This is an informative lesson that builds on the knowledge that students gained at GCSE on the topic of inheritance to enable them to carry out genetic crosses for the inheritance of a single gene at A-level. The start of the lesson focuses on the terminology that is associated with this topic which has to be recognised and understood if students are going to be able to begin a cross. Time is taken to go over key points such as the genotypes and working out the different possible gametes that would be produced by meiosis. Students can save time by only showing the different gametes so assistance is given on this. As can be seen from the cover image, a step by step guide is used to go through a number of examples so that students can visualise how to set out their diagrams in order to maximise the marks gained. There are progress checks written into the lesson throughout so that assessment is constant. This lesson can be taught alongside another upload called “understanding genetic trees”

This extensive and fully-resourced lesson describes the principles and explains the techniques used in the production of recombinant DNA in genetic engineering. Both the engaging PowerPoint and accompanying resources have been written to cover points 6.1.3 (f) (i & ii) of the OCR A-level Biology A specification. The lesson begins with a definition of genetic engineering and recombinant DNA to allow students to begin to understand how this process involves the transfer of DNA fragments from one species to another. Links are made to the genetic code and transcription and translation mechanisms, which were met in module 2, in order to explain how the transferred gene can be translated in the transgenic organism. Moving forwards, the method involving reverse transcriptase and DNA polymerase is introduced and their knowledge of the structure of the polynucleotides and the roles of enzymes is challenged through questions and discussion points. Restriction enzymes are then introduced and time is taken to look at the structure of a restriction site as well as the production of sticky ends due to the staggered cut on the DNA. A series of exam-style questions with displayed mark schemes are used to allow the students to assess their current understanding. The second half of the lesson looks at the culture of transformed host cells as an in vivo method to amplify DNA fragments. Students will learn that bacterial cells are the most commonly transformed cells so the next task challenges their recall of the structures of these cells so that plasmid DNA can be examined from that point onwards. The following key steps are described and explained: • Remove and prepare the plasmid to act as a vector • Insert the DNA fragment into the vector • Transfer the recombinant plasmid into the host cell • Identify the cells which have taken up the recombinant plasmid • Allow the transformed host cells to replicate and express the novel gene Time is taken to explore the finer details of each step such as the addition of the promoter and terminator regions, use of the same restriction enzyme to cut the plasmid as was used to cut the gene and the different types of marker genes. As well as understanding and prior knowledge checks, quick quiz competitions are used throughout the lesson to introduce key terms such as cDNA and EcoR1 in a memorable way.

This is an engaging and informative lesson that looks at the wires inside a UK plug and considers their role in terms of the supply of mains electricity. The safety features of the plug, such as the fuse, are also discussed so that students can understand how a particular fuse is chosen. As the cover image shows, the lesson begins by challenging the students to use their knowledge of all three of the Sciences to come up with the three names of the wires. Some students will know that these are the wires in a UK plug but some wont. Key terminology such as three-core cable is used throughout, as well as a running theme with the colours, so that students become accustomed to identifying a particular wire by its plastic insulation. Through a range of tasks which encourage student discovery and educated predictions, the students will learn the functions of each of the wires as well as their potential difference. The fuse is introduced to the students and links are made to the electrical circuits topic by considering the resistance of the wire inside the fuse and challenging them to use the electrical power equation to calculate a current and choose an appropriate fuse for that plug. The aim of the lesson is to get students to absorb information as the lesson progresses in order to eventually label a black and white diagram of the plug. The last part of the lesson looks at two-core cables and then relates this back to the importance of the earth wire in a UK plug. This lesson has been written for GCSE aged students but is suitable for use with younger students who are learning about this topic.

This is a fully-resourced lesson that uses a variety of tasks and quick competitions to look at what happens to sound waves when they hit a boundary and how these properties are utilised for numerous functions and appliances. This lesson includes an engaging and informative lesson presentation (32 slides) and a worksheet which is differentiated two ways to enable students who are finding the topic difficult a chance to access the learning. The lesson begins by looking at how sound waves can be reflected and how this is commonly known as an echo. Students are challenged to use a provided equation to calculate a distance by using the time that the echo of a shout takes to be heard in the Grand Canyon. Moving forwards, students will see how this idea of reflection can be used with ultrasound in the imaging of the foetus. At this stage, as the cover image shows, students are challenged to complete a doctor’s letter to an expectant mother who is concerned about the ultrasound procedure. Assistance is given in the form of a differentiated worksheet for those who find it difficult. Moving forwards, students will learn that sound waves can be refracted at a boundary, just as light waves can. Working with the teacher, they will use key terms to build up an exemplar definition to explain how this refraction occurs. This lesson has been designed for GCSE aged students.

This is a fully-resourced lesson that looks at the role of transformers in the National Grid, explains why they increase or decrease potential difference and then uses the given equation to calculate potential difference or the number of turns on the primary or secondary coil. This lesson includes an informative lesson presentation (25 slides) and two question worksheets. The lesson begins by introducing the devices that are transformers and showing the students that there are two types, step-up and step-down. Students will learn that step-up transformers increase the potential difference and step-down transformers decrease the potential difference. Moving forwards, a series of calculations are used to get the students to understand why these changes in potential difference occur. Students are guided through this section so that they are able to complete a summary passage about the roles of these devices. They will then be shown the equation connecting potential difference and number of turns which they do not need to recall but have to apply. Again, a worked example is used to visualise how workings should be set out before students are challenged to answer two sets of questions, the second of which involves the use of a second equation. Progress checks like these are found at regular intervals throughout the lesson so that students can assess their understanding. This lesson has been written for GCSE students

This fully-resourced lesson explores how the structure of arteries, arterioles, capillaries, venules and veins relate to their functions. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 3.1.2 © of the OCR A-level Biology A specification. This lesson has been written to build on any prior knowledge from GCSE or earlier in this topic to enable students to fully understand why a particular type of blood vessel has particular features. Students will be able to make the connection between the narrow lumen and elastic tissue in the walls of arteries and the need to maintain the high pressure of the blood. A quick version of the GUESS WHO game is used to introduce smooth muscle and collagen in the tunica media and externa and again the reason for their presence is explored and explained. Moving forwards, it is quite likely that some students will not be aware of the transition vessels that are the arterioles. This section begins with an understanding of the need for these vessels because the structural and functional differences between arteries and capillaries is too significant. The action of the smooth muscle in the walls of these vessels is discussed and students will be challenged to describe a number of situations that would require blood to be redistributed. The middle part of the lesson looks at the role of the capillaries in exchange and links are made to diffusion to ensure that students can explain how the red blood cells pressing against the endothelium results in a short diffusion distance. The remainder of the lesson considers the structure of the veins and students are challenged to explain how the differences to those observed in arteries is due to the lower blood pressure found in these vessels. It is estimated that it will take at least 2 hours of allocated A-level Biology teaching time to cover the detail included in this lesson

This is a fast-paced lesson that explores the structural differences (and similarities) between sensory and motor neurones. The lesson uses a range of tasks, progress checks and quick competitions to enable the students to recognise how these neurones differ in terms of the cell body, axon and dendron. Students will also understand that both neurones are myelinated which allows saltatory conduction to occur. Relay neurones are briefly discussed during the final section of the lesson. This lesson has primarily been designed for A-level students but can be used with the content means that it is suitable for use with GCSE students too who are studying the nervous system.