have been introduced to bromine water, students are challenged to work out what will happen when this substance is added to an alkane and they have to explain their answer. The remainder of the lesson looks at the complete and incomplete combustion of the alkanes, focusing on the different products of these reactions and specifically the problems associated with carbon monoxide. There are regular progress checks throughout the lesson to allow the students to check on their understanding.

A resourced lesson which looks at three of the main components of blood and ensures that students can relate their features to their function. The lesson includes an engaging lesson presentation (31 slides) and an associated worksheet The lesson begins by challenging the students to recognise blood from a description of some of its contents. This will enable students to identify some of the substances like hormones and urea that are carried in the plasma. Moving forwards, the rest of the lesson takes a format where the students have to act as recruitment consultants. They have been given 3 job roles to fill and once they have decided on the right candidates for the job, they need to be able to explain why these have been chosen. Students will go study the red and white blood cells and platelets, focusing on how their different specialised features enable them to effectively carry out their respective functions. Students will be able to compare the cells in terms of size, number of nuclei and ultimately explain why they have their features. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been designed for GCSE students but is perfectly suitable to be used with KS3 students who are studying the circulatory system

A resourced lesson which looks at the key details of a titration to enable students to generate results which could be used in a titration calculation. The lesson includes an engaging lesson presentation (29 slides) and an associated worksheet. The lesson begins with a spot of fun as students are challenged to read the script of a scene from Friends to identify a neutralisation reaction. Students will learn that a method called a titration can use the results of an acid-base neutralisation to work out the concentration of an unknown. Students will learn the names of the equipment involved through a quiz competition and will then be shown how to set up a table to collect the results. Key terms such as titre, rough and end-point are explained. The lesson finishes with one further round of the competition called “Take the HOTSEAT” so that the knowledge of the key terminology from today’s lesson can be checked. The lesson has been designed with regular progress checks throughout so that students can check their understanding. This lesson has been designed for GCSE students.

A resourced lesson which looks at a number of examples of biological polymers. The lesson includes an engaging lesson presentation (40 slides) and a couple of worksheets to be used in the understanding check task. The starter activity challenges the students to use their Chemistry knowledge to come up with the abbreviation DNA. They will learn the key details of this polynucleotide and then time and focus is given to the nitrogenous bases and how they bond between the two strands. Moving forwards, students will be shown the next biological polymer that is a polypeptide. They are briefly shown how to draw a block diagram to represent the chain of amino acids. The final polymer are carbohydrates and students will learn how glycogen, starch and cellulose are formed from glucose monomers. Regular progress checks are written into the lesson at regular intervals to allow the students to check their understanding and ask questions. This lesson has been written for GCSE students

An engaging and practical based lesson presentation (24 slides) which challenges the students to carry out a range of practical tasks to learn the identification tests and positive results for the anions. The lesson begins by challenging the students to use their prior knowledge of chemical formulae to name two sets of ions. Students will be reminded of the definition of a cation so they can use this to write an accurate one for the anions. The rest of the lesson looks at the different tests and time is taken to explain the details behind each of them. Progress checks have been written into the lesson at regular intervals to allow the students to check their understanding. A set homework has also been included. This lesson has been written for GCSE students.

An informative and student-led lesson presentation (32 slides), accompanied by a reaction diagram and task worksheet, which together look at the key details of nuclear fission reactions. The lesson begins by introducing the students to the name of this reaction and to that of a neutron before they are challenged to recall the properties of this sub-atomic particle as this knowledge plays an important role in their understanding. Moving forwards, students will learn that two isotopes of uranium are involved and will discover and work out how one isotope is changed into the other. Diagrams accompany the theory throughout so that students can visualise how the reaction progresses. They are shown how to work out the two daughter nuclei that are produced in the reaction and how an equation can be written to represent nuclear fission. Progress checks have been written into the lesson at regular intervals so that students can constantly assess their understanding and any misconceptions can be immediately addressed. This lesson has been designed for GCSE students (14 - 16 year olds in the UK)

A practical based lesson presentation (26 slides) that investigates how increasing the temperature affects the rate of reaction and helps students to explain the trend in the results. Students can either carry out the reaction between sodium thiosulphate and hydrochloric acid or use the results which are provided. The equation to work out the rate of reaction is introduced to the students and they are challenged to plot the results on a line graph. A key term to be used in the explanation is introduced through a quick competition and then students are challenged to explain the trend