This fully-resourced lesson explores the relationship between the structure of arteries, arterioles and veins and their respective functions. The engaging and detailed PowerPoint and accompanying resources have been designed to cover the 6th part of point 3.4.1 of the AQA A-level Biology specification which states that students should be able to describe the structure of these blood vessels in relation to their function. This lesson has been written to build on any prior knowledge from GCSE or earlier in this topic to enable students to fully understand why a particular type of blood vessel has particular features. Students will be able to make the connection between the narrow lumen and elastic tissue in the walls of arteries and the need to maintain the high pressure of the blood. A quick version of the GUESS WHO game is used to introduce smooth muscle and collagen in the tunica media and externa and again the reason for their presence is explored and explained. Moving forwards, the importance of the arterioles as a transition between the artery and capillary is discussed and students will see how the smooth muscle in the walls of this blood vessel allows for the redistribution of blood during exercise. The final part of the lesson considers the structure of the veins and students are challenged to explain how the differences to those observed in arteries is due to the lower blood pressure found in these vessels. It is estimated that it will take about 2 hours of allocated A-level Biology teaching time to cover the detail included in this lesson

This lesson explains the law of conservation of mass and applies this law to a closed system and a non-enclosed system. The PowerPoint and accompanying resources have been designed to cover point 1.48 of the Edexcel GCSE Chemistry specification and also covers that point in the Chemistry section of the Combined Science course. The lesson begins by introducing the law of the conservation of mass. Students will learn that they can expect questions which challenge them to prove that mass is conserved through the use of the relative formula mass. Therefore, the next section of the lesson focuses on the skills associated with this calculation and looks at more different formulae such as those with brackets. Students are given an opportunity to check their skills before trying to prove mass is conserved in three chemical reactions. All questions have displayed mark schemes so that students can assess their understanding. The rest of the lesson looks at instances of when the mass of the reactants does not equal the mass of the products. A practical method for the decomposition of copper carbonate is provided if the teacher wants to use it, so that students can collect results which show this difference in mass. Discussions are encouraged in order to get students to offer explanations as to why the mass of the products is lower. Once the gas has been identified, students are further challenged to consider apparatus that could be used to collect and record the results to again prove conservation

This is a highly detailed, engaging and fully-resourced lesson that covers the detail of the 2nd part of specification point 5.1.2 (b) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the functions of the mammalian liver. The liver performs a large number of metabolic functions and the majority of them are covered within this lesson. However, the lesson focuses on the following three roles: The formation of urea by deamination and the ornithine cycle The storage of glycogen The detoxification of alcohol As well as covering the detail of the current topic, numerous opportunities are taken to make links to other topics and to check on the students prior knowledge. Previous knowledge check questions on biological molecules, coenzymes and the structure of the liver are found dispersed within the understanding checks and quick quiz competitions are used to introduce key terms and values in a fun and a memorable way. This lesson has been designed for students on the OCR A-level Biology A course and ties in well with the other uploaded lessons on module 5.1.2 about the structure and function of the kidney

This is a highly-detailed and fully-resourced lesson which covers the detail of specification point 14.1 (g) of the CIE International A-level Biology specification which states that students should be able to describe the roles of the hypothalamus, posterior pituitary, ADH and collecting ducts in osmoregulation. Students learnt about the principles of homeostasis and negative feedback in an earlier lesson, so this lesson acts to build on that knowledge and challenges them to apply their knowledge. A wide range of activities have been included in the lesson to maintain motivation and engagement whilst the understanding and prior knowledge checks will allow the students to assess their progress as well as challenge themselves to make links to other Biology topics. The lesson begins with a discussion about how the percentage of water in urine can and will change depending on the blood water potential. Students will quickly be introduced to osmoregulation and they will learn that the osmoreceptors and the osmoregulatory centre are found in the hypothalamus. A considerable amount of time is taken to study the cell signalling between the hypothalamus and the posterior pituitary gland by looking at the specialised neurones (neurosecretory cells). Links are made to the topics of neurones, nerve impulses and synapses and the students are challenged to recall the cell body, axon and vesicles. The main section of the lesson forms a detailed description of the body’s detection and response to a low blood water potential. The students are guided through this section as they are given 2 or 3 options for each stage and they have to use their knowledge to select the correct statement. The final task asks the students to write a detailed description for the opposite stimulus and this task is differentiated so those who need extra assistance can still access the work. This lesson has been written for students studying on the CIE International A-level Biology course and ties in closely with the other uploaded lessons on the structure of the kidney, ultrafiltration and selective reabsorption

This lesson has been designed to cover the content as detailed in points 2.1, 2.2 and 2.3 (Mitosis as part of the cell cycle) of the Edexcel GCSE Biology & Combined Science specifications. Consisting of a detailed and engaging PowerPoint (44 slides) and an accompanying worksheet, the range of activities will motivate the students whilst ensuring that the content is covered in detail. Students will learn how interphase, the 4 phases of mitosis and cytokinesis result in the production of genetically identical diploid daughter cells. Time is taken to go through each of the three stages of the cell cycle in detail so students can recognise how the key events of each stage allow this important form of “copying” cell division to occur. Progress checks are included throughout the lesson so that students can assess their understanding of the content and any misconceptions can be addressed whilst quiz competitions, like The Big REVEAL and YOU DO THE MATH, are used to introduce new terms and important values in a fun and memorable way. This lesson has been written for GCSE-aged students who are studying the Edexcel GCSE Biology or Combined Science specifications but can be used with older students who need to know the key details of the cell cycle for their A level course before taking it to greater depths

This revision lesson has been designed to challenge the students on their use of a range of mathematical skills that could be assessed on the Edexcel GCSE Combined Science papers. The mathematical element of the Edexcel GCSE Combined Science course has increased significantly since the specification change and therefore success in those questions which involve the use of maths can prove to be the difference between one grade and another or possibly even more. The engaging PowerPoint and accompanying resources contain a wide range of activities that include exam-style questions with displayed mark schemes and explanations so that students can assess their progress. Other activities include differentiated tasks, class discussion points and quick quiz competitions such as “It doesn’t HURT to CONVERT”, “YOU DO THE MATH” and “FILL THE VOID”. The following mathematical skills (in a scientific context) are covered in this lesson: The use of Avogadro’s constant Rearranging the formula of an equation Calculating the amount in moles using mass and relative formula mass Calculating the relative formula mass for formulae with brackets Calculating the relative atomic mass using the mass and abundance of isotopes Using the Periodic Table to calculate the number of sub-atomic particles in atoms Changes to electrons in ions Balancing chemical symbol equations Empirical formula Converting between units Calculating concentration in grams per dm cubed and volumes of solutions Calculating size using the magnification equation Using the mean to estimate the population of a sessile species Calculating percentages to prove the importance of biodiversity Calculating percentage change The BMI equation Calculating the acceleration from a velocity-time graph Recalling and applying the Physics equations Understanding prefixes that determine size Leaving answers to significant figures and using standard form Helpful hints and step-by-step guides are used throughout the lesson to support the students and some of the worksheets are differentiated two ways to provide extra assistance. Due to the detail of this lesson, it is estimated that it will take in excess of 3 hours of GCSE teaching time to cover the tasks and for this reason it can be used over a number of lessons as well as during different times of the year for revision.

This fully-resourced lesson explores how genetic and environmental factors cause phenotypic variation. The engaging PowerPoint and accompanying worksheets have been designed to cover the first part of point 7.3 of the AQA A-level Biology specification which states that students should be able to describe how mutations and meiosis both contribute to genetic variation Students are challenged at the start of the lesson to recognise the terms phenotype and species from their definitions in order to begin a discussion on the causes of the phenotypic variation within a species. Moving forwards, students will recall that mutations are the primary source of genetic variation and time is taken to look at the effect of gene and chromosome mutations. Just like the majority of parts of this specification point, gene mutations were covered earlier in topic 4 so these tasks act as a prior knowledge check as students have to recognise the different types of gene mutations and explain their effects on the primary structure with reference to the genetic code. These prior knowledge checks are found throughout the lesson and challenge the knowledge of other topics that include photosynthesis, meiosis and inorganic ions. The karyotype of an individual who has Down syndrome is used to introduce chromosome mutations and students will be introduced to the different types, with a focus on non-disjunction. The key events of meiosis that produce variation (crossing over and independent assortment) are explored and students will be given a mathematical formula to use to calculate the number of chromosome combinations in gametes and in the resulting zygote. The final part of the lesson looks at chlorosis and how an environmental factor can prevent the express of a gene.

This lesson describes and explains how production is affected by a range of farming practices designed to increase the efficiency of energy transfer. The PowerPoint and accompanying resources are part of the third lesson in a series of 3 which have been designed to cover the detail included in specification point 5.3 of the AQA A-level Biology specification. Over the course of the lesson, a range of tasks which include exam-style questions with displayed mark schemes, guided discussion periods and quick quiz competitions will introduce and consider the following farming practices: raising herbivores to reduce the number of trophic levels in a food chain intensely rearing animals to reduce respiratory losses in human food chains the use of fungicides, insecticides and herbicides the addition of artificial fertilisers The ethical issues raised by these practices are also considered and alternative methods discussed such as the addition of natural predators and the use of organic fertilisers like manure As this is the last lesson in topic 5.3, it has been specifically planned to challenge the students on their knowledge of the previous two lessons and this includes a series of questions linking farming practice to the formula to calculate net production

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Topic 6 (Immunity, infection and forensics) of the Pearson Edexcel A-level Biology A specification. The sub-topics and specification points that are tested within the lesson include: Know how DNA profiling is used for identification and determining genetic relationships Know how DNA can be amplified using the PCR Know the structure of a virus Understand how HIV infects human cells, causing a sequence of symptoms that may result in death Understand the non-specific responses of the body to infection Understand the roles of antigens and antibodies in the body’s immune response Understand the differences between the roles of B cells and T cells Understand how one gene can give rise to more than one protein through post-transcriptional changes Understand the difference between bacteriostatic and bactericidal antibiotics Students will be engaged through the numerous quiz rounds such as “FROM NUMBERS 2 LETTERS” and “Make sure you are very SPECIFIC” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

A fully resourced lesson presentation (93 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit C3 (Chemical reactions) of the OCR Gateway A GCSE Combined Science specification. The topics that are tested within the lesson include: Formulae of elements and molecules Formulae of ionic compounds Conservation of mass Chemical equations Half equations The mole Exothermic and endothermic reactions The pH scale Hydrogen ions and pH Electrolysis of molten salts Electrolysis of solutions Students will be engaged through the numerous activities including quiz rounds like “E Numbers” whilst crucially being able to recognise those areas which need further attention

This is a detailed, engaging and fully-resourced REVISION LESSON which allows students of all abilities to assess their understanding of the content in topic 6 (Nucleic acids and protein synthesis) of the CIE International A-level Biology specification. Considerable time has been taken to design the lesson to include a wide range of activities to motivate the students whilst they evaluate their knowledge of DNA, RNA and the roles of these nucleic acids in DNA replication and protein synthesis. Most of the tasks have been differentiated so that students of differing abilities can access the work and move forward as a result of the tasks at hand. This lesson has been planned to cover as much of the specification as possible but the following sub-topics have received particular attention: The structure of DNA Phosphorylated nucleotides DNA replication Transcription and translation Gene mutations and their affect on the primary structure of a polypeptide The structure of RNA In addition to a focus on the current topic, links are made throughout the lesson to other topics such as the journey of an extracellular protein following translation and the cell cycle. If you like the quality of this revision lesson, please look at the other uploaded revision lessons for this specification

This lesson has been designed to cover the detail of specification point 4.5.3.2 of the AQA GCSE Combined Science FOUNDATION TIER which states that students should be able to describe how the body detects and responds to an increase in blood glucose concentration. A considerable amount of time has been taken in the planning to ensure that the wide range of activities engages and motivates the students but that the key details are covered and understanding is checked and checked again. The start of the lesson uses a range of prior knowledge checks and quiz competitions to answer the questions of what actually is glucose and why is it so important that the levels in the blood are controlled. Students are then introduced to glycogen and the fact that this carbohydrate can be stored is reiterated so that they can recognise how glucose must be converted into this substance to lower the blood concentration. Again, a quiz round is used to get them to recall that the pancreas will be the receptor and the liver will act as the effector. The main task of the lesson involves the formation of a bullet point answer where students are challenged to use the information from earlier in the lesson to complete this description.

This is a fully-resourced REVISION lesson that consists of an engaging PowerPoint (142 slides) and associated worksheets that challenge the students on their knowledge of topics B1 - B3 (Cell-level systems, Scaling up and Organism-level systems) of the OCR Gateway A GCSE Combined Science specification and can be assessed on PAPER 1. A wide range of activities have been written into the lesson to maintain motivation and these tasks include exam questions (with answers), understanding checks, differentiated tasks and quiz competitions. The lesson has been designed to include as much which of the content which could be assessed on paper 1, but the following sub-topics have been given particular attention: Eukaryotic and prokaryotic cells Structure of a bacterium The functions of the components of blood Specialised cells Active transport Osmosis Structure of DNA Mitosis and the cell cycle Functions of the organelles of animal and plant cells Electron microscopy Calculating size Surface area to volume ratio Arteries and veins Reflexes Hormones IVF The mathematic elements of the Combined Science specification are challenged throughout the resource. Due to the size of this resource, it is likely that it’ll be used over the course of a number of lessons and it is suitable for use as an end of topic revision aid, in the lead up to the mocks or in the lead up to the actual GCSE exams.

This lesson describes how to prepare and examine microscope slides and the use of staining in light microscopy. The PowerPoint and accompanying resources have been designed to cover points 2.1.1 (b & c) of the OCR A-level Biology A specification and describe how the eyepiece graticule and stage micrometer are used to measure the size of an object with a light microscope and the use of eosin and methylene blue. The main task of this lesson involves a step by step guide which walks students through the methodology and the use of the scale on the stage micrometer to identify the size of the divisions of the eyepiece graticule and this will need them to convert between units. Moving forwards, the students are challenged to apply this method to a series of exam-style questions and the mark scheme is displayed on the PowerPoint so that they can assess their understanding. In the last lesson, they were briefly introduced to the idea that some specimens need to be stained as light passes completely through transparent samples and the remainder of the lesson builds on this knowledge. Students will learn that cell populations, structures within cells and biological tissues can be distinguished using stains and a series of questions will challenge them to make links to biological molecules, organelles and infections. Links are also made to the upcoming topic of epithelial tissue in the respiratory system. This lesson has been specifically written to tie in with the previous lesson on light and electron microscopes and 2 rounds of the sub-module quiz competition are found in this lesson.

This lesson describes the importance of the cytoskeleton, and focuses on the role of these proteins in the transport within cells and cell movement. The PowerPoint and accompanying resource have been designed to cover point 2.1.1 (j) of the OCR A-level Biology A specification and has been specifically designed to tie in with The previous lesson covered the ultrastructure of eukaryotic cells and the function of the different cellular components and this lesson has been planned to build on that knowledge to show how the cytoskeleton allows for the movement of these organelles from one part of the cell to another. In particular, the students will recognise how the dragging movement of the motor proteins along the microtubule track is important for the proteins produced at the RER to move to the Golgi before the vesicles are then moved to the membrane for exocytosis. In this way, this lesson also covers specification point 2.1.1 (i). Other examples such as the movement of the synaptic vesicles and the contraction of the spindle fibres during anaphase are used to consolidate understanding further. The cilia and the flagellum are also described and links are made to related topics such as the primary non-specific defences against pathogens. In order to engage and motivate the students during the 7 lessons in this module, a running quiz competition has been written into each of the lessons and 3 rounds are incorporated into this lesson. A quiz scoresheet to keep track of the points is included in this resource.

This detailed and fully-resourced lesson describes the relationship between the structure and function of the polysaccharides: glycogen, starch and cellulose. The engaging PowerPoint and accompanying resources have been designed to cover point 1.1 (iv) as it is detailed in the Edexcel A-level Biology B specification and clear links are also made to the previous lessons in this topic where the monosaccharides and disaccharides were introduced. By the end of this lesson, students should understand how key structural features like the 1 - 4 and 1 - 6 glycosidic bonds and the hydrogen bonds dictate whether the polysaccharide chain is branched or unbranched and also whether it spirals or not. A range of activities are used to motivate and engage the students as they discover that glycogen is stored in liver and muscle cells, which it is able to do because of its compact structure. They are encouraged to discuss why the branched structure of this polysaccharide means that it can act as an immediate source of energy and they will recognise that hydrolysis reactions at the multiple ends of this chain will release glucose. Following on from the description of the structure of glycogen, students are challenged to design an exam question in the form of a comparison table so that it can be completed as the lesson progresses once they learn more about starch and cellulose. This includes a split in the starch section of the table so that the differing structures and properties of amylose and amylopectin can be considered. In the final part of the lesson, time is taken to focus on the formation of cellulose microfibrils and macrofibrils to explain how plant cells have the additional strength needed to support the whole plant. Due to the detail included in this lesson, it is estimated that it will take in excess of 2 hours of allocated teaching time to complete