A fully resourced lesson which includes an informative lesson presentation (34 slides) and differentiated worksheets that show students how to convert between units so they are confident to carry out these conversions when required in Science questions. The conversions which are regularly seen at GCSE are covered as well as some more obscure ones which students have to be aware of. A number of quiz competitions are used throughout the lesson to maintain motivation and to allow the students to check their progress in an engaging way This lesson has been designed for GCSE students but is suitable for KS3

This revision lesson has been designed to challenge the students on their use of a range of mathematical skills that could be assessed on the AQA GCSE Combined Science papers. The mathematical element of the AQA GCSE Combined Science course has increased significantly since the specification change and therefore success in those questions which involve the use of maths can prove to be the difference between one grade and another or possibly even more. The engaging PowerPoint and accompanying resources contain a wide range of activities that include exam-style questions with displayed mark schemes and explanations so that students can assess their progress. Other activities include differentiated tasks, class discussion points and quick quiz competitions such as “YOU DO THE MATH” and “FILL THE VOID”. The following mathematical skills (in a scientific context) are covered in this lesson: The use of Avogadro’s constant Rearranging the formula of an equation Calculating the amount in moles using mass and relative formula mass Calculating the relative formula mass for formulae with brackets Using the Periodic Table to calculate the number of sub-atomic particles in atoms Changes to electrons in ions Balancing chemical symbol equations Converting between units Calculating concentration in grams per dm cubed and volumes of solutions Calculating size using the magnification equation Using the mean to estimate the population of a sessile species Calculating percentages to prove the importance of biodiversity Calculating percentage change Calculating the acceleration from a velocity-time graph Recalling and applying the Physics equations Understanding prefixes that determine size Leaving answers to significant figures and using standard form Helpful hints and step-by-step guides are used throughout the lesson to support the students and some of the worksheets are differentiated two ways to provide extra assistance. Due to the detail of this lesson, it is estimated that it will take in excess of 3 hours of GCSE teaching time to cover the tasks and for this reason it can be used over a number of lessons as well as during different times of the year for revision.

This fully-resourced lesson explores how new species arise when changes in the gene pool of two populations prevents members from interbreeding and producing fertile offspring. The engaging PowerPoint and accompanying resources have been designed to cover the fifth part of point 7.3 of the AQA A-level Biology specification which states that students should be able to describe allopatric and sympatric speciation. The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.

This fully-resourced lesson describes how antibodies are used in the enzyme-linked immunosorbent assay (ELISA) test. The PowerPoint and accompanying resources are part of the last lesson in a series of 7 which have been designed to cover the details within point 2.4 of the AQA A-level specification. As the last lesson in this sub-topic, prior knowledge checks are included throughout the lesson which challenge the students on their knowledge of antibodies, immunity and protein structure. The lesson begins by challenging the students to use the details of a poster to recognise that individuals who have recovered from COVID-19 could donate plasma and the antibodies be infused into newly infected individuals. They are then expected to answer a series of exam-style questions where they have to describe the structure of these specific antibodies, recognise this as artificial, passive immunity and describe the potential problems should the virus mutate and the shape of its antigens change. This leads into the introduction of the use of antibodies in other ways, namely the ELISA test. The methodology of this test has been divided into four key steps which students will consider one at a time and then answer further questions about key details such as the immobilisation of the antigen and the removal of proteins and antibodies that have not bound by the washing with the detergent after each step. The lesson focuses on the use of this test for medical diagnosis but other uses such as plant pathology and the detection of allergens is briefly introduced at the end of the lesson.

This lesson describes the differences between skeletal, smooth (involuntary) and cardiac muscle. The PowerPoint and accompanying resources form part of the 1st lesson in a series of 3 lessons which have been planned to cover the content of point 5.1.5 (l) (i) of the OCR A-level biology A specification. The other two lessons are “neuromuscular junctions” and “the sliding filament model of muscular contraction”. The lesson begins with a bit of fun by challenging the students to identify the prep room skeleton from a description and then to recognise that the reason the skeleton doesn’t have free movement or locomotion is because “he” lacks muscles. More specifically, it is the lack of skeletal muscles which prevents bones from moving and this leads into the introduction of this type of muscle tissue as being attached to bones. Time is taken to consider tendons, and more specifically the protein collagen, and students are challenged on their recall of this fibrous protein from module 2.1.2. This lesson contains numerous prior knowledge checks like this, to encourage them to identify the links between topics and modules. All answers to these prior knowledge and understanding checks are embedded into the PowerPoint to allow the students to assess their progress. The structure of skeletal muscle is covered in the 3rd lesson in this series, but this lesson does focus on the structural and functional differences between smooth and cardiac muscle. Students are introduced to intercalated discs and gap junctions in cardiac muscle and are challenged to explain how these features support the stages of the cardiac cycle. Earlier in this module, they covered the regulation of heart rate and a SPOT THE ERRORS task will challenge the detail of their knowledge of this control system. The remainder of the lesson focuses on smooth muscle, using examples in the gut wall, iris and arterial walls to increase relevance.

This is a fully-resourced REVISION lesson that challenges the students on their knowledge of the content found in TOPIC 4 (Biodiversity and Natural resources) of the Edexcel A-level Biology (Salters Nuffield) specification. The lesson contains an engaging PowerPoint (104 slides) and accompanying worksheets that use a range of exam questions, differentiated tasks and quiz competitions to motivate the students whilst they evaluate their knowledge of the different sub-topics. The lesson has been designed to cover as much of the topic 4 specification as possible, but the following sub-topics have been given particular attention: Three-domain classification The features of the kingdoms Evolutionary relationships Behavioural, anatomical and physiological adaptations Glycosidic bonds The structure and function of cellulose The ultrastructure of plant cells Calculating the index of diversity and the heterozygosity index Applying the Hardy-Weinberg principle to calculate allele frequencies This lesson is suitable for revision at the end of the topic, in the lead up to the mocks or in the lead up to the actual A-level exams as topic 4 is assessed on both Paper 1 and Paper 2.

This engaging lesson covers the biological classification of a species, phylogenetic classification and the use of the binomial naming system. The PowerPoint and accompanying resources have been designed to cover point 4.5 of the AQA A-level Biology specification which is titled species and taxonomy. The lesson begins by looking at the meaning of a population in Biology so that the term species can be introduced. A hinny, which is the hybrid offspring of a horse and a donkey, is used to explain how these two organisms must be members of different species because they are unable to produce fertile offspring. Although the art of courting might be lost on humans in the modern world, the marabou stork is used as an example to show how courtship behaviour is an essential precursor to successful mating in most organisms. Students are encouraged to discuss other examples of courtship behaviour, such as the release of pheromones and birdsong, so that their knowledge and understanding is broad. Moving forwards, students will learn that species is the lowest taxon in the modern-day classification hierarchy. A quiz runs throughout the lesson and this particular round will engage the students whilst they learn the names of the other 7 taxa and the horse and the donkey from the earlier example are used to complete the hierarchy. Students will understand that the binomial naming system was introduced by Carl Linnaeus to provide a universal name for each species and they will be challenged to apply their knowledge by completing a hierarchy for a modern-day human, by spotting the correct name for an unfamiliar organism and finally by suggesting advantages of this system. The final part of the lesson briefly looks at how advances in genome sequencing and the comparison of common biological molecules has allowed the relationships between organisms to be clarified. This is a detailed lesson and it is estimated that it will take around 2 hours of A-level teaching time to cover the content and therefore this specification point.

This lesson describes biodiversity and explains how it can be calculated within a species, a habitat and how it can be compared between habitats. The detailed PowerPoint and accompanying resources have been designed to cover points 4.16, 4.17 & 4.18 in unit 2 of the Edexcel International A-level Biology specification and the meaning of endemism is also explained. A quiz competition called BIOLOGICAL TERMINOLOGY SNAP runs over the course of the lesson and this will engage the students whilst challenging them to recognise key terms from their definitions. This quiz will introduce species, population, biodiversity, endemic, heterozygote and natural selection and each of these terms is put into context once introduced. Once biodiversity has been revealed, the students will learn that they are expected to be able to measure biodiversity within a habitat, within a species and within different habitats so that they can be compared. The rest of the lesson uses step by step guides, discussion points and selected tasks to demonstrate how to determine species richness, the heterozygosity index and an index of diversity. Students are challenged with a range of exam-style questions where they have to apply their knowledge and all mark schemes are displayed and clearly explained within the PowerPoint to allow students to assess their understanding and address any misconceptions if they arise.

This lesson explains how labelled DNA probes can be used to screen patients for heritable conditions, their responses to drugs and to identify health risks. The PowerPoint and accompanying resources have been designed to cover the content of point 8.4.2 of the AQA A-level biology specification. The lesson begins by introducing the BRCA genes, and the students will learn how faulty alleles of these two genes can increase an individual’s risk of developing breast cancer. Therefore, there is a need to be able to locate specific alleles like these, and this function is performed by DNA probes. The students are challenged to use the function of the probes to predict their structure and will understand that they are short lengths of single stranded DNA that have a base sequence complementary to the base sequence of part of the target allele. As shown in the cover image, a quick quiz round is used to introduce hybridisation as key term, to ensure that students recognise that the probe will bind if the complementary base sequence is encountered. Moving forwards, a DNA microarray is introduced to show that it’s possible to screen for multiple genes. The remainder of the lesson considers how the DNA probes are used to screen for heritable conditions and drug responses, and real-life examples are used to increase relevance. Prior knowledge checks are embedded throughout the lesson to encourage the students to make links to content from earlier topics including inheritance and genetic drift.

This fully-resourced lesson explores the inheritance of sex-linked diseases in humans and then challenges the students to apply their knowledge to examples in other animals. The detailed PowerPoint and associated differentiated resources have been designed to cover the part of point 7.1 of the AQA A-level specification which states that students should be able to use fully-labelled genetic diagrams to predict the results of crosses involving sex-linkage. Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final tasks of the lesson challenge the students to carry out a dihybrid cross that involves a sex-linked disease and an autosomal disease before applying their knowledge to a question about chickens and how the rate of feather production in chicks can be used to determine gender. All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual markschemes to allow them to assess their progress and address any misconceptions

This lesson describes the pathway by which the translation of mRNA into proteins can be prevented by siRNA and miRNA molecules. The engaging and detailed PowerPoint and accompanying resources are part of the final lesson in a series of 4 lessons that cover the detail of point 8.2.2 of the AQA A-level biology specification. The lesson begins with an exisiting knowledge check, as the students are challenged to recognise the processes of DNA methylation and histone acetylation, before RNA interference is introduced as another way by which gene expression is controlled in eukaryotes. Moving forwards, a quick quiz round introduces small interfering RNA (siRNA) and students will learn how this double-stranded, non-coding RNA is normally just 21 base pairs long. A step by step guide then describes the action of siRNA in preventing translation, through the cutting of the target mRNA into fragments which are then degraded. Time is taken to consider the possible application of siRNA molecules in the treatment of HIV and then cystic fibrosis, and the latter involves a series of exam-style questions which challenge the students on their understanding of this topic as well as the recall of content from the other 7 AQA topics. The remainder of the lesson focuses on microRNA (miRNA) and students will understand how this molecule is produced and how its action differs to that of siRNA in mammalian cells.

This highly detailed, fully-resourced lesson has been designed to cover the content of specification point 5.1.4 (d) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the regulation of blood glucose concentration. There is focus on the negative feedback mechanisms that release insulin or glucagon and the role of the liver. It challenges the students recall of the control of insulin release from the beta cells which was taught in an earlier lesson. A wide range of activities will maintain motivation and engagement whilst the content is covered in detail to enable the students to explain how the receptors in the pancreas detect the concentration change and how the hormones attaching to receptor sites on the liver triggers a series of events in this effector organ. This is a topic which has a huge amount of difficult terminology so time is taken to look at all of the key words, especially those which begin with the letter G so students are able to use them accurately in the correct context. The action of adrenaline is also considered and linked to the breakdown of glycogen to glucose during glycogenolysis. This lesson has been written for students studying on the OCR A-level Biology A course and ties in with the lesson on the differences between type I and II diabetes mellitus as well as the human endocrine system

An engaging lesson presentation (16 slides) which looks at the surface area to volume ratio and ensures that students can explain why this factor is so important to the organisation of living organisms. This is a topic which is generally poorly misunderstood by students and therefore time has been taken to design an engaging lesson which highlights the key points in order to encourage greater understanding. The lesson begins by showing students the dimensions of a cube and two answers and challenges them to work out what the questions were that produced these answers. Students are shown how to calculate the surface area and the volume of an object before it is explained how this can then be turned into a ratio. Time is taken at this point to ensure that students can apply this new-found knowledge as they have to work out which of the three organisms in the “SA: V OLYMPICS” would stand aloft the podium. Students are given the opportunity to draw conclusions from this task so that they can recognise that the larger the organism, the lower the surface area to volume ratio. The lesson finishes by explaining how larger organisms, like humans, have adapted in order to increase the surface area at important exchange surfaces in their bodies. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been written for GCSE students but is perfectly suitable for A-level students who want to look at this topic from a basic level