This lesson has been written to cover the part of specification point 6.4.3 of the AQA A-level Biology specification which states that students should be able to describe how water and glucose are reabsorbed in the proximal convoluted tubule. It has specifically been designed to build on the knowledge gained in the previous lessons on the structure of the nephron and ultrafiltration. The lesson begins by challenging the students to recall the substances that are found in the glomerular filtrate so that each of them can be considered over the course of the rest of the lesson. Moving forwards, the first of the numerous discussion points which are included in the lesson is used to get students to predict the component of the filtrate which won’t be found in the urine when they are presented with pie charts from each of these situations. Upon learning that glucose is 100% reabsorbed, along with most of the ions and some of the water, the rest of the lesson focuses on describing the relationship between the structure of the PCT and the function of selective reabsorption. Again, this section begins by encouraging the students to discuss and to predict which structures they would expect to find in a section of the kidney if the function is to reabsorb. They are given the chance to see the structure (as shown in the cover image) before each feature is broken down to explain its importance. Time is taken to look at the role of the cotransporter proteins to explain how this allows glucose, along with sodium ions, to be reabsorbed from the lumen of the PCT into the epithelial cells. The final part of the lesson focuses on urea and how the concentration of this substance increases along the tubule as a result of the reabsorption of some of the water. This lesson has been designed for students studying on the AQA-A level Biology course and ties in nicely with the other lessons from 6.4.3 as well as the other uploaded lessons from topic 6

This engaging and fully-resourced lesson looks at the myogenic nature of cardiac muscle and explores the roles of the SAN, AVN and Purkyne tissue in the initiation and control of heart action. The PowerPoint and accompanying resources have been designed to cover points 8.2 (d) of the CIE International A-level Biology specification. The lesson begins with the introduction of the SAN as the natural pacemaker and then time is given to study each step of the conduction of the impulse as it spreads away from the myogenic tissue in a wave of excitation. The lesson has been written to make clear links to the cardiac cycle and the structure of the heart and students are challenged on their knowledge of this system from topic 8.1. Moving forwards, students are encouraged to consider why a delay would occur at the AVN and then they will learn that the impulse is conducted along the Bundle of His to the apex so that the contraction of the ventricles can happen from the bottom upwards. The structure of the cardiac muscle cells is discussed and the final task of the lesson challenges the students to describe the conducting tissue, with an emphasis on the use of key terminology Due to the detailed nature of this lesson, it is estimated that it will take about 2 hours of A-level teaching time to cover the detail

This fully-resourced lesson looks at the double, closed circulatory system as found in a mammal and considers how the pulmonary circulation differs from the systemic circulation. The engaging PowerPoint and accompanying resources have been designed to cover point 8.1 (a) of the CIE International A-level Biology specification The lesson begins with a focus on the meaning of a double circulatory system and checks that students are clear in the understanding that the blood passes through the heart twice per cycle of the body. Beginning with the pulmonary circulation, students will recall that the pulmonary artery carries the blood from the right ventricle to the lungs. An opportunity is taken at this point to check on their knowledge of inhalation and the respiratory system as well as the gas exchange between the alveoli and the capillary bed. A quick quiz is used to introduce arterioles and students will learn that these blood vessels play a crucial role in the changes in blood pressure that prevent the capillaries from damage. When looking at the systemic circulation, time is taken to look at the coronary arteries and renal artery as students have to be aware of these vessels in addition to the ones associated with the heart. In the final part of the lesson, students are challenged to explain how the structure of the heart generates a higher pressure in the systemic circulation and then to explain why the differing pressures are necessary. As a result of the constant reference to the heart, the blood vessels and the blood, students will be reminded that these are the components of the circulatory system

This fully-resourced looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration effects the dissociation of adult oxyhaemoglobin. The PowerPoint and accompanying resources have been designed to cover point 8.1 (g) of the CIE International A-level Biology specification and continually ties in with the previous lesson on the role of haemoglobin in carrying oxygen. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual.

This detailed lesson describes the role of the strand of mRNA, the tRNA molecules, the amino acids and the ribosome during the second stage of protein synthesis - translation. Both the PowerPoint and accompanying resources have been designed to cover the second part of point 6.2 (d) of the CIE International A-level Biology specification and ties in with the first part of this specification point which covered transcription. Translation is a topic which is often poorly understood and so this lesson has been written to enable the students to understand how to answer the different types of questions by knowing and including the key details of the structures involved. The lesson begins by challenging the students to consider why it is so important that the amino acids are assembled in the correct order during the formation of the chain. Moving forwards, a quick quiz round called “LOST IN TRANSLATION” is used to check on their prior knowledge of the mRNA strand, the tRNA molecules, the genetic code and the ribosomes. The next task involves a very detailed description of translation that has been divided into 14 statements which the students have to put into the correct order. By giving them a passage that consists of this considerable detail, they can pick out the important parts to use in the next task where they have to answer shorter questions worth between 3 and 4 marks. These types of questions are common in the assessments and by building up through the lesson, their confidence to answer this type should increase. The final two tasks of the lesson involve another quiz called “The protein synthesis game”, where the teams compete to transcribe and translate in the quickest time before using all the information from the lessons on protein synthesis to answer some questions which involve the genetic code and the mRNA codon table.

Amino acids are the monomers of polypeptides and this lesson describes their structure and makes links to related topics such as genes and dipeptides. The engaging PowerPoint has been designed to cover the first part of point 1.4.1 of the AQA A-level Biology specification and provides a clear introduction to the following lesson on the formation of dipeptides and polypeptides. The lesson begins with a prior knowledge check, where the students have to use the 1st letters of 4 answers to uncover a key term. This 4-letter key term is gene and the lesson begins with this word because it is important for students to understand that these sequences of bases on DNA determine the specific sequence of amino acids in a polypeptide. Moving forwards, students are given discussion time to work out that there are 64 different DNA triplets and will learn that these encode for the 20 amino acids that are common to all organisms. The main task of the lesson is an observational one, where students are given time to study the displayed formula of 4 amino acids. They are not allowed to draw anything during this time but will be challenged with 3 multiple choice questions at the end. This task has been designed to allow the students to visualise how the 20 amino acids share common features in an amine and an acid group. A quick quiz round introduces the R group and time is taken to explain how the structure of this side chain is the only structural difference, before cysteine is considered in greater detail due to the presence of sulfur atoms. Students are briefly introduced to disulfide bridges so they will recognise how particular bonds form between the R groups in the tertiary structure which is covered in the next lesson. The lesson concludes with one more quiz round called LINK TO THE FUTURE where the students will see the roles played by amino acids in the later part of the course such as translation and mineral ions.

This fully-resourced lesson describes the behaviour of chromosomes during interphase, mitosis and cytokinesis in the cell cycle. The detailed PowerPoint and accompanying resources have been designed to cover the first half of point 2.2 as detailed in the AQA A-level Biology specification whereas uncontrolled cell division and cancer and binary fission are covered in upcoming lessons. Depending upon the exam board taken at GCSE, the knowledge and understanding of mitosis and the cell cycle will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson and to address existing errors, key points are emphasised throughout. The cell cycle is introduced at the start of the lesson and the quantity of DNA inside the parent cell is described as diploid and as 2n. A quiz competition has been written into the lesson and this runs throughout, challenging the students to identify the quantity of DNA in the cell (in terms of n) at different points of the cycle. Moving forwards, the first real focus is interphase and the importance of DNA replication is explained so that students can initially recognise that there are pairs of identical sister chromatids and then can understand how they are separated later in the cycle. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. Centrioles were not covered in the topic 2.1 lessons on cell structures so a quick task will introduce them to these organelles who are responsible for the production of the spindle apparatus, Students will understand how the cytoplasmic division that occurs in cytokinesis results in the production of genetically identical daughter cells. This leads into a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture.

This fully-resourced lesson guides students through the construction of genetic crosses and pedigree diagrams for the inheritance of a single gene. The clear PowerPoint and accompanying resources have been designed to cover point 8.2 (ii) of the Edexcel A-level Biology B specification and includes the inheritance of multiple allele characteristics as well as those that demonstrate codominance. In order to minimise the likelihood of errors and misconceptions, step by step guides have been included throughout the lesson to support the students with the following: Writing parent genotypes Working out the different gametes that are made following meiosis Interpreting Punnett crosses to work out phenotypic ratios Students can often find pedigree trees the most difficult to interpret and to explain so exemplar answers are used as well as differentiated worksheets provided to support those students who need extra assistance.

This resource contains an engaging and detailed lesson PowerPoint and accompanying worksheets which cover the content of both the Core and Supplement sections of topic 14.2 (Sense organs) as detailed in the CIE IGCSE Biology specification. Understanding checks are included at regular points throughout the lesson to allow the students to self-assess their progress and quiz competitions like SAY WHAT YOU SEE and LOOK into these WORDS introduce key terms in a fun and memorable way. The following content is covered across this resource: The function of the cornea, retina, lens, optic nerve and iris Identifying these structures and the pupil, fovea and blind spot on a diagram The roles of the rods and cones in the retina and their distribution Explain the pupil reflex in terms of the antagonistic action of the muscles in the iris Accommodation to view near and distant objects Sense organs and the stimuli to which they respond This lesson has been designed for GCSE-aged students who are studying the CIE IGCSE Biology course but is suitable for both younger and older students who are studying this organ

This fully-resourced lesson has been designed to cover the content of specification point 5.2.2 (The brain) as found in topic 5 of the AQA GCSE Biology specification. This resource contains an engaging PowerPoint (33 slides) and accompanying worksheets, some of which have been differentiated so that students of different abilities can access the work. The resource is filled with a wide range of activities, each of which has been designed to engage and motivate the students whilst ensuring that the key Biological content is covered in detail. Understanding checks are included throughout so that the students can assess their grasp of the content. In addition, previous knowledge checks make links to content from earlier topics such as cancer. The following content is covered in this lesson: The functions of the cerebral cortex, medulla and cerebellum Identification of the regions of the brain on an external and internal diagram The early use of stroke victims to identify functions The key details of the MRI scanning technique The difficulties of diagnosing and treating brain disorders and disease As stated at the top, this lesson has been designed for GCSE-aged students who are studying the AQA GCSE Biology course, but it can be used with A-level students who need to go back over the key points before looking at the functionality of the regions in more detail

This lesson has been designed to cover the content in specification point 17.3 (Mitosis) which is part of topic 17 (Inheritance) of the CIE IGCSE Biology specification. A wide range of activities have been written into the lesson to motivate and engage the students whilst ensuring that the following content of both the Core & Supplement sections are covered in detail. The duplication of chromosomes before mitosis Mitosis is a form of division that results in genetically identical cells The important roles of mitosis for living organisms Stem cells use mitosis before differentiation to produce specialised cells Understanding checks have been included in the lesson at regular points to allow the students to assess their understanding as well as previous knowledge checks to topics like organelles in animal and plant cells. This lesson has been designed for GCSE-aged students but is suitable for older students who are studying mitosis at A-level and need to recall the key points

This lesson explains why the conduction of an impulse along myelinated neurones is faster than along unmyelinated neurones. The PowerPoint and accompanying resources have been written to cover point (7) of topic 15.1 of the CIE A-level Biology specification. A wide range of activities are included in this lesson to maintain the motivation of the students whilst ensuring that the detail is covered in depth. Interspersed with the activities are understanding checks and prior knowledge checks to allow the students to not only assess their understanding of the current topic but also challenge themselves to make links to earlier topics such as the movement of ions across membranes and biological molecules. Over the course of the lesson, students consider the structure of the myelin sheath and specifically how the electrical insulation is not complete all the way along. This leaves gaps, known as the nodes of Ranvier, which allow the entry and exit of ions. Saltatory conduction can be poorly explained by a lot of students so time is taken to look at the way that the action potential jumps between the nodes and this is explained further by reference to local currents. The rest of the lesson focuses on the other two factors which are axon diameter and temperature and students are challenged to discover these two by focusing on the vampire squid.

A highly engaging lesson presentation (74 slides) and accompanying worksheets that uses exam questions (with explained answers), quick tasks and quiz competitions to allow students to assess their understanding of the topic of Biological molecules (Topic 3.1). Students will have fun whilst recognising those areas of the specification which need further attention.

This is a detailed, engaging and fully-resourced REVISION LESSON which allows students of all abilities to assess their understanding of the content in module 2.1.3 (Nucleotides and nucleic acids) of the OCR A-level Biology A specification. Considerable time has been taken to design the lesson to include a wide range of activities to motivate the students whilst they evaluate their knowledge of DNA, RNA and the roles of these nucleic acids in DNA replication and protein synthesis. Most of the tasks have been differentiated so that students of differing abilities can access the work and move forward as a result of the tasks at hand. This lesson has been planned to cover as much of the specification as possible but the following sub-topics have received particular attention: The structure of DNA Phosphorylated nucleotides DNA replication Transcription and translation Gene mutations and their affect on the primary structure of a polypeptide The structure of RNA In addition to a focus on the current topic, links are made throughout the lesson to other topics such as the journey of an extracellular protein following translation and the cell cycle. If you like the quality of this revision lesson, please look at the other uploaded revision lessons for this module and for this specification

A fun and engaging lesson presentation (33 slides) and associated worksheet that uses exam questions, with fully explained answers, quick tasks and competitions to allow students to assess their understanding of Module 3.1.2 (Transport in Animals). The students will enjoy the lesson whilst being able to recognise which areas of the specification need further attention. Competitions included in the lesson are “SPOT THE ERROR”, “Where’s Lenny” and “Crack the code”

An engaging lesson presentation (61 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B2 (Organisation) of the AQA GCSE Biology specification (specification point 4.2) The topics that are tested within the lesson include: Principles of organisation The human digestive system The heart and blood vessels Blood Coronary heart disease The effect of lifestyle on some non-communicable diseases Plant organ systems Students will be engaged through the numerous activities including quiz rounds like “SPOT the SUBSTANCE" and “Where’s LENNY” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (68 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within the Biology topic B4 (Bioenergetics) of the AQA GCSE Combined Science specification (specification unit B4.4). The topics that are tested within the lesson include: Photosynthesis reaction Rate of photosynthesis Uses of glucose from photosynthesis Aerobic respiration Anaerobic respiration Response to exercise Students will be engaged through the numerous activities including quiz rounds like “Take a STEP back” and “Shine a LIGHT on the errors” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (60 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B2 (Organisation) of the AQA GCSE Combined Science specification (specification point 4.2) The topics that are tested within the lesson include: Principles of organisation The human digestive system The heart and blood vessels Blood Coronary heart disease The effect of lifestyle on some non-communicable diseases Plant organ systems Students will be engaged through the numerous activities including quiz rounds like “SPOT the SUBSTANCE" and “Where’s LENNY” whilst crucially being able to recognise those areas which need further attention