This lesson describes how the nervous system allows effectors to respond to stimuli and also describes hormonal control in animals. The PowerPoint and accompanying resources have been primarily designed to cover points 8.2 & 8.13 of the Edexcel International A-level Biology specification but it can also be used as a revision lesson as there are numerous prior knowledge checks of muscle contraction, protein structure and the control of gene expression. The lesson begins by challenging the students to recall that a control system contains sensory receptors, a coordination centre and effectors. Sensory receptors are covered in detail later in the topic when some key examples are considered as well as those in the retina, but time is taken now to describe how these structures act like transducers, converting one form of energy into electrical energy and the Pacinian corpuscle is used as an example. The students will learn that the communication between the receptors and the coordination centre and the effectors is by cell signalling and that the effectors can be muscles which contract or glands that release chemicals. The next part of the lesson looks at the differing responses from the nervous and hormonal systems and discusses how this can be governed by the need for a rapid response or more of a long term effect. In terms of nervous control, the students are challenged on their recall of the sliding filament theory of muscle contraction as covered in topic 7. Moving forwards, the students will learn that hormones can be either peptide or steroid hormones and their action at a target cell differs based on their form. Students are tested on their knowledge of protein structure by a series of exam-style questions on insulin and glucagon. They are reminded that steroid hormones can pass directly through the cell membrane and their knowledge of the control of gene expression by transcription factors is tested through a task involving oestrogen and the ER receptor. The lesson concludes by reminding students that the control of heart rate, as covered in topic 7, is a coordinated response that involves both nervous and hormonal control.

This lesson describes the role of the posterior pituitary gland and ADH in the homeostatic balance of blood water potential. The PowerPoint and accompanying resources have been designed to cover specification points (f & g) in topic 7 of A2 unit 3 of the WJEC A-level Biology specification. Students learnt about the principles of homeostasis and negative feedback in an earlier lesson in this topic, so this lesson acts to build on that knowledge and challenges them to apply their knowledge. A wide range of activities have been included in the lesson to maintain motivation and engagement whilst the understanding and prior knowledge checks will allow the students to assess their progress as well as challenge themselves to make links to other Biology topics. The lesson begins with a discussion about how the percentage of water in urine can and will change depending on the blood water potential. Students will quickly be introduced to osmoregulation and they will learn that the osmoreceptors and the osmoregulatory centre are found in the hypothalamus. A considerable amount of time is taken to study the cell signalling between the hypothalamus and the posterior pituitary gland by looking at the specialised neurones (neurosecretory cells). Links are made to the topics of neurones, nerve impulses and synapses and the students are challenged to recall the cell body, axon and vesicles. The main section of the lesson forms a detailed description of the body’s detection and response to a low blood water potential. The students are guided through this section as they are given 2 or 3 options for each stage and they have to use their knowledge to select the correct statement. The final task asks the students to write a detailed description for the opposite stimulus

This lesson describes how the structures of the xylem vessels, sieve tube elements and companion cells relates to their functions. The PowerPoint and accompanying resources have been designed to cover points (m & q) in topic 3 of AS unit 2 of the WJEC A-level Biology specification. Please note that this lesson does not include light and electron microscope pictures, so teachers will have to source and add these in themselves. The lessons begins by challenging the students to identify the substances that a plant needs for the cellular reactions, where they are absorbed and where these reactions occur in a plant. The aim of this task is to get the students to recognise that water and mineral ions are absorbed in the roots and needed in the leaves whilst the products of photosynthesis are in the leaves and need to be used all over the plant. Students will be reminded that the xylem and phloem are part of the vascular system responsible for transporting these substances and then the rest of the lesson focuses on linking structure to function. A range of tasks which include discussion points, exam-style questions and quick quiz rounds are used to describe how lignification results in the xylem as a hollow tube of xylem cells to allow water to move as a complete column. They will also learn that the narrow diameter of this vessel allows capillary action to move water molecules up the sides of the vessel. The same process is used to enable students to understand how the structures of the companion cells allows assimilates to be loaded before being moved to the sieve tube elements through the plasmodesmata.

This fully-resourced lesson guides students through the principles of monohybrid inheritance, focusing on the importance of alleles. The PowerPoint and accompanying resources have been designed to cover points (a & b) in topic 3 of A2 unit 4 of the WJEC A-level Biology specification and includes the inheritance of alleles that demonstrate codominance. In order to minimise the likelihood of errors and misconceptions, step by step guides have been included throughout the lesson to support the students with the following: Writing parent genotypes Working out the different gametes that are made following meiosis Interpreting Punnett crosses to work out phenotypic ratios Students can often find pedigree trees the most difficult to interpret and to explain so exemplar answers are used as well as differentiated worksheets provided to support those students who need extra assistance

This lesson describes the key events of the eukaryotic cell cycle and specifically focuses on those that occur in interphase. The PowerPoint and accompanying resources have been designed to cover point (a) in topic 6 of AS unit 1 of the WJEC A-level Biology specification and also introduces the stages of mitosis and cytokinesis to prepare students for the upcoming lesson on the significance of this type of cell division. The students were introduced to the cell cycle at GCSE so this lesson has been planned to build on that knowledge and to emphasise that the M phase which includes mitosis (nuclear division) only occupies a small part of the cycle. The students will learn that interphase is the main stage and that this is split into three phases, G1, S and G2. A range of tasks which include exam-style questions, guided discussion points and quick quiz competitions are used to introduce key terms and values and to describe the main processes that occur in a very specific order. Extra time is taken to ensure that key terminology is included and understood, such as sister chromatid and centromere, and this focus helps to show how it is possible for genetically identical daughter cells to be formed at the end of the cycle.

This lesson describes the vascular system of mammals as a double circulatory system to allow comparisons with those in earthworms, insects and fish. The PowerPoint and accompanying resources have been designed to cover the final content of specification point (a) in topic 3 (Adaptations for transport) of AS unit 2 in the WJEC A-level Biology specification and there is a primary focus on the differences in pressure between the pulmonary and systemic circulation. The lesson begins with a focus on the meaning of a double circulatory system and checks that students are clear in the understanding that the blood passes through the heart twice per cycle of the body. Beginning with the pulmonary circulation, students will recall that the pulmonary artery carries the blood from the right ventricle to the lungs. An opportunity is taken at this point to check on their knowledge of inhalation and the respiratory system as well as the gas exchange between the alveoli and the capillary bed. A quick quiz is used to introduce arterioles and students will learn that these blood vessels play a crucial role in the changes in blood pressure that prevent the capillaries from damage. When looking at the systemic circulation, time is taken to look at the coronary arteries and renal artery as students have to be aware of these vessels in addition to the ones associated with the heart. In the final part of the lesson, students are challenged to explain how the structure of the heart generates a higher pressure in the systemic circulation and then to explain why the differing pressures are necessary.

This lesson describes the meaning of the terms stroke volume and heart rate and explains how to use them to calculate the cardiac output. The PowerPoint and accompanying resources have been designed to cover the content of specification point 8.12 of the Edexcel GCSE Biology & Combined Science specifications. The lesson begins by challenging the students to use their knowledge of the structure of the heart chambers to identify the one which has the most muscular wall. Their discussions should lead to the left ventricle and following the introduction of the key term stroke volume using a quick quiz competition, they will learn that this factor is the volume of blood pumped out of the left ventricle each heart beat. Another competition introduces the normative values for stroke volume and the resting heart rate and then the students are challenged to use the provided equation to calculate the cardiac output and to write a definition for this factor using their current understanding. The remainder of the lesson considers how these three factors change during exercise and they are challenged to apply their understanding through a series of exam questions. This worksheet is differentiated two ways and the mark scheme is embedded into the PowerPoint to allow the students to assess their progress.

This lesson describes the role of meiotic cell division, including a detailed explanation of how 4 genetically unidentical daughter cells are formed. The PowerPoint and accompanying resources have been designed to cover point 3.3 of the Edexcel GCSE Biology and Combined Science specifications. The students covered the mitotic cell cycle in topic 2 and their knowledge of this type of cell division is utilised throughout the lesson to help with the understanding of this cycle. The lesson begins by challenging the students to recall the meaning of diploid and they will learn that the parent cell at the start of the meiotic cell cycle is a diploid cell. Time is taken to remind them of the events of interphase and then the lessons focuses on the 2 sets of division in meiosis which produces four haploid daughter cells. The identity of these cells as gametes is emphasised. The final part of the lesson uses a series of exam questions to challenge the students on their understanding of the cycle and the mark schemes are embedded into the PowerPoint to allow the students to assess their progress.

This lesson uses step by step guides to describe how to calculate the surface area to volume ratio. The PowerPoint and accompanying resources are part of the first lesson in a series of 2 lessons which have been designed to cover the detail of points 8.2 and 8.3 of the Edexcel GCSE Biology & Combined Science specifications. The calculation of the SA/V ratio can be an area of the course that students find difficult so this lesson breaks the calculation into parts to guide them through each step. The students are shown how to calculate the surface area, then the volume and then how to express the answer of the division calculation as a ratio against 1. After each step, the students are given the opportunity to apply their understanding and all questions have mark schemes with full workings embedded into the PowerPoint to allow the students to self-assess. Students also tend to struggle to see the relevance to Biology so the remainder of the lesson involves the calculation of the ratio for the alveoli in the human body. Students will discover that the surface area to volume ratio is significantly increased in these gas exchange surfaces which leads into the upcoming lesson on the adaptations of the alveoli to overcome the overall low ratio in larger organisms.

This lesson explains the meaning of 11 key terms associated with the genetic inheritance topic and challenges the students to use them in context. The PowerPoint and accompanying resources have been designed to cover point 6.1.6 of the AQA GCSE Biology specification and include explanations of genome, chromosome, gene, allele, genotype, homozygous, heterozygous, phenotype, dominant, recessive and gamete. The key term, genome, was met earlier in topic 6 so the lesson begins with a knowledge retrieval with the definition for this term. As the genome is the entire DNA of an organism, the next task challenges the students to identify three errors in a passage about DNA. This leads into discussions about chromosomes and genes and time is taken to explain that homologous chromosomes have the same genes at the exact same gene loci. The students will learn that alternative forms of the gene (alleles) can be found at these loci and that these structures explain the differences in inherited characteristics. Moving forwards, the main section of the lesson describes the link between the dominant and recessive alleles, homozygous and heterozygous genotypes, and the physical expression as the phenotype. The final key term is gamete, and the students are challenged to recognise a definition for this term using their knowledge of meiosis. Two progress and understanding checks complete the lesson and check on the students’ ability to recognise and write definitions for these 11 terms and to use them accurately in a written description

This lesson describes how to investigate the distribution and abundance of organisms and how to estimate the numbers of a species in a habitat. The PowerPoint and accompanying resources are part of the first lesson in a series of two lessons which have been designed to cover the details of point B6.1a of the OCR GCSE Biology specification. This first lesson focuses on the use of a quadrat to estimate population size as well as belt transects to consider distribution. Step by step guides are used throughout the lesson to model the workings required in the calculations. This includes the use of a 1 metre squared quadrat as well as other areas. Once a method has been modelled, the students are challenged with a series of exam questions and mark schemes are embedded into the PowerPoint to allow the students to self-assess.

This engaging and detailed lesson presentation (43 slides) uses a step by step guide to take students through the important scientific skill of drawing graphs to represent data and address all the misconceptions and misunderstandings that often accompany this topic. The lesson begins by explaining to the students how to decide whether data should be represented on a line graph or a bar chart and a competition called "To BAR or not to BAR" is used to allow them to check their understanding while maintaining motivation. Moving forwards, students are shown a 6 step guide to drawing a line graph. Included along the way are graphs that are wrong and explanations as to why so that students can see what to avoid. There are continuous progress checks and a homework is also included as part of the lesson. This lesson is written for students of all ages who are studying Science.

This fully-resourced lesson looks at the process and site of the Krebs cycle and explains the importance of decarboxylation, dehydrogenation, the reduction of NAD and FAD and substrate level phosphorylation. The engaging and detailed PowerPoint and accompanying resource have both been designed to cover point 5.2.2 (e) of the OCR A-level Biology A specification and includes the formation of citrate from the acetyl group of acetyl CoA and oxaloacetate and the regeneration of this four carbon molecule. The lesson begins with a version of the Impossible game where students have to spot the connection between 8 of the 9 terms and will ultimately learn that this next stage is called the Krebs cycle. The main part of the lesson challenges the students to use descriptions of the main steps of the cycle to continue their diagram of the oxidation-reduction reactions. Students are continually exposed to key terminology such as decarboxylation and dehydrogenation and they will learn where carbon dioxide is lost and reduced NAD and FAD are generated. They will also recognise that ATP is synthesised by substrate level phosphorylation. The final task challenges them to apply their knowledge of the cycle to work out the numbers of the different products and to calculate the number of ATP that must be produced in the next stage if the theoretical yield of 32ATP is to be achieved. This lesson has been designed to tie in with the other uploaded lessons on glycolysis, anaerobic respiration, the Link reaction, oxidative phosphorylation and respiratory substrates

This fully-resourced lesson looks at the process and site of glycolysis and explains how the phosphorylation of glucose and the production and oxidation of triose phosphate results in 2 molecules of pyruvate. The engaging PowerPoint and accompanying differentiated resources have been designed to cover point 5.2.2 © of the OCR A-level Biology A specification. The lesson begins with the introduction of the name of the stage and then explains how the phosphorylation, splitting and oxidation are the three main stages that need to be known for this specification. Time is taken to explain the key details of each of these stages and key points such as the use of ATP in phosphorylation are explained so that students can understand how this affects the net yield. A quick quiz competition is used to introduce NAD and the students will learn that the reduction of this coenzyme, which is followed by the transport of the protons and electrons to the cristae for the electron transport chain, is critical for the overall production of ATP. Understanding checks, in a range of forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed. This lesson has been written to tie in with the other uploaded lessons on the Link reaction, Krebs cycle, oxidative phosphorylation and anaerobic respiration

An engaging lesson presentation (30 slides) that looks at the different methods that are used to treat cardiovascular diseases. The lesson begins by looking at the surgical procedure of heart bypass before exploring the use of stents to widen a partially blocked artery. Links are made back to previous knowledge when discussing valves and students are challenged to explain why a faulty valve must be replaced. The rest of the lesson focusses on treating CVD with medicines such as statins and antiplatelets and students will learn the side-effects associated with these drugs. This lesson has been designed for GCSE students but is suitable for all ages

This detailed lesson describes the principles of DNA sequencing and has been designed to cover the first part of point 6.1.3 (a) of the OCR A-level Biology A specification. Fred Sanger’s chain termination method is used as the example to guide the students through the details of each step. The lesson begins with a focus on the common ingredients of the process such as DNA polymerase, DNA nucleotides and primers. Links are made to module 2.1.3 where nucleic acids were initially met through a series of prior knowledge check questions. Time is then taken to explain why these short lengths of synthesised nucleotides are necessary and this will support students when primers are met in the PCR and genetic engineering. Moving forwards, students will recognise how the modification to the nucleotide means that the chain terminates once a modified nucleotide is added into the sequence and that these have been radioactively labelled. Gel electrophoresis is introduced and an outline of the process given to provide knowledge to build on when this is encountered later in the module. A series of exam-style questions allow students to assess their understanding of this potentially difficult topic before students are encouraged to consider the limitations of the method so they are prepared to meet the new methods in upcoming lessons. A number of quiz competitions run throughout the lesson to maintain engagement and to introduce terms and values in a memorable way

This is a fully-resourced lesson that covers the details of specification point 5.1.2 (e) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the effects of kidney failure and its potential treatments. This lesson consists of an engaging PowerPoint (55 slides) and associated differentiated worksheets that look at the diagnosis of a number of different kidney-related conditions and the potential treatments for kidney failure. This lesson is designed to get the students to take on the numerous roles of a doctor who works in the renal ward which include testing, diagnosis and treatment. Having obtained measurements by GFR and results by taking urine samples, hey are challenged to use their knowledge of the function of the kidney to study urine samples (and the accompanying GP’s notes) to diagnose one of four conditions. They then have to write a letter to the patient to explain how they made this diagnosis, again focusing on their knowledge of the structure and functions of the Bowman’s capsule and PCT. The rest of the lesson focuses on haemodialysis, peritoneal dialysis and kidney transplant. There are regular progress checks throughout the lesson so that students can assess their understanding and there are a number of homework activities included in the lesson. This lesson is designed for A-level students who are studying the OCR A-level Biology specification and ties in nicely with the other uploaded lessons on this organ which include the structure and function of the nephron, ultrafiltration, selective reabsorption and osmoregulation.

An engaging lesson presentation (43 slides) that uses exam questions, quick tasks and competitions to enable students to assess their understanding of the topics within module 6.1.3 of the OCR A-Level Biology A specification. All of the exam questions have displayed mark schemes and explanations so that students can recognise any errors or misconceptions. Competition rounds included in this lesson are "From numbers 2 letters" and "Is this SEQUENCED correctly".

A fully resourced lesson which uses a combination of exam questions, quick tasks and quiz competitions to enable students to assess their understanding of the topics found within module 5.2 (Excretion as an example of homeostatic control) of the OCR A-level Biology A specification. The following topics are tested within the lesson: Excretion The structure of the liver Liver function Kidney structure Kidney function Osmoregulation Kidney failure Students will be engaged through the various activities whilst crucially being able to recognise those areas which need further attention.