This fully-resourced lesson distinguishes between active and passive, natural and artificial immunity and explains how vaccinations can be used to control disease. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 11.2 (d) of the CIE A-level Biology specification and there is also a description and discussion on the concept of herd immunity. In topic 11.1, students were introduced to the primary and secondary immune responses so the start of this lesson uses an imaginary game of TOP TRUMPS to challenge them on the depth of their understanding. This will act to remind them that a larger concentration of antibodies is produced in a quicker time in the secondary response. The importance of antibodies and the production of memory cells for the development of immunity is emphasised and this will be continually referenced as the lesson progresses. The students will learn that this response of the body to a pathogen that has entered the body through natural processes is natural active immunity. Moving forwards, time is taken to look at vaccinations as an example of artificial active immunity. Another series of questions focusing on the MMR vaccine will challenge the students to explain how the deliberate exposure to antigenic material activates the immune response and leads to the retention of memory cells. A quick quiz competition is used to introduce the variety of forms that the antigenic material can take along with examples of diseases that are vaccinated against using these methods. The eradication of smallpox is used to describe the concept of herd immunity and the students are given time to consider the scientific questions and concerns that arise when the use of this pathway is a possible option for a government. The remainder of the lesson looks at the different forms of passive immunity and describes the drawbacks in terms of the need for a full response if a pathogen is re-encountered

This lesson describes the differences between the primary and secondary responses and describes how the structure of antibodies is related to function. The PowerPoint and accompanying resources have been designed to cover specification points 4.1.1 (g), (h) and (i) as detailed in the OCR A-level Biology A specification and emphasises the importance of memory cells. As memory B cells differentiate into plasma cells that produce antibodies when a specific antigen is re-encountered, it was decided to link the immune responses and antibodies together in one lesson. The lesson begins by checking on the students incoming knowledge to ensure that they recognise that B cells differentiate into plasma cells and memory cells. This was introduced in a previous lesson on the specific immune response and students must be confident in their understanding if the development of immunity is to be understood. A couple of quick quiz competitions are then used to introduce key terms so that the structure of antibodies in terms of polypeptide chains, variable and constant regions and hinge regions are met. Time is taken to focus on the variable region and to explain how the specificity of this for a particular antigen allows neutralisation and agglutination to take place. The remainder of the lesson focuses on the differences between the primary and secondary immune responses and a series of exam-style questions will enable students to understand that the quicker production of a greater concentration of these antibodies in the secondary response is due to the retention of memory cells.

This fully-resourced lesson has been written to support students to develop a clear understanding of 16 key genetic terms, including the 8 that are detailed in specification point 8.2 (i) of the Edexcel A-level Biology B specification. The 16 terms are genome, gene, chromosome, gene locus, homologous chromosomes, alleles, dominant, recessive, genotype, codominance, multiple alleles, autosomes, sex chromosomes, phenotype, homozygous and heterozygous. As some of these terms were met at GCSE, this fully-resourced lesson has been designed to include a wide range of activities that build on this prior knowledge and provide clear explanations as to their meanings as well as numerous examples of their use in both questions and exemplary answers. The main task provides the students with an opportunity to apply their understanding by recognising a dominance hierarchy in a multiple alleles characteristic and then calculating a phenotypic ratio when given a completed genetic diagram. Other tasks include prior knowledge checks, discussion points to encourage students to consider the implementation of the genetic terms and quiz competitions to introduce new terms, maintain engagement and to act as an understanding check.

This lesson guides students through the use of the chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated worksheets that have been designed to cover point 8.2 (vi) of the Edexcel A-level Biology B specification The lesson includes a step-by-step guide to demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty. This is the final lesson of topic 8.2 (transfer of genetic information) and links are made throughout the lesson to earlier parts of this topic such as dihybrid inheritance as well as to earlier topics like meiosis

This lesson describes the roles of phosphate, calcium, magnesium and nitrate ions in plants. The PowerPoint and accompanying resources have been designed to cover the content of point 1.6 of the Edexcel A-level biology B specification. The lesson begins by challenging the students to recognise DNA, RNA and phospholipids from three clues, and then they are challenged to recognise that these three biological molecules all contain phosphate ions. Moving forwards, a quick quiz round introduces adenosine triphosphate (ATP) and the students will learn that this is a phosphorylated nucleotide which can be hydrolysed to ADP to release energy. Time is taken to explain how this energy can be coupled to processes within cells such as active transport and examples in plants including the absorption of mineral ions and active loading in the phloem are explored. The rest of the lesson describes the role of magnesium in the production of chlorophyll, nitrates to make DNA and amino acids and calcium ions to form calcium pectate in the middle lamellae. There are multiple understanding checks and also prior knowledge checks, where the students recall of the structure and function of haemoglobin is challenged.

This lesson describes the role of reduced NAD and FAD as sources of electrons and protons for the electron transport system. The PowerPoint has been designed to cover the content of topic 3 point (d) of A2 unit 3 as set out in the WJEC A-level biology specification and explains how ATP is produced by oxidative phosphorylation. The lesson begins with a recognition that the start of this stage doesn’t have a carbon-based molecule as was observed with the Krebs cycle. This leads into a discussion period, where the students are challenged to study their notes on glycolysis and the Krebs cycle to suggest which products of these reactions could initiate this stage. This introduces the reduced coenzymes as the sources of electrons and protons for the electron transport system, and as shown in the cover image, a step-by-step guide walks the students through the key parts of this stage. Students will learn about the creation of a proton gradient across the inner mitochondrial membrane and the formation of ATP and water when oxygen acts as the final electron acceptor. This lesson is a follow-on lesson from the previous lessons covering the Krebs cycle, glycolysis and the need for respiration.

This lesson describes the meaning of absorption and action spectra and explains why plants contain several photosynthetic pigments. The PowerPoint and accompanying resources have been designed to cover both specification points in topic 5.6 of the Edexcel A-level biology B specification and includes key information to prepare the students for the photosynthesis lessons in topic 5.7. The students are presented with a picture of a leaf with chlorosis at the start of the lesson and are challenged to explain the appearance and name the ion which is deficient in the soil, drawing on their knowledge from topic 1. The lesson has been intricately planned to build on their limited knowledge of photosynthesis from GCSE, and to introduce key details such as the location of chlorophyll in the photosystems in the thylakoids. The students will learn that there are two forms of chlorophyll a, as well as a chlorophyll b, and a quick quiz round is used to reveal the values of 680 and 700. The absorption spectrum for chlorophyll a and b are displayed and when the students are presented with a spectra, they will discover that there are more chloroplast pigments. The carotenoids are introduced and the students have to interpret the spectra to reveal more details about these pigments. The meaning of an action spectrum is provided and the students are challenged to draw a sketch graph to show how the rate of photosynthesis differs for different wavelengths, before the correlation between the two spectra is considered.

This lesson describes the importance of photosynthetic pigments in photosynthesis. The PowerPoint and accompanying resources are part of the 1st lesson in a series of 2 lessons which have been designed to cover point [c]of module 5.2.1 of the OCR A-level biology A specification and include descriptions of the role of the chlorophylls, carotene and xanthophyll and explains how to interpret absorption and action spectra. . The students are presented with a picture of a leaf with chlorosis at the start of the lesson and are challenged to explain the appearance by drawing on any knowledge from GCSE. The lesson has been intricately planned to build on the previous lesson on the structure of the chloroplast, and the students are reminded that chlorophyll is located in the thylakoids. The students will learn that there are two forms of chlorophyll a, as well as a chlorophyll b, and a quick quiz round is used to reveal the values of 680 and 700. The absorption spectrum for chlorophyll a and b are displayed and when the students are presented with a spectra, they will discover that there are more chloroplast pigments. The carotenoids are introduced and the students have to interpret the spectra to reveal more details about these pigments. The meaning of an action spectrum is provided and the students are challenged to draw a sketch graph to show how the rate of photosynthesis differs for different wavelengths. Due to the similarities in the structure and function between haemoglobin and chlorophyll, the final task is a prior knowledge check about this protein.

This lesson describes the meaning of the absorption and action spectrum and explains how to interpret these graphs. The PowerPoint and accompanying resources have been designed to cover point 5.6 of the Edexcel International A-level biology specification and includes descriptions of the roles of the photosynthetic pigments to link to content covered in the earlier lessons in topic 5. The students are presented with a picture of a leaf with chlorosis at the start of the lesson and are challenged to explain the appearance and name the ion which is deficient in the soil, drawing on their knowledge from topics 4 and 5. The lesson has been intricately planned to build on the previous lessons on the structure of the chloroplast and the reactions of photosynthesis, and the students are reminded that chlorophyll is located in the photosystems in the thylakoids. The students will learn that there are two forms of chlorophyll a, as well as a chlorophyll b, and a quick quiz round is used to reveal the values of 680 and 700. The absorption spectrum for chlorophyll a and b are displayed and when the students are presented with a spectra, they will discover that there are more chloroplast pigments. The carotenoids are introduced and the students have to interpret the spectra to reveal more details about these pigments. The meaning of an action spectrum is provided and the students are challenged to draw a sketch graph to show how the rate of photosynthesis differs for different wavelengths.

This lesson uses real-life examples in plants and animals to explain the need for all living organisms to carry out respiration to provide energy. The PowerPoint and accompanying resources have been designed to cover the content of topic 3 point (a) of A2 unit 3 as detailed in the WJEC A-level Biology specification but can also be used as a revision tool to challenge the students on their knowledge of active transport. As the first lesson in this topic, it has been specifically planned to act as an introduction to this cellular reaction and provides important details about glycolysis, the Krebs cycle and oxidative phosphorylation that will support the students to make significant progress when these stages are covered during upcoming lessons. Students met phosphorylation in topic 2 when considering the light-dependent reactions of photosynthesis and their knowledge of the production of ATP in this plant cell reaction is challenged in this lesson. The students are also tested on their recall of the structure and function of ATP, as covered in AS unit 1, topic 5, through a spot the errors task. By the end of the lesson, the students will be able to explain why the ATP produced in cellular respiration is needed by root hair cells and by companion cells and will be introduced to uses in animals too, such as nervous transmission. They will also be able to name and describe the different types of phosphorylation and will know that ATP is produced by substrate-level phosphorylation in glycolysis and the Krebs cycle and by oxidative phosphorylation in the final stage of aerobic respiration.

This lesson describes how lipids and amino acids are used in respiration, as an alternative to glucose. The PowerPoint and accompanying resources have been designed to cover the content of topic 3 point (f) of A2 unit 3 as set out in the WJEC A-level biology specification. The lesson begins with a challenge, where the students have to recognise the key term substrate using either 1 or 2 descriptions. The definition of a respiratory substrate is provided and students will learn that although glucose is the chief respiratory substrate, lipids and amino acids can be metabolised to generate molecules of ATP. A quick quiz round is used to introduce the relative energy value per gram of carbohydrate and then this is used as a reference value for the remainder of the lesson. Students will learn that the energy value is higher for lipids and this is explained, making reference to the proton gradient in the final stage of aerobic respiration. The final part of the lesson considers amino acids and makes a link to deamination, and explores how the entry point into respiration depends upon the keto acid which was formed. The lesson contains multiple understanding checks and all answers are embedded into the PowerPoint to allow students to assess their progress.

This lesson describes the importance of water and inorganic ions in plants. The PowerPoint and accompanying resources have been designed to cover the content of point 4.8 of the Edexcel International A-level biology specification, and includes details of the roles of nitrate, calcium and magnesium ions. In an earlier lesson, the students explored the relationship between the structure and function of the xylem vessel, so this lesson describes how the properties of water allow movement through the tissue. The students will understand how hydrogen bonds between water molecules leads to cohesion and this coupled with tension, causes the column of water to be pulled towards the leaves by the transpiration pull. Their knowledge and understanding of the role of water in hydrolysis and condensation reactions is challenged, before the role of water as a transport medium for multiple substances, including inorganic ions, is discussed. The rest of the lesson describes the role of magnesium in the production of chlorophyll, nitrates to make DNA and amino acids and calcium ions to form calcium pectate in the middle lamellae. There are multiple understanding checks and also prior knowledge checks, where the students recall of the structure and function of the vacuole and haemoglobin are challenged.

This lesson describes the role of the chlorophylls, carotene and xanthophyll and explains how to interpret absorption and action spectra. The PowerPoint and accompanying resources have been designed to cover points 4 and 5 in topic 13.1 of the CIE A-level biology specification. The students are presented with a picture of a leaf with chlorosis at the start of the lesson and are challenged to explain the appearance by drawing on any knowledge from GCSE. The lesson has been intricately planned to build on the previous lesson on the structure of the chloroplast, and the students are reminded that chlorophyll is located in the thylakoids. The students will learn that there are two forms of chlorophyll a as well as a chlorophyll b, and a quick quiz round is used to reveal the values of 680 and 700. The absorption spectrum for chlorophyll a and b are displayed and when they are presented with a spectra, the students will discover that there are more chloroplast pigments. The carotenoids are introduced and the students have to interpret the spectra to reveal more details about these pigments. The meaning of an action spectrum is provided and the students are challenged to draw a sketch graph to show how the rate of photosynthesis differs for different wavelengths.

This lesson describes the importance of water and calcium, magnesium and nitrate ions in plants. The PowerPoint and accompanying resources have been designed to cover the content of point 4.12 of the Pearson Edexcel A-level biology A (SNAB) specification. In the previous lesson, the students explored the relationship between the structure and function of the xylem vessel, so this lesson describes how the properties of water allow movement through the tissue. The students will understand how hydrogen bonds between water molecules leads to cohesion and this coupled with tension, causes the column of water to be pulled towards the leaves by the transpiration pull. Their knowledge and understanding of the role of water in hydrolysis and condensation reactions is challenged, before the role of water as a transport medium for multiple substances, including inorganic ions, is discussed. The rest of the lesson describes the role of magnesium in the production of chlorophyll, nitrates to make DNA and amino acids and calcium ions to form calcium pectate in the middle lamellae. There are multiple understanding checks and also prior knowledge checks, where the students recall of the structure and function of haemoglobin is challenged.

This lesson describes how chloroplast pigments can be separated by chromatography and the pigments identified by Rf values. The PowerPoint and accompanying resource have been planned to cover point 5.7 of the Edexcel International A-level biology specification and to build and check on the knowledge acquired in the previous lesson on the absorption and action spectrum. The lesson begins with a challenge, where the students must recall that chromatography is the separation method that has a stationary and a mobile phase and then to realise that the chloroplast pigments could be separated using this technique. A step-by-step guide goes through the thin-layer chromatography process, and understanding and prior knowledge checks are used throughout to add key details. Moving forwards, the formula for the retention factor is provided, and the students are challenged to apply this formula to recognise the values for the chlorophylls and the carotenoids to allow them to be identified. All answers to the understanding and prior knowledge checks are embedded into the PowerPoint to allow students to assess their progress.

This lesson describes how thin-layer chromatography can be used to separate photosynthetic pigments. The PowerPoint and accompanying resource are part of the 2nd lesson in a series of 2 lessons which have been planned to cover point [c] of module 5.2.1 of the OCR A-level biology A specification. As mentioned above, this lesson has been designed to build and check on knowledge from the previous lesson which covered the importance of the photosynthetic pigments. The lesson begins by challenging them to recall that chromatography is the separation method that has a stationary and a mobile phase and then to realise that the photosynthetic pigments could be separated using this technique. A step-by-step guide goes through the TLC process, and understanding and prior knowledge checks are used throughout to add key details. Moving forwards, the formula for the retention factor is provided, and the students are challenged to apply this formula to recognise the values for the chlorophylls and the carotenoids. All answers to the understanding and prior knowledge checks are embedded into the PowerPoint to allow students to assess their progress.

This lesson describes how to use thin-layer chromatography to separate and identify chloroplast pigments. The PowerPoint and accompanying resource have been planned to cover point (6) of topic 13.1 of the CIE A-level biology specification and to build and check on the knowledge acquired in the previous two lessons on the structure of the chloroplast and photosynthesis and the chloroplast pigments. As shown in the cover image, the lesson begins by challenging them to recall that chromatography is the separation method that has a stationary and a mobile phase and then to realise that the chloroplast pigments could be separated using this technique. A step-by-step guide goes through the TLC process, and understanding and prior knowledge checks are used throughout to add key details. Moving forwards, the formula for the retention factor is provided, and the students are challenged to apply this formula to recognise the values for the chlorophylls and the carotenoids to allow them to be identified. All answers to the understanding and prior knowledge checks are embedded into the PowerPoint to allow students to assess their progress.