This lesson describes how the cells of multicellular organisms are organised into tissues, tissues into organs and organs into systems. The detailed and engaging PowerPoint and accompanying resources have been designed to cover point 3.13 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification and focuses on the levels of organisation in humans and plants The lesson begins by using the process of haematopoiesis from haematopoietic stem cells to demonstrate how the red blood cell and neutrophil differ significantly in structure despite arising from the same cell along the same cell lineage. A series of exam-style questions will not only challenge their knowledge of structure but also their ability to apply this knowledge to unfamiliar situations. These differences in cell structure is further exemplified by the epithelial cells of the respiratory tract and students are challenged to remember how the shape and arrangement of these cells differ in the trachea and alveoli in relation to their function. The link between specialised cells and tissues is made at this point of the lesson so students are reminded that a tissue is a group of cells that work together to perform a specific function or set of functions. Moving forwards, a quick quiz competition will challenge the students to recognise the liver, kidney, spinal cord and pancreas from a brief functional description and this leads into a series of questions that links back to topics 1 and 2 and earlier in topic 3 where blood clotting, proteins, osmosis, organelles, methods of transport, carbohydrates and enzymes were originally covered. These prior knowledge checks are found throughout the lesson, along with current understanding checks, and all of the mark schemes are embedded into the PowerPoint to allow students to assess their progress. In terms of organ systems, a quick task challenges them to recognise 8 of the 11 that are found in humans from descriptions and this leaves them to identify the gaseous exchange, digestive and reproductive systems as the remaining 3. This leads into a section about cystic fibrosis as this genetic disorder impairs the functioning of these systems. The remainder of the lesson focuses on specialised plant cells and the differing shapes and features of the palisade and spongy cells in the mesophyll layer and the guard cells are covered at length and in detail. The cells found in the xylem and phloem tissue are also discussed.

This lesson describes how the expression of a gene mutation impairs the functioning of the gaseous and digestive systems in people with cystic fibrosis. The detailed PowerPoint and accompanying worksheets have primarily been designed to cover points 2.12 (ii) and 2.14 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification but also challenges the students on their knowledge of previously-covered topics including monohybrid inheritance, protein synthesis, genetic code and blood clotting as well as making links to the upcoming topics of loci, organisation of multicellular organisms and post-transcriptional changes. The main focus of the lesson is the CFTR gene and the functions of the ion channel that is synthesised when this gene is expressed. As well as explaining that this channel allows chloride ions to flow across the apical membrane of the epithelial cells, time is taken to emphasise the importance of its inhibition on the ENaC, which prevents the flow of sodium ions back into the cells. A step by step guide is then used to describe the sequence of events that result in mucus which is motile and can be moved by the wafting action of the cilia in healthy individuals. This leads into the section of the lesson which considers the inheritance of cystic fibrosis in an autosomal recessive manner and then focuses on the change in the primary structure of the channel which results from one of over 1500 different gene mutations. Again, the students are guided through the events that lead to the depletion of the apical surface liquid and the cilia being unable to move the viscous mucus. Although the majority of the lesson is described with reference to the gaseous exchange system, the impaired functioning of the digestive system in terms of the blockage of the pancreas and liver secretions is considered and discussed and the students are challenged on their understanding through a range of exam-style questions. All of the questions included in the lesson have mark schemes which are embedded into the PowerPoint and this allows the students to assess their progress. Due to the detailed content of this lesson, it is estimated that it will take in excess of 3 hours of allocated A-level teaching time to cover

This lesson describes how the expression of a gene mutation impairs the functioning of the organ systems in people with cystic fibrosis. The detailed PowerPoint and accompanying worksheets have primarily been designed to cover point 2.16 in AS unit 1 of the Edexcel International A-level Biology specification but also challenge the students on their knowledge of previously-covered topics such as inheritance, protein synthesis and the genetic code as well as making links to the upcoming topics of loci and post-transcriptional changes. The main focus of the lesson is the CFTR gene and the functions of the ion channel that is synthesised when this gene is expressed. As well as explaining that this channel allows chloride ions to flow across the apical membrane of the epithelial cells, time is taken to emphasise the importance of its inhibition on the ENaC, which prevents the flow of sodium ions back into the cells. A step by step guide is then used to describe the sequence of events that result in mucus which is motile and can be moved by the wafting action of the cilia in healthy individuals. This leads into the section of the lesson which considers the inheritance of cystic fibrosis in an autosomal recessive manner and then focuses on the change in the primary structure of the channel which results from one of over 1500 different gene mutations. Again, the students are guided through the events that lead to the depletion of the apical surface liquid and the cilia being unable to move the viscous mucus. Although the majority of the lesson is described with reference to the gaseous exchange system, the impaired functioning of the digestive system in terms of the blockage of the pancreas and liver secretions is considered and discussed and the students are challenged on their understanding through a range of exam-style questions. All of the questions included in the lesson have mark schemes which are embedded into the PowerPoint and this allows the students to assess their progress. Due to the detailed content of this lesson, it is estimated that it will take in excess of 3 hours of allocated A-level teaching time to cover

This lesson describes the mechanisms of ventilation and gas exchange in insects. The PowerPoint and accompanying worksheets are the part of the second lesson in a series of 2 lessons which have been designed to cover the details that are set out in point 3.1.1 (f) of the OCR A-level Biology A specification. The first lesson in this series describes ventilation and gas exchange in bony fish In the previous lesson, the students were introduced to the different circulatory systems of mammals and bony fish and this knowledge is checked upon at the start of this lesson. This is relevant because the open circulatory system of an insect explains how oxygen is not transported in the blood but instead is absorbed from the body fluid that bathes the tissues. The next part of the lesson describes the structure of the spiracles, tracheae and tracheoles in the tracheal system and explains how this system is responsible for the delivery of oxygen to the open end of the tracheole for gas exchange with this fluid. As the tracheae are supported by chitin, which is similar in structure and function to cellulose and keratin respectively, a series of exam-style questions are used to challenge the students on their knowledge of those polymers from module 2.1.2 (biological molecules). As always, the mark scheme is embedded in the powerpoint so students can assess their understanding and progress. The final part of the lesson describes how squeezing of the tracheoles by the flight muscles and the changes in the volume of the thorax as a result of the movement of the wings are similar to mechanisms observed in mammals.

This lesson describes how the surfaces in insects, fish and mammals are adapted for gas exchange. The PowerPoint and accompanying worksheets have been designed to cover the detail of point 4.3 (i) of the Edexcel A-level Biology B specification. The lesson has been intricately planned to challenge the students on their understanding of the surface area to volume ratio (as covered in topic 4.1) and to make direct links to upcoming lessons on the transport systems in humans. The lesson begins by explaining that single-celled organisms are able to diffuse oxygen and carbon dioxide across their body surface but that as organisms increase in size and their SA/V ratio decreases, they need adaptations at their gas exchange surfaces to be able to obtain the oxygen to meet their metabolic demands. This leads into the next part of the lesson which describes the roles of the following structures in insects and bony fish: spiracles, tracheae, tracheoles and tracheole fluid operculum, gill arch, gill filaments and lamellae The next task challenges the students to use their knowledge of topics 1, 2 and 3 to come up with the letters that form the key term, countercurrent flow. This is a key element of the lesson and tends to be a principle that is poorly understood, so extra time is taken to explain the importance of this mechanism. Students are shown two diagrams, where one contains a countercurrent system and the other has the two fluids flowing in the same direction, and this is designed to support them in recognising that this type of system ensures that the concentration of oxygen is always higher in the oxygenated water than in the blood in the lamellae. As the alveoli as a structure of gas exchange was introduced at GCSE, this final part of the lesson has been written to challenge the recall of that knowledge and to build on it. The main focus is the type of epithelium found lining the alveoli and students will discover that a single layer of flattened cells known as simple, squamous epithelium acts to reduce the diffusion distance. Again, students will have met this in a lesson in topic 2 on specialised cells (and tissues) so a number of prior knowledge checks are used alongside current understanding checks. The following features of the alveolar epithelium are also covered: Surface area Moist lining Production of surfactant The maintenance of a steep concentration gradient As a constant ventilation supply is critical for the maintenance of the steep concentration gradient, the final task considers the mechanism of ventilation

This lesson describes the adaptations of gas exchange surfaces in single-celled organisms, insects, bony fish and dicotyledonous plants. The PowerPoint and accompanying worksheets are part of the first lesson in a series of 6 lessons that have been designed to cover the detail of point 3.2 (Gas exchange) of the AQA A-level Biology specification. The lesson has been intricately planned to challenge the students on their understanding of the surface area to volume ratio (as covered in the previous lesson) and to make direct links to upcoming lessons on gas exchange and transport systems in humans. The lesson begins by explaining that single-celled organisms are able to diffuse oxygen and carbon dioxide across their body surface but that as organisms increase in size and their SA/V ratio decreases, they need adaptations at their gas exchange surfaces to be able to obtain the oxygen to meet their metabolic demands. This leads into the next part of the lesson which describes the roles of the following structures in insects and bony fish: spiracles, tracheae, tracheoles and tracheole fluid operculum, gill arch, gill filaments and lamellae The next task challenges the students to use their knowledge of topics 1 and 2 to come up with the letters that form the key term, countercurrent flow. This is a key element of the lesson and tends to be a principle that is poorly understood, so extra time is taken to explain the importance of this mechanism. Students are shown two diagrams, where one contains a countercurrent system and the other has the two fluids flowing in the same direction, and this is designed to support them in recognising that this type of system ensures that the concentration of oxygen is always higher in the oxygenated water than in the blood in the lamellae. The final part of the lesson describes the role of the stomata and the mesophyll cells in the gas exchange of a dicotyledonous plant. Students will learn that guard cells contain chloroplasts which generate ATP and then they are challenged to order a series of statements to form a description of the events that result in the opening of the stomata. The differing structures of the spongy mesophyll and palisade mesophyll cells are then considered before the students are challenged to explain how carbon dioxide moves through the leaf after entering via the stomata and then how water vapour and oxygen leave. Clear links are made to the loss of water vapour by transpiration so students are prepared for the lessons covering this biological process later in topic 3.

This lesson describes the roles of the buccal cavity, operculum, gill lamellae and countercurrent flow in ventilation and gas exchange in bony fish. The detailed PowerPoint and accompanying resources are part of the first lesson in a series of 2 that have been designed to cover the details of point 3.1.1 (f) of the OCR A-level Biology A specification. The second lesson in this series covers the mechanisms of ventilation and gas exchange in insects. The lesson has been specifically planned to prepare students for the content of module 3.1.2 (Transport in animals) and therefore begins with an introduction and a brief description of the single circulatory system of a fish as this has an impact on the delivery of deoxygenated blood to the lamellae. A quick quiz competition is used to introduce the operculum and then the flow of blood along the gill arch and into the primary lamellae and then into the capillaries in the secondary lamellae is described. The next task challenges the students to use their knowledge of module 2 to come up with the letters that form the key term, countercurrent flow. This is a key element of the lesson and tends to be a feature that is poorly understood, so extra time is taken to explain the importance of this mechanism. Students are shown two diagrams, where one contains a countercurrent system and the other has the two fluids flowing in the same direction, and this is designed to support them in recognising that this type of system ensures that the concentration of oxygen is always higher in the oxygenated water than in the blood in the lamellae. The remainder of the lesson focuses on the coordinated movements of the buccal-opercular pump to ensure that the water continues to flow over the gills. Current understanding and prior knowledge checks are included throughout the lesson and students can assess their progress against the mark schemes which are embedded into the PowerPoint

This lesson explains the meaning of biodiversity and describes how it can be assessed in a habitat, in a species level at a genetic level and at a molecular level. The engaging PowerPoint and accompanying resources have been designed to cover points (h-l) in AS unit 2, topic 1 of the WJEC A-level Biology specification but as a lot of genetic content is covered when considering diversity within a species, this lesson can be used as an introduction to the upcoming topics of inheritance A quiz competition called BIOLOGICAL TERMINOLOGY SNAP runs over the course of the lesson and this will engage the students whilst challenging them to recognise key terms from their definitions. This quiz introduces biodiversity, loci, allele and recessive and each of these terms is put into context once introduced. Once biodiversity has been revealed, the students will learn that they are expected to be able to assess the biodiversity within a habitat and within a species and at a molecular level. The variety of alleles in the gene pool of a population increases the genetic diversity so a number of examples are used to demonstrate how the number of phenotypes increases with the number of alleles at a locus. The CFTR gene is used to demonstrate how 2 alleles results in 2 different phenotypes and therefore genetic diversity. Moving forwards, students will discover that more than 2 alleles can be found at a locus and they are challenged to work out genotypes and phenotypes for a loci with 3 alleles (shell colour in snails) and 4 alleles (coat colour in rabbits). Moving forwards, a step by step guide to complete a worked example to calculate a value of D using Simpson’s index of diversity. Students are challenged with a range of exam-style questions where they have to apply their knowledge and all mark schemes are displayed and clearly explained within the PowerPoint to allow students to assess their understanding and address any misconceptions if they arise. The final part of the lesson considers how DNA fingerprinting can be used to assess biodiversity at a molecular level and again a series of exam-style questions are used to challenge the students to apply their newly-acquired knowledge to an unfamiliar situation.

This lesson introduces the three-domain system and describes some of the biochemical methods used in classification to overcome the problems of morphological convergence. The PowerPoint and accompanying resources have been designed to cover points [c] and [e] in AS unit 2, topic 1 of the WJEC A-level Biology specification The lesson begins with an introduction of Carl Woese and goes on to describe how he is most famous for his definition of the Archaea as a new domain of life. Students were introduced to domains and the other classification taxa in a previous lesson, so their recall of this knowledge is continually tested and built upon as details are added. Students will discover the key differences between Archaea and Bacteria that led to the splitting of the prokaryotae kingdom and the addition of this higher classification rank. Moving forwards, the rest of the lesson considers other molecules that can be compared between species for classification purposes and the primary structure of cytochrome is described and discussed. At this point in the lesson, the students are also tested on their knowledge of the nature of the genetic code and have to explain how mutations to DNA can also be used for comparative purposes. The use of DNA genetic fingerprinting is briefly introduced and this is described in greater detail in a future lesson about assessing biodiversity at a molecular level

This lesson describes how biodiversity is generated through natural selection and leads to behavioural, anatomical and physiological adaptations. The PowerPoint and accompanying resources have been designed to cover specification points (m) & (n) in AS unit 2, topic 1 of the WJEC A-level Biology specification President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. Moving forwards, 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of evolution through natural selection. The main task of the lesson challenges the students to form a description that explains how this strain of bacteria developed resistance to methicillin to enable them to see the principles of natural selection. This can then be used when describing how the anatomy of the modern-day giraffe has evolved over time. The concept of convergent evolution is introduced and links are made to the need for modern classification techniques as covered earlier in topic 1. Moving forwards, students will understand how natural selection leads to adaptations and a quick quiz competition introduces the different types of adaptation and a series of tasks are used to ensure that the students can distinguish between anatomical, behavioural and physiological adaptations. The Marram grass is used to test their understanding further, before a step by step guide describes how the lignified cells prevent a loss of turgidity. Moving forwards, the students are challenged to explain how the other adaptations of this grass help it to survive in its environment. A series of exam-style questions on the Mangrove family will challenge them to make links to other topics such as osmosis and the mark schemes are displayed to allow them to assess their understanding. The final part of the lesson focuses on the adaptations of the anteater but this time links back to the topic of taxonomy and students have to answer questions about species and classification hierarchy. Due to the extensiveness of this lesson and the detail contained within the resources, it is estimated that it will take in excess of 2 hours of allocated A-level teaching time to deliver this lesson.

This lesson describes the characteristic features of the Animalia, Plantae, Fungi, Protoctista and Prokaryotae kingdoms. The engaging PowerPoint and accompanying resources have been designed to cover point (d) in AS unit 2, topic 1 of the WJEC A-level Biology specification This lesson begins with a knowledge recall as students have to recognise that prior to 1990, kingdom was the highest taxa in the classification hierarchy. Moving forwards, they will recall the names of the five kingdoms and immediately be challenged to split them so that the prokaryotae kingdom is left on its own. An opportunity is taken at this point to check on their prior knowledge of the structure of a bacterial cell as covered in unit 1, topic 2. These prior knowledge checks are found throughout the lesson (along with current understanding checks) as students are also tested on their knowledge of the structure and function of cellulose. This is found in the section of the lesson where the main constituent of the wall can be used to distinguish between plantae, fungi and prokaryotae. Quick quiz competitions, such as YOU DO THE MATH and SAY WHAT YOU SEE are used to introduce key values and words in a fun and memorable way. The final part of the lesson looks at the protoctista kingdom and students will come to understand how these organisms tend to share a lot of animal or plant-like features. Both of the accompanying resources have been differentiated to allow students of differing abilities to access the work and this lesson has been written to tie in with the previously uploaded lesson on classification and the binomial naming system

This lesson describes the classification system, focusing on the biological classification of a species and the 7 taxa found above this lowest taxon. The engaging PowerPoint and accompanying resource have been designed to cover points (a), (b), (f) & (g) in AS unit 2, topic 1 of the WJEC A-level Biology specification and also describes the binomial naming system which uses the genus and species. The lesson also contains links to upcoming lessons where the three-domain classification system and the characteristics of the five kingdoms are covered. The lesson begins by looking at the meaning of a population in Biology so that the term species can be introduced. A hinny, which is the hybrid offspring of a horse and a donkey, is used to explain how these two organisms must be members of different species because they are unable to produce fertile offspring. Moving forwards, students will learn that classification is a means of organising the variety of life based on relationships between organisms using differences and similarities in phenotypes and in genotypes and is built around the species concept and that in the modern-day classification hierarchy, species is the lowest taxon. A quiz runs throughout the lesson and this particular round will engage the students whilst they learn (or recall) the names of the other 7 taxa and the horse and the donkey from the earlier example are used to complete the hierarchy. Students will understand that the binomial naming system was introduced by Carl Linnaeus to provide a universal name for each species and they will be challenged to apply their knowledge by completing a hierarchy for a modern-day human, by spotting the correct name for an unfamiliar organism and finally by suggesting advantages of this system.

This lesson describes the structures and functions of the components of the mammalian gaseous exchange system. The PowerPoint and accompanying resources have been designed to cover point 3.1.1 [c] of the OCR A-level Biology A specification and contains links to future topics such as transport in animals as well as prior knowledge checks of their recall of the content of previously covered modules. The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features: The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea The narrowing airways of the primary, secondary and tertiary bronchi The elastic fibres and smooth muscle in the terminal and respiratory bronchioles and the change from simple columnar epithelium to simple cuboidal epithelium The large surface area to volume ratio and the simple squamous epithelium of the alveoli The pleural cavity and fluid of the lungs When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for module 6.1.2 (Patterns of inheritance)

This lesson describes the gross structure of the human gas exchange system and the functions of the structural components like goblet cells. The PowerPoint and accompanying resources have been designed to cover points 9.1 (a & c) of the CIE A-level Biology specification and has been specifically planned to prepare students for an upcoming lesson where the gas exchange between the alveoli and the blood is described. The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features: The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea The narrowing airways of the primary, secondary and tertiary bronchi The elastic fibres and smooth muscle in the terminal and respiratory bronchioles The pleural cavity and fluid of the lungs When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for topic 16 (Inherited change)

This lesson describes the gross structure of the human gas exchange system, including the trachea, bronchi, bronchioles and lungs. The PowerPoint and accompanying resources are part of the third lesson in a series of 6 which have been designed to cover the detail of topic 3.2 in the AQA A-level Biology specification which is titled gas exchange and this lesson has been specifically planned to prepare students for the next lesson where the essential features of the alveoli are described. The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features: The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea The narrowing airways of the primary, secondary and tertiary bronchi The elastic fibres and smooth muscle in the terminal and respiratory bronchioles The pleural cavity and fluid of the lungs When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for the topic of inheritance (7.1)